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529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
September	
  is	
  Prostate	
  Cancer	
  Awareness	
  Month!	
  	
  
	
  
A	
  prostate	
  cancer	
  diagnosis	
  can	
  be	
  scary.	
  Learn	
  more	
  about	
  
prostate	
  cancer	
  and	
  how	
  we	
  can	
  help.	
  
	
  
Please	
  note:	
  We	
  encourage	
  consumers	
  to	
  thoroughly	
  review	
  and	
  understand	
  all	
  treatment	
  op8ons.	
  
The	
  informa8on	
  presented	
  here	
  is	
  not	
  all-­‐inclusive.	
  Rather,	
  it	
  represents	
  a	
  star8ng	
  point	
  to	
  learn	
  
more	
  about	
  medical	
  condi8ons	
  and	
  treatment	
  op8ons.	
  There	
  is	
  no	
  subs,tute	
  for	
  consul,ng	
  a	
  
medical	
  professional.	
  
529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
About	
  Prostate	
  Cancer	
  
The	
  prostate	
  is	
  a	
  walnut-­‐shaped	
  organ	
  in	
  a	
  man’s	
  lower	
  
abdomen	
  that	
  controls	
  the	
  flow	
  of	
  urine	
  and	
  semen	
  
through	
  the	
  penis.	
  Prostate	
  cancer	
  is	
  among	
  the	
  leading	
  
causes	
  of	
  cancer	
  death	
  among	
  American	
  men,	
  second	
  
only	
  to	
  lung	
  cancer.	
  	
  
	
  
Risk	
  factors:	
  
There	
  is	
  no	
  single	
  cause	
  of	
  prostate	
  cancer,	
  though	
  there	
  
are	
  several	
  known	
  risk	
  factors:	
  
	
  
•  Age	
  –	
  Risks	
  generally	
  increase	
  for	
  older	
  men.	
  
•  Race	
  –	
  African-­‐American	
  men	
  have	
  a	
  higher	
  risk	
  for	
  
unknown	
  reasons.	
  
•  NaBonality	
  –	
  Asian	
  men,	
  for	
  example,	
  have	
  a	
  lower	
  
risk.	
  
•  Diet	
  –	
  Red	
  meat	
  and	
  dairy	
  products	
  tend	
  to	
  
increase	
  risk.	
  Several	
  studies	
  suggest	
  that	
  some	
  
dietary	
  supplements	
  like	
  vitamin	
  E	
  and	
  lycopene	
  
may	
  reduce	
  risk.	
  
•  Lack	
  of	
  exercise	
  
•  Family	
  history	
  of	
  prostate	
  cancer	
  
	
  
529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
•  Early-­‐stage	
  prostate	
  cancer	
  usually	
  has	
  no	
  symptoms.	
  Older	
  men	
  may	
  experience	
  frequent	
  urinaHon,	
  
though	
  it’s	
  likely	
  due	
  to	
  an	
  enlarged	
  prostate	
  in	
  a	
  condiHon	
  known	
  as	
  benign	
  prostaHc	
  hypertrophy,	
  or	
  
BPH.	
  Pain	
  or	
  bleeding	
  is	
  not	
  commonly	
  associated	
  with	
  early	
  stages.	
  
	
  
•  Prostate	
  cancer	
  is	
  suspected	
  if	
  men	
  have	
  an	
  elevated	
  level	
  of	
  a	
  substance	
  in	
  the	
  bloodstream	
  known	
  
as	
  prostate	
  specific	
  anHgen	
  (PSA),	
  or	
  if	
  they	
  have	
  an	
  abnormality	
  like	
  a	
  nodule	
  found	
  during	
  a	
  digital	
  
rectal	
  examinaHon.	
  A	
  prostate	
  cancer	
  diagnosis	
  is	
  confirmed,	
  however,	
  only	
  through	
  biopsy.	
  
	
  
•  Urologists	
  usually	
  perform	
  biopsies	
  as	
  an	
  outpaHent	
  procedure.	
  An	
  ultrasound	
  probe	
  is	
  used	
  to	
  guide	
  
a	
  needle	
  that	
  removes	
  10	
  to	
  12	
  small	
  Hssue	
  samples	
  from	
  different	
  parts	
  of	
  the	
  prostate	
  gland.	
  
SomeHmes,	
  addiHonal	
  diagnosHc	
  tests	
  like	
  a	
  bone	
  scan,	
  CT	
  or	
  MRI	
  are	
  performed,	
  depending	
  on	
  the	
  
specific	
  diagnosis.	
  
What	
  are	
  symptoms	
  of	
  prostate	
  cancer?	
  
529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
How	
  does	
  CyberKnife	
  treat	
  prostate	
  
cancer?	
  
Prior	
  to	
  stereotacHc	
  body	
  radiosurgery	
  treatment	
  
with	
  CyberKnife,	
  small	
  Hssue	
  markers	
  known	
  as	
  
fiducials	
  are	
  implanted	
  in	
  the	
  prostate	
  to	
  help	
  the	
  
CyberKnife	
  pinpoint	
  the	
  tumor	
  locaHon	
  
throughout	
  each	
  treatment,	
  so	
  the	
  radiaHon	
  
beams	
  can	
  be	
  locked	
  on	
  the	
  tumor.	
  	
  
	
  
About	
  a	
  week	
  later,	
  paHents	
  are	
  fiWed	
  with	
  a	
  
custom	
  body	
  mold	
  of	
  soX	
  material	
  that	
  they	
  lie	
  on	
  
during	
  treatments.	
  The	
  fiYng	
  process	
  is	
  painless.	
  
	
  
The	
  treatment	
  process	
  includes:	
  
I.  ConsultaHon	
  appointment	
  
II.  Pretreatment	
  procedures	
  
III.  CyberKnife	
  treatment	
  
IV.  Follow-­‐up	
  
529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
ConsultaBon	
  and	
  Pretreatment	
  Procedures	
  
Louisville	
  CyberKnife	
  physicians,	
  therapists	
  and	
  nurses	
  are	
  focused	
  on	
  your	
  individualized	
  
treatment	
  plan:	
  
	
  
•  You	
  will	
  meet	
  a	
  Louisville	
  CyberKnife	
  radiaHon	
  oncologist	
  to	
  decide	
  if	
  CyberKnife	
  
treatment	
  is	
  appropriate	
  for	
  your	
  diagnosis.	
  	
  
	
  
•  Your	
  CyberKnife	
  team	
  will	
  decide	
  which	
  pretreatment	
  procedures	
  you	
  may	
  need	
  to	
  
help	
  develop	
  your	
  treatment	
  plan.	
  These	
  could	
  include	
  a	
  CT	
  scan,	
  an	
  MRI,	
  laboratory	
  
studies	
  or	
  Hssue	
  markers.	
  	
  
	
  
•  The	
  data	
  from	
  your	
  pretreatment	
  procedures	
  will	
  be	
  used	
  by	
  the	
  CyberKnife	
  team	
  to	
  
determine	
  the	
  exact	
  size,	
  shape	
  and	
  locaHon	
  of	
  your	
  tumor.	
  
•  This	
  informaHon	
  will	
  indicate	
  the	
  size	
  of	
  the	
  area	
  being	
  treated	
  with	
  radiaHon,	
  the	
  
radiaHon	
  dose	
  and	
  criHcal	
  structures	
  where	
  radiaHon	
  exposure	
  should	
  be	
  minimized.	
  
	
  
529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
CyberKnife	
  Treatment	
  
Typically	
  treatment	
  is	
  completed	
  within	
  five	
  
sessions.	
  On	
  the	
  day	
  of	
  your	
  treatment:	
  	
  
	
  
1.  A	
  therapist	
  will	
  help	
  you	
  onto	
  the	
  treatment	
  
table	
  and	
  fit	
  the	
  body	
  mold.	
  PaHents	
  are	
  
observed	
  throughout	
  the	
  treatment	
  on	
  closed-­‐
circuit	
  television,	
  and	
  they	
  can	
  pause	
  treatment	
  
at	
  any	
  Hme	
  by	
  waving	
  or	
  speaking	
  to	
  the	
  
technicians.	
  
2.  While	
  the	
  CyberKnife’s	
  advanced	
  tracking	
  
system	
  accounts	
  for	
  movements	
  like	
  breathing,	
  
you’re	
  asked	
  to	
  lie	
  sHll	
  during	
  treatments.	
  The	
  
system	
  periodically	
  takes	
  x-­‐ray	
  images	
  and	
  
compares	
  them	
  to	
  the	
  CT	
  scan	
  data	
  to	
  make	
  
sure	
  the	
  radiaHon	
  beam	
  is	
  locked	
  on	
  the	
  tumor.	
  
3.  PaHents	
  can	
  usually	
  return	
  to	
  their	
  normal	
  
rouHnes	
  once	
  the	
  treatment	
  is	
  complete.	
  
FOR	
  YOUR	
  INFORMATION	
  
•  Treatment	
  procedures	
  take	
  about	
  30	
  –	
  90	
  
minutes,	
  depending	
  on	
  the	
  complexity	
  of	
  your	
  
tumor.	
  
•  PaHents	
  are	
  asked	
  to	
  wear	
  comfortable	
  clothing	
  
during	
  CyberKnife	
  treatments.	
  Jewelry	
  is	
  
acceptable	
  unless	
  it	
  is	
  close	
  to	
  the	
  area	
  being	
  
treated.	
  
•  Feel	
  free	
  to	
  bring	
  an	
  iPod®	
  or	
  your	
  favorite	
  
music	
  CDs	
  with	
  you	
  on	
  the	
  day	
  of	
  your	
  
treatment,	
  and	
  we	
  will	
  play	
  them	
  for	
  you	
  during	
  
the	
  procedure.	
  
529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
AddiBonal	
  Resources	
  
529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
Our Center
Louisville	
  CyberKnife	
  is	
  part	
  of	
  the	
  renowned	
  James	
  Graham	
  Brown	
  Cancer	
  Center,	
  home	
  of	
  the	
  first	
  naHonally	
  
accredited	
  radiaHon	
  oncology	
  program	
  in	
  Louisville.	
  The	
  Brown	
  Cancer	
  Center	
  is	
  a	
  partner	
  of	
  KentuckyOne	
  Health,	
  
an	
  integrated	
  comprehensive	
  health	
  system	
  offering	
  nearly	
  200	
  locaHons	
  across	
  the	
  state	
  of	
  Kentucky	
  and	
  southern	
  
Indiana.	
  
	
  
If	
  you	
  or	
  a	
  loved	
  one	
  is	
  diagnosed	
  with	
  prostate	
  cancer,	
  contact	
  Louisville	
  CyberKnife	
  to	
  schedule	
  a	
  consultaHon	
  
with	
  our	
  physicians	
  to	
  determine	
  the	
  best	
  next	
  step	
  for	
  your	
  treatment	
  needs.	
  
	
  
	
  
Connect	
  with	
  us	
  
	
  
529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
Medical	
  Director:	
  Shiao	
  Woo,	
  M.D.,	
  M.B.B.S.	
  F.A.C.R.	
  
RadiaBon	
  Oncologist:	
  Moataz	
  El-­‐Ghamry,	
  M.D.	
  
RadiaBon	
  Oncologist:	
  Anthony	
  E.	
  Dragun,	
  M.D.	
  
RadiaBon	
  Oncologist:	
  Neal	
  E.	
  Dunlap,	
  M.D.	
  
CyberKnife	
  Nurse	
  Manager:	
  Anna	
  Murphy,	
  RN	
  

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Prostate Cancer: CyberKnife® Treatment Overview

  • 1. 529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
  • 2. September  is  Prostate  Cancer  Awareness  Month!       A  prostate  cancer  diagnosis  can  be  scary.  Learn  more  about   prostate  cancer  and  how  we  can  help.     Please  note:  We  encourage  consumers  to  thoroughly  review  and  understand  all  treatment  op8ons.   The  informa8on  presented  here  is  not  all-­‐inclusive.  Rather,  it  represents  a  star8ng  point  to  learn   more  about  medical  condi8ons  and  treatment  op8ons.  There  is  no  subs,tute  for  consul,ng  a   medical  professional.   529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
  • 3. 529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
  • 4. About  Prostate  Cancer   The  prostate  is  a  walnut-­‐shaped  organ  in  a  man’s  lower   abdomen  that  controls  the  flow  of  urine  and  semen   through  the  penis.  Prostate  cancer  is  among  the  leading   causes  of  cancer  death  among  American  men,  second   only  to  lung  cancer.       Risk  factors:   There  is  no  single  cause  of  prostate  cancer,  though  there   are  several  known  risk  factors:     •  Age  –  Risks  generally  increase  for  older  men.   •  Race  –  African-­‐American  men  have  a  higher  risk  for   unknown  reasons.   •  NaBonality  –  Asian  men,  for  example,  have  a  lower   risk.   •  Diet  –  Red  meat  and  dairy  products  tend  to   increase  risk.  Several  studies  suggest  that  some   dietary  supplements  like  vitamin  E  and  lycopene   may  reduce  risk.   •  Lack  of  exercise   •  Family  history  of  prostate  cancer     529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
  • 5. •  Early-­‐stage  prostate  cancer  usually  has  no  symptoms.  Older  men  may  experience  frequent  urinaHon,   though  it’s  likely  due  to  an  enlarged  prostate  in  a  condiHon  known  as  benign  prostaHc  hypertrophy,  or   BPH.  Pain  or  bleeding  is  not  commonly  associated  with  early  stages.     •  Prostate  cancer  is  suspected  if  men  have  an  elevated  level  of  a  substance  in  the  bloodstream  known   as  prostate  specific  anHgen  (PSA),  or  if  they  have  an  abnormality  like  a  nodule  found  during  a  digital   rectal  examinaHon.  A  prostate  cancer  diagnosis  is  confirmed,  however,  only  through  biopsy.     •  Urologists  usually  perform  biopsies  as  an  outpaHent  procedure.  An  ultrasound  probe  is  used  to  guide   a  needle  that  removes  10  to  12  small  Hssue  samples  from  different  parts  of  the  prostate  gland.   SomeHmes,  addiHonal  diagnosHc  tests  like  a  bone  scan,  CT  or  MRI  are  performed,  depending  on  the   specific  diagnosis.   What  are  symptoms  of  prostate  cancer?   529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
  • 6. 529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
  • 7. How  does  CyberKnife  treat  prostate   cancer?   Prior  to  stereotacHc  body  radiosurgery  treatment   with  CyberKnife,  small  Hssue  markers  known  as   fiducials  are  implanted  in  the  prostate  to  help  the   CyberKnife  pinpoint  the  tumor  locaHon   throughout  each  treatment,  so  the  radiaHon   beams  can  be  locked  on  the  tumor.       About  a  week  later,  paHents  are  fiWed  with  a   custom  body  mold  of  soX  material  that  they  lie  on   during  treatments.  The  fiYng  process  is  painless.     The  treatment  process  includes:   I.  ConsultaHon  appointment   II.  Pretreatment  procedures   III.  CyberKnife  treatment   IV.  Follow-­‐up   529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
  • 8. ConsultaBon  and  Pretreatment  Procedures   Louisville  CyberKnife  physicians,  therapists  and  nurses  are  focused  on  your  individualized   treatment  plan:     •  You  will  meet  a  Louisville  CyberKnife  radiaHon  oncologist  to  decide  if  CyberKnife   treatment  is  appropriate  for  your  diagnosis.       •  Your  CyberKnife  team  will  decide  which  pretreatment  procedures  you  may  need  to   help  develop  your  treatment  plan.  These  could  include  a  CT  scan,  an  MRI,  laboratory   studies  or  Hssue  markers.       •  The  data  from  your  pretreatment  procedures  will  be  used  by  the  CyberKnife  team  to   determine  the  exact  size,  shape  and  locaHon  of  your  tumor.   •  This  informaHon  will  indicate  the  size  of  the  area  being  treated  with  radiaHon,  the   radiaHon  dose  and  criHcal  structures  where  radiaHon  exposure  should  be  minimized.     529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
  • 9. CyberKnife  Treatment   Typically  treatment  is  completed  within  five   sessions.  On  the  day  of  your  treatment:       1.  A  therapist  will  help  you  onto  the  treatment   table  and  fit  the  body  mold.  PaHents  are   observed  throughout  the  treatment  on  closed-­‐ circuit  television,  and  they  can  pause  treatment   at  any  Hme  by  waving  or  speaking  to  the   technicians.   2.  While  the  CyberKnife’s  advanced  tracking   system  accounts  for  movements  like  breathing,   you’re  asked  to  lie  sHll  during  treatments.  The   system  periodically  takes  x-­‐ray  images  and   compares  them  to  the  CT  scan  data  to  make   sure  the  radiaHon  beam  is  locked  on  the  tumor.   3.  PaHents  can  usually  return  to  their  normal   rouHnes  once  the  treatment  is  complete.   FOR  YOUR  INFORMATION   •  Treatment  procedures  take  about  30  –  90   minutes,  depending  on  the  complexity  of  your   tumor.   •  PaHents  are  asked  to  wear  comfortable  clothing   during  CyberKnife  treatments.  Jewelry  is   acceptable  unless  it  is  close  to  the  area  being   treated.   •  Feel  free  to  bring  an  iPod®  or  your  favorite   music  CDs  with  you  on  the  day  of  your   treatment,  and  we  will  play  them  for  you  during   the  procedure.   529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
  • 10. AddiBonal  Resources   529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com
  • 11. Our Center Louisville  CyberKnife  is  part  of  the  renowned  James  Graham  Brown  Cancer  Center,  home  of  the  first  naHonally   accredited  radiaHon  oncology  program  in  Louisville.  The  Brown  Cancer  Center  is  a  partner  of  KentuckyOne  Health,   an  integrated  comprehensive  health  system  offering  nearly  200  locaHons  across  the  state  of  Kentucky  and  southern   Indiana.     If  you  or  a  loved  one  is  diagnosed  with  prostate  cancer,  contact  Louisville  CyberKnife  to  schedule  a  consultaHon   with  our  physicians  to  determine  the  best  next  step  for  your  treatment  needs.       Connect  with  us     529 S. Jackson Street, Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com Medical  Director:  Shiao  Woo,  M.D.,  M.B.B.S.  F.A.C.R.   RadiaBon  Oncologist:  Moataz  El-­‐Ghamry,  M.D.   RadiaBon  Oncologist:  Anthony  E.  Dragun,  M.D.   RadiaBon  Oncologist:  Neal  E.  Dunlap,  M.D.   CyberKnife  Nurse  Manager:  Anna  Murphy,  RN