A brief outlook to uveitis and its its management.

1. UVEITISUVEITIS

2. UVEITIS
Inflammation of the middle vascular coat
or
uvea of the eye is called uveitis.

3. Types of the uveitis
 Anterior uveitis
–Iritis
–Iridocyclitis
 Intermediate uveitis
 Posterior uveitis
–Retinitis
–Choroiditis
–Retinochoroiditis/
chorioretinitis
 Panuveitis
Depending on the location of inflammation

4. Types
Depending on the onset and duration of the
disease.
• Acute
• Recurrent
• Chronic

5. Types
Depending on the clinical picture.
» Granulomatous
» Non-granulomatous

6. Etiology of uveitis
 Infections
• Bacterial
• Viral
• Fungal
• Parasitic
• Spirochaetal
 Arthritis related
 Trauma
 Collagen vascular diseases
 Idiopathic

7. Anterior uveitis
» Iritis
» Iridocyclitis

8. Symptoms
» Pain
» Redness
» Photophobia
» Diminution of vision

9. Examination
– Circum corneal congestion (CCC).
– Keratic precipitates (K.P.)
– Flare in A/C.
– Cells in A/C.
– Hypopyon.
– Muddy iris.
– Iris nodules.
– Iris atrophy and loss of pattern.

10. Circum corneal congestion (CCC)

11. Hypopyon

12. Keratic precipitates (KPs)
Fine to medium size KPs Mutton Fat KPs

14. Pupil
» Usually constricted
» May be irregular
» Posterior synechiae
» Seclusio pupillae
» Occlusio pupillae

15. Pupillary membrane (Occlusio pupillae) with 360 posterior
synechia

16. Seclussio pupillae

17. Posterior Synechia

18. Iris atrophy

19. Iris nodules
Koeppe’s nodules Bussaca’s nodules

20. Lens
– Pigments on the lens surface.
– Cataractous changes in the lens.

22. Posterior subcapsular cataract

23. Vitreous
» Cells
» Opacities

25. Fundus
• Usually unremarkable but macular
edema can be present in anterior
uveitis too.

26. Cystoid Macular Edema

27. Complications
• Band keratopathy
• Glaucoma
• Cataract
• Macular edema
• Phthisis bulbi

28. Band keratopathy

29. Investigations
• Depending on clinical picture
• For infections
• Rheumatoid factor
• ANA
• HLA typing
• Tests for syphilis
• Screen for HIV in selected cases

30. Treatment
– Topical Mydriatic- cycloplegic
– Topical corticosteroid
– Periocular corticosteroid injection
– Systemic corticosteroids
– Cyclosporins
– Cytotoxic agents.
– Treatment of the underlying causes

31. THANK YOU.