2. Common Artifact Sources in MPI
System
Non-uniformity
Bad COR
Patient related
Upward creep (heart)
Body fat attenuation
Diaphragm attenuation
Patient motion
3. System Artifacts
Artifacts coming from the camera system are usually
avoidable by performing QC checks on a regular
basis
Non-uniformity artifacts can show up as “cold” or “hot”
spots on daily floods
COR Checks can identify a bad COR
COR artifacts will cause a break in the sinogram of the cine
SPECT acquisition and can cause artifacts after reconstruction
4. Patient Related
Upward creep of heart
Sometimes occurs during the post-stress images if the
stress test was recently completed (treadmill/exercise)
Change in respiration depth can cause the heart to move
upward gradually during acquisition
More common in:
Woman
COPD
Can result in false-positive results
Inferoseptal defect
Anteroseptal defect
Patient breathing should be monitored and sufficient time
should be waited prior to imaging
5. Patient Related
Soft Tissue
Body weight and habitus
Physician must be aware of patient factors that could
contribute to soft tissue attenuation
Muscle and fat can both cause attenuation
Artifact can be a false-positive
Observe wall-motion and thickening; if decreased then
defect is most likely real
Breast tissue artifacts
Anterior, anterolateral, and anteroseptal perfusion defects
Defect can appear reversible if the breast tissue is not in the
same place in both rest and stress images
6. Patient Related
Soft tissue (cont)
Lateral chest wall fat
Fixed lateral wall defect
Diaphragmatic attenuation
Can vary in rest and stress images due to different position of
diaphragm
Fixed inferior wall defect
Common in obese patients
Patient can be imaged prone if artifact is suspected, to move
heart away from diaphragm
7. Patient Related
Abdominal Visceral/Bowel Uptake
Artifact causes increased activity in the inferior wall of the
heart
Liver, gallbladder, bowel
Water and food can displace bowel activity
Can image patient prone
8. Patient Related
Patient motion
Location of artifact will depend on when motion occurred
during study and in what direction the motion was in
Worse if motion occurs in middle of acquisition
Make sure patient is comfortable and understands that
motion can cause a suboptimal study
Use patient immobilization straps around chest/arms to
help patient’s chest remain still
Keep patient from sleeping
Evaluate sinogram for patient motion
Motion correction software available from some vendors