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Democratizing
Healthcare
Patient-
Centered
Healthcar
e
HOSPITA
L
HOME
Personalized
What’s the best
care for my needs?
Predictive
What health trends
that are likely to
develop?
Proactive
Who’s at risk? Who
needs to be
informed?
Preventative
What actions can I
take now to prevent
disease?
Proactive Personalized Health: Move to LEFT
Health Status
80% of Cost from 20% of Population
Personalized Medical Home
Smart
Sensing
Intelligent
Information
Management
Effective
Interfaces
Putting the patient at the center of their health system
Family & Friends
Healthcare
Providers
Web
Repositories
Healthcare
Institutions
Researchers
Smart
Devices
Connected
Systems
End-to-End
Analytics
Patient-Centric Home Health
Smart Big
Data
Actionable
Insights
Smart
Devices
Connected
Systems
End-to-End
Analytics
Smart Sensors for Every Sense
Smart Devices
• Non-invasive wearable sensors
• Personal biosensors
• Environmental sensors
• New data streams + machine
learning = “New vital signs”
Smart DevicesSmart Devices
Smart DevicesSmart Devices
Smart Devices
Smart Devices
Consumer
Technologies
Social Media
Technologies
Internet
Technologies
Visualisation
Technologies
Learning
Technologies
Enabling
Technologies
From glasses
to wearables
VLE
PLE
Collective
intelligence
Collaborative
environments
Next gen
batteries
Wireless
power
Tablet
Quantified
self
3D printing
Information
Visualisation
Drivers of
Disruption in
Healthcare
Smart Phone
3D Printing
Machine Learning Tags Abnormalities
Human-Centered Design
Adoption
+
Adherence
Human Nature Admires Complexity but Rewards Simplicity.
Effective Interfaces
• Multimodal
– GUI, touch, gesture, speech, …
• Mobile
– Portable, networked, wearable
• Intuitive
– Easy to learn, use, maintain
• Adaptive
• Proactive
Machine Learning Tags Abnormalities
Security
Privacy
Compliance
Machine Learning Tags Abnormalities
> 400 Million Units
by 2020
Machine Learning Tags Abnormalities
Patient Generated
Data  Big Data
Intelligent Information Management
• Longitudinal data
– Personal baseline
– Detect trends & deviations from norm
• Personal health records
– Privacy
– Sharing
– Anonymous aggregation
• Patient-centered decision support
Data Aggregation and Analytics
Artificial Intelligence for
Predictive Healthcare
From Data to Decisions
REACTIVE  PROACTIVE
SPORADIC 
CONTINOUS
Machine Learning Tags Abnormalities
EARLY ENAGEMENT
=
SUCCESS in
Healthcare
28
Regular
Accessible
Breast
Health
Monitoring
1 in 8 women
WILL BE DIAGNOSED WITH BREAST
CANCER
Machine Learning Tags Abnormalities
EARLY DETECTION
=
99% SURVIVAL
1 in 3
BREAST CANCERS IS
MISSED
47% of women have dense breasts
BUT Mammogram misses tumors in
dense breasts
Breast Cancer screening
is sporadic, inaccessible, and expensive
High risk women need more regular
screening
Current Breast Ultrasound
Sources: American Cancer Society, American College of Radiology
Image Quality is
Operator Dependent
False Positive
Cost ~ 5-10K
SonoSite PhilipsGE VSCAN
GE Siemens
Cost ~ $200-400K
35.7% More Cancer Detected with
Automated Breast Ultrasound *
Point-of-Care
Automated
3D
ULTRASOUNDWEARABLE MOBILE APP
Automated + Low-Cost
2
Patents
Machine Learning Tags Abnormalities
Machine Learning Detect Changes EARLY
and Track Over Time
2 Minutes Scan
 No Radiation
 Actionable Feedback
Clinical Study with 100 Women
iSono
GE
Early Adopters
Market of $4B
CAGR of 10.8% Pricing:
$300/Device
$20/User/M
onth ARR
US Market
8.6M
Women at
Very High
Risk
Total
Addressable
Market of $32B
102M
Women over
30 in US
Early Stage
Diagnosis
$20K pp
Late Stage
Diagnosis
$100-300K pp
$18.5B Direct Cost of Breast Cancer
+
$14B Lost Productivity Per Year
for self-insured employers and health
insurance companies
Why Would Payers Care?
44
Regular and Accessible Breast
Health Monitoring
$32B Market
Personalized, Proactive
Healthcare
Better
Health
Better Care
Better Value
maryam@isonohealth.com
Making Sense of Big Data
• Understanding human behavior from sensor data
– Integrating vastly different kinds of data
– Incorporating commonsense knowledge
– Compute intensive methods for learning & inference
• Embedded, mobile, and distributed systems
– Data transport in dynamic, heterogeneous environments
– Security and data sharing
– Data / annotation / interpretation streams
49
System Concept
Personal Health Monitoring
• Preventative Healthcare
• Chronic Care Management
• Post-surgery Monitoring
• Borrow from the field of machine
health monitoring
– Identify the most minimally invasive ways to capture data
– Mine collected data to identify personal baselines, data
defined models and track changes
– Identify patient preferences and create a system that gives
a valuable user experience
– Identify effective ways to share data with health care
providers
Measure
• Cardiac function (ECG)
• Respiration (Sound/ECG)
• Activity (Accelerometry) Alivetec ECG & motionTouch screen
mobile phone
Personal Health Management Assistant
• Provide effective, intuitive access to
information in Personal Health Record
• True conversational interaction
– UR Computer Science leading center of research
on dialog systems
– Not just canned responses: reasons about user
model and dialog context
• Target population: Heart failure patients
following self-care guidelines
– Collect information relevant to condition
– Interpret with respect to self-care guidelines
– Suggest appropriate course of action
– Facilitate information sharing with doctors &
family
Smart Sensors
Go-to-Market Strategy
High Risk
Women
Surveillance
Women over
30
Screening
Channels
&
Partners
• Women Healthcare
Centers
• BC Advocacy
Groups
• Genetic
Testing/Counseling
• Corporate Wellness
• Mail-in-Subscription
• Walk-in Health Clinics
Breast Cancer
Patient
Monitoring
• Breast Cancer
Centers
• BC Pharma
1Billion Women
need additional
screening
50M Women at
Very High Risk
due to Family
History or
Genetics
Every Year 1.7M New Cases of Breast Cancer
Market
Over 500,000 Breast Cancer Deaths/year
Competitive Landscape
Portable Ultrasound Automated Ultrasound
35% More Cancers Detected
Cost: $200K +
Wearable Sensor Solutions
Cost: $5-10K
Disadvantage: Probe Operator Error
1Billion Women
over 30 in the
World with
Dense Breasts
50M Women at
Very High Risk
due to Family
History or
Genetics
Every Year 1.7M New Cases of Breast Cancer
Market
Over 500,000 Breast Cancer Deaths/year
Early Adopters
Market of $4B
CAGR of 10.8% Pricing:
$300/Device
$20/User/M
onth ARR
US Market
8.6M
Women at
Very High
Risk
Total
Addressable
Market of $32B
102M
Women over
30 in US
European Market
Every Year 500,000 New Cases of Breast Cancer
Over 140,000 Breast Cancer Deaths/year
14M Women at
Very High Risk due
to Family History or
Genetics
Early Adopters
Market of $8B
Women with Dense
Breasts
Sporadic and Inaccessible
Screening
High Risk Women
Current Breast Cancer Screening
Self Breast Exam
Ineffective for small
tumors
Mammogram
Low Sensitivity
X-ray Radiation
1Billion Women
over 30 in the
World with
Dense Breasts
50M Women at
Very High Risk
due to Family
History or
Genetics
Every Year 1.7M New Cases of Breast Cancer
Global Market
Over 500,000 Breast Cancer Deaths/year
Quantitative Ultrasound + Machine Learning
• A multi-parameter longitudinal approach improves
precision
Grayscale Image
Qualitative
features
• Shape
• Contour
• Shadow
Raw RF signal
Quantitative features
• Power spectrum
• Statistics
• Frequency
dependence
Parametric Change
Longitudinal features
• Volume density
• Cell death/growth
• Tissue acoustic
properties
FDA Regulatory Roadmap
Research and
Development
Pre-Clinical
Development
Clinical
Testing
FDA 510(k)
Approval
Concept
Design Control
Design
Iterations
Repeatability
Testing
Submit 510(k)
Package
FDA Review
& QuestionsPackaging &
Labeling
Biocompatability
Repeatability
Testing
Electrical &
Mechanical
Testing
Repeatability
Testing
IRB/IDE
Approval
Neo-adjuvant
Chemo Trial
12weeks
~100 Patients
Human
Factor Study
~50-75
Users
Efficacy
Best Case Scenario:
Class II 510(k) no clinical study
• Predicate found already
• Expected clearance 5-6mo
• Need 50 users for usability
Validation Development
Worst Case Scenario:
Class II 510(k) DeNovo
- Expected clearance 10-
12mo
- Need 100+ users for clinical
Efficacy
We’re
Here
Screening Today
Self Breast Exam Mammogram
Insurance Covers >50
Ultrasound
$500
MRI
$ 2000
Go-to-market Timeline
✔ Q3
2015
✔ ✔ Q1 Q2 Q3 Q4Q4
2016
✔✔
2017
✔ Q1 Q2
2018
Partnerships
iSono Health’s compact, low-cost, automated ultrasound system
enables Remote Patient Monitoring for:
Neoadjuvent
Chemo
Patients, BC
Clinical Trials
Tracking Response to
Treatment
Personalized
Treatment
Early Stage BC
Patient
Post-Lumpectomy
Recurrence
Monitoring
Breast Conserving
Surgeries
High Risk
Women with
Family History,
Genetics
Surveillance Early Stage Detection
Healthy
Women with
Dense Breasts
Supplemental
Screening
False-
Negative/Positive
Reduction
Customer Validation
In a national survey of 1000
women, 38% have responded
favorably to purchasing our
device
"Amazing idea. Anything that
can give anyone a more
sound piece of mind or the
ability to see something
sooner is a great tool."
"Please keep me informed of
the details of this product."
"I'm very excited about this
being a viable option for
preventative screening!"
"I would be excited to have
access to a device like this. I
live in a rural area with little
access to Healthcare. I have
been diagnosed with BRCA1
mutated gene … this would
help me be proactive."
68% of high-risk women self-
reported as “very/extremely
willing” to purchase our
device
Device
Machine
LearningCloud
iSono IP Strategy
- Array Architecture
Transducer Assembly
- 3D Image Processing
-Tag and Measure
Breast Masses
-Track changes over
time
- User Interface
- Scan Analytics
- Genetic + Scan
Actionable
Cost ~ 5-10K
Current Ultrasound Trends: Cheaper, Automated
SonoSite PhilipsGE VSCAN MobiSante
Image Quality is
Operator DependentGE Invenia
(Acquired U Systems)
Siemens
ACUSON S2000
SonoCine
Cost ~ $200-400K
35.7% More Cancer Detected with Automated Breast Ultrasound*
Compact Ultrasound Probe Systems
Sources: MarketsandMarkets, Frost and Sullivan
*http://www.fdanews.com/articles/164936-ge-healthcare-nabs-fda-approval-of-invenia-abus-breast-imaging-technology
How Does it Work?
Comfortably wear
the bra accessory.
Attach scanner to ring
on either breast.
Open iSono app
press “scan.”
The scan completes in
1 minute.
Attach device to
the second ring on
the other breast.
Our software will
process images and
tag any changes.
Physician receives your
tagged images & sends
you feedback via the app.
The app will remind
you of the next scan
in 1 month.
Real Time Data
Real Time Feedback
Faster Return to Work
Less time in hospital/healthcare facilities  reduced cost
Post surgery monitoring
"Empowering Consumer with Smart Devices and Smart Data for Proactive ‘Health Care’" - Maryam Ziaei (Founder/CEO, iSono Health)

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"Empowering Consumer with Smart Devices and Smart Data for Proactive ‘Health Care’" - Maryam Ziaei (Founder/CEO, iSono Health)

  • 1.
  • 3. Patient- Centered Healthcar e HOSPITA L HOME Personalized What’s the best care for my needs? Predictive What health trends that are likely to develop? Proactive Who’s at risk? Who needs to be informed? Preventative What actions can I take now to prevent disease?
  • 4. Proactive Personalized Health: Move to LEFT Health Status 80% of Cost from 20% of Population
  • 5.
  • 6. Personalized Medical Home Smart Sensing Intelligent Information Management Effective Interfaces Putting the patient at the center of their health system Family & Friends Healthcare Providers Web Repositories Healthcare Institutions Researchers
  • 9. Smart Devices • Non-invasive wearable sensors • Personal biosensors • Environmental sensors • New data streams + machine learning = “New vital signs”
  • 14. Consumer Technologies Social Media Technologies Internet Technologies Visualisation Technologies Learning Technologies Enabling Technologies From glasses to wearables VLE PLE Collective intelligence Collaborative environments Next gen batteries Wireless power Tablet Quantified self 3D printing Information Visualisation Drivers of Disruption in Healthcare
  • 17. Machine Learning Tags Abnormalities Human-Centered Design Adoption + Adherence Human Nature Admires Complexity but Rewards Simplicity.
  • 18. Effective Interfaces • Multimodal – GUI, touch, gesture, speech, … • Mobile – Portable, networked, wearable • Intuitive – Easy to learn, use, maintain • Adaptive • Proactive
  • 19. Machine Learning Tags Abnormalities Security Privacy Compliance
  • 20. Machine Learning Tags Abnormalities > 400 Million Units by 2020
  • 21. Machine Learning Tags Abnormalities Patient Generated Data  Big Data
  • 22. Intelligent Information Management • Longitudinal data – Personal baseline – Detect trends & deviations from norm • Personal health records – Privacy – Sharing – Anonymous aggregation • Patient-centered decision support
  • 23. Data Aggregation and Analytics
  • 25. From Data to Decisions
  • 27. Machine Learning Tags Abnormalities EARLY ENAGEMENT = SUCCESS in Healthcare
  • 28. 28
  • 30.
  • 31. 1 in 8 women WILL BE DIAGNOSED WITH BREAST CANCER
  • 32. Machine Learning Tags Abnormalities EARLY DETECTION = 99% SURVIVAL
  • 33. 1 in 3 BREAST CANCERS IS MISSED
  • 34. 47% of women have dense breasts BUT Mammogram misses tumors in dense breasts Breast Cancer screening is sporadic, inaccessible, and expensive High risk women need more regular screening
  • 35. Current Breast Ultrasound Sources: American Cancer Society, American College of Radiology Image Quality is Operator Dependent False Positive
  • 36. Cost ~ 5-10K SonoSite PhilipsGE VSCAN GE Siemens Cost ~ $200-400K 35.7% More Cancer Detected with Automated Breast Ultrasound * Point-of-Care Automated
  • 38. Machine Learning Tags Abnormalities
  • 39. Machine Learning Detect Changes EARLY and Track Over Time
  • 40. 2 Minutes Scan  No Radiation  Actionable Feedback
  • 41. Clinical Study with 100 Women iSono GE
  • 42. Early Adopters Market of $4B CAGR of 10.8% Pricing: $300/Device $20/User/M onth ARR US Market 8.6M Women at Very High Risk Total Addressable Market of $32B 102M Women over 30 in US
  • 43. Early Stage Diagnosis $20K pp Late Stage Diagnosis $100-300K pp $18.5B Direct Cost of Breast Cancer + $14B Lost Productivity Per Year for self-insured employers and health insurance companies Why Would Payers Care?
  • 44. 44 Regular and Accessible Breast Health Monitoring $32B Market
  • 46. Making Sense of Big Data • Understanding human behavior from sensor data – Integrating vastly different kinds of data – Incorporating commonsense knowledge – Compute intensive methods for learning & inference • Embedded, mobile, and distributed systems – Data transport in dynamic, heterogeneous environments – Security and data sharing – Data / annotation / interpretation streams
  • 47.
  • 48.
  • 49. 49 System Concept Personal Health Monitoring • Preventative Healthcare • Chronic Care Management • Post-surgery Monitoring • Borrow from the field of machine health monitoring – Identify the most minimally invasive ways to capture data – Mine collected data to identify personal baselines, data defined models and track changes – Identify patient preferences and create a system that gives a valuable user experience – Identify effective ways to share data with health care providers Measure • Cardiac function (ECG) • Respiration (Sound/ECG) • Activity (Accelerometry) Alivetec ECG & motionTouch screen mobile phone
  • 50. Personal Health Management Assistant • Provide effective, intuitive access to information in Personal Health Record • True conversational interaction – UR Computer Science leading center of research on dialog systems – Not just canned responses: reasons about user model and dialog context • Target population: Heart failure patients following self-care guidelines – Collect information relevant to condition – Interpret with respect to self-care guidelines – Suggest appropriate course of action – Facilitate information sharing with doctors & family
  • 51.
  • 53. Go-to-Market Strategy High Risk Women Surveillance Women over 30 Screening Channels & Partners • Women Healthcare Centers • BC Advocacy Groups • Genetic Testing/Counseling • Corporate Wellness • Mail-in-Subscription • Walk-in Health Clinics Breast Cancer Patient Monitoring • Breast Cancer Centers • BC Pharma
  • 54. 1Billion Women need additional screening 50M Women at Very High Risk due to Family History or Genetics Every Year 1.7M New Cases of Breast Cancer Market Over 500,000 Breast Cancer Deaths/year
  • 55. Competitive Landscape Portable Ultrasound Automated Ultrasound 35% More Cancers Detected Cost: $200K + Wearable Sensor Solutions Cost: $5-10K Disadvantage: Probe Operator Error
  • 56. 1Billion Women over 30 in the World with Dense Breasts 50M Women at Very High Risk due to Family History or Genetics Every Year 1.7M New Cases of Breast Cancer Market Over 500,000 Breast Cancer Deaths/year
  • 57. Early Adopters Market of $4B CAGR of 10.8% Pricing: $300/Device $20/User/M onth ARR US Market 8.6M Women at Very High Risk Total Addressable Market of $32B 102M Women over 30 in US
  • 58. European Market Every Year 500,000 New Cases of Breast Cancer Over 140,000 Breast Cancer Deaths/year 14M Women at Very High Risk due to Family History or Genetics Early Adopters Market of $8B
  • 59. Women with Dense Breasts Sporadic and Inaccessible Screening High Risk Women
  • 60. Current Breast Cancer Screening Self Breast Exam Ineffective for small tumors Mammogram Low Sensitivity X-ray Radiation
  • 61. 1Billion Women over 30 in the World with Dense Breasts 50M Women at Very High Risk due to Family History or Genetics Every Year 1.7M New Cases of Breast Cancer Global Market Over 500,000 Breast Cancer Deaths/year
  • 62. Quantitative Ultrasound + Machine Learning • A multi-parameter longitudinal approach improves precision Grayscale Image Qualitative features • Shape • Contour • Shadow Raw RF signal Quantitative features • Power spectrum • Statistics • Frequency dependence Parametric Change Longitudinal features • Volume density • Cell death/growth • Tissue acoustic properties
  • 63. FDA Regulatory Roadmap Research and Development Pre-Clinical Development Clinical Testing FDA 510(k) Approval Concept Design Control Design Iterations Repeatability Testing Submit 510(k) Package FDA Review & QuestionsPackaging & Labeling Biocompatability Repeatability Testing Electrical & Mechanical Testing Repeatability Testing IRB/IDE Approval Neo-adjuvant Chemo Trial 12weeks ~100 Patients Human Factor Study ~50-75 Users Efficacy Best Case Scenario: Class II 510(k) no clinical study • Predicate found already • Expected clearance 5-6mo • Need 50 users for usability Validation Development Worst Case Scenario: Class II 510(k) DeNovo - Expected clearance 10- 12mo - Need 100+ users for clinical Efficacy We’re Here
  • 64. Screening Today Self Breast Exam Mammogram Insurance Covers >50 Ultrasound $500 MRI $ 2000
  • 65. Go-to-market Timeline ✔ Q3 2015 ✔ ✔ Q1 Q2 Q3 Q4Q4 2016 ✔✔ 2017 ✔ Q1 Q2 2018
  • 66. Partnerships iSono Health’s compact, low-cost, automated ultrasound system enables Remote Patient Monitoring for: Neoadjuvent Chemo Patients, BC Clinical Trials Tracking Response to Treatment Personalized Treatment Early Stage BC Patient Post-Lumpectomy Recurrence Monitoring Breast Conserving Surgeries High Risk Women with Family History, Genetics Surveillance Early Stage Detection Healthy Women with Dense Breasts Supplemental Screening False- Negative/Positive Reduction
  • 67. Customer Validation In a national survey of 1000 women, 38% have responded favorably to purchasing our device "Amazing idea. Anything that can give anyone a more sound piece of mind or the ability to see something sooner is a great tool." "Please keep me informed of the details of this product." "I'm very excited about this being a viable option for preventative screening!" "I would be excited to have access to a device like this. I live in a rural area with little access to Healthcare. I have been diagnosed with BRCA1 mutated gene … this would help me be proactive." 68% of high-risk women self- reported as “very/extremely willing” to purchase our device
  • 68. Device Machine LearningCloud iSono IP Strategy - Array Architecture Transducer Assembly - 3D Image Processing -Tag and Measure Breast Masses -Track changes over time - User Interface - Scan Analytics - Genetic + Scan Actionable
  • 69. Cost ~ 5-10K Current Ultrasound Trends: Cheaper, Automated SonoSite PhilipsGE VSCAN MobiSante Image Quality is Operator DependentGE Invenia (Acquired U Systems) Siemens ACUSON S2000 SonoCine Cost ~ $200-400K 35.7% More Cancer Detected with Automated Breast Ultrasound* Compact Ultrasound Probe Systems Sources: MarketsandMarkets, Frost and Sullivan *http://www.fdanews.com/articles/164936-ge-healthcare-nabs-fda-approval-of-invenia-abus-breast-imaging-technology
  • 70. How Does it Work? Comfortably wear the bra accessory. Attach scanner to ring on either breast. Open iSono app press “scan.” The scan completes in 1 minute. Attach device to the second ring on the other breast. Our software will process images and tag any changes. Physician receives your tagged images & sends you feedback via the app. The app will remind you of the next scan in 1 month.
  • 71. Real Time Data Real Time Feedback Faster Return to Work Less time in hospital/healthcare facilities  reduced cost Post surgery monitoring

Notas do Editor

  1. 1 in 3 breast cancers are missed at early stage by current screening methods.
  2. 1 in 3 breast cancers are missed at early stage by current screening methods.
  3. 1 in 3 breast cancers are missed at early stage by current screening methods.
  4. 1 in 3 breast cancers are missed at early stage by current screening methods.
  5. Opportunities with consumer-based home healthcare devices Connected devices Transform big data into information that delivers insights Simply user experience with Human-centered design
  6. Opportunities with consumer-based home healthcare devices Connected devices Transform big data into information that delivers insights Simply user experience with Human-centered design
  7. Opportunities with consumer-based home healthcare devices Connected devices Transform big data into information that delivers insights Simply user experience with Human-centered design
  8. Opportunities with consumer-based home healthcare devices Connected devices Transform big data into information that delivers insights Simply user experience with Human-centered design
  9. Opportunities with consumer-based home healthcare devices Connected devices Transform big data into information that delivers insights Simply user experience with Human-centered design
  10. Opportunities with consumer-based home healthcare devices Connected devices Transform big data into information that delivers insights Simply user experience with Human-centered design
  11. Opportunities with consumer-based home healthcare devices Connected devices Transform big data into information that delivers insights Simply user experience with Human-centered design
  12. Opportunities with consumer-based home healthcare devices Connected devices Transform big data into information that delivers insights Simply user experience with Human-centered design
  13. Opportunities with consumer-based home healthcare devices Connected devices Transform big data into information that delivers insights Simply user experience with Human-centered design
  14. 1 in 3 breast cancers are missed at early stage by current screening methods.
  15. 1 in 3 breast cancers are missed at early stage by current screening methods.
  16. 1 in 3 breast cancers are missed at early stage by current screening methods.
  17. Hi, I’m Maryam, co-founder of iSono health, we have developed a platform to empower every woman to take charge of their own health with a connected breast health monitoring platform
  18. Our platform combined automated ultrasound technology with Artificial Intelligence and Cloud Computation to regularly monitoring and tracking breast health over time, for early detection of breast cancer.
  19. When I was in college my friend Kelly was diagnosed with breast cancer. She wasn’t even 30…She was lucky her cancer was caught at early stage and after treatment now she’s healthy and has a kind. Every year 1.7 Million women get diagnosed globally with breast cancer, 500,000 here europe. Many of them are not as lucky.
  20. 1 in 3 breast cancers are missed at early stage by current screening methods.
  21. You might ask why? That’s because nearly half of women half dense tissues in their breast that makes mammogram ineffective. On the top right here you can see how a dense breast looks like in a mammogram, it effectively masks any small tumors. A great alternative to mammogram is Ultrasound. However ultrasound is not used today as screening tool, b/c it’s slow, images are operator dependent and has high false positives. Beyond that women who are at high risk of breast cancer due to family history or genetics need more regular screening but breast cancer screening today is only once a year, its expensive and inconvenient.
  22. we are making a disruption by making it lower  cost and bring it in the hand of consumer Regular monitoring 
  23. Smartphones and other personal mobile devices are one of the main drivers as to why the consumer health monitoring device market will grow, the research report states. According to IMS, there is a wealth of mobile health apps, allowing users to transfer readings from a medical device, which can then be stored and displayed on the device, or uploaded to a cloud-based system. This is possible, the researchers say, by buying independent devices from companies such as A&D Medical which utilize wireless technologies such as ANT+ or Bluetooth. Measurements from these devices can be viewed and stored locally, on devices such as smart phones, or uploaded to independent cloud-based systems.  “Many consumers already utilize smartphone apps to track their own health and fitness results, with devices such as activity monitors and heart-rate monitors. Now, there is increasing availability of health-related peripheral devices such as blood pressure monitors to track and upload information in real time via a wireless or wired connection to devices such as smartphones and tablets,” Arrowsmith says. The report looks at 10 connectivity technologies in five consumer health monitoring devices, five types of dedicated health hub (with addition segmentation between managed telehealth devices and consumer medical devices), and five sports and fitness monitoring devices. Around the World: Nearly 1.7 million new breast cancer cases were diagnosed in 2012. Breast cancer is the second most common cancer in women and men worldwide. In 2012, it represented about 12 percent of all new cancer cases and 25 percent of all cancers in women. Breast cancer is the most frequently diagnosed cancer among women in 140 of 184 countries worldwide. Globally, breast cancer now represents one in four of all cancers in women.  Since 2008, worldwide breast cancer incidence has increased by more than 20 percent. Mortality has increased by 14 percent. ​According to the World Cancer Research Fund International
  24. Smartphones and other personal mobile devices are one of the main drivers as to why the consumer health monitoring device market will grow, the research report states. According to IMS, there is a wealth of mobile health apps, allowing users to transfer readings from a medical device, which can then be stored and displayed on the device, or uploaded to a cloud-based system. This is possible, the researchers say, by buying independent devices from companies such as A&D Medical which utilize wireless technologies such as ANT+ or Bluetooth. Measurements from these devices can be viewed and stored locally, on devices such as smart phones, or uploaded to independent cloud-based systems.  “Many consumers already utilize smartphone apps to track their own health and fitness results, with devices such as activity monitors and heart-rate monitors. Now, there is increasing availability of health-related peripheral devices such as blood pressure monitors to track and upload information in real time via a wireless or wired connection to devices such as smartphones and tablets,” Arrowsmith says. The report looks at 10 connectivity technologies in five consumer health monitoring devices, five types of dedicated health hub (with addition segmentation between managed telehealth devices and consumer medical devices), and five sports and fitness monitoring devices. Around the World: Nearly 1.7 million new breast cancer cases were diagnosed in 2012. Breast cancer is the second most common cancer in women and men worldwide. In 2012, it represented about 12 percent of all new cancer cases and 25 percent of all cancers in women. Breast cancer is the most frequently diagnosed cancer among women in 140 of 184 countries worldwide. Globally, breast cancer now represents one in four of all cancers in women.  Since 2008, worldwide breast cancer incidence has increased by more than 20 percent. Mortality has increased by 14 percent. ​According to the World Cancer Research Fund International
  25. Breast Cancer has likely affected everyone in this room one way and another. We want to make sure no woman dies from breast cancer and put the power back into the hands of consumer. WE have the smart technology to do this Come see a demo and join us to save lives.
  26. 1 in 3 breast cancers are missed at early stage by current screening methods.
  27. 1 in 3 breast cancers are missed at early stage by current screening methods.
  28. 1 in 3 breast cancers are missed at early stage by current screening methods.
  29. 1 in 3 breast cancers are missed at early stage by current screening methods.
  30. 1 in 3 breast cancers are missed at early stage by current screening methods.
  31. Smartphones and other personal mobile devices are one of the main drivers as to why the consumer health monitoring device market will grow, the research report states. According to IMS, there is a wealth of mobile health apps, allowing users to transfer readings from a medical device, which can then be stored and displayed on the device, or uploaded to a cloud-based system. This is possible, the researchers say, by buying independent devices from companies such as A&D Medical which utilize wireless technologies such as ANT+ or Bluetooth. Measurements from these devices can be viewed and stored locally, on devices such as smart phones, or uploaded to independent cloud-based systems.  “Many consumers already utilize smartphone apps to track their own health and fitness results, with devices such as activity monitors and heart-rate monitors. Now, there is increasing availability of health-related peripheral devices such as blood pressure monitors to track and upload information in real time via a wireless or wired connection to devices such as smartphones and tablets,” Arrowsmith says. The report looks at 10 connectivity technologies in five consumer health monitoring devices, five types of dedicated health hub (with addition segmentation between managed telehealth devices and consumer medical devices), and five sports and fitness monitoring devices. Around the World: Nearly 1.7 million new breast cancer cases were diagnosed in 2012. Breast cancer is the second most common cancer in women and men worldwide. In 2012, it represented about 12 percent of all new cancer cases and 25 percent of all cancers in women. Breast cancer is the most frequently diagnosed cancer among women in 140 of 184 countries worldwide. Globally, breast cancer now represents one in four of all cancers in women.  Since 2008, worldwide breast cancer incidence has increased by more than 20 percent. Mortality has increased by 14 percent. ​According to the World Cancer Research Fund International
  32. Wearable medical devices defined in the strictest sense are devices with sensors attached to the body that detect and monitor changes in body signatures of various areas and organs. This report focuses on the various segments of wearable devices currently available in the market and also predicts the introduction of several innovative devices in the future. http://www.transparencymarketresearch.com/wearable-medical-devices.html
  33. Smartphones and other personal mobile devices are one of the main drivers as to why the consumer health monitoring device market will grow, the research report states. According to IMS, there is a wealth of mobile health apps, allowing users to transfer readings from a medical device, which can then be stored and displayed on the device, or uploaded to a cloud-based system. This is possible, the researchers say, by buying independent devices from companies such as A&D Medical which utilize wireless technologies such as ANT+ or Bluetooth. Measurements from these devices can be viewed and stored locally, on devices such as smart phones, or uploaded to independent cloud-based systems.  “Many consumers already utilize smartphone apps to track their own health and fitness results, with devices such as activity monitors and heart-rate monitors. Now, there is increasing availability of health-related peripheral devices such as blood pressure monitors to track and upload information in real time via a wireless or wired connection to devices such as smartphones and tablets,” Arrowsmith says. The report looks at 10 connectivity technologies in five consumer health monitoring devices, five types of dedicated health hub (with addition segmentation between managed telehealth devices and consumer medical devices), and five sports and fitness monitoring devices. Around the World: Nearly 1.7 million new breast cancer cases were diagnosed in 2012. Breast cancer is the second most common cancer in women and men worldwide. In 2012, it represented about 12 percent of all new cancer cases and 25 percent of all cancers in women. Breast cancer is the most frequently diagnosed cancer among women in 140 of 184 countries worldwide. Globally, breast cancer now represents one in four of all cancers in women.  Since 2008, worldwide breast cancer incidence has increased by more than 20 percent. Mortality has increased by 14 percent. ​According to the World Cancer Research Fund International
  34. Smartphones and other personal mobile devices are one of the main drivers as to why the consumer health monitoring device market will grow, the research report states. According to IMS, there is a wealth of mobile health apps, allowing users to transfer readings from a medical device, which can then be stored and displayed on the device, or uploaded to a cloud-based system. This is possible, the researchers say, by buying independent devices from companies such as A&D Medical which utilize wireless technologies such as ANT+ or Bluetooth. Measurements from these devices can be viewed and stored locally, on devices such as smart phones, or uploaded to independent cloud-based systems.  “Many consumers already utilize smartphone apps to track their own health and fitness results, with devices such as activity monitors and heart-rate monitors. Now, there is increasing availability of health-related peripheral devices such as blood pressure monitors to track and upload information in real time via a wireless or wired connection to devices such as smartphones and tablets,” Arrowsmith says. The report looks at 10 connectivity technologies in five consumer health monitoring devices, five types of dedicated health hub (with addition segmentation between managed telehealth devices and consumer medical devices), and five sports and fitness monitoring devices. Around the World: Nearly 1.7 million new breast cancer cases were diagnosed in 2012. Breast cancer is the second most common cancer in women and men worldwide. In 2012, it represented about 12 percent of all new cancer cases and 25 percent of all cancers in women. Breast cancer is the most frequently diagnosed cancer among women in 140 of 184 countries worldwide. Globally, breast cancer now represents one in four of all cancers in women.  Since 2008, worldwide breast cancer incidence has increased by more than 20 percent. Mortality has increased by 14 percent. ​According to the World Cancer Research Fund International
  35. Smartphones and other personal mobile devices are one of the main drivers as to why the consumer health monitoring device market will grow, the research report states. According to IMS, there is a wealth of mobile health apps, allowing users to transfer readings from a medical device, which can then be stored and displayed on the device, or uploaded to a cloud-based system. This is possible, the researchers say, by buying independent devices from companies such as A&D Medical which utilize wireless technologies such as ANT+ or Bluetooth. Measurements from these devices can be viewed and stored locally, on devices such as smart phones, or uploaded to independent cloud-based systems.  “Many consumers already utilize smartphone apps to track their own health and fitness results, with devices such as activity monitors and heart-rate monitors. Now, there is increasing availability of health-related peripheral devices such as blood pressure monitors to track and upload information in real time via a wireless or wired connection to devices such as smartphones and tablets,” Arrowsmith says. The report looks at 10 connectivity technologies in five consumer health monitoring devices, five types of dedicated health hub (with addition segmentation between managed telehealth devices and consumer medical devices), and five sports and fitness monitoring devices. Around the World: Nearly 1.7 million new breast cancer cases were diagnosed in 2012. Breast cancer is the second most common cancer in women and men worldwide. In 2012, it represented about 12 percent of all new cancer cases and 25 percent of all cancers in women. Breast cancer is the most frequently diagnosed cancer among women in 140 of 184 countries worldwide. Globally, breast cancer now represents one in four of all cancers in women.  Since 2008, worldwide breast cancer incidence has increased by more than 20 percent. Mortality has increased by 14 percent. ​According to the World Cancer Research Fund International
  36. You might ask why? That’s because screening is sporadic and inaccessible to millions of women worldwide. And among those who have access to screening, mammogram doesn’t work for half of women who have dense breasts due to to limitations of xray technology. Furthermore, women who have family history or genetically predisposed need even more frequent screening. These three groups of women consitute our different costumer segments. A great alternative to mammogram is Ultrasound. However ultrasound is not used today as screening tool, b/c it’s slow, images are operator dependent and has high false positives. Beyond that women who are at high risk of breast cancer due to family history or genetics need more regular screening but breast cancer screening today is only once a year, its expensive and inconvenient.
  37. 1 in 8 women will be diagnosed with invasive breast cancer in their lifetime Every 3 minutes a woman is diasnosed with breast cancer Every 13 minutes a woman dies from breast cancer >400,000 Deaths per year from Breast Cancer Early detection can increase the 10 year survival rate to 97% Mammogram, which is the primary screening tool, cannot detect cancer in dense breast tissue (~50% of women) Insurance cover mammogram screening for women above 50 Women with high risk have 60-80% chance of breast cancer  require regular monitoring If you have a first degree relative who was diagnosed with breast cancer your chances are two times higher. If you have two relatives who were diagnosed, your chances are 5x higher Some women with high risk such as Angelina Jolie resort to double-mastectomy Even with double mastectomy, you have to constantly monitor your breast/breast area as cancerous cell still can develop
  38. Smartphones and other personal mobile devices are one of the main drivers as to why the consumer health monitoring device market will grow, the research report states. According to IMS, there is a wealth of mobile health apps, allowing users to transfer readings from a medical device, which can then be stored and displayed on the device, or uploaded to a cloud-based system. This is possible, the researchers say, by buying independent devices from companies such as A&D Medical which utilize wireless technologies such as ANT+ or Bluetooth. Measurements from these devices can be viewed and stored locally, on devices such as smart phones, or uploaded to independent cloud-based systems.  “Many consumers already utilize smartphone apps to track their own health and fitness results, with devices such as activity monitors and heart-rate monitors. Now, there is increasing availability of health-related peripheral devices such as blood pressure monitors to track and upload information in real time via a wireless or wired connection to devices such as smartphones and tablets,” Arrowsmith says. The report looks at 10 connectivity technologies in five consumer health monitoring devices, five types of dedicated health hub (with addition segmentation between managed telehealth devices and consumer medical devices), and five sports and fitness monitoring devices. Around the World: Nearly 1.7 million new breast cancer cases were diagnosed in 2012. Breast cancer is the second most common cancer in women and men worldwide. In 2012, it represented about 12 percent of all new cancer cases and 25 percent of all cancers in women. Breast cancer is the most frequently diagnosed cancer among women in 140 of 184 countries worldwide. Globally, breast cancer now represents one in four of all cancers in women.  Since 2008, worldwide breast cancer incidence has increased by more than 20 percent. Mortality has increased by 14 percent. ​According to the World Cancer Research Fund International
  39. 1 in 8 women will be diagnosed with invasive breast cancer in their lifetime Every 3 minutes a woman is diasnosed with breast cancer Every 13 minutes a woman dies from breast cancer >400,000 Deaths per year from Breast Cancer Early detection can increase the 10 year survival rate to 97% Mammogram, which is the primary screening tool, cannot detect cancer in dense breast tissue (~50% of women) Insurance cover mammogram screening for women above 50 Women with high risk have 60-80% chance of breast cancer  require regular monitoring If you have a first degree relative who was diagnosed with breast cancer your chances are two times higher. If you have two relatives who were diagnosed, your chances are 5x higher Some women with high risk such as Angelina Jolie resort to double-mastectomy Even with double mastectomy, you have to constantly monitor your breast/breast area as cancerous cell still can develop ----- Meeting Notes (10/19/16 14:52) ----- insurance
  40. Change colors of arrows
  41. 1 in 3 breast cancers are missed at early stage by current screening methods.