3. Positioned for Future Growth
Targeting
Sustainable
Generic and
Specialized
Brand Markets
Established
Core
Competencies
Strong and
Flexible
Financial Profile
3
Generic pipeline targeting $26B U.S. sales
Brand pipeline focused on Central Nervous System (CNS)
Solid platform on which to build long-term growth
Track record of complex formulation and development
Established drug delivery capabilities
Hatch-Waxman expertise and Paragraph IV successes
Diversifying Generic business product mix
Building a Branded business pipeline
Financial resources and flexibility to support growth
Note: All brand/generic product sales data included herein are derived from data published by IMS for the 12 months ended September 2013.
4. Two Platforms for Growth
Generic Platform
Unique targeted ANDAs
Branded Platform
Creating highly valued CNS products
• Solid Oral Dosage (SOD)
RYTARYTM – NDA pending approval
• Alternative Dosage Form (ADF)
Commercializing Zomig® in the U.S.
First-to-File/First-to-Market emphasis
Partnerships/M&A areas
Focusing on sustainable products
• Neurology
Partnerships/M&A primarily on ADFs
• Psychiatry
69 products pending at FDA or
under development
4
Note: Data as of October 2013.
Building a product pipeline
Developing strong IP positions
5. Strategy to Create Long Term Growth
Revenue Growth
Opportunities
Operational
Improvements
Diversifying Generic
Business product mix
Focusing on improving
quality and compliance
Focusing on building a
Brand pipeline
Right-sizing manufacturing
costs and capacity
Executing business
development and M&A
activities
Enhancing management
team across the company
Supported by financial resources and strong balance sheet:
approximately $437MM cash/cash equivalents and no debt
5
Note: Data as of September 30, 2013,.
6. Committed to Improving Our Operations
• Quality first culture
• Management and organization structure changes
• Initiated an internal Quality Improvement Program (QIP)
• Working aggressively to complete key aspects of the QIP
• Third-party experts continue to assist us with:
– Review of our manufacturing and quality systems
– Enhancing our systems and standards
• Committed to resolving all observations and exceeding
current Good Manufacturing Practice
6
7. Strategic Initiatives for Generic Growth
Focusing on…
Organic Growth
through SOD and
ADF Forms
Organic Growth
Partnership
Both Solid Oral &
Mainly in ADF
Alternative Dosage
Forms (ADF)
7
Strategic Partnerships
Primarily
in ADFs
Strategic M & A
M&A
MainlyPrimarily
in ADF
in ADFs
8. 2013 Generic Product Launches
January
Oxymorphone Hydrochloride ER tablets
5, 7.5, 10, 15, 20, 30 and 40 mg
May
Authorized generic Zomig® tablets
Authorized generic Zomig® Orally Disintegrating Tablets
2.5 and 5 mg
July
Authorized generic Trilipix® Delayed Release Capsules
45 and 135 mg
Shortly…
Solaraze® Gel 3%
8
9. Diversifying Currently Marketed Portfolio
47 Currently Marketed Products
Alternative
Dosage Form
19%
13
9
25
Other Solid Oral
53%
9
Note: Data as of October 2013.
Controlled-Release
Solid Oral
28%
10. Diversifying Generic Product Pipeline
69 Future Opportunities Pending at FDA or Under Development
$26B Current U.S. Brand/Generic Sales
42
4
27
22
15
16
Pending at FDA
19 Total ADF
28% of Pipeline
10
10
2
Under Development
32 Total C-R SO
46% of Pipeline
18 Total Other SO
26% of Pipeline
Note: Date as of October 2013. All product sales data included herein are derived from data published by IMS for the 12 months ended September 2013.
11. Strategic Initiatives for Brand Growth
Focusing on…
Organic Growth
through SOD and
ADF Forms
Organic Growth
Partnership
Mainly in
Primarily in ADF
Neurology Area
11
Partnerships
Neurology &
Psychiatry Areas
M&A
M&A
Neurology
Mainly in ADF &
Psychiatry Areas
(Products/Companies)
12. Building a Brand Product Pipeline
PROJECT
PHASE I OR POC
PHASE II
IPX232
IPX…
APPROVED
Parkinson’s Disease (carbidopa-levodopa)
RYTARYTM (a)
IPX231
REGISTRATION
Migraine
Zomig®
IPX203
PHASE III
Parkinson’s Disease
Parkinson’s Disease
Migraine
Exploratory Projects
(a) On Jan. 21, 2013, the Company announced the receipt of a complete response letter from the FDA indicating that the FDA required a
satisfactory re-inspection of the Company’s Hayward manufacturing facility before the RYTARY NDA may be approved. On March 4, 2013, the
Company announced the receipt of a Form 483 following an inspection of Hayward that may hold up approval of RYTARYTM, as analytical method
validation and a portion of the stability data were generated at the Hayward facility.
12
13. RYTARYTM (IPX066):
Carbidopa and Levodopa Extended-Release Capsule
PATENT
INFORMATION
DEC.
2011
FEB.
2012
JAN. 21,
2013(a)
THROUGHOUT
2013
RYTARY™ (IPX066) for the Symptomatic Treatment of Parkinson’s Disease
1st Patent Granted
Aug. 2006
Expires May 2022
2nd Patent Granted
Dec. 2008
Expires Dec. 2028
PDUFA Date
FDA
- Received
NDA Acceptance
Complete
of NDA
Filed
Response
Filing
Letter
Pre-launch planning
More than one million people in the U.S., with 50,000-60,000
new cases diagnosed each year in the U.S. alone
13
(a) On Jan. 21, 2013, the Company announced the receipt of a complete response letter from the FDA indicating that the FDA required a
satisfactory re-inspection of the Company’s Hayward manufacturing facility before the RYTARYTM NDA may be approved. On March 4,
2013, the Company announced the receipt of a Form 483 following an inspection of Hayward that may hold up approval of RYTARYTM,
as analytical method validation and a portion of the stability data were generated at the Hayward facility.
Source: National Parkinson’s Foundation. Parkinson’s Disease Overview
14. Continuing Our Commercial Success
Building relationships with neurologists since July 2006
Licensed exclusive U.S. commercialization rights to Zomig®
Began commercializing Zomig® in April 2012
o Tablet and ZMT patents expired May 2013
Continuing commercialization of Zomig® Nasal Spray
o Nasal Spray patent expires May 2021
Since Impax Promotion
April ’12 to Sept. ‘13
Nasal Triptan Market Share, National
80%
Sumatriptan
-5% decrease
70%
60%
50%
Zomig®
+17% increase
40%
30%
Imitrex®
-7% decrease
20%
10%
14
Source: IMS NPA Weekly
Sep-13
Aug-13
Jul-13
Jun-13
May-13
Apr-13
Mar-13
Feb-13
Jan-13
Dec-12
Nov-12
Oct-12
Sep-12
Aug-12
Jul-12
Jun-12
May-12
Apr-12
Mar-12
Feb-12
Jan-12
Dec-11
Nov-11
Oct-11
0%
15. Positioned for Future Growth
Targeting
Sustainable
Generic and
Specialized
Brand Markets
Established
Core
Competencies
Strong and
Flexible
Financial Profile
Generic pipeline targeting $26B U.S. sales
Brand pipeline focused on Central Nervous System (CNS)
Solid platform on which to build long-term growth
Track record of complex formulation and development
Established drug delivery capabilities
Hatch-Waxman expertise and Paragraph IV successes
Diversifying Generic business product mix
Building a Branded business pipeline
Financial resources and flexibility to support growth
15 Note: All brand/generic product sales data included herein are derived from data published by IMS for the 12 months ended September 2013.