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4.  OPG
 Serum Alkaline Phosphatase Level
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5. Orthopantomograph
GROUND GLASS APPEARANCE
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6.  Fibrous Dysplasia
 Pagets Disease
 Osteoma
 Central ossifying fibroma
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7. Gross Specimen
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8. HISTOPATHOLOGY
SCANNERVIEW
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9. SCANNERVIEW
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11.  Clinicopathological correlation suggestive
of FIBROUS DYSPLASIA.
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12.  Goldner stain
 Sirius red
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13. GOLDNER STAIN
SCANNER VIEW
Normal boneOssifying fibroma
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14. LOW POWER
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15. FIBROUS DYSPLASIA OSSIFYING FIBROMA
NORMAL BONEwww.indiandentalacademy.com

16. Fibrous Dysplasia
Genetically based developmental anomoly
of bone forming mesenchyme with the defect
in osteoblastic differntiation and maturation
leads to replacement of normal bony tissue
by fibrous tissue and immature woven bone.
It is less cellular .
Osteoblastic riming is not seen.
Absence of capsule .
Giant cells could be seen.
Serum alkaline phosphatase activity sligtly
raised.
Ossifying Fibroma
It is a true benign neoplasm.
It is highly cellular.
Osteoblastic riming is seen.
Presence of capsule
Giant cells are not seen.
Serum alkaline phosphatase activity
normal.
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17. Ground glass appearance is seen .
 Bony trabaculae are seen to be
separated from connective tissue
stroma .
Under polarised microscope coarse
and haphazard arrangement of collagen
fibres is seen.
The abundance of osteocalcin in
fibrous dysplasia suggests that the
calcified material in fibrous dysplasia is
more similar to normal bone than that
in ossifying fibroma.
It is a mixed lesion with diffused
scattered calcification.
No such separation is seen.
Under polarised microscope fine and
regular arrangement of collagen fibres
is seen.
 Osteocalcin deficiency is seen in
ossifying fibroma .
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18. THANK YOU
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