2. Medical Applications of Nanotechnology Gholamreza Pourmand, M.D.

3. What is nano? Power Prefix Origins 10 12 tera teras: monster 10 9 giga gigas: giant 10 6 mega megas: large 10 3 kilo chilioi: thousand 10 -3 milli milli: thousand 10 -6 micro mikros: small 10 -9 nano nanos: dwarf

5. Nanotechnology Growth S. Milunovich, J. Roy. United States Technology Strategy. Merrill Lynch. 4 Sept. 2001

6. How small is nano? Scale: Nanoscale $151,700: 1/100 th cent Acre: 1/100 th square inch Decade: 1/3 rd second E. Corcoran. The Next Small Thing. Forbes Magazine , 07/23/01

8. Many Different Length Scales 10cm 1cm 100  m 1  m

9. Relative Size of Nanoparticles Nanoparticle with a 2 nm core and an octanethiol functionalized monolayer

25. Smart Nanostructures for Selective Drug Delivery Scale: 1/40 th of red blood cell Nanotube Nanocap Drug Delivery for: #1 - Cardiovascular disease #2 – Cancer #3 - Infectious diseases Toxin Removal for: Adverse drug reactions >106,000 deaths/yr Pesticide Poisonings >220,000 deaths/yr

26. Targeted Delivery to Tumors