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The Technology of
Self-Tracking
From the Microbiome to Continuous
Glucose Monitoring
@sprague
Richard Sprague
Microbiome
#science
#science
Curiosity
Way of Thinking
Skepticism
LessWrongExperimentation
http://betabeat.com/2014/04/seth-roberts-final-column-butter-makes-me-
smarter/
Learning from Brain Reaction Time
Worse
Better
BrainReaction Time test is remarkablystable
Worse
Better
0 - 6 6 - 7 7 - 8 8 - 9
0 - 2 16 62 84 34
2 - 6 0 1 0 2
6 - 10 0 9 5 2
10 - 15 1 4 3 4
Z (hrs)
mg Welch Two Sample t-test
t = -1.1048, df = 34.861, p-value = 0.2768
95 percent confidence interval: -0.85 … 0.25
sample estimates
mean of x: 6.93
mean of y: 7.23
N = 32 (CBD)
N = 172 (no CBD)
No Effect
on Sleep
Microbes are everywhere
The vast majority of the DNA in and on your body comes from microbes, most of them co-
evolved with humans and much older than we are.
You can test your microbiome
sprague@personalscience.com
Blue line represents days on which I drank kombucha (3+ bottles/day)
GT’s drinksadd the patented Bacillus coagulans GBI-30,6086,
Kombuchadoesn’t domuch
Probiotic supplements: undetectable
Microbiome and Diet
Tily, et al. Gut microbiome activity
contributes to individual variation in
glycemic response in adults
Zeevi, D., Korem, T., Zmora, N., Israeli, D., Rothschild, D., Weinberger, A., … Segal, E. (2015).
Personalized Nutrition by Prediction of Glycemic Responses. Cell, 163(5), 1079–1094.
https://doi.org/10.1016/j.cell.2015.11.001
That’s not a
needle. It’s a
filament
sprague@personalscience.com
sprague@personalscience.com
sprague@personalscience.com
sprague@personalscience.com
Sprague@personalscience.com 28
sprague@personalscience.com
Sleep
#science
Make
Personal
Workshop
Friday 2-3pm
Room 6
Thank you
@sprague
https://personalscience.com/
https://medium.com/microbiome
https://richardsprague.com

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The Technology of Self-Tracking: From the Microbiome to Continuous Glucose Monitoring

Notas do Editor

  1. We live in a Golden Age for personal science: New, lost-cost technology makes it much easier for all of us to be scientists.
  2. The first meaning – I think the most common one – is a sense of wonder about the world.
  3. Another meaning – very common as well – associates science with technology. “Cool stuff people have been able to do”
  4. Here are the results from his classic self-experiment.  He found that he had better results on this test on days after he had eaten half a stick of butter.  He was pretty sure of the results, having tested it many times over many years. He even got a bunch of you (working with Genomera) to crowdsource a bigger test.
  5. Imagine my surprise when, analyzing the data later, I found this. red lines are with fish oil; blue lines without [higher is better]
  6. Here’s the most popular wearable. Maybe you use it to track your activity – and there are many interesting things you can learn if you just use the built-in apps. But what else is there?
  7. http://darwinian-medicine.com/wp-content/uploads/2015/01/human_ecosystem.jpg https://68.media.tumblr.com/243136221766e8fd6c6d357ff0ce0fe8/tumblr_o0fx6nYXph1qio57co1_1280.jpg Also see: https://www.differencebetween.com/wp-content/uploads/2017/06/Difference-Between-Microbiome-and-Microbiota-1.jpg
  8. I’m a little bit crazy…I’ve tested myself quite a bit. Since 2014 I’ve been testing my microbiome a lot – almost daily.
  9. https://www.biorxiv.org/content/10.1101/641019v2
  10. https://www.nissinfoods.com/products/top-ramen-noodles