The document discusses how the Chicago Department of Public Health is innovating public health practices through three pillars: informatics, application development, and predictive analytics. It provides examples of projects within each pillar, such as developing an informatics tool to provide community health profiles to providers, creating a referral system to directly connect patients to tobacco cessation support, and developing the Chicago Health Atlas website through partnerships. The department aims to improve resource use, engage citizens, and spur economic development through these innovative approaches using data.