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1. ISAD 2012
th th
18 – 20 April 2012, Royal College of Physicians, London, UK
Day 1: Wednesday, 18th April 2012
07:30 Registration opens in lobby of RCP
08:30 – SYMPOSIUM 1 SYMPOSIUM 2 SYMPOSIUM 3
10:30 Council Chamber Linacre and Sloane Room Wolfson Theatre
Hearts and Minds: the links Bipolar Disorder and Brain Stimulation Methods for
between co morbid Substance Use Disorder Treating Depression – Critical
depression and heart Comorbidity: New Findings Review of Latest Clinical
disease and best treatment Findings and New
Session Chair: Roger Weiss Technological Advances
Session Chair: André Tylee (Harvard Medical School)
(King’s College London) Session Chair: Mark George
(Medical University of South
Carolina)
[S1.1] [S2.1] [S3.1]
08:30 Early findings from the Integrated Group Therapy for What's the latest with the
UPBEAT Cohort Bipolar Disorder and oldest? ECT advances.
André Tylee (King’s College Substance Abuse Harold Sackeim (Columbia
London) Roger Weiss (Harvard Medical University)
School)
[S1.2] [S2.2] [S3.2]
09:00 Treatment of depression in Sleep difficulties in Bipolar New advances with
heart disease Disorder and SUD transcranial magnetic
Chris Dickens Margaret Griffin (Harvard Medical stimulation
(Peninsula College of Medicine School) Klaus Ebmeier (University of
and Dentistry) Oxford)
[S1.3] [S2.3] [S3.3]
09:30 Determinants of Optimizing pharmacotherapy: Vagus Nerve Stimulation
depression in cardiac Bipolar and Alcoholism Michael Trimble (Queen’s Square
patients Ihsan Salloum (University of
Andrew Steptoe (University Miami)
College London)
[S1.4] [S2.4] [S3.4]
10:00 Final analyses of the 2-Year Tx Outcome: Bipolar v. Deep Brain Stimulation
MIND-IT study Depressed Alcoholics Thomas Schlaepfer (John Hopkins
Peter de Jonge Conor Farren (St. Patrick’s Hospital)
(UMCG University of University)
Groningen)
10:30 –
11:00 Tea/Coffee Break, Exhibition and Poster Viewing
11:00 – Plenary Session 1 – Wolfson Theatre
12:00 Chair: Bernard Lerer (Hadassah-Hebrew University Medical Center)
Affective disorders – new economic realities
Martin Knapp (King's College London, Institute of Psychiatry)
12:00 – Lunch Break, Exhibition and Poster Viewing
13:30
1

2. 12:15 – Lundbeck Lunchtime Satellite Symposium
13:25 “Recent Advances in the Management of Bipolar Disorder”
Welcome and Introduction
Allan Young, Professor of Psychiatry, Imperial College London, UK
Pharmacological Basis for the Clinical Effects of Antipsychotics
Andrea Fagiolini, Associate Professor of Psychiatry, University of Siena, Italy
Asenapine in the Treatment of Bipolar Disorder I, Acute and Sustained Effects
Heinz Grunze, Professor of Clinical Psychiatry, Newcastle University, UK
Summary & Closing Remarks
Allan Young, Professor of Psychiatry, Imperial College London, UK
13:30 – SYMPOSIUM 4 SYMPOSIUM 5 SYMPOSIUM 6
15:30 Council Chamber Wolfson Theatre Linacre and Sloane Room
Mood Disorders and Diet and Nutrition: New Psychopharmacology of
Somatic Comorbidity: From Opportunities for the Affective Disorders: Is There a
Associations to Prevention and Treatment of Future?
Mechanisms Moody and Anxiety Disorders
Session Chair: Bernard Lerer
Session Chair: Martin Preisig Session Chair: Felice Jacka (Hadassah-Hebrew University
(University of Lausanne) (Deakin University) Medical Center)
[S4.1] [S5.1] [S6.1]
13:30 Mortality of 406 patients Diet and Nutrition: New Generic SSRIs: The End of
with mood disorders over opportunities for the History?
prevention and treatment of
50 years after admission Phil Cowen (University of Oxford)
mood and anxiety disorders
Jules Angst (University of
across the lifecourse
Zurich) Felice Jacka (Deakin University)
[S4.2] [S5.2] [S6.2]
14:00 Mood disorders, Mediterranean Diet, trans fatty Hormonal Therapies and
cardiovascular risk factors acids and depression. The SUN Antidepressant Development
and inflammatory markers: Project Bernard Lerer (Hadassah-Hebrew
results of a population- Almudena Sánchez-Villegas University Medical Center)
based survery (University of Las Palmas de Gran
Jennifer Glaus (University Canaria)
Hospital Center and University
of Lausanne)
[S4.3] [S5.3] [S6.3]
14:30 Bone quality in mood Dietary patterns and Pharmacogenetics and
disorders depression in Japan Antidepressant Treatment
Lana Williams (Deakin Akiko Nanri (International Clinical Julio Licinio (Australian National
University) Research Center) University)
[S4.4] [S5.4] [S6.4]
15:00 Depression and Obesity Nutritional supplements for Neural plasticity & Novel Mood
Julie Pasco (University of the treatment of mood Disorder Therapies
Melbourne) disorders Husseini Manji (Johnson &
Jerome Sarris (University of Johnson Pharmaceuticals)
Melbourne)
15:30 –
16:00 Tea/Coffee Break, Exhibition and Poster Viewing
2

3. ORAL PRESENTATION ORAL PRESENTATION ORAL PRESENTATION
16:00 – SESSION 1 SESSION 2 SESSION 3
17:30 Linacre and Sloane Room Wolfson Theatre Council Chamber
Session Chair: Elliott Session Chair: Ray Lam Session 3: Anthony Cleare
Richelson (The Mayo Clinic) (University of British Columbia) (Institute of Psychiatry, UK)
[O1.1] [O2.1] [O3.1]
Neurophysiological Physical exercise as an Suicide increased in untreated
predictors of non-response adjuvant therapy for young individuals in Sweden
16:00
to rTMS in Depression depression after "Black BOX" warnings for
Martijn Arns (Brainclinics) Jorge Mota-Pereira "suicidality" as an adverse
effect of antidepressants
Göran Isacsson
[O1.2] [O2.2] [O3.2]
The Relationship Between Aggregation of mood spectrum Computerised CBT for older
Brain Oscillatory Activity disorders in clinical and adults with depression and
and Therapeutic population based families comorbid cardiovascular
16:15
Effectiveness of Caroline Vandeleur disease -a randomised,
Transcranial Magnetic double-blind, placebo
Stimulation in the controlled trial
Treatment of MDD Nick Glozier (Sydney Medical
Andrew Leuchter (UCL) School)
[O1.3] [O2.3] [O3.3]
Relapse rates following a Co-occurring psychopathology Epilepsy and major
successful course of in parents with recurrent depression, bipolar disorder,
electroconvulsive therapy depression and risk to and suicide attempt: Evidence
16:30
for depression: A adolescent offspring for a bidirectional relationship
systematic review and Ruth Sellers (Cardiff University) Dale Hesdorffer (Columbia
meta-analysis University)
Ana Jelovac (Trinity College
Dublin)
[O1.4] [O2.4] [O3.4]
Harsh parenting and neural The Association Between Fruit Impact of co-morbid anxiety
fear circuitry function in and Vegetable Consumption and/or substance use disorder
16:45
high and low anxious and Mental Health Disorders in on outcomes of Psychotherapy
youths: Preliminary Canadians for bipolar disorder
findings Ian Colman(University of Ottawa) Maree Inder
Françoise Maheu (University
of Montréal)
[O1.5] [O2.5] [O3.5]
Change in amygdala and Lessons learned from two Depression and smoking: a
hippocampal volumes after Cochrane Reviews on five-year prospective study of
twelve weeks of paroxetine depression treatments in patients with major depressive
17:00
treatment for major patients with diabetes and disorder
depressive disorder patients with coronary artery Isometsä Erkki (University of
Henricus G Ruhe (University of disease Helsinki)
Amsterdam) Harald Baumeister
[O1.6] [O2.6] [O3.6]
Modifiable lifestyle factors, Randomized clinical trials Protective factors against
depression and underestimate the efficacy of depression during the
17:15
inflammation in the Hunter antidepressants in less severe transition from adolescence to
Community Study depression adulthood: Findings from a
Sarah Hiles Göran Isacsson national Canadian cohort
Ian Colman(University of Ottawa)
3

4. 17:30 – Poster Session
19:00
19:00 – Welcome Reception
20:30
Day 2: Thursday, 19th April 2012
08:30 – SYMPOSIUM 7 SYMPOISUM 8 SYMPOSIUM 9
10:30 Council Chamber Linacre and Sloane Room Wolfson Theatre
Are Specialised Affective Metabolic Depression: A Constitutional Determinants of
Disorder Services Useful? Specific Depression Subtype? Anxiety Disorders:
Physiological and
Session Chair: Chantal Henry Session Chair: Brenda Penninx Neuroimaging Characteristics
(University of Paris) (VU University Medical Cente)
Session Chair: Hugo Critchley
(Brighton and Sussex Medical
School)
[S7.1] [S8.1] [S9.1]
08:30 Canadian Programmes Inflammation, leptin and onset Exaggerated autonomic
Sagar Parikh (University of of depression responses and vulnerability to
Toronto) anxiety
Yuri Milaneschi (National Institutes
of Health) Satoshi Umeda (Keio University)
[S7.2] [S8.2] [S9.2]
09:00 German Algorithm Inflammation, metabolic Early emotional processing
Mazda Adli (Charite- syndrome, depression course and bodily arousal
universitatsmedizin Berlin) Nicole Vogelzangs (VU University) Henrique Sequeira (Lille
University)
[S7.3] [S8.3] [S9.3]
09:30 French network of bipolar Evidence for differential Interoceptive awareness and
expert centres underlying pathophysiology in anxiety
Bruno Etain (INSERM, U 955) melancholic versus atypical (Olga Pollatos)
depression subtypes Universität Potsdam
Femke Lamers (National Institutes Humanwissenschaftliche Fakultät
of Health)
[S7.4] [S8.4] [S9.4]
10:00 ENBREC: European Inflammation and depression Neurobiological pathways
Network of Bipolar Expert symptom profile linking socioeconomic position
Centres Martin Preisig (University of and health
Chantal Henry (University of Lausanne) Peter Gianaros (University of
Paris) Pittsburgh)
10:30 –
11:00 Tea/Coffee Break, Exhibition and Poster Viewing
Plenary Session 2 – Wolfson Theatre
Chair: Jan Scott (Newcastle University)
11:00 – Cognitive Behaviour Therapy in the Treatment and Prevention of Depression
12:00 Steve Hollon (Vanderbilt University, Nashville, USA)
12:00 –
13:30 Lunch Break, Exhibition and Poster Viewing
4

5. 13:30 – ORAL PRESENTATION ORAL PRESENTATION ORAL PRESENTATION
15:30 SESSION 4 SESSION 5 SESSION 6
Council Chamber Linacre and Sloane Room Wolfson Theatre
Session Chair: Roger Pinder Session Chair: Allan Young
(ISAD Immediate Past (Imperial College London)
President)
[O4.1] [O5.1] [O6.1]
The role of meaning in life Timing of First Exposure to Gender differences in response
13:30 in promoting resiliency to Maternal Depression and to terrorist attacks: from
late-life suicide ideation Adolescent Emotional Disorder initial response to treatment
Marnin J. Heisel (Victoria
in a National Canadian Cohort response
Hospital)
Ian Colman (University of Ottawa) Sara Freedman (Bar Ilan Univ)
[O4.2] [O5.2] [O6.2]
Age of onset and the Prevention of depression in at- Circadian rhythms in
13:45 prospectively observed risk adolescents menopausal depression
course of illness in bipolar Judy Garber (Vanderbilt Barbara Parry (University of
disorder University) California, San Diego)
William Coryell
[O4.3] [O5.3] [O6.3]
Interaction between Predictors of children's Lifetime comorbidity of major
MTHFR C677T posttraumatic stress and depression and anxiety
14:00 Polymorphism and depression after a natural disorders among a community-
traumatic childhood events
disaster: Gene by environment based sample of women:
predicts recurrence in
recurrent MDD: a 5,5-year interactions clinical correlates and
prospective study Annette La Greca (University of psychosocial features
Anja Lok (University of Miami) Jill M. Cyranowski (University of
Amsterdam) Pittsburgh Medical Center)
[O4.4] [O5.4] [O6.4]
P2RX7: Expression Stress and depression in a Trajectories of maternal
Responds to Sleep population sample of symptoms of anxiety and
14:15 Deprivation and Associates adolescents (TRAILS): the depression over 13 years:
with Rapid Cycling in
risks and benefits of exposure The influence of stress, social
Bipolar Disorder Type 1
to childhood adversities support, and maternal
Lena Backlund
Albertine Oldehinkel temperament
Anni Skipstein (Norwegian
Institute of Public Health)
[O4.5] [O5.5] [O6.5]
Longitudinal hypothalamic- Psychotic symptoms index The BraveHeart project:
pituitary-adrenal axis trait ultra-high risk for suicidal randomised controlled trial of
14:30 and state effects in behaviour in young people group cognitive behaviour
recurrent depression
with affective disorders therapy versus brief
Roel JT Mocking (University of
Amsterdam) Ian Kelleher intervention for depression in
cardiac patients
Amanda Baker (University of
Newcastle, Australia)
[O4.6] [O5.6] [O6.6]
Suicide and brain chemical Depressive problems and Preventive cognitive therapy
14:45 changes with altitude academic performance, social in recurrent depression: a 10
Perry F. Renshaw well-being, and social year follow-up of the DELTA
problems in adolescence: study
Longitudinal and bidirectional Aart H. Schene (University of
effects Amsterdam)
Charlotte Verboom
5

6. [O4.7] [O5.7] [O6.7]
15:00 Investigation of reward as Childhood stress-reactivity and A Randomized Controlled Trial
a neural biomarker for Inflammatory Mechanisms in of Psychoeducation or
depression Major Depressive Disorder Cognitive-Behavioural Therapy
Ciara McCabe (Oxford
Sarah Cohen-Woods (King’s in Bipolar Disorder: A CANMAT
University)
College London) Study
Sagar Parikh (University of
Toronto)
[O4.8] [O5.8] [O6.8]
Genetic polymorphisms, Identifying clinical risk What makes people persist
15:15 hopelessness and suicidal markers for depression in high with internet interventions for
risk in a sample of subjects risk offspring depression?
with chronic migraine and
Becky Mars (Cardiff University) Liesje Donkin
affective temperamental
dysregulation
Gianluca Serafini
15:30 –
16:00 Tea/Coffee Break, Exhibition and Poster Viewing
16:00 –
17:30 Poster Session ISAD AGM
19:30 Gala Dinner (Ironmonger’s Hall, City of London)
6

7. Day 3: Friday, 20th April 2012
Plenary Session 3 – Wolfson Theatre
08:30 – Chair: Sidney Kennedy (ISAD President)
09:30 Epigenetic basis for the transgenerational transmission of individual differences in
vulnerability for psychopathology
Professor Michael Meaney (McGill University, Montreal, Quebec, Canada)
09:30 – SYMPOSIUM 10 SYMPOSIUM 11 SYMPOSIUM 12
12:00 Linacre and Sloane Room Wolfson Theatre Council Chamber
International Society for Can we Identify those at Risk The Early Identification of Risk
Bipolar Disorders: Task of Unipolar and Bipolar for Affective Illness: Findings
Force Updates Disorders? from the Orygen Adolescent
Development Study
Session Chair: Sophia Session Chair: Jan Scott
Frangou (King’s College (Newcastle University) Session Chair: Nicholas Allen
London) (The University of Melbourne)
[S10.1] [S11.1] [S12.1]
Women's Task Force: Case finding strategies to Brain development and
Physical and Endocrine augment the early adolescent onset depression
09:30
Health in Women with identification of bipolar Sarah Whittle (The University of
Bipolar Disorder disorders Melbourne)
Aysergul Ozerdem (Dokuz Jan Scott (Newcastle University)
Eylul University Medical
School)
[S10.2] [S11.2] [S12.2]
Clinical Trials Task Force: Is there any biomarker for Family processes as predictors
10:00 Challenges & new bipolarity? of teen depression
directions in clinical trials Marion Leboyer (University of Orli Schwartz (The University of
design for Bipolar Disorder Paris) Melbourne)
Lakshmi Yatham (The
University of British Columbia)
10:30 – Tea/Coffee Break, Exhibition and Poster Viewing
11:00
[S10.3] [S11.3] [S12.3]
Neuroimaging Task Force: Neuroendocrine and other Depressive symptoms and
11:00 Neural Correlates of predictors of depression C-reactive protein in
Bipolar Disorder: What Ian Hickie (University of Sydney) adolescents: Effects of sex
have we learned so far? Michelle Byrne (The University of
Melbourne)
Sophia Frangou (King’s
College London)
[S10.4] [S11.4] [S12.4]
Biomarkers for patients Lifestyle as a risk factor for Affective Psychophysiology
11:30 with Bipolar Disorder: depression; A neglected and integration.
ISBD Taskforce Perspective opportunity for prevention? Nicholas Allen (The University of
Trevor Young (University of Michael Berk (Universities of Melbourne)
Toronto) Melbourne & Deakin)
12:00 Close of Meeting
Please note that speakers and presentation titles are subject to change at short notice
7