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aspartame (non-saccharide sweetener)

Publicada em: Saúde e medicina
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  2. 2. PRESENTED TO: Ms. Mobeena PRESENTED BY: Rida ABID Pharm-D (4th Prof) 2012-2017 Institute of Pharmacy
  3. 3. ASPARTAME Aspartame is an artificial, non-saccharide sweetener used as a sugar substitute in some foods and beverages. In the European Union, it is codified as E951. According to the American Cancer Society, aspartame is approximately 200 times sweeter than sugar.
  4. 4. The ingredients of aspartame are aspartic acid and phenylalanine. Both are naturally occurring amino acids. Aspartic acid is produced by your body and phenylalanine is an essential amino acid that you get from food. When your body processes aspartame, part of it is broken down into methanol. Although toxic in large quantities, small quantities of methanol are not toxic. CHEMISTRY
  5. 5. 1.Aspartame is a natural sweetener that is sold under the brand names NutraSweet and Equal. 2.It is commonly found in “diet” foods. 3.While the sweetener remains popular, it has also faced controversy in recent years. 4.Many opponents have claimed that aspartame is actually bad for your health. 5.The FDA approves of aspartame, recommending a maximum daily intake of 50 milligrams per kilogram of body weight.
  6. 6. Aspartame Approvals: • Food and Drug Administration (FDA) • United Nations Food and Agriculture Organization • World Health Organization • American Heart Association • American Dietetic Association FDA banned the artificial sweeteners cyclamate (Sucaryl) and saccharin (Sweet’N Low).
  7. 7. Some examples of aspartame-containing products include: •diet soda •reduced calorie fruit juice •gum •yogurt •sugarless candy and baked goods ASPARTAME CONTAINING PRODUCTS
  8. 8. •FDA: 50 milligrams per kilogram of body weight •EFSA: 40 milligrams per kilogram of body weight A can of diet soda contains about 185 milligrams of aspartame. A 150-pound (68-kilogram) person would have to drink more than 18 cans of soda a day to exceed the FDA daily intake. Alternately, they would need nearly 15 cans to exceed the EFSA recommendation.
  9. 9. Phenylketonuria People with phenylketonuria have too much phenylalanine in their blood. Phenylalanine is an essential amino acid found in protein sources such as meat, fish, eggs, and dairy products. It is also one of the two ingredients of aspartame. People with this condition aren’t able to properly process phenylalanine. If you have this condition, aspartame is highly toxic. Tardive Dyskinesia Tardive dyskinesia (TD) is thought to be a side effect of some schizophrenia medications. The phenylalanine in aspartame may worsen uncontrolled muscle movements caused by TD. SIDE EFFECTS
  10. 10. When it comes to diabetes and weight loss, one of the first steps many people take is to reduce empty calories from their diets. This often includes sugar. Aspartame has both pros and cons when considering diabetes and obesity. According to a 2014 PLoS One study, rats who were fed aspartame had lower body masses overall. One caveat to the results was that these same rats also had more gut bacteria, as well as increased blood sugar. This increase in blood glucose was also linked to insulin resistance. DIABETES AND WEIGHT LOSS
  11. 11. Natural Alternatives to Aspartame • honey • maple syrup • agave nectar • fruit juice • molasses
  12. 12. Outlook Public concern over aspartame remains alive and well today. Some studies (as well as the FDA) have confirmed its safety, thereby leading to acceptance for everyday use. Due to heavy criticism, many people have taken steps to avoid artificial sweeteners altogether. Still, the consumption of aspartame by people conscious about their sugar intake continues to soar.
  13. 13. REFERENCES • http://www.healthline.com/health/aspartame-side-effects#Alternatives6 • https://en.wikipedia.org/wiki/Aspartame • http://www.sweetpoison.com/aspartame-side-effects.html