Joseph Holson

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Dr. Joseph Holson has more than 35 years of experience as a scientist, business executive, and educator in the disciplines of toxicology and product development. His internationally recognized expertise in developmental and reproductive toxicology, pharmacokinetics, and risk assessment, including extensive experience with study design, data interpretation, and interspecies extrapolation of health effects data, strengthened his executive leadership of WIL Research Laboratories through two decades of continuous growth. Dr. Holson has served as principle investigator in more than 600 safety assessment studies, including during his tenure as President of WIL Research.

joseph holson developmental toxicology developmental and reproductive toxicology placentation data interpretation reproductive toxicology wil research pediatric toxicity testing regulatory toxicology juvenile toxicity testing wil research wil research wil research wil research wil research human health risk assessment prenatal toxicity fdama thyroid juvenile toxicity studies postnatal evaluation edstac toxicity screening tests

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Findings of Developmental Toxicity Studies of HBOC-201 in Rodent and Canine Models

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Probable False Positive Finding of Rodent Prenatal Toxicity for a High Molecular Weight Protein Oxygen Therapeutic

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Relative Morphology of Extraembryonic Membranes in Mammals: Their Roles in Histiotrophic Nutrition and Possible Sites of Developmental Insult

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Aspects of Postnatal Growth - Ontogeny of Organ Systems

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Features of safety assessment studies to be considered in assessing thyroid effects of reproduction and their relevance to human health

Há 10 anos • 994 Visualizações

Study Design Considerations Affecting Interpretation of Developmental Toxicity Data

Há 10 anos • 1105 Visualizações

Current Regulatory Requirements in Developmental and Reproductive Toxicity Assessments: Segmental Study Designs vs. the Biologic Continuum

Há 10 anos • 1801 Visualizações

Joseph Holson

Findings of Developmental Toxicity Studies of HBOC-201 in Rodent and Canine Models

Probable False Positive Finding of Rodent Prenatal Toxicity for a High Molecular Weight Protein Oxygen Therapeutic

Relative Morphology of Extraembryonic Membranes in Mammals: Their Roles in Histiotrophic Nutrition and Possible Sites of Developmental Insult

Aspects of Postnatal Growth - Ontogeny of Organ Systems

Features of safety assessment studies to be considered in assessing thyroid effects of reproduction and their relevance to human health

Study Design Considerations Affecting Interpretation of Developmental Toxicity Data

Current Regulatory Requirements in Developmental and Reproductive Toxicity Assessments: Segmental Study Designs vs. the Biologic Continuum

Interpretation of Low-Incidence Findings in Developmental and Reproductive Toxicity Studies

Postnatal Evaluation in Developmental and Juvenile Toxicity Studies

Screening Tests for Toxic Chemicals: An Overview

Human Clinical Relevance of Developmental and Reproductive Toxicology and Nonclinical Juvenile Testing

Reproductive Toxicology: History and State of Regulatory Science

Regulatory and Scientific Impact of FDAMA

The Pregnant, Unborn and Children as Sensitive Subpopulations Per Se