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Tissue HAP

  1. The Tissue Prepared by Ms. Nisha S. Mhaske M.Pharm (Q.A.T) Lecturer, PRES’s COPD, Chincholi. Email : nisha.mhaske@pravara.in
  2. The Tissue  Tissue- a group of cell, which having similar in origin, structure and function are called as tissue.  The group of cells function together to carry out specialized activities.  Histology- Branch of science which deals with the study of tissues.
  3.  According to the structure and function the body tissues can be grouped:-  Fundamental types of tissues- there are 4 types of tissues Fundamental Types of Tissue 1. Epithelial Tissue 2.Muscular Tissue 3. Connective Tissue 4. Nervous Tissue
  4. Classification of Tissue
  5. 1. Epithelial Tissue  Epithelial tissue covers the body externally, lines various cavities and ducts forms glands.  Function of epithelium i. Protection – protects the underlying tissues from friction and injury. ii. Secretion – secretion of certain chemical substances which are utilized by the body or removal outside. Hence, epithelial tissue is also called as Covering Tissue.
  6.  Covering tissue can further be classified as A. Simple epithelium B. Compound epithelium C.  It is made up of single layers of cell.  It is subdivided into 4 types i. Squamous epithelium ii. Cuboidal epithelium iii. Columnar epithelium iv. Ciliated epithelium A. Simple Epithelium
  7. Type of tissue Structure Location Function Squamous Epithelium Single layer of flat cells. It lines the Heart, Blood Vessels, lymphatic vessels, Alveoli of lungs. It permit adequate diffusion, osmosis & filtration.
  8. Type of tissue Structure Location Function Cuboidal Epithelium - Cube Shaped cells arranged on basement membrane - Cuboidal epithelium are also called as Glandular epithelium as it is present in simple glands. Simple glands Secretion & Absorption.
  9. Type of tissue Structure Location Function Columnar Epithelium - Cells are rectangular, like tiny columns - Single layer of cells Lining of GIT Secretes mucus. (Such mucus secreting epithelium cells are called as Goblet Cells.)
  10. Type of tissue Structure Location Function Ciliated Epithelium - Hair like structure present on columnar cells are called cilia. Upper respiratory tract along with goblet cells. - Secrete mucus. - Movement of mucus
  11.  It is composed of multiple layers of cells.  It is further divided into 2 Types i. Stratified Epithelium ii. Transitional Epithelium B. Compound Epithelium i. Stratified Epithelium  It can be divided into:-  Stratified squamous epithelium  Stratified cuboidal epithelium  Stratified columnar epithelium
  12. Type of tissue Structure Stratified Epithelium - The deepest layer of the cells are columnar in shape and as they grow towards the surface, they go on becoming flatted. - As the cells move upward their blood supply restricts, and they become dehydrated, shrunken and harder. - It can be keratinised or non-keratinised - The non-keratinised epithelium does not contain keratin and remains moist.
  13. Type of tissue Structure Location Transitional Epithelium - It is composed of several layers of pear shaped cells. - It is variable in appearance - In relaxed state it looks like stratified cuboidal epithelium and - When stretched the cells become squamous shaped. Found in place where expansion is needed. Eg- urinary bladder.
  14. 2. Muscular Tissue  It contains contractile fibers, they can contract or relax and produce movement.  Function- all the body movements are because of muscle tissues.  It can be further be classified into 3 types:- i. Skeletal or Striated or Voluntary Muscles ii. Smooth or Involuntary or Visceral Muscles iii. Cardiac Muscles
  15. Type of tissue Structure Location Function Skeletal or Striated or Voluntary Muscles - Muscles are present on skeleton, hence named as skeletal -It can be moved by will as it is voluntary - Striations are present, hence it called striated muscles -Striations of dark and light bands present - Cells are nearly cylindrical, forming a long skeletal muscle fiber - Many nuclei are located in the periphery of the cells. Bones (Muscles attached to bones) Movement
  16. Skeletal Muscle One single muscle contain numerous muscle fiber and are attached to bones by tendons.
  17. Type of tissue Structure Location Smooth or Visceral or Involuntary Muscles - It can not be moved by will as it is involuntary - Striations are absent, hence it appear as smooth and therefore the name smooth muscles. - Smooth muscle fiber is small and spindle shaped. i.e. Broad in the centre and tapering at both ends. - Nucleus is located centrally. Internal body organs such as GIT, Blood vessels, Urinary bladder, Respiratory tract
  18. Type of tissue Structure Location Cardiac Tissue - It is striated, but involuntary. -Cell has centrally located nucleus & one or more branches. - Two cardiac muscle fibers are attached by thickened plasma membrane called intercalated discs. -The intercalated discs contain desmosomes (Is junction in tissues that connect adjacent cells) as well as gap junctions. - Because of gap junctions, the action potential is carried throughout the heart rapidly. Heart wall is made up of cardiac muscle.
  19. 3. Connective Tissue  The tissue binds together and supports more active and delicate tissues of the body also provides protection to the internal delicate organs.  It is made up of fibers, cells and ground substance.  These are specially developed cells and are of 2 types :- i. White fibers ii. Yellow fibers
  20. i. The white Fibers  These re wavy and run in bundles with very little matrix.  They are inelastic but can be slightly stretched because of their wavy nature.  They contain protein “Collagen” and yield gelatin on boiling.  Function of White fibers  Forming the ligaments which bind bones together  As an outer protective covering for bones  As an outer protective covering for organs like kidneys, lymph nodes and brain.
  21. ii. Yellow elastic fibers  These run either single or branched.  They are composed of highly elastic material and permit considerable stretching  These fibers are found in such organs as:- large arteries, trachea, bronchi, lungs etc.
  22.  From these fibers the following varieties of connective tissues are formed. 1. Loose connective or Areolar tissue 2. Adipose or fatty tissue 3. Fibrous tissue 4. Bone 5. Cartilage tissue
  23. Type of tissue Structure Location Function Loose connective or Areolar tissue - It consists of a loose network of fibers. - It has semi-solid matrix with the cells, called fibrocytes widely separated by yellow elastic fibers and white fibers. -Under the skin - Between muscles, - Supporting blood vessels and nerves, - Alimentary canal. - Secretion - Supporting other tissues - Connection.
  24. Type of tissue Structure Function Adipose or Fatty Tissue - It consists of a collection of fat cells containing fat globules - The cells are present in the matrix of adipose tissue in varying numbers. - The tissue is found supporting organs such as kidneys and the eyes, between bundles of muscle fibers with areolar tissues under the skin etc. - It is made up of adipocytes, which store triglycerides within it. -It acts as energy reservoir - Good insulator (Poor conductor) prevents heat loss from body. - It protects the delicate organs.
  25. Type of tissue Structure Function Fibrous Tissue - It consists of either white or yellow fibers densely massed together. - It is strong as compared to the loose connective and fatty tissue. - The tissue forms deep or true skin of the body. -It is found in forming skins in tendons and ligaments. Tendon- is a strong cord of white fibrous tissue joining Muscle to Bone. Ligaments- is a strong fibrous cord joining Bone to Bone.
  26. Type of tissue Structure Bone - It is one of the hardest connective tissues in the body. - Basically bone tissue is made up of fibrous tissue which hardens, due to the deposition of mineral salts like calcium, phosphate. - Red bone marrow is present within the canal (Haversian canal) of the bone
  27. Type of tissue Structure Cartilage - It is a specialized types of fibrous tissue. - It is very strong & forms a framework for the outer parts of ear & nose. - It also provides a firm wall to the parts of air passage. - Eg-Larynx & Trachea It has a solid matrix. It is divided into 3 types a. Hyaline cartilage b. White fibrocartilage c. Elastic cartilage / yellow fibrocartilage
  28. Type of tissue Structure Location Hyaline cartilage - It appears as a smooth bluish- white tissue -The cells appear in groups of 2 or more & where they come in contact, the edges appear to the flattened. - The matrix is solid & smooth - On the surface of the parts of the bones which form joints. - Forming the costal cartilages which attach ribs to the sternum. - Forming part of the larynx, trachea & bronchi.
  29. Type of tissue Structure Location White Fibrocartilage - It consists of dense masses of white fibers in a solid matrix with the cells widely dispersed. - It is a tough, slightly flexible tissue. - As pads between the bodies of the vertebrae called inter-vertebral discs. - Between articulating surfaces of bones of the knee joint - Surrounding the rim of the bony sockets of the hip & shoulder joint.
  30. Type of tissue Structure Location Yellow Fibrocartilage - It consist of yellow, elastic, fibers running through solid matrix. - The cells lie between the fibers. - It forms the pinna or lobe of ear & the epiglottis.
  31.  The neuron or nerve cell is made up of 1. Cell body 2. Axons 3. Dendrites Type of tissue Structure Nervous Tissue - Nervous tissue is made up of nerve cells (Neuron) and Neuralgia.
  32. 1. Cell body  It contains nucleus & other organelles 2. Dendrites  These are input portions of a neuron.  These are usually short & highly branched  Each nerve cell contain many dendrites. 3. Axons  Generally each nerve cell contain ingle axon, which is thin, long & cylindrical process & is major output portion of a neuron.  The membrane of an axon is called axolemma which contain axoplasm.  Most of the axons are surrounded by a sheath of fatty material called Myelin sheath.
  33.  The mylein sheath is absent at intervals along the length of the axon and near its branching end.  These intervals are called “Node of Ranvier” and they contribute to rapid transmission of nerve impulses along myelinated fibers.  Neurilemma :- It is a very fine, delicate membrane surrounding the axons of al peripheral nerves.  It consists of a series of “Schwann cells” which surround the axon & the myelin sheath.
  34. Types of Neurons Sensory or Afferent neurons Motor or Efferent neurons Intercalated neurons These neurons transmit impulses from the periphery of the body to the spinal cord and then to the brain where they are interpreted and sensed. Eg- Sense of taste, sight, touch etc. These neurons convey impulses from the brain & spinal cord to other parts of body stimulating glandular secretion or causing muscle contraction. These are found between sensory & motor neurons and forms link in the pathways of nerve.
  35. Synapse  The point at which the nerve impulses passes from one neuron to another neuron is called synapse.  Various chemicals known as transmitters are secreted in the synapse and are involved in the transmission of information across the synapse.
  36. Body fluids • Water is the universal medium in which all metabolic reactions occur. • About 60% of our body weight is made up of water. • Water along with dissolved substances in it, constitute body fluids. • A major proportion of body fluid is found intracellularly i.e. in the form of protoplasm. • There are four body fluid compartments as follows:- i. Intracellular ii. Extracellular (Tissue fluid) iii. Circulatory system (Blood plasma & Lymph) iv. Transcellular fluid compartment (CSF, Synovial Fluid, Serous Fluid etc.)
  37. Cerebrospinal Fluid- Present in subarachnoid space in the meninges of CNS Serous Fluid- Present in different serous membranes (pale yellow & transparent fluid) Synovial Fluid- Found in cavities of synovial joints (Viscous & Non-Newtonian fluid)
  38. Thank you
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