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A tactical approach to writing your
grant proposal
Karol Watson, MD, PhD
UCLA CTSI K to R Workshop
October 29, 2015
4-6 month time-line: 1st month
• Pick a topic you love and get excited to be
creative
– should be natural extension of your K work
• Draft specific aims
• Start to put together scientific team
• Map out calendar
– meet with your admin team to determine key
dates
– vacations, ward attending?
– set target dates to get drafts to Co-Is
3-4 months out:
Meet with your Program Official
• Remember that most PO’s love seeing K
awardees get R01s
– relationship evolves during your K
• Phone vs. email?
• Will he/she will read your specific aims?
• Suggestions re study section?
• Cover letter can mention your PO
• Send thank you email and copy of grant
Putting Together your Team: think both as
a reviewer and as PI
• Interdisciplinary teams increasingly attractive
• Each team member needs to be making
unique/complimentary contribution
• Consider linking with strengths of your
institution
– Will be attractive to reviewers
– Good opportunity to expand your network
Putting Your Team Together
(Continued)
• Think carefully about subcontracts (allow
extra time)
• Balance of seniority levels
• Choose people you want to work with
Don’t under-budget:
• Project Director salary
• Ground transportation for staff
• Cell phones and service
• Translations
• Data storage (consider scanning)
Writing the Grant
• Approach (Methods) is VERY important
– Begin writing early. Do not wait.
• Remember your audience
– Few MDs
– May know nothing about your area of research
– Make it easy on the reviewer
Telling your Story:
Preliminary Studies
• Purpose:
– (Findings that support your hypotheses)
– Most important: to show the reviewer your team
has experience to do the project
Keys to Success
• Innovation and Creativity is important
– Looking for new solutions to old problems
– How do you create creativity?
• Calling the Program Officer is a critical
element
– It is estimated that up to 85% of all successful
grant seekers have had contact with the
program officer
Grant Writing
• Start early
• Seek advice from colleagues
• Start with a good idea
• Talk to your NIH Program Official(s)
• Use the NIH webpage (www.nih.gov)
• Remember review criteria
• Follow instructions carefully
MOST IMPORTANT SLIDE!
Most common reasons for not receiving
funds:
• Lack of new or original ideas
• Diffuse, superficial or unfocused research plan
• Lack of knowledge of published relevant work
• Lack of experience in the essential methodology
• Uncertainty concerning the future directions
• Questionable reasoning in experimental approach
• Absence of acceptable scientific rationale
• Unrealistically large amount of work
• Lack of sufficient experimental detail
• Uncritical approach

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K-to-R Workshop: A Tactical Approach to Writing Your Proposal

  • 1. A tactical approach to writing your grant proposal Karol Watson, MD, PhD UCLA CTSI K to R Workshop October 29, 2015
  • 2. 4-6 month time-line: 1st month • Pick a topic you love and get excited to be creative – should be natural extension of your K work • Draft specific aims • Start to put together scientific team • Map out calendar – meet with your admin team to determine key dates – vacations, ward attending? – set target dates to get drafts to Co-Is
  • 3. 3-4 months out: Meet with your Program Official • Remember that most PO’s love seeing K awardees get R01s – relationship evolves during your K • Phone vs. email? • Will he/she will read your specific aims? • Suggestions re study section? • Cover letter can mention your PO • Send thank you email and copy of grant
  • 4. Putting Together your Team: think both as a reviewer and as PI • Interdisciplinary teams increasingly attractive • Each team member needs to be making unique/complimentary contribution • Consider linking with strengths of your institution – Will be attractive to reviewers – Good opportunity to expand your network
  • 5. Putting Your Team Together (Continued) • Think carefully about subcontracts (allow extra time) • Balance of seniority levels • Choose people you want to work with
  • 6. Don’t under-budget: • Project Director salary • Ground transportation for staff • Cell phones and service • Translations • Data storage (consider scanning)
  • 7. Writing the Grant • Approach (Methods) is VERY important – Begin writing early. Do not wait. • Remember your audience – Few MDs – May know nothing about your area of research – Make it easy on the reviewer
  • 8. Telling your Story: Preliminary Studies • Purpose: – (Findings that support your hypotheses) – Most important: to show the reviewer your team has experience to do the project
  • 9. Keys to Success • Innovation and Creativity is important – Looking for new solutions to old problems – How do you create creativity? • Calling the Program Officer is a critical element – It is estimated that up to 85% of all successful grant seekers have had contact with the program officer
  • 10. Grant Writing • Start early • Seek advice from colleagues • Start with a good idea • Talk to your NIH Program Official(s) • Use the NIH webpage (www.nih.gov) • Remember review criteria • Follow instructions carefully
  • 11. MOST IMPORTANT SLIDE! Most common reasons for not receiving funds: • Lack of new or original ideas • Diffuse, superficial or unfocused research plan • Lack of knowledge of published relevant work • Lack of experience in the essential methodology • Uncertainty concerning the future directions • Questionable reasoning in experimental approach • Absence of acceptable scientific rationale • Unrealistically large amount of work • Lack of sufficient experimental detail • Uncritical approach