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1
Presented by:
Numair Ahmad,Faisal Muneer
Indus International University
Bs-Microbiology 6th
semester
2
.
3
• Helical,and enveloped
• Multiply in cytoplasm
• Ss-ve sense linear and non segmented,
• Rna is present in it
Classification of Paramyxoviruses
• 150 to 300 nm in diameter
4
Paramyxovirus has various attachment proteins all
over the capsid that stick out as spikes. Theses spikes bind
to the sialic acid that is present on the surface of most
human tissue cells and especially on blood cells. These
proteins also facilitate the virus’s entrance into the cell.
5
Measles
Mumps
6
7
Symptoms
Begins with fever, runny nose, cough, red weepy eyes
Fine rash appears within a few days
Appears first on forehead, then spreads to rest of body
Symptoms generally disappear within 1 week
Many cases complicated by secondary infections
Pneumonia and earaches are most common secondary
conditions
Measles does not kill; instead, it leads to secondary infections
that do kill
Measles
8
9
Causative Agent
Mumps virus
Member of the Paramyxoviridae family
Enveloped
Single stranded RNA genome
Symptoms
Early symptoms
Fever with loss of appetite and headache
Later symptoms
Painful swelling of one or both parotid glands and spasms
Usually makes it difficult to chew and swallow
Symptoms disappear in about a week
Symptoms much more severe in individuals past puberty
10
11
Frequent hand
washing and not
sharing items such
as cups, glasses,
and utensils with an
infected person
should decrease the
spread of virus to
others.
12
Treatment
with
Ribavirin
No Vaccine
to date.
13

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Paramyxovirus

  • 1. 1 Presented by: Numair Ahmad,Faisal Muneer Indus International University Bs-Microbiology 6th semester
  • 2. 2 .
  • 3. 3 • Helical,and enveloped • Multiply in cytoplasm • Ss-ve sense linear and non segmented, • Rna is present in it Classification of Paramyxoviruses • 150 to 300 nm in diameter
  • 4. 4
  • 5. Paramyxovirus has various attachment proteins all over the capsid that stick out as spikes. Theses spikes bind to the sialic acid that is present on the surface of most human tissue cells and especially on blood cells. These proteins also facilitate the virus’s entrance into the cell. 5
  • 7. 7 Symptoms Begins with fever, runny nose, cough, red weepy eyes Fine rash appears within a few days Appears first on forehead, then spreads to rest of body Symptoms generally disappear within 1 week Many cases complicated by secondary infections Pneumonia and earaches are most common secondary conditions Measles does not kill; instead, it leads to secondary infections that do kill Measles
  • 8. 8
  • 9. 9 Causative Agent Mumps virus Member of the Paramyxoviridae family Enveloped Single stranded RNA genome Symptoms Early symptoms Fever with loss of appetite and headache Later symptoms Painful swelling of one or both parotid glands and spasms Usually makes it difficult to chew and swallow Symptoms disappear in about a week Symptoms much more severe in individuals past puberty
  • 10. 10
  • 11. 11 Frequent hand washing and not sharing items such as cups, glasses, and utensils with an infected person should decrease the spread of virus to others.
  • 13. 13