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A Trial of Darbepoetin Alfa in Type 2 Diabetes and Chronic Kidney Disease NEJM Volume 361:2019-2032   November 19, 2009   Number 21 Wafa Badwan, MD March 16, 2010
Introduction ,[object Object],[object Object],[object Object]
Introduction ,[object Object],[object Object]
Methods ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Study Population ,[object Object],[object Object],[object Object],[object Object]
Study Population ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Study Procedures ,[object Object],[object Object],[object Object],[object Object]
Study Procedures ,[object Object],[object Object]
Study Procedures ,[object Object],[object Object],[object Object],[object Object]
Study Procedures ,[object Object],[object Object]
Evaluation of Outcomes ,[object Object],[object Object]
Monitoring ,[object Object],[object Object],[object Object]
Statistical Analysis ,[object Object],[object Object],[object Object],[object Object],[object Object]
Results ,[object Object],[object Object],[object Object],[object Object]
Results ,[object Object],[object Object],[object Object],[object Object]
Results ,[object Object],[object Object],[object Object],[object Object]
Results ,[object Object],[object Object],[object Object],[object Object],[object Object]
Figure 1- Mean Hemoglobin levels through 48 months among patients who were assigned to receive Darbepoetin Alfa or placebo
Results ,[object Object],[object Object],[object Object],[object Object]
Results ,[object Object],[object Object],[object Object]
Figure 2 Kaplan-Meier Estimates of the Probability of the Primary and Secondary End Points
Figure 3- Kaplan Meier Estimates of the Probability of Renal Outcomes
Table 2
Results ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Results ,[object Object],[object Object]
Summary ,[object Object],[object Object]
Summary ,[object Object],[object Object],[object Object],[object Object]
Summary ,[object Object]

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Journal Club March 2010

  • 1. A Trial of Darbepoetin Alfa in Type 2 Diabetes and Chronic Kidney Disease NEJM Volume 361:2019-2032 November 19, 2009 Number 21 Wafa Badwan, MD March 16, 2010
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18. Figure 1- Mean Hemoglobin levels through 48 months among patients who were assigned to receive Darbepoetin Alfa or placebo
  • 19.
  • 20.
  • 21. Figure 2 Kaplan-Meier Estimates of the Probability of the Primary and Secondary End Points
  • 22. Figure 3- Kaplan Meier Estimates of the Probability of Renal Outcomes
  • 24.
  • 25.
  • 26.
  • 27.
  • 28.