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PULMONARY FUNCTION TEST
Rahul AP.
Asst Proff, LIAHS
BPT,MPT MIAP
CRD&ICU Care
PFT
• Pulmonary function tests (PFTs) are a group of tests
that measure how well your lungs works, how well
the lungs take in and exhale air, and how efficiently
they transfer oxygen into the blood
• PFT or LFT are useful in assessing the functional
status of the respiratory system both in
physiological and pathological condition
• It is base on the measurement of volumes of air
breathed in and out in normal breathing and forced
breathing
• It is carried out by using a spirometer
Lung volume and capacities
• Lung vol: are the static vol: of air breathed by
an individual, ie vol: of air present in lung
under specific position of the torax
• 4 lung volumes
• Depends on age, weight, gender and body
position
• 2 or more vol: when combined are capacity
Lung volumes
• TV-the vol: of gas exchanged during a relaxed insp:
followed by an exp: 500ml
• IRV-extra vol: of gas that can be inspired above
tidal insp: 3000ml
• ERV-extra vol: of gas that can be expired after a
normal tidal exp: 1000ml
• RV-vol: of gas remain in lungs after a forceful exp:
1500ml
• IC-max: amount of gas inspired in to the lungs after a
normal tidal exp: [IC=TV+IRV] 3500ml
• FRC-amount of gas remain in the lungs after normal
exp:[ FRC=ERV+RV] 2500ml
• VC-max: amount of gas expired from the lungs after a
max: insp: [VC=IRV+TV+ ERV] 4500ml
• TLC-max: amount of gas inspired to expand the lungs to
its max:extend [TLC=TV+IRV +ERV +RV] 6000ml
Lung capacity
Graph
Mechanics of Breathing
• Inspiration
Active process
• Expiration
Quiet breathing: passive
Can become active
Pulmonary Function Tests Evaluates 1 or more
major aspects of the respiratory system
• Lung volumes
• Airway function
• Gas exchange
Indications/purpose
• Detect disease, It serve as a diagnostic tool
investigation role
• Evaluate severity, extent and monitor the course of
disease
• Evaluate treatment
• Measure effects and result of treatment exposures
PFTs can help diagnose
• Asthma
• Chronic bronchitis
• Respiratory infections
• Lung fibrosis
• Bronchiectasis
• Allergy
• Emphysema
• Cystic fibrosis
• Asbestosis which is a condition caused by exposure
to asbestos
• Sarcoidosis, which is an inflammation of your lungs,
liver, lymph nodes, eyes, skin, or other tissues
• Pulmonary tumor
Spirometry
• It is an instrument for measuring the air capacity of
the lungs
• Measurement of the pattern of air movement in
and out of the lungs during controlled ventilatory
maneuvers.
• spirometre is used to measure the air flow,
ventilatory regulation, ventilatory mechanics and
lung volume during a forced expiratory maneuver
from full inspiration.
• Pft used to evaluate physiological aspect of
breathing from resp:muscle function to the
diffusion of gas at the alviolar wall.
• Pft helps physiotherapist to distinguish between
obstructive and restrictive lung problem and to
select appropriate treatment
• It also measure the effect of the given treatment.
Lung Factors Affecting Spirometry
• Mechanical properties
• Resistive elements
Mechanical Properties
• Compliance
–Describes the stiffness of the lungs
–Change in volume over the change in
pressure
• Elastic recoil
–The tendency of the lung to return to it’s
resting state
–A lung that is fully stretched has more
elastic recoil and thus larger/ maximal flows
of gas
Resistive Properties
Affected by:
Lung volume
Age
Sex
Height
Weight
Race
Disease
Bronchial smooth muscles
PFT procedure
• Forced expiratory maneuver is the common clinical
approach
• Results are found in patients chart/moniter
• Common spirometric values areFEV1 and FVC
FEV1/FVC ratio
• Lung volume and peak expiratory flow rate (PEF or
PEFR) are measured to differentiate obstructive or
restrictive problems
• Forced expiratory flow (FEF)
• Sit up straight
• Get a good seal around the mouth piece
• Rapid inhale maximally
• Without any delay blow out as hard as fast as
possible (blast out)
• Continue the exhale until the patient can`t
blow no more
• Expiration should continue at least 6sec (in
adult) and 3 sec (children under 10yrs)
• Repeat at least 3 technically acceptable times
(without cough, air leak and false start)
Procedure
Normal spirogram
How to interpret abnormal PFT
• If FVC&FEV1 is less than 80% (total vol:of air
expelling is approx: 80% with in 1sec ie; FEV1)
• Suggestions of some pathology, at this point
and can`t decide obstructive/ restrictive
problem
Forced expiratory volume in 1 second
(FEV1)
• FEV1 is the volume of air that can forcibly be blown
out in one second, after full inspiration.
• Average values for FEV1 in healthy people depend
mainly on sex and age height and mass.
• Values between 80% and 120% are considered
normal.
Forced vital capacity (FVC)
• Forced vital capacity(FVC) is the volume of air
that can forcibly be blown out after full
inspiration
FEV1/FVC ratio (FEV1%)
• FEV1/FVC (FEV1%) is the ratio of FEV1 to FVC.
In healthy adults this should be approximately
75–80%.
Forced expiratory flow (FEF)
• Forced expiratory flow (FEF) is the flow (or speed)
of air coming out of the lung during the middle
portion of a forced expiration.
• generally defined by fraction, The usual intervals
are 25%, 50% and 75% (FEF25, FEF50 and FEF75)
Identify an obstructive problem
• Obst: disorders (asthma, copd) air flow
reduces because of narrowing of air ways
• FEV1 is reduced
• Spirogram is continued to 6 sec to empty lung,
FVC also reduced because gas is trapped
behind the obstructed bronchi
• Cardinal feature of obstructive defect is
reduction in the FEV1/FVC ratio
• In obstructive diseases (asthma, COPD, chronic
bronchitis, emphysema) FEV1 is diminished because
of increased airway resistance to expiratory flow.
• The FVC may be decreased due to the premature
closure of airway in expiration
• This generates a reduced value (<80%, often 45%).
60-80% -mild
40-60% -moderate
<40% -severe obstructions
Obstructive spirogram
Obstructive Disorders
Restrictive problem
• Restrictive disorders can be cause by disease of the
lung parenchyma (lung fibrosis) and chest wall
disease(kyphoscoliosis)
• This prevent the full expansion of the lungs
therefore FVC may be reduced
• FEV1 will increased because of the stiffness of the
fibrotic lungs increases the expiratory pressure
• Hence expired air comes out very quickly resulting
with a high FEV1/FVC ratio
Restrictive spirogram
Restrictive Lung Disease
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Pulmonary Function Test

  • 1. PULMONARY FUNCTION TEST Rahul AP. Asst Proff, LIAHS BPT,MPT MIAP CRD&ICU Care
  • 2. PFT • Pulmonary function tests (PFTs) are a group of tests that measure how well your lungs works, how well the lungs take in and exhale air, and how efficiently they transfer oxygen into the blood
  • 3. • PFT or LFT are useful in assessing the functional status of the respiratory system both in physiological and pathological condition • It is base on the measurement of volumes of air breathed in and out in normal breathing and forced breathing • It is carried out by using a spirometer
  • 4.
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  • 6. Lung volume and capacities • Lung vol: are the static vol: of air breathed by an individual, ie vol: of air present in lung under specific position of the torax • 4 lung volumes • Depends on age, weight, gender and body position • 2 or more vol: when combined are capacity
  • 7. Lung volumes • TV-the vol: of gas exchanged during a relaxed insp: followed by an exp: 500ml • IRV-extra vol: of gas that can be inspired above tidal insp: 3000ml • ERV-extra vol: of gas that can be expired after a normal tidal exp: 1000ml • RV-vol: of gas remain in lungs after a forceful exp: 1500ml
  • 8. • IC-max: amount of gas inspired in to the lungs after a normal tidal exp: [IC=TV+IRV] 3500ml • FRC-amount of gas remain in the lungs after normal exp:[ FRC=ERV+RV] 2500ml • VC-max: amount of gas expired from the lungs after a max: insp: [VC=IRV+TV+ ERV] 4500ml • TLC-max: amount of gas inspired to expand the lungs to its max:extend [TLC=TV+IRV +ERV +RV] 6000ml Lung capacity
  • 10. Mechanics of Breathing • Inspiration Active process • Expiration Quiet breathing: passive Can become active Pulmonary Function Tests Evaluates 1 or more major aspects of the respiratory system • Lung volumes • Airway function • Gas exchange
  • 11. Indications/purpose • Detect disease, It serve as a diagnostic tool investigation role • Evaluate severity, extent and monitor the course of disease • Evaluate treatment • Measure effects and result of treatment exposures
  • 12. PFTs can help diagnose • Asthma • Chronic bronchitis • Respiratory infections • Lung fibrosis • Bronchiectasis • Allergy
  • 13. • Emphysema • Cystic fibrosis • Asbestosis which is a condition caused by exposure to asbestos • Sarcoidosis, which is an inflammation of your lungs, liver, lymph nodes, eyes, skin, or other tissues • Pulmonary tumor
  • 14. Spirometry • It is an instrument for measuring the air capacity of the lungs • Measurement of the pattern of air movement in and out of the lungs during controlled ventilatory maneuvers. • spirometre is used to measure the air flow, ventilatory regulation, ventilatory mechanics and lung volume during a forced expiratory maneuver from full inspiration.
  • 15.
  • 16. • Pft used to evaluate physiological aspect of breathing from resp:muscle function to the diffusion of gas at the alviolar wall. • Pft helps physiotherapist to distinguish between obstructive and restrictive lung problem and to select appropriate treatment • It also measure the effect of the given treatment.
  • 17. Lung Factors Affecting Spirometry • Mechanical properties • Resistive elements
  • 18. Mechanical Properties • Compliance –Describes the stiffness of the lungs –Change in volume over the change in pressure • Elastic recoil –The tendency of the lung to return to it’s resting state –A lung that is fully stretched has more elastic recoil and thus larger/ maximal flows of gas
  • 19. Resistive Properties Affected by: Lung volume Age Sex Height Weight Race Disease Bronchial smooth muscles
  • 20. PFT procedure • Forced expiratory maneuver is the common clinical approach • Results are found in patients chart/moniter • Common spirometric values areFEV1 and FVC FEV1/FVC ratio • Lung volume and peak expiratory flow rate (PEF or PEFR) are measured to differentiate obstructive or restrictive problems • Forced expiratory flow (FEF)
  • 21. • Sit up straight • Get a good seal around the mouth piece • Rapid inhale maximally • Without any delay blow out as hard as fast as possible (blast out) • Continue the exhale until the patient can`t blow no more • Expiration should continue at least 6sec (in adult) and 3 sec (children under 10yrs) • Repeat at least 3 technically acceptable times (without cough, air leak and false start) Procedure
  • 23. How to interpret abnormal PFT • If FVC&FEV1 is less than 80% (total vol:of air expelling is approx: 80% with in 1sec ie; FEV1) • Suggestions of some pathology, at this point and can`t decide obstructive/ restrictive problem
  • 24. Forced expiratory volume in 1 second (FEV1) • FEV1 is the volume of air that can forcibly be blown out in one second, after full inspiration. • Average values for FEV1 in healthy people depend mainly on sex and age height and mass. • Values between 80% and 120% are considered normal.
  • 25. Forced vital capacity (FVC) • Forced vital capacity(FVC) is the volume of air that can forcibly be blown out after full inspiration
  • 26. FEV1/FVC ratio (FEV1%) • FEV1/FVC (FEV1%) is the ratio of FEV1 to FVC. In healthy adults this should be approximately 75–80%.
  • 27. Forced expiratory flow (FEF) • Forced expiratory flow (FEF) is the flow (or speed) of air coming out of the lung during the middle portion of a forced expiration. • generally defined by fraction, The usual intervals are 25%, 50% and 75% (FEF25, FEF50 and FEF75)
  • 28. Identify an obstructive problem • Obst: disorders (asthma, copd) air flow reduces because of narrowing of air ways • FEV1 is reduced • Spirogram is continued to 6 sec to empty lung, FVC also reduced because gas is trapped behind the obstructed bronchi • Cardinal feature of obstructive defect is reduction in the FEV1/FVC ratio
  • 29. • In obstructive diseases (asthma, COPD, chronic bronchitis, emphysema) FEV1 is diminished because of increased airway resistance to expiratory flow. • The FVC may be decreased due to the premature closure of airway in expiration • This generates a reduced value (<80%, often 45%). 60-80% -mild 40-60% -moderate <40% -severe obstructions
  • 32. Restrictive problem • Restrictive disorders can be cause by disease of the lung parenchyma (lung fibrosis) and chest wall disease(kyphoscoliosis) • This prevent the full expansion of the lungs therefore FVC may be reduced • FEV1 will increased because of the stiffness of the fibrotic lungs increases the expiratory pressure • Hence expired air comes out very quickly resulting with a high FEV1/FVC ratio