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Intestinal Gas:
        Charting the course through a
               perilous miasma

            Patricia L Raymond MD FACP FACG
                          Rx for Sanity, Chesapeake VA
                            24 January 2009 1125-1215
Debbie Waiz 15th Annual           RxForSanity.com
 Endoscopy Symposium            ColonoscopyJoke.com
“If you jog in a jogging suit,
       lounge in lounging pajamas,
      and smoke in a smoking jacket,

           WHY would anyone want to
            wear a windbreaker??"


Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Farts are fun!




Debbie Waiz 15th Annual        RxForSanity.com
 Endoscopy Symposium         ColonoscopyJoke.com
Other terms for
                               Gas
   Poof/poot
   Fluff                               My favorites:
   Cut the cheese
                                         Air biscuit
   Launch a loaf
   Rhino stopper                        Trouser cough
   Shot a bunny                         Bottom burp


Debbie Waiz 15th Annual        RxForSanity.com
 Endoscopy Symposium         ColonoscopyJoke.com
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
The manly art of fart-burning.
  Compression, ignition, combustion
      and exhaust. ~Frank Zappa

 Methane burns in oxygen forming water
  and carbon dioxide often producing a blue
  hue
     CH4 + 2O2 → CO2 + 2H2O
 Hydrogen sulfide also combusts
    2H2S + 3O2 → 2SO2 + 2H2O
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
How long would you need to
     continuously pass flatus in
     order to generate methane
     gas with the energy of an
     atomic bomb?

            6 years and 9 months
            12 years and 3 months
            25 years
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Flatulence in
          America’s War on Terrorism




Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Measurement of Gas




Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Measurement of Gas
 Techniques include plethmography, argon
  washout technique, digitized KUB
 Average amount only 200 ml,
  range 115 ml to 1000 ml
 14-23 average passage per day
  (flatus + eructation)



Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Composition of gas
                                      99% nitrogen, oxygen,
                                       carbon dioxide,
                                       hydrogen, methane
                                      Location, location,
                                       location
                                          – Stomach: high nitrogen,
                                            oxygen (similar to
                                            atmosphere)
                                          – Colon: less oxygen,
                                            more methane
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Odor of gas


 Minor constituents (1%)
 Sulfur containing compounds, SCFA,
  volatile amines, ammonia
 Generally attributed to bacterial metabolism



Debbie Waiz 15th Annual       RxForSanity.com
 Endoscopy Symposium        ColonoscopyJoke.com
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Sources of gas
                                        Aerophagia
                                         Rapid eating/drinking
                                         Chewing gum
                                         Carbonated beverages
                                         Smoking or drinking
                                          through straw
                                         Poor fitting dentures
                                         Nervous habit

Debbie Waiz 15th Annual        RxForSanity.com
 Endoscopy Symposium         ColonoscopyJoke.com
Intraluminal production
                                      CO2: from digestion fat,
                                       protein in upper SB,
                                       bacterial fermentation of
                                       malabsorbed foods, or
                                       acid + bicarb
                                      H2: mainly from colon,
                                       may result from small
                                       bowel bacterial overgrowth
                                       (bacterial fermentation)
                                      CH4: only from bacterial
                                       metabolism
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Instilled or iatrogenic gas




Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Sounds of intestinal gas
                                      Joseph Pujol, 19th
                                       century France
                                      Vibration of anal orifice
                                      Variations
                                          – Tightness of sphincter
                                            muscle
                                          – Velocity of gas
                                          – Other (TMI) moisture,
                                            body fat

Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Petomaine persists today
                                      Italian movie 'Il Petomane',
                                       contrasting his deep
                                       longing for normalcy with
                                       the condition of 'freak' to
                                       which his act relegated
                                       him.
                                      Blazing Saddles (1974)
                                       Mel Brooks plays the part
                                       of "Governor William J. Le
                                       Petomane".
                                      Johnny Depp has
                                       mentioned frequently in
                                       interviews that he wishes
                                       to portray Pujol in a film.
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Fart In A Jar Sells for $71 on eBay

                                      In 2007 a fart in a jar
                                       from a "hot girl" sold
                                       for $71 on eBay.
                                      It had 24 bids




Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Diamonds are forever?
 Janine Roberts' new book
             "Glitter &
  Greed: The Secret World
  of the Diamond Cartel"
  exposes the unromantic
  side of diamonds.
    – Roberts has seen scientists
      "grow diamonds" using
      methane and oxygen which
      she says means diamonds
      are nothing more than
       "crystallized farts."
Debbie Waiz 15th Annual      RxForSanity.com
 Endoscopy Symposium       ColonoscopyJoke.com
Intestinal Gas: Sounds
 Borborigmi
 Term for noises
  generated as gas &
  fluid travel through the
  gut
 A normal sound when
  rumbling/low, although
  high pitched suggests
  PSBO

Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Herring Break Wind to
      Communicate, Study Suggests
 Ben Wilson, a marine biologist at the
  Bamfield Marine Science Centre, British
  Columbia, Canada U.K. science journal
  Biology Letters, 2003
 Atlantic and Pacific herring
 Fast Repetitive Tick (FRT): high-frequency
  nocturnal sound bursts up to 22 kilohertz,
  accompanied by a fine stream of bubbles
  from the anus.
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Foods that cause gas: Sugars
                                      Raffinose
                                          – Beans
                                          – Smaller amounts in
                                            cruciferous vegs and grains
                                      Lactose
                                          – Milk products & processed
                                            foods
                                          – Asian, AA, Native American
                                          – Lactase drops with aging
                                      Fructose
                                          – Also soft drinks, onions,
                                            artichokes, wheat
                                      Sorbitol
                                          – Fruits, dietetic foods, sugar
                                            free foods, gum
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Gassy foods round-up
      provided as a pre-lunch service by PLR
 Beyond the beans…
 Peas, lentils, soybeans
 Broccoli, cabbage, cauliflower, cucumber,
  green pepper, kolrabi, brussels sprouts,
  onions, leeks, artichokes, and asparagus
 Pears, apples, avocados, bananas, melon
  and peaches , prunes and raisins
 Whole grains, such as whole wheat and
  bran.
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Starches, fiber & gas
 Most starches produce gas
  with breakdown in colon
  (except rice)
    – Potatoes, corn, pasta
 Fiber
    – Soluble fiber (dissolves in
      H2O to gel) in oat bran,
      fruits, beans, not broken
      down until reaches colon.
          digestion by bacteria
           causes gas
    – Insoluble fiber (wheat bran,
      some vegs) passes
      unchanged through bowel &
      causes no gas
Debbie Waiz 15th Annual          RxForSanity.com
 Endoscopy Symposium           ColonoscopyJoke.com
Halloween Fun?




Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
What to do about intestinal gas?




Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
If predominantly eructation
                                     Think about:
                                      GERD
                                      Gastroparesis
                                          – Gastric emptying study
                                      Dietary Aerophagia
                                      Habit/learned behavior
                                          – Responds well to
                                            biofeedback and
                                            antidepressant therapy

Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Abdominal distension & bloat
Think about:
 Nissan fundoplication
   – 10% ‘gas-bloat’ syndrome
 Irritable bowel syndrome
   – Positive ‘panty sign’
 Consider PSBO
   – Small bowel enteroclysis
 Dietary, bacterial overgrowth
    – LTT to determine role of
      intolerance (not Y or N)
    – > 30 mg/dl within 2 hours normal. 20-30
      mg/dl inconclusive. < 20 mg/dl abnormal.
Debbie Waiz 15th Annual         RxForSanity.com
 Endoscopy Symposium          ColonoscopyJoke.com
Predominant flatulence
                                      Food diary
                                      Celiac testing (TTG-
                                       IgA & total IgA)
                                      Trial digestive
                                       enzymes (beano,
                                       lactaid, prelief)
                                      Hydrogen breath
                                       testing (SBO?)
                                      Education (NIDDK)
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
ColicInfant.com




Debbie Waiz 15th Annual         RxForSanity.com
 Endoscopy Symposium          ColonoscopyJoke.com
Empiric therapy
 Simethicone not very effective
  (Phazyme, Mylicon, Gas-X, Mylanta
  Gas)
    – Changes the surface tension of gas
      bubbles, enabling smaller bubbles to
      join together into bigger bubbles.
 Charcoal
    – Tablets, briefs or pads
    – May absorb other medications
    – Theoretically adsorbs gas volume
 Bismuth
    – Said to reduce odor of HS gas
 Probiotic therapy/antibiotic therapy
    – Replace/reduce gas producing bacteria



Debbie Waiz 15th Annual         RxForSanity.com
 Endoscopy Symposium          ColonoscopyJoke.com
Never pass gas in a wetsuit.
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Thanks for letting me get this
                   presentation out of my system…

                          “Better out than in,
                            I always say.”
                           ~Shrek (Mike Myers)




Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com
Questions?




Debbie Waiz 15th Annual      RxForSanity.com
 Endoscopy Symposium       ColonoscopyJoke.com
Have a 239 bean day!
             Anything more would be ‘too farty’
                          (240)!

             ~From a SGNA colleague who shall remain nameless


Debbie Waiz 15th Annual       RxForSanity.com
 Endoscopy Symposium        ColonoscopyJoke.com
Debbie Waiz 15th Annual     RxForSanity.com
 Endoscopy Symposium      ColonoscopyJoke.com

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Intestinal gas raymond

  • 1. Intestinal Gas: Charting the course through a perilous miasma Patricia L Raymond MD FACP FACG Rx for Sanity, Chesapeake VA 24 January 2009 1125-1215 Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 2. “If you jog in a jogging suit, lounge in lounging pajamas, and smoke in a smoking jacket, WHY would anyone want to wear a windbreaker??" Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 3. Farts are fun! Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 4. Other terms for Gas  Poof/poot  Fluff My favorites:  Cut the cheese  Air biscuit  Launch a loaf  Rhino stopper  Trouser cough  Shot a bunny  Bottom burp Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 5. Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 6. The manly art of fart-burning. Compression, ignition, combustion and exhaust. ~Frank Zappa  Methane burns in oxygen forming water and carbon dioxide often producing a blue hue CH4 + 2O2 → CO2 + 2H2O  Hydrogen sulfide also combusts 2H2S + 3O2 → 2SO2 + 2H2O Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 7. How long would you need to continuously pass flatus in order to generate methane gas with the energy of an atomic bomb? 6 years and 9 months 12 years and 3 months 25 years Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 8. Flatulence in America’s War on Terrorism Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 9. Measurement of Gas Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 10. Measurement of Gas  Techniques include plethmography, argon washout technique, digitized KUB  Average amount only 200 ml, range 115 ml to 1000 ml  14-23 average passage per day (flatus + eructation) Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 11. Composition of gas  99% nitrogen, oxygen, carbon dioxide, hydrogen, methane  Location, location, location – Stomach: high nitrogen, oxygen (similar to atmosphere) – Colon: less oxygen, more methane Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 12. Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 13. Odor of gas  Minor constituents (1%)  Sulfur containing compounds, SCFA, volatile amines, ammonia  Generally attributed to bacterial metabolism Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 14. Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 15. Sources of gas Aerophagia  Rapid eating/drinking  Chewing gum  Carbonated beverages  Smoking or drinking through straw  Poor fitting dentures  Nervous habit Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 16. Intraluminal production  CO2: from digestion fat, protein in upper SB, bacterial fermentation of malabsorbed foods, or acid + bicarb  H2: mainly from colon, may result from small bowel bacterial overgrowth (bacterial fermentation)  CH4: only from bacterial metabolism Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 17. Instilled or iatrogenic gas Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 18. Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 19. Sounds of intestinal gas  Joseph Pujol, 19th century France  Vibration of anal orifice  Variations – Tightness of sphincter muscle – Velocity of gas – Other (TMI) moisture, body fat Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 20. Petomaine persists today  Italian movie 'Il Petomane', contrasting his deep longing for normalcy with the condition of 'freak' to which his act relegated him.  Blazing Saddles (1974) Mel Brooks plays the part of "Governor William J. Le Petomane".  Johnny Depp has mentioned frequently in interviews that he wishes to portray Pujol in a film. Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 21. Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 22. Fart In A Jar Sells for $71 on eBay  In 2007 a fart in a jar from a "hot girl" sold for $71 on eBay.  It had 24 bids Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 23. Diamonds are forever?  Janine Roberts' new book "Glitter & Greed: The Secret World of the Diamond Cartel" exposes the unromantic side of diamonds. – Roberts has seen scientists "grow diamonds" using methane and oxygen which she says means diamonds are nothing more than "crystallized farts." Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 24. Intestinal Gas: Sounds  Borborigmi  Term for noises generated as gas & fluid travel through the gut  A normal sound when rumbling/low, although high pitched suggests PSBO Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 25. Herring Break Wind to Communicate, Study Suggests  Ben Wilson, a marine biologist at the Bamfield Marine Science Centre, British Columbia, Canada U.K. science journal Biology Letters, 2003  Atlantic and Pacific herring  Fast Repetitive Tick (FRT): high-frequency nocturnal sound bursts up to 22 kilohertz, accompanied by a fine stream of bubbles from the anus. Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 26. Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 27. Foods that cause gas: Sugars  Raffinose – Beans – Smaller amounts in cruciferous vegs and grains  Lactose – Milk products & processed foods – Asian, AA, Native American – Lactase drops with aging  Fructose – Also soft drinks, onions, artichokes, wheat  Sorbitol – Fruits, dietetic foods, sugar free foods, gum Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 28. Gassy foods round-up provided as a pre-lunch service by PLR  Beyond the beans…  Peas, lentils, soybeans  Broccoli, cabbage, cauliflower, cucumber, green pepper, kolrabi, brussels sprouts, onions, leeks, artichokes, and asparagus  Pears, apples, avocados, bananas, melon and peaches , prunes and raisins  Whole grains, such as whole wheat and bran. Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 29. Starches, fiber & gas  Most starches produce gas with breakdown in colon (except rice) – Potatoes, corn, pasta  Fiber – Soluble fiber (dissolves in H2O to gel) in oat bran, fruits, beans, not broken down until reaches colon.  digestion by bacteria causes gas – Insoluble fiber (wheat bran, some vegs) passes unchanged through bowel & causes no gas Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 30. Halloween Fun? Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 31. What to do about intestinal gas? Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 32. Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 33. If predominantly eructation Think about:  GERD  Gastroparesis – Gastric emptying study  Dietary Aerophagia  Habit/learned behavior – Responds well to biofeedback and antidepressant therapy Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 34. Abdominal distension & bloat Think about:  Nissan fundoplication – 10% ‘gas-bloat’ syndrome  Irritable bowel syndrome – Positive ‘panty sign’  Consider PSBO – Small bowel enteroclysis  Dietary, bacterial overgrowth – LTT to determine role of intolerance (not Y or N) – > 30 mg/dl within 2 hours normal. 20-30 mg/dl inconclusive. < 20 mg/dl abnormal. Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 35. Predominant flatulence  Food diary  Celiac testing (TTG- IgA & total IgA)  Trial digestive enzymes (beano, lactaid, prelief)  Hydrogen breath testing (SBO?)  Education (NIDDK) Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 36. ColicInfant.com Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 37. Empiric therapy  Simethicone not very effective (Phazyme, Mylicon, Gas-X, Mylanta Gas) – Changes the surface tension of gas bubbles, enabling smaller bubbles to join together into bigger bubbles.  Charcoal – Tablets, briefs or pads – May absorb other medications – Theoretically adsorbs gas volume  Bismuth – Said to reduce odor of HS gas  Probiotic therapy/antibiotic therapy – Replace/reduce gas producing bacteria Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 38. Never pass gas in a wetsuit. Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 39. Thanks for letting me get this presentation out of my system… “Better out than in, I always say.” ~Shrek (Mike Myers) Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 40. Questions? Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 41. Have a 239 bean day! Anything more would be ‘too farty’ (240)! ~From a SGNA colleague who shall remain nameless Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com
  • 42. Debbie Waiz 15th Annual RxForSanity.com Endoscopy Symposium ColonoscopyJoke.com