http://www.depuypinnaclelawsuit.com/ Very alarming is the surge of the number of cancer patients among children with juvenile arthritis, medicinenet.com says.

1. As published on the DePuy Pinnacle Lawsuit
website

2. Very alarming is the surge of the
number of cancer patients among
children with juvenile arthritis,
medicinenet.com says.
Conversely, there is an internal
email in 2009 which defines the
Food and Drug Administration's
(FDA) ‘non-approval’ letter for
DePuy Hip.
The news also said that the
cancer ratio among children with
juvenile arthritis is four times
greater than in other children.

3. Arthritis in children is like those in adults. Arthritis is caused by
the inflammation of the joints. It may result to pain, swelling,
stiffness, and loss of motion, as mentioned in the National
Institute of Arthritis and Musculoskeletal and Skin Diseases. An
estimated of 294,000 American children were affected with
Juvenile arthritis ranging from ages 18 and below who belong to
various ethnic backgrounds.
Doctors who treat arthritis in children will try to make sure that
your child can remain physically active. They will also see to it
that your child remains involved in social activities and possess a
total worthy quality of life. Doctors may propose usages to ease
swelling, maintain joint movement, and relieve pain. They also
try to prevent, identify and treat problems that result from the
arthritis, the National Institute of Arthritis and Musculoskeletal
and Skin Diseases website says.

4. This alarming risk of developing cancer is not necessarily
related to arthritis treatments, such as tumor necrosis factor
(TNF) inhibitors, as mentioned in the study published in the
journal of Arthritis & Rheumatism, drugs.com reported. In
America, TNF inhibitors has a "black box" warning about the
possible cancer risk linked with the drugs. In this research, the
researchers analyzed Medicaid data from 2000-2005 of more
than 7,800 children with juvenile arthritis and comparison
groups of about 650,000 children with asthma and nearly
322,000 children with attention-deficit hyperactivity disorder
(ADHD), as stated in drugs.com. The occurrence rate of feasible
and highly probable cancers in children with juvenile arthritis
was 4.4 times higher than in the other groups of children.
Juvenile idiopathic arthritis (JIA) in children is a general term
covering dissimilar types of chronic arthritis.

5. Symptoms, similar to adult arthritis, include joint pain, swelling,
tenderness and stiffness, drugs.com says. "While our findings
show children with [juvenile idiopathic arthritis] have a higher
incidence of cancer compared to peers without JIA, the greater
frequency of malignancy does not appear to be necessarily
associated with treatment, including use of TNF inhibitors,"
concluded Dr. Timothy Beukelman, of the University of Alabama
at Birmingham, in a journal news release.
Beukelman mentioned that this places a critical importance of
appropriate comparator groups when evaluating the safety of
new medications. Further endorsement of the findings with
large-scale and long-term investigation of the association
between cancer and juvenile arthritis with its treatment is
needed.

6. Usually arthritis may lead to surgery among adults such as hip
replacement which triggers Pinnacle Lawsuit.
THE END