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Improving the HIV Cascade of
Services in Vietnam
ICAAP Bangkok
November 2013
Outline
• Current Response to the HIV epidemic in
Vietnam
• Impact of recent research in stimulating major
changes to program approaches
• The Cascade Framework
– Vietnam cascade
– Provincial rapid assessments
– Findings and actions

• Implications for planning/investments
Response to HIV epidemic
in Vietnam
Response to HIV epidemic in Vietnam
• Nearly 72,000 on ART
• More than 14,500 on MMT (Target 80,000 by 2015)
• Number of newly reported HIV diagnoses has declined
• New generation of well trained, experienced leaders
emerging
• Country leadership on HIV/AIDS is gaining in strength
• New mountainous province initiative
Concerning trends in Vietnam
1. Substantial, local HIV
epidemics occurring in
underserved areas.
2. Many PLHIV often not seeking
testing or not linked to care
after testing positive.
3. Number newly initiating ART
not growing or declining in
many sites.
Concerning trends in Vietnam
4. Many clients are dying, dropping out of
treatment or lost to follow-up
5. Coordination of service systems is fragmented
and project-focused.
6. Donor resources declining and service system
costs too high to be sustained by the GVN.
7. Epidemic of injection drug use continues with
>215,000 estimated PWID.
Injection Drug Use Trends in Vietnam
Late Entry to ART
“At present, 51% of people start treatment at a
CD4 cell count below 100 cells/mm3, underlining
the urgency of expanding access to treatment,
regardless of its prevention benefit.”
Dr Bui Duc Duong, Deputy Director-General
Viet Nam Authority of HIV/AIDS Control
7th International AIDS Society Conference on HIV
Pathogenesis, Treatment and Prevention. Kuala
Lumpur, Malaysia (July 2013)
Research findings are stimulating
new program approaches
Recent Studies of MMT and ART
• MMT - Systematic review found that recipients reduce
their HIV risks by 54%.
Macarthur, et. Al., October 2012

• Cost Effectiveness:
– HIV counseling and testing with “immediate” ART targeted
to PWID can greatly reduce new infections and be “cost
saving”
Kato, et. al., 2013
– Systematic review of 36 studies in developing countries
found ART and MMT to be cost effective in all.
West and Nguyen, 2013 Report
Research is making program goals clearer
• “Knowing HIV positive status ” will lead to reduced individual
behavioral risk.

• Viral load (VL) is directly related to increased HIV transmission
risks.
• Suppressing VL through ART substantially reduces HIV
transmission risks.
• Methadone maintenance reduces HIV risks (HIV positive and
negative) among PWID.
• Priority goals include: 1) increasing the number of PLHIV who
know their status, 2) reducing viral load through sustained
ART and 3) increasing access of PWID to MMT.
The Cascade Framework in
Vietnam
The Cascade framework is…
• Old, but new
• Improvement on older methods for presenting data &
illustrating program performance
• Simple, easy to communicate with powerful impact
• Scalable from province to national
• Easily adaptable to different programs, strategies and
populations
• Promotes different interventions targeted to different
phases of - or gaps in - the cascade
The Cascade is…
• Based on a set of available core indicators
• A logic model that links prevention outreach,
testing & treatment services across a continuum
of care (CoPC)
• Reveals how individuals move, don’t move,
through the CoPC or are lost to follow-up
• Identifies areas where “plugging” leaks will lead
to higher performing service systems with more
impact
The Cascade Framework: Patching a Leaky Pipe
The Cascade Framework

- Extension of life
- Reduce transmission
Preliminary Cascade for Vietnam, June
2012
100%

51,165 potential PLHIV not
diagnosed

248,500

118,401 PLHIV not
engaged and retained in
care

197,335
80%

80%
60%

77%
98, 668

100%

40%

51%
78,934

79%
40%

20%

32%

89%
67,000

77%

27%

0%
HIV Infected*

HIV Diagnosed

Linked to HIV
Care**

HIV Retained in
HIV Care

On ART***

?

Suppressed viral
load (<500
copies/ml)

Vietnam AIDS Response Progress Report 2012. National Committee for AIDS, Drugs and Prostitution Prevention and Control. March 2012. **
Assumes 70% uptake from HTC to OPC (nationally) *** Current estimate based on verbal report from SCMS
Cascade of HIV diagnosis,
care and treatment in
Vietnam, Dec, 2012
250000
200000
Female

Person

63537

Male

150000
100000
44%

138166

28262

50000
39%

53979

87%
88%

24785
47926

0
Diagnosed PLHIV
Source: VAAC report, D28

In care at OPC

On ART
Cascade for Hanoi, December 2012
18000
16000

3514

14000

Person

12000

Female

Male

10000
60%

8000
6000

13543
2107
83%

4000
33%

2000

4470

1743

80%

3599

0
Diagnosed PLHIV
Source: Hanoi PAC, D28, 2012; HIV INFO/VAAC, 10/2013

In care

On ARV
Rapid Assessments and Responses
• Four provinces assessed: Nghe An, Lao
Cai, Dien Bien and An Giang (three more
scheduled)
• Cascade framework coupled with service
mapping used to assess CoPC performance
and needs.
• Targeted, time limited assistance plan rapidly
implemented (in phases)
• Cost assessment and analyses being added
Cascade for Nghe An, Dec 2012
5000
4500
4000

1583

Person

3500

Female

Male

3000
2500
2000

35%

3088

1500
1000

562
40%

1234

500

95%

95%

538

1176

0
Diagnosed PLHIV
Source: Nghe An PAC, 2012

In care

On ARV
Cascade for Lao Cai, 6/2013
3500
3000

Person

2500

1390

Female

Male

2000
1500
1000

1778

20%

276

500

27%

84%

477

80%

0
Diagnosed PLHIV
Source: Lao Cai PAC, 10/2013

In care

232
381
On ARV
Cascade for Dien Bien, 6/2013
9000
8000
7000

7782
81.78%

6364

6000
5000
4000
3000

27.36%

2000

1741

92.82%

1616

1000
0
Accumulative HIV
reported cases

PLHIV still alive

Retain in care

Currently on ARV
Dien Bien Dong District, Aug 2013
900

800

700

183

600

500

Death
400

300

PLHIV
597

555

200

100

131
0

H+ cumulative

HIV+ Managed

on ARV
Tua Chua District, Aug 2013
100
90
80

35
70
60
50

Death

40

PLHIV

30

57

20

38

10

6

0

H+ cumulative

HIV+ Managed

on ARV
Muong Bang Commune, Aug 2013
60

50

40

20

30

Death
PLHIV

20

28
10

16
2

0

H+ cumulative

HIV+ Managed

on ARV
Tua Chua Town-ship, Aug 2013
30

25

10
20

15

Death
PLHIV

10

17
14
5

2

0

H+ cumulative

HIV+ Managed

on ARV
Other Cascades
MMT – HIV – ART Cascade, Dec 2012
40,000

Data Source: VAAC 2012

Estimated:
217,000

35,000

Recorded:
171,000
30,000

121
Drug
‘06 Centers
25,000

Methadone Maintenance

Users

25-35,000
MMT Retention:
Haiphong
1 Year 90%
2 Years 80%

20,000

15,000

10,000

5,000

13,000
60
MMT
Clinics

HIVNegative
77.5%

13,000
HIV+ 22.5%

2,925

ARV 71.4%

0

IDU's

MMT

ART
Implications for planning and
investment
The Cascade Framework in Vietnam…
• A useful planning/diagnostic tool,
• Easily used at the provincial level
• Rapid assessments/responses can lead to closing of
service gaps/leaks

• Useful for monitoring/evaluating introduction of
new tools/approaches and a wide range of health
issues
Investments in ….
• Use of the cascade framework coupled with
service mapping and cost assessment can be
very effective.
• Addressing targeted gaps and leaks will
substantially Improve system performance.
• Supporting local use of the cascade
framework can increase sustainability.

• Investment in the framework is well justified.
THANK YOU!
Nghe An Mineral Deposits

Source:
http://idm.gov.vn/Nguon_luc/Ban_do/Khoang_san/
Khoang_san_tinh/Nghean/NgheAn_index.htm
New TB/HIV Cases in Quy Chau

56% of cases with SSor extrapulmonary TB
with 20% HIV+ rate

2012

First half of 2013
HTC test in Dien Bien
Number of HTC test decreased from 2010 to August 2013 and
HIV+ trend also decreased
18000

100.0%
90.0%

15424

16000

80.0%

14000

12602
70.0%

12000

10199

60.0%

Number of HIV test

10000
50.0%
8000

6360

40.0%

6000
30.0%

4642
4000

20.0%

2000

10.0%

0

0.0%
2009

2010

2011

2012

Aug-13

HIV+ through HTC
Case reporting

% of HIV+

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Improving the HIV Cascade of Services in Vietnam

  • 1. Improving the HIV Cascade of Services in Vietnam ICAAP Bangkok November 2013
  • 2. Outline • Current Response to the HIV epidemic in Vietnam • Impact of recent research in stimulating major changes to program approaches • The Cascade Framework – Vietnam cascade – Provincial rapid assessments – Findings and actions • Implications for planning/investments
  • 3. Response to HIV epidemic in Vietnam
  • 4. Response to HIV epidemic in Vietnam • Nearly 72,000 on ART • More than 14,500 on MMT (Target 80,000 by 2015) • Number of newly reported HIV diagnoses has declined • New generation of well trained, experienced leaders emerging • Country leadership on HIV/AIDS is gaining in strength • New mountainous province initiative
  • 5. Concerning trends in Vietnam 1. Substantial, local HIV epidemics occurring in underserved areas. 2. Many PLHIV often not seeking testing or not linked to care after testing positive. 3. Number newly initiating ART not growing or declining in many sites.
  • 6. Concerning trends in Vietnam 4. Many clients are dying, dropping out of treatment or lost to follow-up 5. Coordination of service systems is fragmented and project-focused. 6. Donor resources declining and service system costs too high to be sustained by the GVN. 7. Epidemic of injection drug use continues with >215,000 estimated PWID.
  • 7. Injection Drug Use Trends in Vietnam
  • 8. Late Entry to ART “At present, 51% of people start treatment at a CD4 cell count below 100 cells/mm3, underlining the urgency of expanding access to treatment, regardless of its prevention benefit.” Dr Bui Duc Duong, Deputy Director-General Viet Nam Authority of HIV/AIDS Control 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention. Kuala Lumpur, Malaysia (July 2013)
  • 9. Research findings are stimulating new program approaches
  • 10. Recent Studies of MMT and ART • MMT - Systematic review found that recipients reduce their HIV risks by 54%. Macarthur, et. Al., October 2012 • Cost Effectiveness: – HIV counseling and testing with “immediate” ART targeted to PWID can greatly reduce new infections and be “cost saving” Kato, et. al., 2013 – Systematic review of 36 studies in developing countries found ART and MMT to be cost effective in all. West and Nguyen, 2013 Report
  • 11.
  • 12. Research is making program goals clearer • “Knowing HIV positive status ” will lead to reduced individual behavioral risk. • Viral load (VL) is directly related to increased HIV transmission risks. • Suppressing VL through ART substantially reduces HIV transmission risks. • Methadone maintenance reduces HIV risks (HIV positive and negative) among PWID. • Priority goals include: 1) increasing the number of PLHIV who know their status, 2) reducing viral load through sustained ART and 3) increasing access of PWID to MMT.
  • 13. The Cascade Framework in Vietnam
  • 14. The Cascade framework is… • Old, but new • Improvement on older methods for presenting data & illustrating program performance • Simple, easy to communicate with powerful impact • Scalable from province to national • Easily adaptable to different programs, strategies and populations • Promotes different interventions targeted to different phases of - or gaps in - the cascade
  • 15. The Cascade is… • Based on a set of available core indicators • A logic model that links prevention outreach, testing & treatment services across a continuum of care (CoPC) • Reveals how individuals move, don’t move, through the CoPC or are lost to follow-up • Identifies areas where “plugging” leaks will lead to higher performing service systems with more impact
  • 16. The Cascade Framework: Patching a Leaky Pipe
  • 17. The Cascade Framework - Extension of life - Reduce transmission
  • 18. Preliminary Cascade for Vietnam, June 2012 100% 51,165 potential PLHIV not diagnosed 248,500 118,401 PLHIV not engaged and retained in care 197,335 80% 80% 60% 77% 98, 668 100% 40% 51% 78,934 79% 40% 20% 32% 89% 67,000 77% 27% 0% HIV Infected* HIV Diagnosed Linked to HIV Care** HIV Retained in HIV Care On ART*** ? Suppressed viral load (<500 copies/ml) Vietnam AIDS Response Progress Report 2012. National Committee for AIDS, Drugs and Prostitution Prevention and Control. March 2012. ** Assumes 70% uptake from HTC to OPC (nationally) *** Current estimate based on verbal report from SCMS
  • 19. Cascade of HIV diagnosis, care and treatment in Vietnam, Dec, 2012 250000 200000 Female Person 63537 Male 150000 100000 44% 138166 28262 50000 39% 53979 87% 88% 24785 47926 0 Diagnosed PLHIV Source: VAAC report, D28 In care at OPC On ART
  • 20. Cascade for Hanoi, December 2012 18000 16000 3514 14000 Person 12000 Female Male 10000 60% 8000 6000 13543 2107 83% 4000 33% 2000 4470 1743 80% 3599 0 Diagnosed PLHIV Source: Hanoi PAC, D28, 2012; HIV INFO/VAAC, 10/2013 In care On ARV
  • 21. Rapid Assessments and Responses • Four provinces assessed: Nghe An, Lao Cai, Dien Bien and An Giang (three more scheduled) • Cascade framework coupled with service mapping used to assess CoPC performance and needs. • Targeted, time limited assistance plan rapidly implemented (in phases) • Cost assessment and analyses being added
  • 22. Cascade for Nghe An, Dec 2012 5000 4500 4000 1583 Person 3500 Female Male 3000 2500 2000 35% 3088 1500 1000 562 40% 1234 500 95% 95% 538 1176 0 Diagnosed PLHIV Source: Nghe An PAC, 2012 In care On ARV
  • 23. Cascade for Lao Cai, 6/2013 3500 3000 Person 2500 1390 Female Male 2000 1500 1000 1778 20% 276 500 27% 84% 477 80% 0 Diagnosed PLHIV Source: Lao Cai PAC, 10/2013 In care 232 381 On ARV
  • 24. Cascade for Dien Bien, 6/2013 9000 8000 7000 7782 81.78% 6364 6000 5000 4000 3000 27.36% 2000 1741 92.82% 1616 1000 0 Accumulative HIV reported cases PLHIV still alive Retain in care Currently on ARV
  • 25. Dien Bien Dong District, Aug 2013 900 800 700 183 600 500 Death 400 300 PLHIV 597 555 200 100 131 0 H+ cumulative HIV+ Managed on ARV
  • 26. Tua Chua District, Aug 2013 100 90 80 35 70 60 50 Death 40 PLHIV 30 57 20 38 10 6 0 H+ cumulative HIV+ Managed on ARV
  • 27. Muong Bang Commune, Aug 2013 60 50 40 20 30 Death PLHIV 20 28 10 16 2 0 H+ cumulative HIV+ Managed on ARV
  • 28. Tua Chua Town-ship, Aug 2013 30 25 10 20 15 Death PLHIV 10 17 14 5 2 0 H+ cumulative HIV+ Managed on ARV
  • 30.
  • 31. MMT – HIV – ART Cascade, Dec 2012 40,000 Data Source: VAAC 2012 Estimated: 217,000 35,000 Recorded: 171,000 30,000 121 Drug ‘06 Centers 25,000 Methadone Maintenance Users 25-35,000 MMT Retention: Haiphong 1 Year 90% 2 Years 80% 20,000 15,000 10,000 5,000 13,000 60 MMT Clinics HIVNegative 77.5% 13,000 HIV+ 22.5% 2,925 ARV 71.4% 0 IDU's MMT ART
  • 32. Implications for planning and investment
  • 33. The Cascade Framework in Vietnam… • A useful planning/diagnostic tool, • Easily used at the provincial level • Rapid assessments/responses can lead to closing of service gaps/leaks • Useful for monitoring/evaluating introduction of new tools/approaches and a wide range of health issues
  • 34. Investments in …. • Use of the cascade framework coupled with service mapping and cost assessment can be very effective. • Addressing targeted gaps and leaks will substantially Improve system performance. • Supporting local use of the cascade framework can increase sustainability. • Investment in the framework is well justified.
  • 36. Nghe An Mineral Deposits Source: http://idm.gov.vn/Nguon_luc/Ban_do/Khoang_san/ Khoang_san_tinh/Nghean/NgheAn_index.htm
  • 37. New TB/HIV Cases in Quy Chau 56% of cases with SSor extrapulmonary TB with 20% HIV+ rate 2012 First half of 2013
  • 38. HTC test in Dien Bien Number of HTC test decreased from 2010 to August 2013 and HIV+ trend also decreased 18000 100.0% 90.0% 15424 16000 80.0% 14000 12602 70.0% 12000 10199 60.0% Number of HIV test 10000 50.0% 8000 6360 40.0% 6000 30.0% 4642 4000 20.0% 2000 10.0% 0 0.0% 2009 2010 2011 2012 Aug-13 HIV+ through HTC Case reporting % of HIV+

Notas do Editor

  1. Vietnamese graph title. We need to redo the graph as this graph is in picture format.
  2. HIV infected – EPP (2011); HIV diagnosed VAAC (2011)It is estimated that 50 % of diagnosed cases enrolled care and treatment program (Data from a quick assessment in Can Tho: 60% and HaiPhong 44%)It is estimated that 80% retained in care and treatment after 1 year. It is reported that 67,000 people are under ARV by June 2012
  3. I would need to check this with Suresh. As far as I understand, this is quite complicated and most based on estimated number. We have not been able to re-produce the graph for provinces with real data. Not sure about the time of this cascade. Please check with Suresh as well
  4. Mines are concentrated around mineral deposits. Most are near Que Chau and Que Phong.
  5. HIV+ persons much more likely to develop TB