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TOPIC 3 – LUNG FUNCTION CONTINUED 
Give definitions and values for the majority respiratory volumes and capacities at rest and during exercise 
Interpret a spirometer trace 
Explain the principles of diffusion and the importance of partial pressure in the process of gaseous exchange 
Describe the process of gaseous exchange at (a) the lungs and (b) the tissues and muscles 
Describe the effects of training on lung volumes and capacities and gaseous exchange 
Explain the importance of carbon dioxide in the control of breathing 
Learning Outcomes: 
A – Use independent skills to develop an in-depth 
understanding of the respiratory centres 
role on breathing - CS, CJ, SF, RM, CE 
B – Explain important key terms in relation to 
lung capacities and volumes – JH, AC, AA 
C – Identify the different key terms associated 
with lung capacities and volumes – JB, JB, GB 
Do Now Task – Draw 2 flow diagrams outlining the 
mechanics of breathing in the lungs
LUNG VOLUMES AND CAPACITIES 
We know we can vary the depth and volume of our breathing and no matter how 
hard you try you can never completely empty your lungs of air. 
This is a good thing because of the moisture around the alveoli would mean that 
they would stick the lungs together and cause them to collapse. 
Meaning we have a large amount of air in reserve in our lungs when we are even 
produce shallow breaths 
Looking at a reading of our lung inspirations and expirations we can then 
identify the different volumes and capacities they can hold
Tidal Volume – Amount of air breathed in or out per breath 
When we exercise what happened to the depth of our 
breathing? 
Increases 
This means the tidal volume also increases as we need to use 
what air we have in reserve to provide the body with the 
required air. 
What does this air include? 
Why do we need oxygen?
Vital Capacity – Maximum amount of air exhaled after a maximal inspiration 
This does not change whether we are breathing shallow or heavy 
Vital Capacity can be measured by a simple equation 
VC = TV+IRV+ERV 
Vital Capacity = Tidal Volume + Inspiratory Reserve Volume + Expiratory Reserve 
Volume 
Inspiratory Reserve Volume = Maximal amount of air forcibly inspired in addition to 
tidal volume 
Expiratory Reserve Volume = Maximal amount of air forcibly expired in addition to 
tidal volume
Residual Volume – Amount of air left in the 
lungs after a maximal expiration 
Why is there always a residual volume? 
Therefore our Total Lung Capacity is everything 
put together 
TLC = TV + IRV + ERV + RV
MINUTE VENTILATION 
Bringing air in and out of our lungs is known as ventilation. 
Minute ventilation = the amount of air that is moved in and out of the lungs in one minute. 
It is a product of our depth of breathing (TV) and the frequency we breath (breaths per 
minute). 
What can affect our minute ventilation? 
Rate can vary from 12-15 to up to 60 per minute 
Tidal volumes can also vary from 0.5 litres during quiet breathing to 3 litres 
VE = Frequency of breathing x Tidal Volume (ml)
Task
GAS EXCHANGE 
What’s the point in breathing? 
Oxygen in the air – lungs – cells around the body 
Air is a mixture of gases but what two are important? 
Oxygen and Carbon Dioxide 
All gases tend to evenly distribute themselves. So if there is a gas 
on one side of a semi-permeable membrane in high concentration 
and a lower amount on the other side. These gases will naturally 
move to equalise themselves. 
This process is called? 
Diffusion
DIFFUSION 
Gases can only move from high pressure to low pressure if there is 
that pressure distance. 
This is called a diffusion gradient. 
This movement evenly distributes the molecules until there is no 
pressure difference. 
No pressure – No gradient – No diffusion 
Diffusion is completely dependent on their always being a pressure 
gradient
DIFFUSION IN THE LUNGS 
The walls of the alveoli are semi-permeable therefore allowing the 
passage of oxygen and carbon dioxide molecules through it holes. 
This concentration of gas is known as partial pressure, which is 
the pressure exerted by a single gas in a mixture of gases. 
This is measured in mmHg (millimetres of mercury)
Diffusion in the 
lungs
SUMMARY 
There are a number of factors that make diffusion of oxygen from 
lungs to blood very efficient. 
 Permeability of the alveoli and capillary cell walls 
 Short distance from alveoli to capillary 
 Readiness of haemoglobin to combine with oxygen to form oxyhaemoglobin 
 Diffusion gradient caused by partial pressures 
 Large surface area of alveoli 
 Slow movement of blood through thin narrow capillaries 
 Moisture layer enhancing the uptake of oxygen
CONTROL OF BREATHING 
Respiration is controlled by the respiration centre in a part of the brain known as 
the medulla oblongata. 
This is located in the brain stem, found between the spinal cord and upper brain. 
The respiratory centre controls both the rate of breathing and depth of breathing 
using both neural and chemical control. 
http://www.youtube.com/watch?v=F0OBkR00OZE
WHEN AT REST 
There is an inspiratory and expiratory centre. 
During normal breathing the inspiratory centre sends nerve 
impulses to the diaphragm and intercostal muscles telling them to 
contract so we breath in. 
After 2 seconds the system stops allowing the above to relax so we 
breath out.
DURING EXERCISE 
Use books to write notes on how there are chemical and 
neurological changes within the body to allow for breathing to 
increase and deepen 
http://www.youtube.com/watch?v=_BFDgTci0ck
Chemical Changes
Neurological Changes
EXAM QUESTIONS 
How is ‘breathing rate’ controlled to meet the demands of changing levels of 
exercise? 
The alveoli provide the lungs with a large surface area for diffusion. 
Name two other structural features of the lungs that assist diffusion.
ANSWERS 
A. (Exercise/movement) - more carbon dioxide 
B. Increased acidity/decrease in pH/increase hydrogen ions (in blood) 
C. Detected by chemoreceptors 
D. (Nerve impulses to) respiratory centre/medulla (of brain) 
E. Phrenic nerve 
F. Diaphragm/intercostal muscles/sternocleidomastoids/scalene/pectoralis 
minor/abdominals 
A. Large blood supply; 
B. Thin/semi-permeable membrane for 
diffusion/one cell thick/walls are thin; 
C. Short distance for diffusion; 
D. Layer of moisture; 
E. Slower blood flow/transit time.

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Lesson 2. lung volumespptx

  • 1. TOPIC 3 – LUNG FUNCTION CONTINUED Give definitions and values for the majority respiratory volumes and capacities at rest and during exercise Interpret a spirometer trace Explain the principles of diffusion and the importance of partial pressure in the process of gaseous exchange Describe the process of gaseous exchange at (a) the lungs and (b) the tissues and muscles Describe the effects of training on lung volumes and capacities and gaseous exchange Explain the importance of carbon dioxide in the control of breathing Learning Outcomes: A – Use independent skills to develop an in-depth understanding of the respiratory centres role on breathing - CS, CJ, SF, RM, CE B – Explain important key terms in relation to lung capacities and volumes – JH, AC, AA C – Identify the different key terms associated with lung capacities and volumes – JB, JB, GB Do Now Task – Draw 2 flow diagrams outlining the mechanics of breathing in the lungs
  • 2. LUNG VOLUMES AND CAPACITIES We know we can vary the depth and volume of our breathing and no matter how hard you try you can never completely empty your lungs of air. This is a good thing because of the moisture around the alveoli would mean that they would stick the lungs together and cause them to collapse. Meaning we have a large amount of air in reserve in our lungs when we are even produce shallow breaths Looking at a reading of our lung inspirations and expirations we can then identify the different volumes and capacities they can hold
  • 3. Tidal Volume – Amount of air breathed in or out per breath When we exercise what happened to the depth of our breathing? Increases This means the tidal volume also increases as we need to use what air we have in reserve to provide the body with the required air. What does this air include? Why do we need oxygen?
  • 4. Vital Capacity – Maximum amount of air exhaled after a maximal inspiration This does not change whether we are breathing shallow or heavy Vital Capacity can be measured by a simple equation VC = TV+IRV+ERV Vital Capacity = Tidal Volume + Inspiratory Reserve Volume + Expiratory Reserve Volume Inspiratory Reserve Volume = Maximal amount of air forcibly inspired in addition to tidal volume Expiratory Reserve Volume = Maximal amount of air forcibly expired in addition to tidal volume
  • 5. Residual Volume – Amount of air left in the lungs after a maximal expiration Why is there always a residual volume? Therefore our Total Lung Capacity is everything put together TLC = TV + IRV + ERV + RV
  • 6. MINUTE VENTILATION Bringing air in and out of our lungs is known as ventilation. Minute ventilation = the amount of air that is moved in and out of the lungs in one minute. It is a product of our depth of breathing (TV) and the frequency we breath (breaths per minute). What can affect our minute ventilation? Rate can vary from 12-15 to up to 60 per minute Tidal volumes can also vary from 0.5 litres during quiet breathing to 3 litres VE = Frequency of breathing x Tidal Volume (ml)
  • 8. GAS EXCHANGE What’s the point in breathing? Oxygen in the air – lungs – cells around the body Air is a mixture of gases but what two are important? Oxygen and Carbon Dioxide All gases tend to evenly distribute themselves. So if there is a gas on one side of a semi-permeable membrane in high concentration and a lower amount on the other side. These gases will naturally move to equalise themselves. This process is called? Diffusion
  • 9. DIFFUSION Gases can only move from high pressure to low pressure if there is that pressure distance. This is called a diffusion gradient. This movement evenly distributes the molecules until there is no pressure difference. No pressure – No gradient – No diffusion Diffusion is completely dependent on their always being a pressure gradient
  • 10.
  • 11. DIFFUSION IN THE LUNGS The walls of the alveoli are semi-permeable therefore allowing the passage of oxygen and carbon dioxide molecules through it holes. This concentration of gas is known as partial pressure, which is the pressure exerted by a single gas in a mixture of gases. This is measured in mmHg (millimetres of mercury)
  • 13. SUMMARY There are a number of factors that make diffusion of oxygen from lungs to blood very efficient.  Permeability of the alveoli and capillary cell walls  Short distance from alveoli to capillary  Readiness of haemoglobin to combine with oxygen to form oxyhaemoglobin  Diffusion gradient caused by partial pressures  Large surface area of alveoli  Slow movement of blood through thin narrow capillaries  Moisture layer enhancing the uptake of oxygen
  • 14. CONTROL OF BREATHING Respiration is controlled by the respiration centre in a part of the brain known as the medulla oblongata. This is located in the brain stem, found between the spinal cord and upper brain. The respiratory centre controls both the rate of breathing and depth of breathing using both neural and chemical control. http://www.youtube.com/watch?v=F0OBkR00OZE
  • 15. WHEN AT REST There is an inspiratory and expiratory centre. During normal breathing the inspiratory centre sends nerve impulses to the diaphragm and intercostal muscles telling them to contract so we breath in. After 2 seconds the system stops allowing the above to relax so we breath out.
  • 16. DURING EXERCISE Use books to write notes on how there are chemical and neurological changes within the body to allow for breathing to increase and deepen http://www.youtube.com/watch?v=_BFDgTci0ck
  • 19. EXAM QUESTIONS How is ‘breathing rate’ controlled to meet the demands of changing levels of exercise? The alveoli provide the lungs with a large surface area for diffusion. Name two other structural features of the lungs that assist diffusion.
  • 20. ANSWERS A. (Exercise/movement) - more carbon dioxide B. Increased acidity/decrease in pH/increase hydrogen ions (in blood) C. Detected by chemoreceptors D. (Nerve impulses to) respiratory centre/medulla (of brain) E. Phrenic nerve F. Diaphragm/intercostal muscles/sternocleidomastoids/scalene/pectoralis minor/abdominals A. Large blood supply; B. Thin/semi-permeable membrane for diffusion/one cell thick/walls are thin; C. Short distance for diffusion; D. Layer of moisture; E. Slower blood flow/transit time.