1.
How Plants Avoid Sunburn: Findings Could Lead to
Crops With Increased Protection from Bright Light and
Enhanced Photosynthesis and- Cell Memory
Mechanism Discovered
[(Science Daily (Aug. 6, 2013)- Science daily (Aug. 15, 2013 )]
Carolina Carvajal Miranda
Medicine Student
Universidad Pontificia Bolivariana
Medellín

2.
FOLDING
MARTINEZ S., Lina Maria. Biologia molecular. 5. ed. Medellin: UPB.
Fac. de Medicina,
2009.265 p.
 How Plants Avoid Sunburn: Findings Could Lead to Crops With
Increased Protection from Bright Light and Enhanced Photosynthesis
-Science Daily- (Aug. 6, 2013) H.-S. Jung, P. A. Crisp, G. M. Estavillo, B.
Cole, F. Hong, T. C. Mockler, B. J. Pogson, J. Chory. Subset of heat-
shock transcription factors required for the early response of
Arabidopsis to excess light. Proceedings of the National Academy of
Sciences, 2013;
Cell Memory Mechanism Discovered Science daily (Aug. 15, 2013 )-
ScienceDaily- Jian Yan, Martin Enge, Thomas Whitington, Kashyap
Dave, Jianping Liu, Inderpreet Sur, Bernhard Schmierer, Arttu Jolma,
Teemu Kivioja, Minna Taipale, Jussi Taipale. Transcription Factor
Binding in Human Cells Occurs in Dense Clusters Formed around
Cohesin Anchor Sites.

3.
FOLDING

4.
Stress-related proteins
explain how plants avoid
sunburn in intense light.
Mechanism for cellular
memory:COHESIN
INTRODUCTION

5.
How Plants Avoid Sunburn: Findings Could Lead to
Crops With Increased Protection from Bright Light and
Enhanced Photosynthesis
Science Daily (Aug. 6, 2013)

6.
How Plants Avoid Sunburn: Findings Could Lead to
Crops With Increased Protection from Bright Light and
Enhanced Photosynthesis
 Quantity and fluctuation of light
conditions cause stress to plants.
 Transcription Factors are
responsible for fast response to
changes in light.

7.
How Plants Avoid Sunburn: Findings Could Lead to
Crops With Increased Protection from Bright Light and
Enhanced Photosynthesis
 Regulation in nuclear gene expression and intracellular signaling
pathways genomic response to stress
 Enzyme detoxifies harmful molecules, which accumulate under very
bright light.

8.
How Plants Avoid Sunburn: Findings Could Lead to
Crops With Increased Protection from Bright Light and
Enhanced Photosynthesis
 Study of short-term and long-term
response factors
Generate plants with
increased protection
from light and
enhanced
photosynthesis.

9.
OBSERVATION
In my opinion the importance of this study
is directly implicated in the capacity of this
organism to eliminate harmful sustances.
Future investigations should be centered on
the nuclear regulation of gene expressions.
I also consider, the posibility of applying
this knowlege in the therapeutic field.

10.
Cell Memory Mechanism
Discovered
Science daily (Aug. 15, 2013 )

11.
Cell Memory Mechanism
Discovered
Regulatory DNA
sequences
Transcription
factors
Binds to
sequences
 Expresion of
proteins
It is critical that the pattern of transcription factor binding in
the genome be maintained.

12.
Cell Memory Mechanism
Discovered
 Transcription factors find original binding region on DNA strands.
 large protein complex positioned as a ring around the
two DNA strands
Marks places where
transcription factors
were bound.
Indicator of
sequences that
contain mutations
COHESIN:

13.
Cell Memory Mechanism
Discovered

14.
Cell Memory Mechanism
Discovered
 Complete map of transcription factors
 Analisis of DNA sequences that bind to cohesin:
Mutations

15.
Cell Memory Mechanism
Discovered
Analyse DNA sequences that are located in genes
(3% of genome)
DNA sequences that bind to cohesin(1% of genome).
Most Mutations (Cancer) are outside genes.

16.
OBSERVATION
I think this research has an important
impact in the biological study of the
genome, I consider the cohesin to be a
crucial marker in the transcription of
specific secuences that can be monitor
to explain certain mutations, as well, it
plays an important role to create a new
investigation base that can be used to
develop future therapys in hereditary
conditions.

17.
MEDICAL UTILITY

18.
MEDICAL UTILITY
How Plants Avoid Sunburn: Findings Could Lead to Crops With
Increased Protection from Bright Light and Enhanced
Photosynthesis
Generation of plants with increased
protection from light with enhanced
photosynthesis rates that benefit
population by decreasing air
contamination.

19.
MEDICAL UTILITY
Cell Memory Mechanism Discovered
Facilitate the identification and
analysis of specific mutations, and in
future view, bring hope for cancer
and hereditary deseased patients.

20.
BIBLIOGRAPHY
 MARTINEZ S., Lina Maria. Biologia molecular. 5. ed. Medellin: UPB. Fac. de Medicina,
2009.265 p.
 How Plants Avoid Sunburn: Findings Could Lead to Crops With Increased Protection from Bright
Light and Enhanced Photosynthesis -Science Daily- (Aug. 6, 2013) H.-S. Jung, P. A. Crisp, G. M.
Estavillo, B. Cole, F. Hong, T. C. Mockler, B. J. Pogson, J. Chory. Subset of heat-shock
transcription factors required for the early response of Arabidopsis to excess light.
Proceedings of the National Academy of Sciences, 2013; DOI:
 Cell Memory Mechanism Discovered Science daily (Aug. 15, 2013 )-ScienceDaily- Jian Yan,
Martin Enge, Thomas Whitington, Kashyap Dave, Jianping Liu, Inderpreet Sur, Bernhard
Schmierer, Arttu Jolma, Teemu Kivioja, Minna Taipale, Jussi Taipale. Transcription Factor
Binding in Human Cells Occurs in Dense Clusters Formed around Cohesin Anchor Sites.
Cell, 2013; 154 (4): 801 DOI: