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Lectures on Gynecology 
Dr Magda Helmi
Causes of benign ovarian cysts 
Functional 
Inflammatory 
Germ cell 
Epithelial 
Sex cord stromal 
Follicular cyst 
Corpus Luteal cyst 
Theca Luteal cyst 
Tubo-ovarian abscess 
Endometrioma 
Benign teratoma 
Serous cyst adenoma 
Mucinous cyst adenoma 
Brenner tumour 
Fibroma 
thecoma
Functional 
Follicular cyst 
Graafian follicle cyst or follicular cyst 
is a type of functional simple cyst, 
and is the most common type of 
ovarian cyst 
This type can form when ovulation 
doesn't occur, 
Usually, these cysts produce no 
symptoms and disappear by 
themselves , Its rupture can create 
sharp, severe pain on the side of the 
ovary . On a sonogram, simple 
ovarian cysts have a uniformly thin, 
rounded wall and a unilocular 
appearance that is either hypoechoic 
or anechoic. They usually measure 
2.5-15 cm in diameter
Functional 
Corpus Luteal cyst 
Corpus Luteal cysts 
occur following ovulation 
and may present with 
pain due to rupture and 
or hemorrhage, typically 
late in the menstrual 
cycle. 
Treatment is expectant, 
with analgesia. 
Occasionally, surgery 
may be necessary to 
wash out the pelvis and 
perform an ovarian 
cystectomy.
Functional 
Theca Luteal cyst 
Theca Luteal cysts are 
associated with 
pregnancy, particularly 
multiple pregnancies, 
and are often 
diagnosed incidentally 
at routine USS. 
Most resolve 
spontaneously during 
pregnancy.
Inflammatory 
ovarian cysts Tubo-ovarian 
abscess 
Are present in 14-38% of 
patients hospitalized with pelvic 
inflammatory disease (PID) . 
Commonly seen in patients with 
poor access to routine 
gynecologic care. 
The traditional criteria for the 
diagnosis of PID include 
subjective bilateral abdominal 
pain per patient report and 
positive physical examination 
findings for bilateral adnexal 
tenderness at palpation and 
cervical motion tenderness. 
A hydrosalpinx is generally 
anechoic, whereas a pyosalpinx 
may have increased echoes 
within the fluid.
Germ cell 
Benign teratoma 
These are the most common 
ovarian tumours in young 
women, peak incidence is in 
the early 20s accounting for 
more than 50 per cent of 
ovarian tumours in this age 
group. 
Dermoid cysts are a 
combination of all tissue 
types (mesenchymal, 
epithelial and stroma). 
Diagnosis may be incidental, 
although 15 per cent present 
acutely with torsion . 
Treatment is often surgical 
excision.
Benign Epithelial Ovarian 
Cysts 
Epithelial cystic tumors account for about 
60% of all true ovarian neoplasm. One third 
of all ovarian tumors are serous, and two 
thirds of these serous tumors are benign. By 
definition, serous tumors are characterized 
by a proliferation of epithelium resembling 
that lining the fallopian tubes. 
Mucinous cysts are usually smooth-walled; 
compared with the serous variety; they rarely 
are associated with true papillae. 
Treatment 
For women of childbearing age, simple 
unilateral oophorectomy via laparoscopy or 
laparotomy is adequate 
Mucinous 
cyst 
Serous 
cyst
Benign Solid Ovarian 
Tumors 
Brenner tumors are usually found 
incidentally at pathologic evaluation, 
often in conjunction with a mucinous 
cystadenoma or dermoid cyst. They 
are relatively rare tumors and are 
most common in the fifth to sixth 
decades of life. 
Solid mature teratomas are tumors 
consisting of differentiated tissue 
from all 3 germ layers. Benign 
teratomas 
Treatment 
In most instances, simple excision of 
the solid tumors is adequate therapy, 
particularly for women of 
reproductive age.
Fibroma 
The most common benign solid tumor of the 
ovary is the fibroma 
It is derived from connective tissue and arise 
from the solid ovarian cortical stroma. 
Histologically, spindle cells are seen. 
Ultrasonographically, these tumors appear 
hypoechoic with attenuation of the ultrasound 
beam. 
On magnetic resonance imaging (MRI), it 
demonstrate low-signal intensity. 
These tumors may undergo calcification and 
degeneration. Approximately 10-15% are 
found in association with ascites. 
Fewer than 1% undergo malignant 
transformation to fibrosarcomas. About 1% of 
cases are associated with Meigs syndrome, 
characterized by ovarian fibroma, ascites, and 
pleural effusion.

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Benign diseases of the ovary

  • 1. Lectures on Gynecology Dr Magda Helmi
  • 2. Causes of benign ovarian cysts Functional Inflammatory Germ cell Epithelial Sex cord stromal Follicular cyst Corpus Luteal cyst Theca Luteal cyst Tubo-ovarian abscess Endometrioma Benign teratoma Serous cyst adenoma Mucinous cyst adenoma Brenner tumour Fibroma thecoma
  • 3. Functional Follicular cyst Graafian follicle cyst or follicular cyst is a type of functional simple cyst, and is the most common type of ovarian cyst This type can form when ovulation doesn't occur, Usually, these cysts produce no symptoms and disappear by themselves , Its rupture can create sharp, severe pain on the side of the ovary . On a sonogram, simple ovarian cysts have a uniformly thin, rounded wall and a unilocular appearance that is either hypoechoic or anechoic. They usually measure 2.5-15 cm in diameter
  • 4. Functional Corpus Luteal cyst Corpus Luteal cysts occur following ovulation and may present with pain due to rupture and or hemorrhage, typically late in the menstrual cycle. Treatment is expectant, with analgesia. Occasionally, surgery may be necessary to wash out the pelvis and perform an ovarian cystectomy.
  • 5. Functional Theca Luteal cyst Theca Luteal cysts are associated with pregnancy, particularly multiple pregnancies, and are often diagnosed incidentally at routine USS. Most resolve spontaneously during pregnancy.
  • 6. Inflammatory ovarian cysts Tubo-ovarian abscess Are present in 14-38% of patients hospitalized with pelvic inflammatory disease (PID) . Commonly seen in patients with poor access to routine gynecologic care. The traditional criteria for the diagnosis of PID include subjective bilateral abdominal pain per patient report and positive physical examination findings for bilateral adnexal tenderness at palpation and cervical motion tenderness. A hydrosalpinx is generally anechoic, whereas a pyosalpinx may have increased echoes within the fluid.
  • 7. Germ cell Benign teratoma These are the most common ovarian tumours in young women, peak incidence is in the early 20s accounting for more than 50 per cent of ovarian tumours in this age group. Dermoid cysts are a combination of all tissue types (mesenchymal, epithelial and stroma). Diagnosis may be incidental, although 15 per cent present acutely with torsion . Treatment is often surgical excision.
  • 8. Benign Epithelial Ovarian Cysts Epithelial cystic tumors account for about 60% of all true ovarian neoplasm. One third of all ovarian tumors are serous, and two thirds of these serous tumors are benign. By definition, serous tumors are characterized by a proliferation of epithelium resembling that lining the fallopian tubes. Mucinous cysts are usually smooth-walled; compared with the serous variety; they rarely are associated with true papillae. Treatment For women of childbearing age, simple unilateral oophorectomy via laparoscopy or laparotomy is adequate Mucinous cyst Serous cyst
  • 9. Benign Solid Ovarian Tumors Brenner tumors are usually found incidentally at pathologic evaluation, often in conjunction with a mucinous cystadenoma or dermoid cyst. They are relatively rare tumors and are most common in the fifth to sixth decades of life. Solid mature teratomas are tumors consisting of differentiated tissue from all 3 germ layers. Benign teratomas Treatment In most instances, simple excision of the solid tumors is adequate therapy, particularly for women of reproductive age.
  • 10. Fibroma The most common benign solid tumor of the ovary is the fibroma It is derived from connective tissue and arise from the solid ovarian cortical stroma. Histologically, spindle cells are seen. Ultrasonographically, these tumors appear hypoechoic with attenuation of the ultrasound beam. On magnetic resonance imaging (MRI), it demonstrate low-signal intensity. These tumors may undergo calcification and degeneration. Approximately 10-15% are found in association with ascites. Fewer than 1% undergo malignant transformation to fibrosarcomas. About 1% of cases are associated with Meigs syndrome, characterized by ovarian fibroma, ascites, and pleural effusion.