A university researcher died from an infection caused by bacteria he was studying. The bacteria, Yersinia pestis, causes plague. An autopsy found the bacteria in his body but no obvious cause of death. More tests are planned as no other illnesses have been reported. Biosafety aims to reduce risks from exposure to infectious agents through standard practices, containment equipment, facility design and other principles outlined in publications like the Biosafety in Microbiological and Biomedical Laboratories manual. Risk assessments consider the organism, procedures, containment and other factors to determine appropriate biosafety levels and practices.

1. Basic Biosafety Principles EH&S Academy Brenda J. Wong, UCSD Biosafety Officer October 2009

11. Transgenic Insects

15. The BMBL continues to be published by the CDC and the NIH 5th edition is now at the printers http://www.cdc.gov/od/ohs/biosfty/bmbl5/bmbl5toc.htm Biosafety Concepts The BMBL

23. Laboratory Design “ Warehouse Type Lab”

37. UCSD’s BSL-3

41. Animal Biosafety Level-4 Working in High Containment

44. Animal Containment Points CDC - 1957 CDC & UCSD - 2005 Courtesy of Paul Vinson, CDC

47. Risk Assessment In-Vitro In-Vivo Human Clinical Trial

54. What Helps?