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DNA stands for deoxyribose nucleic acid
-This chemical substance is present in the nucleus of all cells in all living organisms
-DNA controls all the chemical changes which take place in cells
-The kind of cell which is formed, (muscle, blood, nerve etc) is controlled by DNA
-The kind of organism which is produced (buttercup, giraffe, herring, human etc)
is controlled by DNA
DNA 2
-DNA is a very large molecule made up of a long chain of sub-units
-The sub-units are called nucleotides
-Each nucleotide is made up of:
. a sugar called deoxyribose
. a phosphate group -PO4 and
. an organic base
DNA molecule 3
-Ribose is a sugar, like glucose, but with only five carbon atoms in its molecule
-Deoxyribose is almost the same but lacks one oxygen atom
-Both molecules may be represented by the symbol
Ribose & deoxyribose 4
The most common organic bases are
Adenine (A)
Thymine (T)
Cytosine (C)
Guanine (G)
The bases 5
The deoxyribose, the phosphate and one of the bases
adenine
deoxyribose
PO4
Combine to form a nucleotide
Nucleotides 6
A molecule of DNA is formed
by millions of nucleotides
joined together in a long
chain
PO4
PO4
PO4
PO4
sugar-phosphate
backbone
+ bases
Joined nucleotides 7
-In fact, the DNA usually consists of a double strand of nucleotides
-The sugar-phosphate chains are on the outside and the strands are held together
by chemical bonds between the bases
8
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
2-stranded DNA 9
The bases always pair up in the same way
Adenine forms a bond with Thymine
and Cytosine bonds with Guanine
Bonding 1 10
Adenine Thymine
Cytosine Guanine
PO4
PO4
PO4
thymine
PO4
PO4
PO4
PO4
adenine
cytosine
PO4
guanine
Bonding 2 11
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
PO4
Pairing up 12
The paired strands are coiled into a spiral called
A DOUBLE HELIX
13
sugar-phosphate
chain
bases
THE DOUBLE HELIX
14

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