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Beyond Scaling Up
  Universal Access to Effective
Malaria Prevention and Treatment:
      how do we get there?

                  Sunil Mehra
        Executive Director, Malaria Consortium
                 with contributions from
 Dr. Albert Kilian, Dr. Sylvia Meek, Dr. Graham Root,
                 and Caroline Vanderick
MALARIA - Introduction
          Malaria control rests on two major pillars

   Case                                               Prevention
Management

Treatment                                                LLIN
               Parasite                  Vector
                          Environment
   IPTp                                                  IRS
                              Host
                                                      Environmetal
   IPTi                                               Management




 Within the prevention arm Long-Lasting Insecticidal Nets (LLIN)
   form the most important intervention in sub-Saharan Africa
Prevention with LLIN
    For many years the RBM Working Group on ITN (now Vector
    Control WG) has suggested a mixed model approach to scaling
    up ITN
    However, actual implementation did not take off due to lack of
    donor commitment 2003-05
 2003
                         Unsubsidized commercial expansion for sustainability


Short term subsidies to encourage ITN market growth

                Long term targeted subsidies for most vulnerable

                                                            Domestic funding

Donor funding

   2010
                                   Time
Saving Lives,
Sustaining Gains
Nigeria: Support to the National Malaria Programme
                 CNTR 2007 07843

           Malaria Consortium Partnership
                       2006
Our Vision
 Vulnerable groups are protected with LLINs and access
 effective treatment through public and private channels.

Informed households, including poor, demand for and can
             obtain free or affordable LLINs

    Increased demand encourages many suppliers,
 competition keeps prices low; and rural and community-
           based distribution systems expand.

        The burden of malaria declines especially
                  amongst the poor.
Public Health,
Private Markets
   Approach
Public Health Private Markets
     Aiming for sustained total coverage
                Each sector has unique strengths
All contribute to public health, none alone can achieve total coverage


  Public Sector
                            Civil Society         Commercial Sector
Improving delivery
of health services,       Focus on the poor         Improving access
 setting policies,        and marginalised        through competition
   stewardship



Public health private markets extends the potential of each sector
          through an inclusive and pluralistic approach
Balance of components
 Creation of sustainable demand & supply across all populations


   Public and civil society
                                    Commercial sector support
     sector component
Ensures equity and targeting
4.4 million free LLINs through
campaigns                           Mass market response and
Achieves rapid results
SMoH supported to distribute        lower pricing leads to long-term
                                    10 million subsidised LLINs
5 million LLINs through ANC
Helps open up mass market           sustainability
                                    through commercial sector
demand of care improved in
Quality                             9.5 million subsidised <5yrs
6,500 health facilities             ACTs at 10 cents each
30 million doses of SP for IPT
provided


   Key strategy: demand creation and a blended
   distribution system for sustained and equitable
                       impact
Attaining and Sustaining
        Coverage
The Evidence from Kenya
            Reviewed three different distribution models
1.   Traditional social marketing model by PSI
2.   Health facility based distribution of subsidised nets ($0.70)
3.   Campaign distribution of free ITNs to under-fives

                        Two key findings
1.   Only campaigns able to reach high coverage levels quickly
2.   Campaigns can reach the poor


     DFID five year support to ITN social marketing in Kenya

1.   Had limited impact on coverage / ‘access’
2.   Impacted negatively on the real commercial sector
MCP Approach to Coverage
• Kenya data confirms a key element of the MCP
  approach – campaigns are necessary

• MCP recognises that a mixed model is essential to not
  only rapidly increase coverage but also to sustain it
• Rapid increase
   – Free campaigns
• Sustain high coverage
   – Routine free distribution through ANC and health facilities
   – Improved access to LLINs through the commercial sector at
     an affordable price
Malaria Consortium
   Sustaining LLIN/ITN Targets Model
• Developed by Malaria Consortium M&E and Research
  Department
• Model estimates required inputs to attain and sustain
  coverage levels for LLIN/ITNs
• Model validated against real data from our Uganda
  and Mozambique programmes
• Currently being used by RBM partners
• RBM adopted our model to forecast LLIN/ITN needs
  across Africa
Malaria Consortium Sustaining LLIN Targets Model
                                                  Dynamic Loss Function
                                       100%
     Proportion of nets still in use   90%
                                                                                    Polyethylene
                                       80%
                                                                                    Polyester
                                       70%
                                       60%
                                       50%
                                       40%
                                       30%
                                       20%
                                       10%
                                        0%
                                              0   2   4   6      8    10       12      14       16   18
                                                              Tim e in years
Nigeria: total expected net output in 12
                project states
             4,500,000

             4,000,000

             3,500,000

             3,000,000
Net output




                                                campaign
             2,500,000
                                                routine
                                                LLIN subsidy
             2,000,000
                                                unsubsidized

             1,500,000

             1,000,000

              500,000

                    0
                         1   2    3     4   5
                                 Year
Nigeria – 12 project states
                                                  Campaigns children under 5
                             10,000,000                                        100.0%


                              9,000,000                                        90.0%




                                                                                        Proportion of hh with at least one net in %
                              8,000,000                                        80.0%
Number of nets distributed




                              7,000,000                                        70.0%


                              6,000,000                                        60.0%
                                                                                                                                      total net output
                              5,000,000                                        50.0%                                                  commercial
                                                                                                                                      ITN coverage
                              4,000,000                                        40.0%


                              3,000,000                                        30.0%


                              2,000,000                                        20.0%


                              1,000,000                                        10.0%


                                     0                                         0.0%
                                          0   1       2          3   4     5
                                                          Year
Nigeria – 12 project states
                                              Campaigns children under 5 + ANC
                             10,000,000                                          100.0%


                              9,000,000                                          90.0%




                                                                                          Proportion of hh with at least one net in %
                              8,000,000                                          80.0%
Number of nets distributed




                              7,000,000                                          70.0%


                              6,000,000                                          60.0%
                                                                                                                                        total net output
                              5,000,000                                          50.0%                                                  commercial
                                                                                                                                        ITN coverage
                              4,000,000                                          40.0%


                              3,000,000                                          30.0%


                              2,000,000                                          20.0%


                              1,000,000                                          10.0%


                                     0                                           0.0%
                                          0   1      2          3   4      5
                                                         Year
Nigeria – 12 project states
                                          Campaigns children under 5 + ANC + commercial subsidy
                             10,000,000                                               100.0%


                              9,000,000                                               90.0%




                                                                                               Proportion of hh with at least one net in %
                              8,000,000                                               80.0%
Number of nets distributed




                              7,000,000                                               70.0%


                              6,000,000                                               60.0%
                                                                                                                                             total net output
                              5,000,000                                               50.0%                                                  commercial
                                                                                                                                             ITN coverage
                              4,000,000                                               40.0%


                              3,000,000                                               30.0%


                              2,000,000                                               20.0%


                              1,000,000                                               10.0%


                                     0                                                0.0%
                                             0      1      2          3   4      5
                                                               Year
Nigeria – 12 project states
                             Campaigns children under 5 + ANC + commercial subsidy + unsubsidized
                             10,000,000                                          100.0%


                              9,000,000                                          90.0%




                                                                                          Proportion of hh with at least one net in %
                              8,000,000                                          80.0%
Number of nets distributed




                              7,000,000                                          70.0%


                              6,000,000                                          60.0%
                                                                                                                                        total net output
                              5,000,000                                          50.0%                                                  commercial
                                                                                                                                        ITN coverage
                              4,000,000                                          40.0%


                              3,000,000                                          30.0%


                              2,000,000                                          20.0%


                              1,000,000                                          10.0%


                                     0                                           0.0%
                                          0   1       2          3   4      5
                                                          Year
Sustaining LLIN/ITN
  Targets Model
Uganda: modelling scenarios of distribution
         Campaign distributions to all U5 & PW every 5 years, 50% polyethylene, 50% polyester

                             10,000,000                                                                                     100.0%
                              9,500,000
                              9,000,000                                                                                     90.0%




                                                                                                                                     Proportion of hh with at least one net in %
                              8,500,000
                              8,000,000                                                                                     80.0%
                              7,500,000
Number of nets distributed




                              7,000,000                                                                                     70.0%
                                                                    DHS
                              6,500,000                             2006
                              6,000,000                                                                                     60.0%
                                                                    15.9%
                              5,500,000                                                                                                                                            actual distribution
                              5,000,000                                                                                     50.0%                                                  projected
                              4,500,000                                                                                                                                            ITN coverage
                              4,000,000                                                                                     40.0%
                              3,500,000       DHS
                                              2000/01
                              3,000,000                                                                                     30.0%
                              2,500,000       1.6%
                              2,000,000                                                                                     20.0%
                              1,500,000
                              1,000,000                                                                                     10.0%
                               500,000
                                     0                                                                                      0.0%
                                          2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
                                                                              Year
Uganda: modelling scenarios of distribution
                             Initial campaign U5 & PW then 80% of PW-ANC, 50% polyethylene, 50% polyester

                             10,000,000                                                                                     100.0%
                              9,500,000
                              9,000,000                                                                                     90.0%




                                                                                                                                     Proportion of hh with at least one net in %
                              8,500,000
                              8,000,000                                                                                     80.0%
                              7,500,000
Number of nets distributed




                              7,000,000                                                                                     70.0%
                              6,500,000
                              6,000,000                                                                                     60.0%
                              5,500,000                                                                                                                                            actual distribution
                              5,000,000                                                                                     50.0%                                                  projected
                              4,500,000                                                                                                                                            ITN coverage
                              4,000,000                                                                                     40.0%
                              3,500,000
                              3,000,000                                                                                     30.0%
                              2,500,000
                              2,000,000                                                                                     20.0%
                              1,500,000
                              1,000,000                                                                                     10.0%
                               500,000
                                     0                                                                                      0.0%
                                          2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
                                                                              Year
Uganda: modelling scenarios of distribution
                                 Initial campaign U5 & PW then 80% of PW-ANC plus 25% of households buy,
                                                       50% polyethylene, 50% polyester
                             10,000,000                                                                                     100.0%
                              9,500,000
                              9,000,000                                                                                     90.0%




                                                                                                                                     Proportion of hh with at least one net in %
                              8,500,000
                              8,000,000                                                                                     80.0%
                              7,500,000
Number of nets distributed




                              7,000,000                                                                                     70.0%
                              6,500,000
                              6,000,000                                                                                     60.0%
                              5,500,000                                                                                                                                            actual distribution

                              5,000,000                                                                                     50.0%                                                  projected
                              4,500,000                                                                                                                                            ITN coverage
                              4,000,000                                                                                     40.0%
                              3,500,000
                              3,000,000                                                                                     30.0%
                              2,500,000
                              2,000,000                                                                                     20.0%
                              1,500,000
                              1,000,000                                                                                     10.0%
                               500,000
                                     0                                                                                      0.0%
                                          2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
                                                                              Year
Reaching the Poor
The Evidence from Kenya




Noor et al, 2007
The Evidence from Mozambique
                                                                  100
Cumulative % of households with intervention by wealth quintile



                                                                                                                                                Equity line
                                                                  90                           Concentration Curve                              Com LLIN
                                                                                                                                                Pub LLIN
                                                                  80                                                                            SM LLIN


                                                                  70

                                                                  60
                                                                                                                                                  Equity of LLIN by
                                                                                                                                               Distribution Mechanism
                                                                  50

                                                                  40                                                                              Concentration Index
                                                                  30
                                                                                                                                                Public          -0.11
                                                                  20
                                                                                                                                                Commercial      +0.11
                                                                  10
                                                                                                                                                Social Marketing +0.42
                                                                    0
                                                                        0   10      20    30     40    50     60    70    80        90   100
                                                                                 Cumulative % of all households by wealth quitile
Reaching the Poor - Prevention
• Kenya evidence
  – Shows free campaigns are pro-poor
  – Shows inequity of single-branded social marketing
• Mozambique evidence
  – Shows free ANC and campaign distributions are
    pro-poor
  – Show reasonable equity for commercial sector
  – Shows inequity of single-branded social marketing
The reach of our partnership
                       Distribution Networks
                                      Sprin
                           l–               gfield
                    g l oba             exten      s/Af
            P atem wide                       sive c cott –
                      n       rk       farme         ot
               natio n netwo                 rs net ton
                    tio                              work
          dis tribu

               cal
         aceuti           CHAN MediPharm –
  Pharm ers – well       Depots serving all six       C.Zard – over 150
         ur
ma nufact networks              zones               retailers country-w
                                                                        ide
        red
structu

          Har
      exten vestfield –                 Rosies Textile
                                                       s–
           sive d                                   etwork
        netwo     istribu
                          tion        distribution n
              rk in s                                d Kano
                     outh             for SE, SW an
Price Support for
 Sustainability
Price Support
• Price support is channelled through the commercial
  sector
• Implementing agency does not retain the price
  support/subsidy
• Pioneering approach: done in Uganda and
  Mozambique by MC
• Price support aims to:
   –   Reduce the price of quality/qualified LLINs
   –   Increase competition and choice
   –   Extend the market reach
   –   Support the development of a viable and expanding market
Price support – does it work?

• Malaria Consortium experience in
  Mozambique and Uganda :
  – Increased commercial sector sales of LLINs
  – Increased number of brands on market
  – Reduced retail price of LLINs to compete with
    conventional untreated (and often poor quality)
    nets
  – Commercial sector sales rose at a time of mass
    free LLIN distributions
MCP commercial partners’ ITN sales,
          Mozambique
                       340,000
                       320,000
                       300,000
                       280,000               institutional
                       260,000               retail
Cumulative ITN sales




                       240,000
                       220,000
                       200,000
                       180,000
                       160,000
                       140,000
                       120,000
                       100,000
                        80,000
                        60,000
                        40,000
                        20,000
                            0
                                                                     MAY




                                                                                                                                             MAY
                                             JAN


                                                         MAR
                                                               APR




                                                                                                                     JAN


                                                                                                                                 MAR
                                                                                                                                       APR
                                                                                       AUG




                                                                                                                                                               AUG
                                                                                 JUL




                                                                                                   OCT




                                                                                                                                                         JUL




                                                                                                                                                                           OCT
                                 NOV




                                                                                             SEP


                                                                                                         NOV




                                                                                                                                                                     SEP


                                                                                                                                                                                 NOV
                                       DEC




                                                                           JUN




                                                                                                               DEC




                                                                                                                                                   JUN




                                                                                                                                                                                       DEC
                                                   FEB




                                                                                                                           FEB
                                 2005                                      2006                                                                    2007
Examples of commercial sector development
                              100.0%                                               5,000,000
                                         public and civil society
                                         social marketing
                              90.0%      commercial partners                       4,500,000
                                         estimated informal market
                                         % LLIN
                              80.0%                                                4,000,000

                              70.0%                                                3,500,000
    Proportion of nets LLIN



U




                                                                                               Total number of nets
                              60.0%                                                3,000,000
g
a                             50.0%                                                2,500,000
n
d                             40.0%                                                2,000,000
a
                              30.0%                                                1,500,000

                              20.0%                                                1,000,000

                              10.0%                                                500,000

                               0.0%                                                0
                                   1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Rapid Scale-up

Since 2005 increasing investments and since
2008 good progress in many countries
Based on modelling and practical experience
clear indication that only mass campaign style
distributions can achieve rapid scale-up
towards universal coverage
Limitations of Campaigns
                                            However, loss of nets through “wear and tear” and other behavioural
                                                                     factors starts early

                                                                Model                                                        Field data
                                 100%                                                               100%   100
                                 90%                                                                90%    90
                                 80%                                                                80%    80
Households with at least 1 ITN




                                 70%                                                                70%    70
                                 60%                                                                60%    60
                                 50%                                                                50%    50
                                 40%                                                                40%    40                                 Togo
                                 30%                                                                30%    30                                 Sofala - Moz
                                 20%                                                                20%    20                                 Manica - Moz

                                 10%                                                                10%
                                                                                                           10                                 Law ra - Ghana

                                  0%                                                                0%
                                                                                                            0
                                        0   1   2   3   4   5   6   7   8   9   10 11 12 13 14 15                0   1   2    3     4     5    6       7       8
                                                                    Years                                                         Years
Limitations of Campaigns
                                        Even repeated campaigns can not sustain high levels
                                        of coverage in an continuous fashion
                                 100%                                                                           100%

                                 90%                                                                            90%

                                 80%                                                                            80%
Households with at least 1 ITN




                                 70%                                                                            70%

                                 60%                                                                            60%

                                 50%                                                                            50%

                                 40%                                                                            40%

                                 30%                                                                            30%

                                 20%                                                                            20%

                                 10%                                                                            10%

                                  0%                                                                            0%
                                         0    1   2   3   4   5   6   7   8   9   10   11   12   13   14   15
                                                                      Years
Need for continuous distributions
Distributions are needed that supply LLIN to
target groups and/or customers in a
continuous manner over long periods of time
  To reach new families
  To replace torn, lost or destroyed nets
  To fill gaps in family demand for nets not covered
  by campaign distributions
  To satisfy demand for choice (size, shape, colour
  of nets)
Channels for continuous distributions
  Primary distribution mechanisms are
    Routine health services (ANC/EPI)
    Commercial retail market
    Unsubsidized
    Subsidized through “total market approach”


  Additionally and/or in places were neither health
  services nor the market can reach the population
  alternatives must be developed
    Through community based approaches
    Schools
    Religious institutions
Sustaining high coverage
                                        Modelling suggest that this mixed approach will sustain
                                            high coverage (emerging support from data)
                                 100%                                                                            100%

                                 90%                                                                             90%

                                 80%                                                                             80%
Households with at least 1 ITN




                                 70%                                                                             70%
                                                ANC 85% & 20% hh
                                 60%                                          ANC 85% & 40% hh                   60%

                                 50%                                                                             50%

                                 40%                                                                             40%

                                 30%                                                                             30%

                                 20%                                                                             20%
                                                Single campaign
                                 10%                                                                             10%

                                  0%                                                                             0%
                                        0   1    2   3   4   5    6   7   8    9   10   11   12   13   14   15
                                                                      Years
The role of commercial sector
Emerging data from Uganda and Nigeria seem to support this

                                                       Within 5 months of free distribution 4-9% of households
                                                       procured an additional net from the commercial market
                                                       10
 % of household buying commercial net after free net


                                                                 8.9                              ANC
                                                        9
                                                                                                  Campaign
                                                        8

                                                        7

                                                        6
                                                                          5.2
                                                        5
                                                                                                  4.0
                                                        4

                                                        3

                                                        2

                                                        1

                                                        0
                                                                   Adjumani                Kano
Some Results
Distributing LLIN
              Number of LLIN distributed by MC                                         Contribution of countries
10,000,000

                                                                           8,904,048
 9,000,000


 8,000,000


 7,000,000
                                                                                               Nigeria, 1,885,000, 21%

 6,000,000                                                     5,654,329

                                                                                                                               Uganda, 3,773,897, 43%
 5,000,000
                                                                                       Southern Sudan, 399,320, 4%

                                                                                       Sudan, 188,100, 2%
 4,000,000
                                                   3,382,287

 3,000,000
                                                                                                  Mozambique, 2,657,731, 30%

 2,000,000


 1,000,000                               657,612

             10,000   47,135   144,512
        0
             2003     2004     2005      2006       2007        2008        2009
Retention of LLIN after 6 Months
                              100


                              90


                              80
Proportion of nets retained



                              70


                              60


                              50


                              40


                              30


                              20


                              10


                               0
                                    Adjumani   Jinja     Katakwi   Kitgum   Gulu    Cabo     Inhambane   Nampula   Manica   Sofala
                                                                                   Delgado


                                                       Uganda                                    Mozambique
Equity of distribution
                                                                              Favouring the-poor
                                                        Concentration Curve                                                                                                                           Concentration Curve
                                            100
                                                      Uganda ANC and campaign                                                                                                                          Mozambique, ANC
                                                                                                                                                                                       100




                                                                                                                               Cumulative percentage of households with intervention
                                             90                                                                                                                                         90
Cumulative percentage of wealth quintiles




                                             80
 among hh with person to net ratio <=2.0




                                                                                                                                                                                        80

                                             70                                                                                                                                         70

                                             60                                                                                                                                         60

                                             50                                                                                                                                         50

                                             40                                                                                                                                         40

                                             30                                                                                                                                         30

                                             20                                                                                                                                         20
                                                                                                      equity line
                                                                                                      distribution
                                             10                                                                                                                                         10

                                              0                                                                                                                                          0
                                                  0    10       20    30     40     50    60     70     80          90   100                                                                 0   10   20   30    40    50    60    70    80   90   100
                                                            Cumulative percentage of wealth quintiles in sample                                                                                        Cumulative percentage of households
Impact of LLIN
                    Monitoring area Kamwenge, Uganda
                                    100

                                    90
Proportion with malaria parasites


                                    80                                     Increased access
                                                                           to health services
                                    70
                                                                                                    1994
                                    60                                                              1997
                                                                             ACT introduced
                                                                                                    1998
                                    50                                                              2007
                                                                                                    2008
                                    40                                       LLIN campaign

                                    30

                                    20

                                    10

                                     0
                                          0   1     2        3         4       5                6
                                                        Age in years
The New Paradigm
 • What do we mean?
   –   Global recognition of malaria problem
   –   Sufficient financing available
   –   Lofty ambitions
   –   Move from focus on burden reduction to focus on
       transmission reduction
 • What must this translate into?
   – Converted into successful malaria control
   – Particularly higher transmission countries.
        • The heartland.
Scaling up and beyond
• Aggressive promotion of single solutions
  – GFATM funding forcing policy (examples?)
  – LLIN delivery through measles campaigns
  – Home-management of malaria (one disease system)
• Toward single models for delivery
• Blunt instrument
• Some value:
  – Increase coverage quickly
  – Focus on a single delivery models for quick results
Scaling up and beyond
• Longer term thinking
• Reflect the diversity:
  – Epidemiology
  – Socio-economic settings
  – Health systems
• Grounded/centred where the problem is
• Locus: local rather than global
Heightened advocacy                          The Paradigm Shift:
   Global                                                         beyond burden,
                     Increasing pressure
 conformity
  progress                                                        towards transmission
                     2010 coverage targets

                         Si
                              ng
                   Bl            l   e
                      un            so
                         t   ,s         lu
                                          tio
                               ho            ns
                                 r t-           to
                                      te            de
                                         rm
                                            in         liv
                                              st           er
                                                 ru           y
                                                   m
                                                     en
                                                         t


Range of delivery models
  Epidemiology
  Socio-economic settings
  Health systems                                         Local diversity

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Beyond Scaling Up: Universal Access to Effective Malaria Prevention and Treatment. How do we get there?

  • 1. Beyond Scaling Up Universal Access to Effective Malaria Prevention and Treatment: how do we get there? Sunil Mehra Executive Director, Malaria Consortium with contributions from Dr. Albert Kilian, Dr. Sylvia Meek, Dr. Graham Root, and Caroline Vanderick
  • 2. MALARIA - Introduction Malaria control rests on two major pillars Case Prevention Management Treatment LLIN Parasite Vector Environment IPTp IRS Host Environmetal IPTi Management Within the prevention arm Long-Lasting Insecticidal Nets (LLIN) form the most important intervention in sub-Saharan Africa
  • 3. Prevention with LLIN For many years the RBM Working Group on ITN (now Vector Control WG) has suggested a mixed model approach to scaling up ITN However, actual implementation did not take off due to lack of donor commitment 2003-05 2003 Unsubsidized commercial expansion for sustainability Short term subsidies to encourage ITN market growth Long term targeted subsidies for most vulnerable Domestic funding Donor funding 2010 Time
  • 4. Saving Lives, Sustaining Gains Nigeria: Support to the National Malaria Programme CNTR 2007 07843 Malaria Consortium Partnership 2006
  • 5. Our Vision Vulnerable groups are protected with LLINs and access effective treatment through public and private channels. Informed households, including poor, demand for and can obtain free or affordable LLINs Increased demand encourages many suppliers, competition keeps prices low; and rural and community- based distribution systems expand. The burden of malaria declines especially amongst the poor.
  • 7. Public Health Private Markets Aiming for sustained total coverage Each sector has unique strengths All contribute to public health, none alone can achieve total coverage Public Sector Civil Society Commercial Sector Improving delivery of health services, Focus on the poor Improving access setting policies, and marginalised through competition stewardship Public health private markets extends the potential of each sector through an inclusive and pluralistic approach
  • 8. Balance of components Creation of sustainable demand & supply across all populations Public and civil society Commercial sector support sector component Ensures equity and targeting 4.4 million free LLINs through campaigns Mass market response and Achieves rapid results SMoH supported to distribute lower pricing leads to long-term 10 million subsidised LLINs 5 million LLINs through ANC Helps open up mass market sustainability through commercial sector demand of care improved in Quality 9.5 million subsidised <5yrs 6,500 health facilities ACTs at 10 cents each 30 million doses of SP for IPT provided Key strategy: demand creation and a blended distribution system for sustained and equitable impact
  • 10. The Evidence from Kenya Reviewed three different distribution models 1. Traditional social marketing model by PSI 2. Health facility based distribution of subsidised nets ($0.70) 3. Campaign distribution of free ITNs to under-fives Two key findings 1. Only campaigns able to reach high coverage levels quickly 2. Campaigns can reach the poor DFID five year support to ITN social marketing in Kenya 1. Had limited impact on coverage / ‘access’ 2. Impacted negatively on the real commercial sector
  • 11. MCP Approach to Coverage • Kenya data confirms a key element of the MCP approach – campaigns are necessary • MCP recognises that a mixed model is essential to not only rapidly increase coverage but also to sustain it • Rapid increase – Free campaigns • Sustain high coverage – Routine free distribution through ANC and health facilities – Improved access to LLINs through the commercial sector at an affordable price
  • 12. Malaria Consortium Sustaining LLIN/ITN Targets Model • Developed by Malaria Consortium M&E and Research Department • Model estimates required inputs to attain and sustain coverage levels for LLIN/ITNs • Model validated against real data from our Uganda and Mozambique programmes • Currently being used by RBM partners • RBM adopted our model to forecast LLIN/ITN needs across Africa
  • 13. Malaria Consortium Sustaining LLIN Targets Model Dynamic Loss Function 100% Proportion of nets still in use 90% Polyethylene 80% Polyester 70% 60% 50% 40% 30% 20% 10% 0% 0 2 4 6 8 10 12 14 16 18 Tim e in years
  • 14. Nigeria: total expected net output in 12 project states 4,500,000 4,000,000 3,500,000 3,000,000 Net output campaign 2,500,000 routine LLIN subsidy 2,000,000 unsubsidized 1,500,000 1,000,000 500,000 0 1 2 3 4 5 Year
  • 15. Nigeria – 12 project states Campaigns children under 5 10,000,000 100.0% 9,000,000 90.0% Proportion of hh with at least one net in % 8,000,000 80.0% Number of nets distributed 7,000,000 70.0% 6,000,000 60.0% total net output 5,000,000 50.0% commercial ITN coverage 4,000,000 40.0% 3,000,000 30.0% 2,000,000 20.0% 1,000,000 10.0% 0 0.0% 0 1 2 3 4 5 Year
  • 16. Nigeria – 12 project states Campaigns children under 5 + ANC 10,000,000 100.0% 9,000,000 90.0% Proportion of hh with at least one net in % 8,000,000 80.0% Number of nets distributed 7,000,000 70.0% 6,000,000 60.0% total net output 5,000,000 50.0% commercial ITN coverage 4,000,000 40.0% 3,000,000 30.0% 2,000,000 20.0% 1,000,000 10.0% 0 0.0% 0 1 2 3 4 5 Year
  • 17. Nigeria – 12 project states Campaigns children under 5 + ANC + commercial subsidy 10,000,000 100.0% 9,000,000 90.0% Proportion of hh with at least one net in % 8,000,000 80.0% Number of nets distributed 7,000,000 70.0% 6,000,000 60.0% total net output 5,000,000 50.0% commercial ITN coverage 4,000,000 40.0% 3,000,000 30.0% 2,000,000 20.0% 1,000,000 10.0% 0 0.0% 0 1 2 3 4 5 Year
  • 18. Nigeria – 12 project states Campaigns children under 5 + ANC + commercial subsidy + unsubsidized 10,000,000 100.0% 9,000,000 90.0% Proportion of hh with at least one net in % 8,000,000 80.0% Number of nets distributed 7,000,000 70.0% 6,000,000 60.0% total net output 5,000,000 50.0% commercial ITN coverage 4,000,000 40.0% 3,000,000 30.0% 2,000,000 20.0% 1,000,000 10.0% 0 0.0% 0 1 2 3 4 5 Year
  • 19. Sustaining LLIN/ITN Targets Model
  • 20. Uganda: modelling scenarios of distribution Campaign distributions to all U5 & PW every 5 years, 50% polyethylene, 50% polyester 10,000,000 100.0% 9,500,000 9,000,000 90.0% Proportion of hh with at least one net in % 8,500,000 8,000,000 80.0% 7,500,000 Number of nets distributed 7,000,000 70.0% DHS 6,500,000 2006 6,000,000 60.0% 15.9% 5,500,000 actual distribution 5,000,000 50.0% projected 4,500,000 ITN coverage 4,000,000 40.0% 3,500,000 DHS 2000/01 3,000,000 30.0% 2,500,000 1.6% 2,000,000 20.0% 1,500,000 1,000,000 10.0% 500,000 0 0.0% 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Year
  • 21. Uganda: modelling scenarios of distribution Initial campaign U5 & PW then 80% of PW-ANC, 50% polyethylene, 50% polyester 10,000,000 100.0% 9,500,000 9,000,000 90.0% Proportion of hh with at least one net in % 8,500,000 8,000,000 80.0% 7,500,000 Number of nets distributed 7,000,000 70.0% 6,500,000 6,000,000 60.0% 5,500,000 actual distribution 5,000,000 50.0% projected 4,500,000 ITN coverage 4,000,000 40.0% 3,500,000 3,000,000 30.0% 2,500,000 2,000,000 20.0% 1,500,000 1,000,000 10.0% 500,000 0 0.0% 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Year
  • 22. Uganda: modelling scenarios of distribution Initial campaign U5 & PW then 80% of PW-ANC plus 25% of households buy, 50% polyethylene, 50% polyester 10,000,000 100.0% 9,500,000 9,000,000 90.0% Proportion of hh with at least one net in % 8,500,000 8,000,000 80.0% 7,500,000 Number of nets distributed 7,000,000 70.0% 6,500,000 6,000,000 60.0% 5,500,000 actual distribution 5,000,000 50.0% projected 4,500,000 ITN coverage 4,000,000 40.0% 3,500,000 3,000,000 30.0% 2,500,000 2,000,000 20.0% 1,500,000 1,000,000 10.0% 500,000 0 0.0% 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Year
  • 24. The Evidence from Kenya Noor et al, 2007
  • 25. The Evidence from Mozambique 100 Cumulative % of households with intervention by wealth quintile Equity line 90 Concentration Curve Com LLIN Pub LLIN 80 SM LLIN 70 60 Equity of LLIN by Distribution Mechanism 50 40 Concentration Index 30 Public -0.11 20 Commercial +0.11 10 Social Marketing +0.42 0 0 10 20 30 40 50 60 70 80 90 100 Cumulative % of all households by wealth quitile
  • 26. Reaching the Poor - Prevention • Kenya evidence – Shows free campaigns are pro-poor – Shows inequity of single-branded social marketing • Mozambique evidence – Shows free ANC and campaign distributions are pro-poor – Show reasonable equity for commercial sector – Shows inequity of single-branded social marketing
  • 27. The reach of our partnership Distribution Networks Sprin l– gfield g l oba exten s/Af P atem wide sive c cott – n rk farme ot natio n netwo rs net ton tio work dis tribu cal aceuti CHAN MediPharm – Pharm ers – well Depots serving all six C.Zard – over 150 ur ma nufact networks zones retailers country-w ide red structu Har exten vestfield – Rosies Textile s– sive d etwork netwo istribu tion distribution n rk in s d Kano outh for SE, SW an
  • 28. Price Support for Sustainability
  • 29. Price Support • Price support is channelled through the commercial sector • Implementing agency does not retain the price support/subsidy • Pioneering approach: done in Uganda and Mozambique by MC • Price support aims to: – Reduce the price of quality/qualified LLINs – Increase competition and choice – Extend the market reach – Support the development of a viable and expanding market
  • 30. Price support – does it work? • Malaria Consortium experience in Mozambique and Uganda : – Increased commercial sector sales of LLINs – Increased number of brands on market – Reduced retail price of LLINs to compete with conventional untreated (and often poor quality) nets – Commercial sector sales rose at a time of mass free LLIN distributions
  • 31. MCP commercial partners’ ITN sales, Mozambique 340,000 320,000 300,000 280,000 institutional 260,000 retail Cumulative ITN sales 240,000 220,000 200,000 180,000 160,000 140,000 120,000 100,000 80,000 60,000 40,000 20,000 0 MAY MAY JAN MAR APR JAN MAR APR AUG AUG JUL OCT JUL OCT NOV SEP NOV SEP NOV DEC JUN DEC JUN DEC FEB FEB 2005 2006 2007
  • 32. Examples of commercial sector development 100.0% 5,000,000 public and civil society social marketing 90.0% commercial partners 4,500,000 estimated informal market % LLIN 80.0% 4,000,000 70.0% 3,500,000 Proportion of nets LLIN U Total number of nets 60.0% 3,000,000 g a 50.0% 2,500,000 n d 40.0% 2,000,000 a 30.0% 1,500,000 20.0% 1,000,000 10.0% 500,000 0.0% 0 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
  • 33. Rapid Scale-up Since 2005 increasing investments and since 2008 good progress in many countries Based on modelling and practical experience clear indication that only mass campaign style distributions can achieve rapid scale-up towards universal coverage
  • 34. Limitations of Campaigns However, loss of nets through “wear and tear” and other behavioural factors starts early Model Field data 100% 100% 100 90% 90% 90 80% 80% 80 Households with at least 1 ITN 70% 70% 70 60% 60% 60 50% 50% 50 40% 40% 40 Togo 30% 30% 30 Sofala - Moz 20% 20% 20 Manica - Moz 10% 10% 10 Law ra - Ghana 0% 0% 0 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 0 1 2 3 4 5 6 7 8 Years Years
  • 35. Limitations of Campaigns Even repeated campaigns can not sustain high levels of coverage in an continuous fashion 100% 100% 90% 90% 80% 80% Households with at least 1 ITN 70% 70% 60% 60% 50% 50% 40% 40% 30% 30% 20% 20% 10% 10% 0% 0% 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Years
  • 36. Need for continuous distributions Distributions are needed that supply LLIN to target groups and/or customers in a continuous manner over long periods of time To reach new families To replace torn, lost or destroyed nets To fill gaps in family demand for nets not covered by campaign distributions To satisfy demand for choice (size, shape, colour of nets)
  • 37. Channels for continuous distributions Primary distribution mechanisms are Routine health services (ANC/EPI) Commercial retail market Unsubsidized Subsidized through “total market approach” Additionally and/or in places were neither health services nor the market can reach the population alternatives must be developed Through community based approaches Schools Religious institutions
  • 38. Sustaining high coverage Modelling suggest that this mixed approach will sustain high coverage (emerging support from data) 100% 100% 90% 90% 80% 80% Households with at least 1 ITN 70% 70% ANC 85% & 20% hh 60% ANC 85% & 40% hh 60% 50% 50% 40% 40% 30% 30% 20% 20% Single campaign 10% 10% 0% 0% 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Years
  • 39. The role of commercial sector Emerging data from Uganda and Nigeria seem to support this Within 5 months of free distribution 4-9% of households procured an additional net from the commercial market 10 % of household buying commercial net after free net 8.9 ANC 9 Campaign 8 7 6 5.2 5 4.0 4 3 2 1 0 Adjumani Kano
  • 40.
  • 42. Distributing LLIN Number of LLIN distributed by MC Contribution of countries 10,000,000 8,904,048 9,000,000 8,000,000 7,000,000 Nigeria, 1,885,000, 21% 6,000,000 5,654,329 Uganda, 3,773,897, 43% 5,000,000 Southern Sudan, 399,320, 4% Sudan, 188,100, 2% 4,000,000 3,382,287 3,000,000 Mozambique, 2,657,731, 30% 2,000,000 1,000,000 657,612 10,000 47,135 144,512 0 2003 2004 2005 2006 2007 2008 2009
  • 43.
  • 44. Retention of LLIN after 6 Months 100 90 80 Proportion of nets retained 70 60 50 40 30 20 10 0 Adjumani Jinja Katakwi Kitgum Gulu Cabo Inhambane Nampula Manica Sofala Delgado Uganda Mozambique
  • 45. Equity of distribution Favouring the-poor Concentration Curve Concentration Curve 100 Uganda ANC and campaign Mozambique, ANC 100 Cumulative percentage of households with intervention 90 90 Cumulative percentage of wealth quintiles 80 among hh with person to net ratio <=2.0 80 70 70 60 60 50 50 40 40 30 30 20 20 equity line distribution 10 10 0 0 0 10 20 30 40 50 60 70 80 90 100 0 10 20 30 40 50 60 70 80 90 100 Cumulative percentage of wealth quintiles in sample Cumulative percentage of households
  • 46. Impact of LLIN Monitoring area Kamwenge, Uganda 100 90 Proportion with malaria parasites 80 Increased access to health services 70 1994 60 1997 ACT introduced 1998 50 2007 2008 40 LLIN campaign 30 20 10 0 0 1 2 3 4 5 6 Age in years
  • 47. The New Paradigm • What do we mean? – Global recognition of malaria problem – Sufficient financing available – Lofty ambitions – Move from focus on burden reduction to focus on transmission reduction • What must this translate into? – Converted into successful malaria control – Particularly higher transmission countries. • The heartland.
  • 48. Scaling up and beyond • Aggressive promotion of single solutions – GFATM funding forcing policy (examples?) – LLIN delivery through measles campaigns – Home-management of malaria (one disease system) • Toward single models for delivery • Blunt instrument • Some value: – Increase coverage quickly – Focus on a single delivery models for quick results
  • 49. Scaling up and beyond • Longer term thinking • Reflect the diversity: – Epidemiology – Socio-economic settings – Health systems • Grounded/centred where the problem is • Locus: local rather than global
  • 50. Heightened advocacy The Paradigm Shift: Global beyond burden, Increasing pressure conformity progress towards transmission 2010 coverage targets Si ng Bl l e un so t ,s lu tio ho ns r t- to te de rm in liv st er ru y m en t Range of delivery models Epidemiology Socio-economic settings Health systems Local diversity