The given presentations share a specific use case from the medical field of oncology and outlines the potentials of applying artificial intelligence to it.

1. Artificial Intelligence in Oncology
Dr.-Ing. Matthieu-P. Schapranow
MedTech Summit, Nuremberg
May 23, 2019

2. ■ Case vignette: 65-year old, male, former smoker, COPD patient
■ How does the patient journey looks like?
Patient Journey: Lung Cancer in 2024
Screening, Diagnosis, Treatment, and Prevention
Schapranow, MedTech
Summit, May 23, 2019
AI in Oncology
2

3. ■ Case vignette: 65-year old, male, former smoker, COPD patient
■ How does the patient journey looks like?
Patient Journey: Lung Cancer in 2024
Screening, Diagnosis, Treatment, and Prevention
Schapranow, MedTech
Summit, May 23, 2019
AI in Oncology
3

4. ■ Personal risk score based on patient anamnesis, e.g. COPD or
former smoker
■ Regular check-ups supported through direct notifications, e.g.
annual respiratory screening recommended
Patient Journey: Lung Cancer in 2024
Screening
Schapranow, MedTech
Summit, May 23, 2019
AI in Oncology
4

5. ■ Lung function test
■ Low-dose CT scan of the lung
■ AI system supports radiologists in detecting lung tissue changes
■ Minimal invasive CTC test reveals cells carrying relevant genetic
changes, e.g. EGFR+ and ERBB2+
■ Biopsy from lung validated hypothesis
Patient Journey: Lung Cancer in 2024
Diagnosis
Schapranow, MedTech
Summit, May 23, 2019
AI in Oncology
5
https://www.plattform-lernende-systeme.de/anwendungsszenario-2.html

6. ■ AI-based therapy support based on, e.g.
□ Clinical guidelines
□ International medical knowledge
□ Access to latest publications
■ à Surgery can be performed
Patient Journey: Lung Cancer in 2024
Treatment
Schapranow, MedTech
Summit, May 23, 2019
AI in Oncology
6
https://we.analyzegenomes.com/mkc/digiGipfel2018/

7. ■ Comparison of similar patients
■ Quantitative real-time analysis of therapy efficiency
■ Assessment of alternative therapy options
■ Bring clinical trials based on patient specifics
to individual patients
■ à Adjuvant therapy based on specific
combination of chemotherapy is performed
Patient Journey: Lung Cancer in 2024
Treatment
Schapranow, MedTech
Summit, May 23, 2019
AI in Oncology
7
https://we.analyzegenomes.com/mkc/digiGipfel2018/

8. ■ Federal Institute of Digital Health (DH), e.g.
□ Maintains population data for a healthier society
□ Provides access to subject-matter experts
□ Supports development of innovative DH solutions
■ Data Donation Pass as citizen-facing tool:
□ Enable sovereign use of healthcare data
□ Control access to personal healthcare data, e.g. grant
access to family members
□ Donate de-identified data for a healthier society, e.g.
to support specific research projects
Patient Journey: Lung Cancer in 2024
Prevention
Schapranow, MedTech
Summit, May 23, 2019
AI in Oncology
8
https://we.analyzegenomes.com/apps/data-donation-pass/

9. ■ 150 MEUR national initiative to support adaption of digital health
■ HiGHmed consists of international partners from, e.g. hospitals,
academia, and industry.
■ Clinical Use Cases
□ Oncology
□ Cardiology
□ Infection control
■ Education: Curriculum for experts, e.g. data scientists, data stewards
Medical Informatics Initiative
HiGHmed Consortium
Schapranow, MedTech
Summit, May 23, 2019
AI in Oncology
9

10. Our Approach: AnalyzeGenomes.com
In-Memory Computing Platform for Big Medical Data
Schapranow, MedTech
Summit, May 23, 2019
AI in Oncology
10
In-Memory Computing Platform
Extensions for Life Sciences
Data Exchange,
App Store
Access Control,
Data Protection
Fair Use
Statistical
Tools
Real-time
Analysis
App-spanning
User Profiles
Combined and Linked Data
Genome
Data
Cellular
Pathways
Genome
Metadata
Research
Publications
Pipeline and
Analysis Models
Drugs and
Interactions
Drug Response
Analysis
Pathway Topology
Analysis
Medical
Knowledge CockpitOncolyzer
Clinical Trial
Recruitment
Cohort
Analysis
...
Indexed
Sources

11. Stay in Contact!
Dr.-Ing. Matthieu-P. Schapranow
Working Group Leader &
Scientific Manager Digital Health Innovations
Digital Health Center
Hasso Plattner Institute Campus III,
Rudolf-Breitscheid-Str. 187
14482 Potsdam, Germany
we.analyzegenomes.com
@AnalyzeGenomes
Schapranow, MedTech
Summit, May 23, 2019
AI in Oncology
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