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Health Effects Of Anesthetic Agents On Operating Room Personnel

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Margaret Czart
Margaret Czart

Docotral course final project presentation.

EducaçãoSaúde e medicina
1 de 21
Health Effects of Anesthetic Agents on Operating Room Personnel with Special Emphasis on Sevoflurane and Nitrous Oxide By Margaret Czart, MPH
Introduction ,[object Object],[object Object],[object Object],[object Object],[object Object]
Inhalation Anesthetic Agents C2HBrClF3 C3H2ClF5O C3H2ClF5O (Fluothane) a,b (Ethrane) a,b (Forane) a,b C3H2F6O C4H3OF7 N2O (Suprane) a,b (Ultane) a,b (Nitrous Oxide) a,b Source: a)OSHA 2000 , b) Evers et. al. 2006
Metabolism – Halogenated Agents Source: Reichle et.al, 2003
Metabolism - Sevoflurane Source: Abbott Laboratories, 2006
Metabolism - Sevoflurane Source: Abbott Laboratories, 2006
Metabolism – Nitrous Oxide ,[object Object],[object Object],[object Object]
Animal Studies ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Animal Studies ,[object Object],[object Object],[object Object],[object Object],[object Object]
Animal Studies ,[object Object],[object Object],[object Object]
Clinical Studies ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical Studies- Halogenated ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical Studies - Sevoflurane ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical Studies – Nitrous Oxide ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Diagnosis - Sevoflurane ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Diagnosis – Nitrous Oxide ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Regulations N/A 50 ppm (8hr day) (40 hr week) 2ppm (1 hr) 0.5 ppm (w halogenated) Nitrous Oxide N/A N/A 2ppm (1 hr) 0.5 ppm (w N2O) Sevoflurane N/A 75 ppm 2ppm (1 hr) 0.5 ppm (w N2O) Desflurane N/A 75 ppm 2ppm (1 hr) 0.5 ppm (w N2O) Isoflurane N/A 75 ppm 2ppm (1 hr) 0.5 ppm (w N2O) Enflurane N/A 50 ppm (8hr day) (40 hr week) 2ppm (1 hr) 0.5 ppm (w N2O) Halothane PEL TLV REL Agent
Public Health Prevention ,[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusion ,[object Object],[object Object],[object Object]
Thank You!

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Health Effects Of Anesthetic Agents On Operating Room Personnel

  • 1. Health Effects of Anesthetic Agents on Operating Room Personnel with Special Emphasis on Sevoflurane and Nitrous Oxide By Margaret Czart, MPH
  • 2.
  • 3. Inhalation Anesthetic Agents C2HBrClF3 C3H2ClF5O C3H2ClF5O (Fluothane) a,b (Ethrane) a,b (Forane) a,b C3H2F6O C4H3OF7 N2O (Suprane) a,b (Ultane) a,b (Nitrous Oxide) a,b Source: a)OSHA 2000 , b) Evers et. al. 2006
  • 4. Metabolism – Halogenated Agents Source: Reichle et.al, 2003
  • 5. Metabolism - Sevoflurane Source: Abbott Laboratories, 2006
  • 6. Metabolism - Sevoflurane Source: Abbott Laboratories, 2006
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18. Regulations N/A 50 ppm (8hr day) (40 hr week) 2ppm (1 hr) 0.5 ppm (w halogenated) Nitrous Oxide N/A N/A 2ppm (1 hr) 0.5 ppm (w N2O) Sevoflurane N/A 75 ppm 2ppm (1 hr) 0.5 ppm (w N2O) Desflurane N/A 75 ppm 2ppm (1 hr) 0.5 ppm (w N2O) Isoflurane N/A 75 ppm 2ppm (1 hr) 0.5 ppm (w N2O) Enflurane N/A 50 ppm (8hr day) (40 hr week) 2ppm (1 hr) 0.5 ppm (w N2O) Halothane PEL TLV REL Agent
  • 19.
  • 20.