15th International Conference on Intelligent Systems for Molecular Biology, Austria Center Vienna, Vienna, Austria, July 22-25, 2007

1. Just-in-time assembly Co-evolution of transcriptional and post-translational cell-cycle regulation of protein complexes Lars Juhl Jensen EMBL Heidelberg

2. the cell cycle

3. grow and divide

4. one cell

5. two cells

6. four phases

7. G 1 phase

8. growth

9. S phase

10. DNA replication

11. G 2 phase

12. growth

13. M phase

14. cell division

16. regulation

17. transcription

18. interactions

19. phosphorylation

20. targeted degradation

21. S. cerevisiae

22. Cho et al.

23. Spellman et al.

24. microarrays

26. expression profiles

28. computational methods

29. Spellman et al.

30. Zhao et al.

31. Langmead et al.

32. Johansson et al.

33. Wichert et al.

34. Luan and Li

35. Lu et al.

36. Ahdesm äki et al.

37. Willbrand et al.

38. Chen

39. Qiu et al.

40. Ahnert et al.

41. Glynn et al.

42. Andersson et al.

43. Lu et al.

44. Xu et al.

45. Liew et al.

46. no benchmarking

47. reanalysis

48. benchmarking

50. no progress

51. cross-species comparison

52. reanalysis

53. S. pombe

54. H. sapiens

55. A. thaliana

56. 400–600 periodic genes

57. four organisms

58. orthologous groups

60. not conserved

61. protein interactions

62. expression data

63. temporal network

65. dynamic and static subunits

66. just-in-time assembly

68. evolutionary flexibility

69. different organisms

70. different dynamic subunits

71. cross-species comparison

72. protein complexes

76. different time scales

77. time warping

79. DNA polymerases

81. different organisms

82. different dynamic subunits

83. time of peak expression

84. time of action

86. phosphorylation

87. Übersax et al.

88. Loog et al.

89. Phospho.ELM

90. NetPhosK

91. correlation

93. Fisher’s exact test

94. statistically significant

95. trivial

96. correlated changes

98. Fisher’s exact test

99. statistically significant

100. co-evolution

101. transcriptional regulation

102. phosphorylation

103. targeted degradation

104. just-in-time assembly

107. C1