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Pmy 5600 course handbook 2014
1. University of Zambia
School of Medicine
Department of Pharmacy
Terms I – 4
Period: 2015/2016
PMY 5600 Course Syllabus
Course Information
Course Title CLINICAL PHARMACY & THERAPEUTICS
Course Code PMY 5600
Prerequisites Pharmacy Practice & Clinical Pharmacology of 4th
Year Pharmacy
Course Website TBS (To be sourced)
Course Coordinator ??
Total Teaching Hours 120 Hours
Total Contact Hours for Lab /
Clinical/Tutorials / Workshops
Sessions
120 Hours
Course Description - Clinical pharmacy is health training discipline with “a patient centered, outcomes oriented-
pharmacy practice that requires the pharmacist to work together with the patient and the
healthcare team members to promote health, prevent disease, assess, monitor, initiate and
modify medication use.
- Clinical Pharmacy is one of the main health science discipline in pharmacy training that
embodies the application and development, by trained pharmacists, of scientific principles of
pharmacology, toxicology, therapeutics, clinical pharmacokinetics, pharmacoeconomics,
pharmacogenomics, and other life-based pharmaceutical sciences of various diseases for the
care of patients.
A. ………..Credit Units
B. AIM: To provide students with the ability to integrate the knowledge principles of pharmaceutical sciences, social sciences and
pharmacotherapeutical aspects of various diseases in order to make sound and therapeutic decisions.
C. The OBJECTIVES of the course are to:
i. Develop clinical pharmacy skills in the students to solve clinical-based health issues
ii. To provide them an environment to increase their understanding and ability problems of pharmacotherapy in nature.
iii. To develop professionalism and life-long learning in contributions towards patient care provision
iv. To employ effective communication and critical skills in presenting patient cases
TEXTBOOKS
1. Book Title CLINICAL PHARMACY AND THERAPEUTICS
Author(s) Roger Walker & Cate Whittlesea
Publisher Churchhill Livingstone ELSEVIER
Year 2012
Edition Fifth Edition
ISBN 978-0-7020-4294-2
2. Book Title CLINICAL SKILLS FOR PHARMACISTS - A Patient-Focused Approach
Editors Karen J. Tietze
Publisher ELSEVIER MOSBY
Year 2012
Edition 3rd
Edition
ISBN 978-0-323-05485-0 (alk. paper)
3. Book Title CLINICAL PHARMACY AND THERAPEUTICS
Editors Roger Walker & Cate Whittlesea
Publisher Churchhill Livingstone ELSEVIER
Year 2012
Edition 3rd
Edition
ISBN
4. Book Title CLINICAL SKILLS
2. Authors Robert Turner & Roger Blackwood
Publisher Blackwell Science
Year 2003
Edition 4th
Edition
ISBN 0-632-06511-7
5. Book Title OXFORD HANDBOOK OF CLINICAL PHARMACY
Author Philip Wiffen, Marc Mitchell, Melanie Snelling and Nicola Stoner
Publisher Oxford Medical Publications
Year 2012
Edition 2nd
Edition
ISBN 978-0-19-960364-0
Other references
6. Encyclopaedia of Clinical Pharmacy, Joseph T. DiPiro, 2003
7. Lecture Notes in Pharmacy Practice, Lilian M Azzopardi, 2010
8. Basic and Clinical Pharmacology. McGraw Hill,2011
9. Pharmacotherapy Principles and Practice Study Guide: A case based care plan approach, 2011
10. The Clinical Use of Drugs, 2009
11. Pharmacotherapy principles & practice, 2008
Assessment
Assessment Due Date Percentage
Test 1 08/12/2016 15%
Test 2 20/04/2016 15%
Assignments TBC 5%
Laboratory Reports TBA 5%
Course Competences
THE EXPECTED COMPETENCES ARE:
- Posses skills and competencies for various types of pharmacy practice services
- Trained personnel to respond to symptoms of various ailments with confidence during the provision of pharmaceutical care
- Deliver appropriate pharmaceutical care service to all health-seeking people with assurance
- Possess and exhibit appropriate and effective communication skills during the pharmaceutical care provision
Teaching & Learning Methods
1. Class lectures and lecture notes are designed to achieve the course objectives.
2. Students should read the assigned topics from recommended textbooks before class and participate in class.
3. Students should ask questions - Ask lots of questions.
4. Tutorials will be conducted to encourage discussions and further understanding of material taught in lectures.
5. Students are expected to have answers to tutorial questions for them to be allowed to attend.
6. Students are expected to attend ALL lectures. Students with less than 85% attendance will not be allowed to write end of year
examinations*
7. Students should undertake ALL laboratory practicals
8. You are responsible for all material covered in this course.
9. Please communicate any concerns or issues either in class, or during the tutorials
COURSE CONTENT
UNIT
TOPICS
TIME (hours) REFERENCE
1. General Introduction to the
Concept of Clinical Pharmacy
Clinical pharmacy process
- Development of clinical practice in pharmacy
- Pharmaceutical care service
- Pharmaceutical consultation
- Clinical pharmacy functions and knowledge
Prescribing
- Rational and effective prescribing
- Pharmacists as prescribers and the legal
framework
- The prescribing process
- Medication review process
- Factors that influence prescribers
- Strategies to influence prescribing
Practical pharmacokinetics
- General applications
- Application to therapeutic drug monitoring
- Basic concepts
- Clinical applications
Drug interactions
- Epidemiology
- Mechanisms of drug interactions
- Assessing the safety of drugs
3. - Classification of ADRs
- Factors affecting susceptibility to ADRs
- Immunological reactions
- Formulation issues contributing to ADRs
- Pharmacovigilance and epidemiological methods
in ADR detection
- Roles of health professionals
Laboratory data
- Biochemical data
- Liver function tests (LFTs)
- Cardiac markers
- Tumour markers
- Immunoglobulins
- Haematology data
- Other blood tests
- Monitoring anticoagulant therapy
Parenteral nutrition
- Introduction
- Components of a PN regimen
- Administration of PN
- Pharmaceutical issues
- Nutritional assessment and monitoring
- Specific disease states
- Paediatric PN
Pharmacoeconomics
- Terms used in health economics
- Types of health economic evaluations
- Costs and consequences
20
1: Chapter 1-8
2. Life stages Neonates
- Drug disposition
- Major clinical disorders
- Principles and Goals of Therapy
Paediatrics
- Demography
- The normal child
- Drug disposition
- Drug therapy in children
- Counselling, adherence and concordance
- Medicines in schools
- Monitoring parameters
- Adverse drug reactions
- Medication errors
- Licensing medicines for children
- Service frameworks
Geriatrics
- Pharmacokinetics
- Pharmacodynamics
- Common clinical disorders
- Principles and goals of drug therapy in the
elderly
20
1: Chapter 9-11
3. Required Clinical Skills for
pharmacists
Introduction: The Practice of Clinical Pharmacy
- Patient-focused pharmacy practice
- The clinical environment
- The health care delivery system
Communication Skills for the Pharmacist
- Verbal communication skills
- Written communication skills
- Integration
- Telecommunication
- Additional communication skills
Taking Medication Histories
- Preparation for the interview
- Observation of the patient and the patient’s
Environment
- Data to be obtained
- The difficult interview
- Documentation of the medication history
Physical Assessment Skills
- The Process
- Inspection, Palpation, Percussion, and
Auscultation Techniques
- Equipment
- Vital Signs
- Skin
- Head and Neck
- Chest and Lungs
- Right Side of the Diaphragm
- Left Side of the Diaphragm
- Anterior
- Posterior
- Cardiovascular System
- Point of Maximal Impulse (PMI)
- Heart Sounds and Murmurs
20
2: Chapters 1-10
4. - Breasts and Axillae
- Abdomen
- Bowel Sounds
- Liver Span & Edge
- Musculoskeletal System
- Neurologic System
- Short-Term Memory
- Orientation
- Abstract Thinking
- Cerebellar Function
- Sensory Function (Graphesthesia)
- Monofilament Foot Examination
- Patellar Reflex
- Muscle Strength
- Muscle Tone
Review of Laboratory and Diagnostic Tests
- Background
- General Organ Systems
- Cardiovascular System
- Cardiovascular System
- Cardiovascular System
- Hematologic System
- Immunologic System
- Neurologic System
- Renal System
- Respiratory System
- Biomarkers
- Nutrition
- Infectious Disease
The Patient Case Presentation in Components
- General patient information
- Chief complaint
- History of present illness
- Past medical history
- Social history
- Family history
- Medication history
- Review of systems
- Physical examination
- Laboratory and diagnostic results
- Patient problem list
- Progress
- Other information
Therapeutics Planning
- Identify the problems
- Prioritize the problems
- Select patient-specific drug and nondrug
Interventions
- Develop a monitoring plan
- Soap format
Monitoring Drug Therapies
- The process
- Application and integration
Researching and Providing Drug Information
- The Process
- Sample drug information questions
Ethics in Pharmacy and Health Care
- Professional codes of ethics
- Ethical issues
4. Therapeutics Gastrointestinal System Disorders
- Description to identify the conditions
- Causes of the conditions
- Identification of chemical substances possibly
causing the conditions
- Appropriate pharmaceutical care plan /
Treatment of the condition for each condition
- Any other relevant and additional information
Cardiovascular System Disorders
- Description to identify the conditions
- Causes of the conditions
- Identification of chemical substances possibly
causing the conditions
- Appropriate pharmaceutical care plan /
Treatment of the condition for each condition
- Any other relevant and additional information
Respiratory System Disorders
- Description to identify the conditions
- Causes of the conditions
- Identification of chemical substances possibly
causing the conditions
- Appropriate pharmaceutical care plan /
Treatment of the condition for each condition
- Any other relevant and additional information
5. Central Nervous System Disorders
- Description to identify the conditions
- Causes of the conditions
- Identification of chemical substances possibly
causing the conditions
- Appropriate pharmaceutical care plan /
Treatment of the condition for each condition
- Any other relevant and additional information
Endocrine System Disorders
- Description to identify the conditions
- Causes of the conditions
- Identification of chemical substances possibly
causing the conditions
- Appropriate pharmaceutical care plan /
Treatment of the condition for each condition
- Any other relevant and additional information
Hepatic Disorders
- Description to identify the conditions
- Causes of the conditions
- Identification of chemical substances possibly
causing the conditions
- Appropriate pharmaceutical care plan /
Treatment of the condition for each condition
- Any other relevant and additional information
Obstetric & Gynecological System Disorders
- Description to identify the conditions
- Causes of the conditions
- Identification of chemical substances possibly
causing the conditions
- Appropriate pharmaceutical care plan /
Treatment of the condition for each condition
- Any other relevant and additional information
Urological System Disorders
- Description to identify the conditions
- Causes of the conditions
- Identification of chemical substances possibly
causing the conditions
- Appropriate pharmaceutical care plan /
Treatment of the condition for each condition
- Any other relevant and additional information
Haematopoietic Disorders
- Description to identify the conditions
- Causes of the conditions
- Identification of chemical substances possibly
causing the conditions
- Appropriate pharmaceutical care plan /
Treatment of the condition for each condition
- Any other relevant and additional information
Malignant Disorders
- Description to identify the conditions
- Causes of the conditions
- Identification of chemical substances possibly
causing the conditions
- Appropriate pharmaceutical care plan /
Treatment of the condition for each condition
- Any other relevant and additional information
Rheumatic Disorders & Immunological
- Description to identify the conditions
- Causes of the conditions
- Identification of chemical substances possibly
causing the conditions
- Appropriate pharmaceutical care plan /
Treatment of the condition for each condition
- Any other relevant and additional information
Eye Disorders
- Description to identify the conditions
- Causes of the conditions
- Identification of chemical substances possibly
causing the conditions
- Appropriate pharmaceutical care plan /
Treatment of the condition for each condition
- Any other relevant and additional information
Skin Disorders
- Description to identify the conditions
- Causes of the conditions
- Identification of chemical substances possibly
causing the conditions
- Appropriate pharmaceutical care plan /
Treatment of the condition for each condition
- Any other relevant and additional information
20
2: Chapters 8-9
1: Chapter 12-58
7: Chapter 12-61
6. Additional Notes
Examination
Format
Two papers: Paper I and Paper II: Exact format TBC to students at least 14 days before the date of
Examination
Supplementary
Exams
TBA by senate: Format will be similar to that of the main examination
Estimated end
Date
Lectures to end as soon as study period begins
Cheating /
Unusual activities
The University Zambia Policy on this issue, please read
Attendance 100% attendance in all activities is expected.
Continuous
Assessment [CA]
Please take CA very serious. Students with no CA will not be allowed to sit for final examinations