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OVERVIEW
                                                    1. Definition of ‘primary care’
         INTEGRATIVE MEDICINE
                                                                                y
                                                    2. Healthcare 2014 and beyond
             Eric J. Deppert, MD, FACP              3. A day in the life of …………. Me
        Clinical Assistant Professor of Medicine,   4. Evidence based pharmacopoeia & herbal
                                                    4 E id       b d h              i    h b l
         Drexel University College of Medicine         treatment
               Postprofessional Faculty,            5. Role of CAM & integrative practices in the future
         National University of Health Sciences
                           y                           of healthcare
                                                    6. MS ACP program and NUHS rewriting the book




             Primary Prevention                              Secondary Prevention
•   Protect against disease and disability          • Identify and detect disease at its earliest
                                                       d    f    dd       d                 l
•   Immunizations                                     stage, before noticeable
                                                    • Prevent the spread of communicable diseases
•   Safe drinking water
                                                    • BP screening
•   Seatbelts and airbags
                                                    • Colorectal screening
•   Health promotion & wellness                     • IFG/DM & lipids
                                                          /
    – Stress management
                                                    • Pap smear
                                                         p
    – Parenting classes
                                                    • PSA
    – Cooking classes
                                                                                                           1
Tertiary Prevention                                                       Healthcare 2014 and Beyond
• Locking the barn after the horse is out                                               •   50,000,000 i
                                                                                            50 000 000 uninsured d
                                                                                        •   30,000,000 covered (Affordable Care Act)
• 95% of my world
                                                                                        •   20,000,000 left out?
                                                                                        •   “Cost containment” Chiro opportunity
                                                                                        •   Rationing of health care (Arizona MA xplants)
                                                                                        •   Evidence based medicine
                                                                                        •   My experience before Affordable Care Act
                                                                                        •   CASE: Betsy Headache
                                                                                                      y
                                                                                             – MRA dissection
                                                                                             – Couldn’t get approved




                                                                                             Accreditation Council for
                                Education
                                                                                        Graduate Medical Education (ACGME)
• Bachelor of Science (BS) degree (4 years)                                                 Responsible for the accreditation of post MD medical training
• Doctor of Medicine (MD) degree (4 years)                                              Core Competencies
     – Years 1 & 2: Basic & Clinical Sciences (classroom)
     – Years 3 & 4: Clinical Rotations / Clerkships                                     •   Patient care
                                                                                        •
     Average GPA entering program 3.80/4.00*
• Postgraduate Residency (3+ years)                                                         Medical knowledge
     –
     –
         PGY
         PGY
               1
               2
                   Internship
                   Resident (Internal Medicine)                                         •   Practice based learning & improvement
     –
     –
         PGY
         PGY
               3
               4
                   Resident (Internal Medicine)
                   Chief Medical Resident (Internal Medicine)                           •   Systems based practice
• USMLE Parts 1, 2, Clinical Skills, 3                                                  •   Interpersonal skills and communication
• A
  American Board of I t
      i    B d f Internal M di i C tifi ti E
                              l Medicine Certification Exam
     – Recertification (every 10 years)                                                 •   Professionalism
•   Upon successful completion of the residency program, one is able to practice
    medicine independently (pursue licensure) and sit for certification examinations.

                                                                                                                                                            2
Medical Professionalism in the
                        Positions Held
                                                                               New Millennium
• Clinical Assistant, Chairman of Education
           Assistant                                             • A physician charter: professionalism i th b i of
                                                                      h i i      h t         f i    li is the basis f
  (Presbyterian/UPenn)                                             medicine’s contract with society.
• Director of Ambulatory Care
                       y                                         • Principle of Primacy of Patient Welfare
                                                                                                   Welfare.
  (Presbyterian/UPenn)
                                                                 • Principle of Patient Autonomy.
• Director Podiatric Medical Consults
  (Presbyterian/UPenn)                                           • Principle of Social Justice.
• Internal Medicine Residency Director (Presbyterian/UPenn and   • Commitment to Professional Competence.
  Graduate Hospital)
• Vice Chairman of Medicine                                      • Commitment to Honesty with Patients.
                                                                                             y
  (Graduate Hospital)                                            • Commitment to Patient Confidentiality.
• Chief of Integrative Medicine                                  • Commitment to maintaining Appropriate Relations
                                                                                                g pp p
  (Mercy Fitzgerald Hospital)                                      with Patients.
• Physician Advisor Case Management
  (
  (Mercy Fitzgerald Hospital)
       y     g         p )                                       • Commitment to Improving Quality of Care.




      Medical Professionalism in the
                                                                       A Day in the Life of ……… ME
         New Millennium (cont’d)
• Commitment to Improving Access to Care.                        •   A day in the office – clinical cases
• Commitment to Just Distribution of finite                      •   My H & P forms and screening
  Resources.                                                     •   Chiropractic physician – Home Inspector
• C
  Commitment to Scientific Knowledge.
        i        S i ifi K        l d                            •   ME – 3rd Engine at 5 Alarm Fire
• Commitment to Maintaining Trust by
                             g        y
  Managing Conflicts of Interest.
• C
  Commitment to Professional R
        it   tt P f i         l Responsibilities.
                                        ibiliti


                                                                                                                        3
‘HONDA’
                             HONDA                                                  Evidence Based Medicine
•   #1 problem we face
       p
                                                                         • Vit i D Insufficiency
                                                                           Vitamin I ffi i
•   ‘Stupidity is a god given right’ i.e. unaccountable patient              – NEJM 364:3 Jan 20, 2011 p 248 254
•   e.g. ‘Tony Soprano (endothelial dysfunction)
          Tony Soprano’                                                      – “…despite the recent focus in the media on the potential role of
                                                                                       p                                        p
                                                                               vitamin D in reducing the risk of various chronic diseases, this
•   Mediterranean diet study – Metabolic Syndrome                              hypothesis requires testing in large, randomized, controlled
                                                                               trials, and vitamin D cannot currently be recommended for the
    Findings: ½ of the study group did not improve –                           purpose of reducing the risk of heart disease or cancer.”
                went on to diabetes mellitus                             • Vitamin D Insufficiency
•   Galaxy Trial, Jupiter etc
            Trial         etc…                                               – Mayo Clinic Proceedings Jan 2011; 86 (1) p 50 60
                                                                                                          Jan,
                                                                             – “…in adults, vitamin D supplementation reduces the risk of
•   Prevention                                                                 fractures and falls. The evidence for other purported beneficial
•   Treatment
    T t        t                                                               effects of vitamin D is primarily based on observational
                                                                               studies…”
•   Regression




            Evidence Based Medicine                                                 Evidence Based Medicine
    • Vit i D PTH and CV Mortality in Older Adults – Th
      Vitamin D,      d    M t lit i Old Ad lt The                       • Transpalmitoleic acid Metabolic Risk Factors and New Onset Diabetes in
                                                                                            acid,               Factors,
      Rancho Bernardo Study                                                U.S. Adults
                                                                             – Ann Int Med 2010; 153: p 790 799
       – AMJMED 2010, 07, 13                                                 – Good fats vs bad fats. Decreased incidence of atherogenic dyslipidemia, insulin
                                                                                                fats                                     dyslipidemia
       – “…serum levels of 25(OH)D, 1,25(OH)D, and intact PTH were not         resistance and new onset diabetes.
         independently associated with cardiovascular mortality…”        • Effects of Lowering HC Levels with B Vitamins in CV Disease, CA and Case
    • On the Epidemiology of Influenza                                     Specific Mortality
                                                                            p               y
                                                                             – Arch Int Med 170 (18) Oct, 2010 p 1622 1633
       – Virology Journal 2008, 5:29                                         – Dietary supplementation with folic acid to lower homocysteine levels had no
       – Seasonal outbreaks? Increased expression of cathelicidin?             effects within 5 years on cv events or on overall cancer or mortality in the
                                                                               populations studied
                                                                                            studied.
    • Vitamin D and the Heart: Why We Need Large Scale Clinical          • Should Healthy People Take a Multivitamin? (Oliver Wendell Holmes, Sr.)
      Trials                                                                 –   Cleveland Clinic Journal Med 77 (10) Oct, 2010 p 658
       – Cleveland Clinic Journal of Med 77:12 p 903 910                     –   “ at least it won t hurt me may not be true “
                                                                                               won’
       – VITAL trial (vitamin D and omega 3)                                 –   Vitamin E: increased rate of all cause mortality.
                                                                             –   SELECT trial: vitamin E increased prostate cancer / selenium increased
                                                                                 diabetes.

                                                                                                                                                              4
Evidence Based Medicine                                            UpToDate.com
                                                                             UpToDate com – good site to review
• M k d V i bilit of M
  Marked Variability f Monacolin L l i C
                             li Levels in Commercial R d
                                                 i l Red                 • C
                                                                           CAM Rx
  Yeast Rice Products
    – Arch Int Med 170 (9) Oct 2010, p 1722 1727                              –   For cancer
    – Marked variability in monacolin content and potential nephro            –   Rheumatoid disorders
      toxic citrinin.
                                                                              –   St. John’s Wort
• Potential for Interactions Between Dietary Supplements
  and Rx Medications                                                          –   Depression
    – J Am Med 2007.21.014 p 207 211                                          –   Saw Palmetto
    – Mainly anticoagulants and diabetes Rx                                   –   Echinacea
• Mercy Medical News
                                                                              –   Ginko Biloba
    General Urology: Enzyte and prolonged QTc interval.
                                                 interval
    General Infectious Disease: Indian coleus (forskolin) potential Rx        –   LBP
      for UTI.                                                                –   Probiotics




 Role of CAM & Integrative Practices                                                       Common Ground
     in the Future of Healthcare
                                                                         • Countdown to Reform
                                                                           C    td      t R f
• Gone is the “dumbluxation”                                             • 2011 stage 1 meaningful use.
• Gone are the silos Chiros/PCP
            h l       h /                                                • 2012 Accountable Care Organization program
                                                                         • 2012 Independent Payment Advisory Board (IPAB)
• Need to integrate and educate                                          • 2013 stage 2 meaningful use
                                                                                    g            g
    Ourselves & public
                                                                         • 2014 first set of IPAB recommendations due to improve
• Share strengths & resources                                              quality and cut costs
                                                                         • St
                                                                           Stage 3 meaningful use
                                                                                          i f l
• Age old struggle against the Antivaccinationists
    –NEJM 364:2 Jan 11
    –Pertussis epidemic & measles back in the news
                                                                         • 12 Things Doctors Want to Tell Patients
    –Quality indicator for Medicare and other insurance carriers              – Physician Practice 10/10


                                                                                                                                   5
Brave New World                                              MS ACP Program & NUHS
                                                                      • R
                                                                        Rewriting the paradigm
                                                                            iti th        di
• Affordable Care Act and the Future of Clinical Medicine:
  The Opportunities & Challenges
                                                                      • African American Barber Shops?
• ACO’s: The End of Independent Practice?                                – Not a bad idea i.e. education
                                                                         – But did we really fail that badly?
• Patient Centered Medical Neighborhood
                                                                      • Broadening the Scope of Nursing, Psychology and
• Hi h V l Cost Conscious Health Care: Concepts f Cli i i
  High Value, C t C      i   H lth C      C     t for Clinicians t
                                                                 to     Optometry Practices
  Evaluate the Benefits, Harms and Costs of Medical interventions
                                                                      • The Philadelphia Project
                                                                                    p       j
• Can Congress make you buy Broccoli? And why that’s a hard           • Doctor of Chiropractic Medicine and Post Graduate Clinical
  question.                                                             Residency
• The challenges of a (growing) medical assistance population
                                                                      • MS ACP PProgram




                                                                                        MS ACP Courses
                                                                                                                Course Titles
                                                                                            Clinical Neurophysiology I & II
                                                                                            Clinical Skills for the Primary Care Physician
                                                                                            Clinical Problem Solving
                                                                                            Biostatistics & Research Methodology
                                                                                            Mechanisms of Pain
                                                                                            Psychological Issues of Illness
                                                                                            Clinical Nutrition I, II, III
                                                                                                                , ,
                                                                                            Advanced Clinical Laboratory Medicine I & II
                                                                                            Independent Research I & II
                                                                                            Advanced Diagnostic Imaging
                                                                                            Internal Medicine Clinical Rotation
                                                                                            Clinical Neurology I & II
                                                                                            Clinical Pharmacology I, II, III
                                                                                            Pediatrics
                                                                                            Women's & Men's Health / Geriatrics
                                                                                            Ethics & Risk Management
                                                                                            Clinical Competencies
                                                                                            Capstone Defense
                                                                                                                                             6

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Integrative Medicine - Eric J. Deppert

  • 1. OVERVIEW 1. Definition of ‘primary care’ INTEGRATIVE MEDICINE y 2. Healthcare 2014 and beyond Eric J. Deppert, MD, FACP 3. A day in the life of …………. Me Clinical Assistant Professor of Medicine, 4. Evidence based pharmacopoeia & herbal 4 E id b d h i h b l Drexel University College of Medicine treatment Postprofessional Faculty, 5. Role of CAM & integrative practices in the future National University of Health Sciences y of healthcare 6. MS ACP program and NUHS rewriting the book Primary Prevention Secondary Prevention • Protect against disease and disability • Identify and detect disease at its earliest d f dd d l • Immunizations stage, before noticeable • Prevent the spread of communicable diseases • Safe drinking water • BP screening • Seatbelts and airbags • Colorectal screening • Health promotion & wellness • IFG/DM & lipids / – Stress management • Pap smear p – Parenting classes • PSA – Cooking classes 1
  • 2. Tertiary Prevention Healthcare 2014 and Beyond • Locking the barn after the horse is out • 50,000,000 i 50 000 000 uninsured d • 30,000,000 covered (Affordable Care Act) • 95% of my world • 20,000,000 left out? • “Cost containment” Chiro opportunity • Rationing of health care (Arizona MA xplants) • Evidence based medicine • My experience before Affordable Care Act • CASE: Betsy Headache y – MRA dissection – Couldn’t get approved Accreditation Council for Education Graduate Medical Education (ACGME) • Bachelor of Science (BS) degree (4 years) Responsible for the accreditation of post MD medical training • Doctor of Medicine (MD) degree (4 years) Core Competencies – Years 1 & 2: Basic & Clinical Sciences (classroom) – Years 3 & 4: Clinical Rotations / Clerkships • Patient care • Average GPA entering program 3.80/4.00* • Postgraduate Residency (3+ years) Medical knowledge – – PGY PGY 1 2 Internship Resident (Internal Medicine) • Practice based learning & improvement – – PGY PGY 3 4 Resident (Internal Medicine) Chief Medical Resident (Internal Medicine) • Systems based practice • USMLE Parts 1, 2, Clinical Skills, 3 • Interpersonal skills and communication • A American Board of I t i B d f Internal M di i C tifi ti E l Medicine Certification Exam – Recertification (every 10 years) • Professionalism • Upon successful completion of the residency program, one is able to practice medicine independently (pursue licensure) and sit for certification examinations. 2
  • 3. Medical Professionalism in the Positions Held New Millennium • Clinical Assistant, Chairman of Education Assistant • A physician charter: professionalism i th b i of h i i h t f i li is the basis f (Presbyterian/UPenn) medicine’s contract with society. • Director of Ambulatory Care y • Principle of Primacy of Patient Welfare Welfare. (Presbyterian/UPenn) • Principle of Patient Autonomy. • Director Podiatric Medical Consults (Presbyterian/UPenn) • Principle of Social Justice. • Internal Medicine Residency Director (Presbyterian/UPenn and • Commitment to Professional Competence. Graduate Hospital) • Vice Chairman of Medicine • Commitment to Honesty with Patients. y (Graduate Hospital) • Commitment to Patient Confidentiality. • Chief of Integrative Medicine • Commitment to maintaining Appropriate Relations g pp p (Mercy Fitzgerald Hospital) with Patients. • Physician Advisor Case Management ( (Mercy Fitzgerald Hospital) y g p ) • Commitment to Improving Quality of Care. Medical Professionalism in the A Day in the Life of ……… ME New Millennium (cont’d) • Commitment to Improving Access to Care. • A day in the office – clinical cases • Commitment to Just Distribution of finite • My H & P forms and screening Resources. • Chiropractic physician – Home Inspector • C Commitment to Scientific Knowledge. i S i ifi K l d • ME – 3rd Engine at 5 Alarm Fire • Commitment to Maintaining Trust by g y Managing Conflicts of Interest. • C Commitment to Professional R it tt P f i l Responsibilities. ibiliti 3
  • 4. ‘HONDA’ HONDA Evidence Based Medicine • #1 problem we face p • Vit i D Insufficiency Vitamin I ffi i • ‘Stupidity is a god given right’ i.e. unaccountable patient – NEJM 364:3 Jan 20, 2011 p 248 254 • e.g. ‘Tony Soprano (endothelial dysfunction) Tony Soprano’ – “…despite the recent focus in the media on the potential role of p p vitamin D in reducing the risk of various chronic diseases, this • Mediterranean diet study – Metabolic Syndrome hypothesis requires testing in large, randomized, controlled trials, and vitamin D cannot currently be recommended for the Findings: ½ of the study group did not improve – purpose of reducing the risk of heart disease or cancer.” went on to diabetes mellitus • Vitamin D Insufficiency • Galaxy Trial, Jupiter etc Trial etc… – Mayo Clinic Proceedings Jan 2011; 86 (1) p 50 60 Jan, – “…in adults, vitamin D supplementation reduces the risk of • Prevention fractures and falls. The evidence for other purported beneficial • Treatment T t t effects of vitamin D is primarily based on observational studies…” • Regression Evidence Based Medicine Evidence Based Medicine • Vit i D PTH and CV Mortality in Older Adults – Th Vitamin D, d M t lit i Old Ad lt The • Transpalmitoleic acid Metabolic Risk Factors and New Onset Diabetes in acid, Factors, Rancho Bernardo Study U.S. Adults – Ann Int Med 2010; 153: p 790 799 – AMJMED 2010, 07, 13 – Good fats vs bad fats. Decreased incidence of atherogenic dyslipidemia, insulin fats dyslipidemia – “…serum levels of 25(OH)D, 1,25(OH)D, and intact PTH were not resistance and new onset diabetes. independently associated with cardiovascular mortality…” • Effects of Lowering HC Levels with B Vitamins in CV Disease, CA and Case • On the Epidemiology of Influenza Specific Mortality p y – Arch Int Med 170 (18) Oct, 2010 p 1622 1633 – Virology Journal 2008, 5:29 – Dietary supplementation with folic acid to lower homocysteine levels had no – Seasonal outbreaks? Increased expression of cathelicidin? effects within 5 years on cv events or on overall cancer or mortality in the populations studied studied. • Vitamin D and the Heart: Why We Need Large Scale Clinical • Should Healthy People Take a Multivitamin? (Oliver Wendell Holmes, Sr.) Trials – Cleveland Clinic Journal Med 77 (10) Oct, 2010 p 658 – Cleveland Clinic Journal of Med 77:12 p 903 910 – “ at least it won t hurt me may not be true “ won’ – VITAL trial (vitamin D and omega 3) – Vitamin E: increased rate of all cause mortality. – SELECT trial: vitamin E increased prostate cancer / selenium increased diabetes. 4
  • 5. Evidence Based Medicine UpToDate.com UpToDate com – good site to review • M k d V i bilit of M Marked Variability f Monacolin L l i C li Levels in Commercial R d i l Red • C CAM Rx Yeast Rice Products – Arch Int Med 170 (9) Oct 2010, p 1722 1727 – For cancer – Marked variability in monacolin content and potential nephro – Rheumatoid disorders toxic citrinin. – St. John’s Wort • Potential for Interactions Between Dietary Supplements and Rx Medications – Depression – J Am Med 2007.21.014 p 207 211 – Saw Palmetto – Mainly anticoagulants and diabetes Rx – Echinacea • Mercy Medical News – Ginko Biloba General Urology: Enzyte and prolonged QTc interval. interval General Infectious Disease: Indian coleus (forskolin) potential Rx – LBP for UTI. – Probiotics Role of CAM & Integrative Practices Common Ground in the Future of Healthcare • Countdown to Reform C td t R f • Gone is the “dumbluxation” • 2011 stage 1 meaningful use. • Gone are the silos Chiros/PCP h l h / • 2012 Accountable Care Organization program • 2012 Independent Payment Advisory Board (IPAB) • Need to integrate and educate • 2013 stage 2 meaningful use g g Ourselves & public • 2014 first set of IPAB recommendations due to improve • Share strengths & resources quality and cut costs • St Stage 3 meaningful use i f l • Age old struggle against the Antivaccinationists –NEJM 364:2 Jan 11 –Pertussis epidemic & measles back in the news • 12 Things Doctors Want to Tell Patients –Quality indicator for Medicare and other insurance carriers – Physician Practice 10/10 5
  • 6. Brave New World MS ACP Program & NUHS • R Rewriting the paradigm iti th di • Affordable Care Act and the Future of Clinical Medicine: The Opportunities & Challenges • African American Barber Shops? • ACO’s: The End of Independent Practice? – Not a bad idea i.e. education – But did we really fail that badly? • Patient Centered Medical Neighborhood • Broadening the Scope of Nursing, Psychology and • Hi h V l Cost Conscious Health Care: Concepts f Cli i i High Value, C t C i H lth C C t for Clinicians t to Optometry Practices Evaluate the Benefits, Harms and Costs of Medical interventions • The Philadelphia Project p j • Can Congress make you buy Broccoli? And why that’s a hard • Doctor of Chiropractic Medicine and Post Graduate Clinical question. Residency • The challenges of a (growing) medical assistance population • MS ACP PProgram MS ACP Courses Course Titles Clinical Neurophysiology I & II Clinical Skills for the Primary Care Physician Clinical Problem Solving Biostatistics & Research Methodology Mechanisms of Pain Psychological Issues of Illness Clinical Nutrition I, II, III , , Advanced Clinical Laboratory Medicine I & II Independent Research I & II Advanced Diagnostic Imaging Internal Medicine Clinical Rotation Clinical Neurology I & II Clinical Pharmacology I, II, III Pediatrics Women's & Men's Health / Geriatrics Ethics & Risk Management Clinical Competencies Capstone Defense 6