4. Bastian, H., Glasziou, P., & Chalmers, I. (2010). Seventy-five trials and eleven systematic reviews a day: How will we ever keep up? PLoS Medicine, 7 (9), 1-11. Policy and academic milestones in the development of trials and the science of reviewing trials.

5. The number of systematic reviews in health care, 1990 to 2007. Bastian, H., Glasziou, P., & Chalmers, I. (2010). Seventy-five trials and eleven systematic reviews a day: How will we ever keep up? PLoS Medicine, 7 (9), 1-11.

6. Evidence at Becker : Systematic Reviews

7. Reproducibility A systematic review is just like any other kind of research which means that an independent party can read your lab notes, execute the same actions, and return the same results. If you keep this in mind from the beginning, you will have a much easier time later in the process, when you are writing the article for publication, and when you update the review in the future. Start Out Right, Stay Organized

11. Type of Study Type of Question Ideal Type of Study Therapy RCT Prevention RCT > Cohort > Case Control Diagnosis Prospective, blind controlled comparison to gold standard Prognosis Cohort > Case Control > Case Series/Case Report Etiology/Harm RCT > Cohort > Case Control

12. How questions influence search results Robin Featherstone. (2010). Literature reviews for the health sciences Relevancy Retrieval (# of search results) Broad Questions Narrow Questions High = lots of articles Low = very few articles High = directly relevant articles Low = mostly irrelevant articles

18. Questions?