7 ChemotherapySYNTHETIC MEDICINAL AGENTS (DRUGS)

SYNTHETIC MEDICINAL AGENTS (DRUGS) MAJID MOHIUDDIN

SULFONAMIDES ,[object Object],[object Object],[object Object]

Chemistry of Sulfonamides ,[object Object],[object Object],[object Object]

Sulfacetamide sod., Sulfasalazine, Mafenide, silversulfadiazine. Special purpose sulfonamides 4. Sulfadoxine, Sulfamethopyrazine. Long acting (~7days) 3. Sulfamethoxazole, Sulfamoxole. Intermediate acting (8-12hr) 2. Sulfadiazine, Sulfisoxazole. Short acting (4-8hr) 1. DRUGS LIFE S.No.

Antibacterial Spectrum of Sulfonamides. ,[object Object],[object Object],[object Object],[object Object],[object Object]

Mechanism of Action of Sulphonamides ,[object Object],[object Object],[object Object],[object Object],[object Object]

Resistance to sulfonamides ,[object Object],[object Object],[object Object],[object Object],[object Object]

Pharmacokinetics of Sulphonamides ,[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

ADVERSE EFFECTS OF SULPHONAMIDES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Uses of Sulphonamides ,[object Object],[object Object],[object Object],[object Object]

P-AMINOSALISYLIC ACID ISONIAZID

CH=N.NH.CS.NH 2 CH3CO.NH PROTHIONAMIDE C.NH 2 S C 3 H 7 THIACETAZONE

CH 3 CH 2 CHNH(CH 2 ) 2 NHCHCH 2 CH 3 CH 2 OH CH 2 OH .2HCL ETHAMBUTOL

[object Object],o Furan o NO 2 CHO 5-nitrofurfural

[object Object],NALIDIXIC ACID

QUINOLINE NALIDIXIC ACID NORFLOXACIN

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],METRONIDAZOLES

[object Object],MAJID MOHIUDDIN

7 ChemotherapySYNTHETIC MEDICINAL AGENTS (DRUGS)

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7 ChemotherapySYNTHETIC MEDICINAL AGENTS (DRUGS)