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TYPES OF DRUG FOR
MUSCULOSKELETEL
   DISORDERS
MUSCLE RELAXANT

NAME OF        BRAND     INDICATION             SIDE EFFECT        CONTRA            DOSAGE
DRUG(GENE      NAME                                                INDICATION
RIC NAME)
Carisoprodol   Vanadom   skeletal muscle        side effects       history of        Tablets, USP
/Soma                    relaxant used to       occur: fainting;   acute             350 mg are
                         relax certain          fast heartbeat;    intermittent      White
                         muscles in your        fever; hive-like   porphyria or a
                         body and relieve       swellings on       hypersensitivit
                         the problems           face, eyelids,     y reaction to a
                         caused by              mouth, lips,       carbamate
                         strains, sprains, or   and/or tongue;     such as
                         other muscular         mental             meprobamate
                         injuries. Soma         depression;
                         works in the           shortness of
                         Central Nervous        breath.
                         System (CNS).
NAME OF        BRAND     INDICATION          SIDE EFFECT         CONTRA              DOSAGE
DRUG           NAME                                              INDICATION
(GENERIC
NAME)
Orphenadrine   Norflex   Orphenadrine        Drowsiness,         Contraindicated     TABLETS: Adults
Injection                citrate is          dizziness,          in patients with    Two tablets per
                         indicated as an     lightheadedness     glaucoma,           day; one in the
                         adjunct to rest,    , blurred vision,   pyloric or          morning and
                         physical            vision changes,     duodenal            one in the
                         therapy, and        headache,           obstruction,        evening.
                         other measures      stomach upset,      stenosing peptic    INJECTION:
                         for the relief of   dry mouth, or       ulcers, prostatic   Adults 2 mL
                         discomfort          constipation        hypertrophy or      ampul (60 mg)
                         associated with                         obstruction of      intravenously or
                         acute painful                           the bladder         intramuscularly;
                         musculo                                 neck, cardio-       may be
                         skeletal                                spasm               repeated every
                         conditions                              (megaesophagu       12 hours. Relief
                                                                 s) and              may be
                                                                 myasthenia          maintained by 1
                                                                 gravis.             Norflex
                                                                                     Extended-
                                                                                     release Tablet
                                                                                     twice daily.
NAME OF    BRAND    INDICATION      SIDE EFFECT       DOSAGE             CONTRA
DRUG       NAME                                                          INDICATION
(GENERIC
NAME )
Diazepam   Valium   used to treat   confusion,        Oral: 2 to 10      Ataxia,Severe
                    anxiety         hallucinations    mg 3 to 4          hypoventilatio
                    disorders,      , unusual         times a day.       n,Acute
                    alcohol         thoughts or       IM or IV: 5 to     narrow-angle
                    withdrawal      behavior;unus     10 mg initially,   glaucoma.Live
                    symptoms, or    ual risk-taking   then 5 to 10       rdisorders,Sev
                    muscle          behavior,         mg in 3 to 4       ere
                    spasms. It is   decreased         hours, if          respiratory
                    sometimes       inhibitions, no   necessary. For     disorders,Sev
                    used with       fear of           tetanus,           ere
                    other           danger;depre      larger doses       depression,
                    medications     ssed mood         may be             particularly
                    to treat                          required.          when
                    seizures.                                            accompanied
                                                                         by suicidal
                                                                         tendencies,Pr
                                                                         egnancy or
                                                                         breast feeding
NAME OF    BRAND        INDICATION    SIDE EFFECT     CONTRA         DOSAGE
DRUG       NAME                                       INDICATION
(GENERIC
NAME)
Panadol    Acetaminop   Relief of     Most people     Hypersensiti   Adults,
extend     hen          backaches,    taking          vity to        Children ≥12
                        mild to       Panadol         paracetamol    years and
                        moderate      Extend find     or to any of   Elderly: 2
                        joint pains   that it does    the            caplets
                        and           not cause       excipient,     every 8 hrs
                        muscular      problems.       Renal and      (maximum:
                        aches eg,     However,        hepatic        6 caplets in
                        sprains,      occasionally    failure        24 hrs). Do
                        strains and   some                           not chew or
                        sports        people may                     crush
                        injuries.     get allergic                   caplets.
                                      reactions
                                      eg, skin rash
NAME OF     BRAND     INDICATION       SIDE EFFECT       CONTRA           DOSAGE
DRUG        NAME                                         INDICATION
(GENERIC
NAME)
Methocarbam Robaxin   This             Stomach           Coma or pre-     500 mg –
ol                    medication       upset,            coma states,     Adults: Initial
                      relaxes          nausea,           brain damage,    dosage, 3
                      muscles. It is   flushing,         myasthenia       tablets q.i.d.;
                      used along       constipation,     gravis. Do not   maintenance
                      with rest and    headache,         admin            dosage, 2
                      physical         blurred vision,   parentral        tablets q.i.d.
                      therapy to       lightheadedne     solution in      750 mg –
                      decrease         ss, dizziness     patients with    Adults: Initial
                      muscle pain      or drowsiness     renal            dosage, 2
                      and spasms                         impairment,      tablets q.i.d.;
                      associated                         epilepsy or      maintenance
                      with strains,                      history of       dosage, 1
                      sprains or                         epilepsy.        tablet q.4h. or
                      other muscle                                        2 tablets t.i.d
                      injuries.
ANTI RHEUMATOID DRUGS
GENERIC BRAND DOSAGE INDICATION SIDE                  CONTRAIN
NAME    NAME                    EFFECT                DICATION
1.ALLOP ZYLORI Initial   •Gout or       •Skin rash    •Hypersens
URINOL C       :100-     uric acid      •GI upset     itivity to
               300mg     •Calcium       •Peripheral   allupurinol
               daily     oxalate        neuritis      •Pregnancy
               Maintan   •Renal stone                 •Lactation
               ence :
               300-
               600mg
               daily
               Max :
               900mg
               daily
GENERIC    BRAND DOSAGE       INDICATI   SIDE EFFECT CONTRAI
NAME       NAME               ON                     NDICATIO
                                                     N

2.CELECO   CELEBR Adult :   •Osteoatri •GI disoder   •Allergic
XIB        EX     a)200mg/d tis        •Flatulence   reaction
                  aily      •Rheumat •Insomnia       to aspirin
                            oid        •Sinustis     •Hypersen
                            Arthritis •Dizziness     sitivity to
                            •Acute                   celecoxib
                            pain
GENERIC     BRAND   DOSAGE             INDICATION      SIDE EFFECT    CONTRAINDI
NAME        NAME                                                      CATION



3.MELOXIC   MOBIC   •Initially 7.5mg   •Painful        •Dyspepsia     •Active
AM                  daily may          osteoarthriti   •Nausea        peptic
                    increased to       s               •Abdo pain     ulceration
                    15mg daily         •Rheumatoid     •Skin rash     •Pregnancy
                    •Intially 15mg     arthritis       •Constipatio   •Lactation
                    daily may                          n
                    decrease to                        •Pruitis
                    7.5mg daily
                    •Max 15mg
                    daily
GENERIC    BRAND    DOSAGE        INDICATIO      SIDE          CONTRAIN
NAME       NAME                   N              EFFECT        DICATION




4.NAPROXE NAPROS •0.5-1 g daily   •Rheumato      •GI           •Hypersens
N         YN     in 2 divided     id arthritis   disturbanc    itivity
                 dose             •Osteoarth     e             •Allergic
                 •750mg           ritis          •Vertigo      reaction to
                 initially then   •Acute         •GI           aspirin or
                 250mg 8hrly      gout           ulceration    other anti-
                 •500mg           •Muscular      •Dizziness    inflammat
                 initially then   skeletal       •Hearing      ory drugs
                 250mg every      disorder       disturbanc
                 6-8hr                           e
                                                 •Fluid
                                                 retentation
DRUG FOR BONE DISORDER
GENERIC   BRAND    DOSAGE     INDICATI     SIDE         CONTRAI
NAME      NAME                ON           EFFECT       NDICATIO
                                                        N

1.ALENDR FOSAMAX   5-10 mg    osteoporo    •Nausea,     Pregnancy
ONATE              daily or   sis in men   vomiting     Breastfee
                   35-70 mg   and          bloating     ding
                   weekly     postmeno     •Constipat   Renal
                              pausal       ion          impairme
                              women.       •Diarrhea    nt
                                           •black
                                           stool
GENERIC BRAND        DOSAGE     INDICATI SIDE          CONTRAIND
NAME    NAME                    ON       EFFECT        ICATION


2.Etidron Didronel   400 mg       Osteopor Diarrhea,   Osteoporosi
ate                  orally daily osis     nausea,     s with
                                           headache,   hypercalcae
                                           stomach     mia/hyperca
                                           upset       lciuria
Gene Brand        Dosage         Indication     Side effect Contraind
ric  name                                                   ication
name
3.Cal Rocaltrol   Calcitriol     •Predialysis   •Weakness     Patient
citriol           can be         Patients       •Headache     with
                  administere    •Dialysis      •Nausea       hypercalc
                  d orally       Patients       •Vomiting     emia and
                  either as a    •Hypoparat     •Dry          evidence
                  capsule        hyroidism      mouth         of of
                  (0.25 mcg or   Patients       •Constipati   vitamin D
                  0.50 mcg) or                  on            toxicity.
                  as an oral
                  solution (1
                  mcg/mL).
Generic    Brand        Dosage Indication    Side        Contrain
name       name                              effect      dication

4.Evista   Raloxifene   1 tablet Treament &    Hot      •Venous
                        daily(60 Prevention of flushes   Thrombo
                        mg)      osteoporosis Leg       embolis
                                 in post       cramp     m
                                 menopausal Periph      •Pregnan
                                 woman         eral      cy
                                               edema     Women
                                               Venous
                                               thromem
                                               bolitic
Musculoskeletel drug

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Musculoskeletel drug

  • 1. TYPES OF DRUG FOR MUSCULOSKELETEL DISORDERS
  • 2. MUSCLE RELAXANT NAME OF BRAND INDICATION SIDE EFFECT CONTRA DOSAGE DRUG(GENE NAME INDICATION RIC NAME) Carisoprodol Vanadom skeletal muscle side effects history of Tablets, USP /Soma relaxant used to occur: fainting; acute 350 mg are relax certain fast heartbeat; intermittent White muscles in your fever; hive-like porphyria or a body and relieve swellings on hypersensitivit the problems face, eyelids, y reaction to a caused by mouth, lips, carbamate strains, sprains, or and/or tongue; such as other muscular mental meprobamate injuries. Soma depression; works in the shortness of Central Nervous breath. System (CNS).
  • 3. NAME OF BRAND INDICATION SIDE EFFECT CONTRA DOSAGE DRUG NAME INDICATION (GENERIC NAME) Orphenadrine Norflex Orphenadrine Drowsiness, Contraindicated TABLETS: Adults Injection citrate is dizziness, in patients with Two tablets per indicated as an lightheadedness glaucoma, day; one in the adjunct to rest, , blurred vision, pyloric or morning and physical vision changes, duodenal one in the therapy, and headache, obstruction, evening. other measures stomach upset, stenosing peptic INJECTION: for the relief of dry mouth, or ulcers, prostatic Adults 2 mL discomfort constipation hypertrophy or ampul (60 mg) associated with obstruction of intravenously or acute painful the bladder intramuscularly; musculo neck, cardio- may be skeletal spasm repeated every conditions (megaesophagu 12 hours. Relief s) and may be myasthenia maintained by 1 gravis. Norflex Extended- release Tablet twice daily.
  • 4. NAME OF BRAND INDICATION SIDE EFFECT DOSAGE CONTRA DRUG NAME INDICATION (GENERIC NAME ) Diazepam Valium used to treat confusion, Oral: 2 to 10 Ataxia,Severe anxiety hallucinations mg 3 to 4 hypoventilatio disorders, , unusual times a day. n,Acute alcohol thoughts or IM or IV: 5 to narrow-angle withdrawal behavior;unus 10 mg initially, glaucoma.Live symptoms, or ual risk-taking then 5 to 10 rdisorders,Sev muscle behavior, mg in 3 to 4 ere spasms. It is decreased hours, if respiratory sometimes inhibitions, no necessary. For disorders,Sev used with fear of tetanus, ere other danger;depre larger doses depression, medications ssed mood may be particularly to treat required. when seizures. accompanied by suicidal tendencies,Pr egnancy or breast feeding
  • 5. NAME OF BRAND INDICATION SIDE EFFECT CONTRA DOSAGE DRUG NAME INDICATION (GENERIC NAME) Panadol Acetaminop Relief of Most people Hypersensiti Adults, extend hen backaches, taking vity to Children ≥12 mild to Panadol paracetamol years and moderate Extend find or to any of Elderly: 2 joint pains that it does the caplets and not cause excipient, every 8 hrs muscular problems. Renal and (maximum: aches eg, However, hepatic 6 caplets in sprains, occasionally failure 24 hrs). Do strains and some not chew or sports people may crush injuries. get allergic caplets. reactions eg, skin rash
  • 6. NAME OF BRAND INDICATION SIDE EFFECT CONTRA DOSAGE DRUG NAME INDICATION (GENERIC NAME) Methocarbam Robaxin This Stomach Coma or pre- 500 mg – ol medication upset, coma states, Adults: Initial relaxes nausea, brain damage, dosage, 3 muscles. It is flushing, myasthenia tablets q.i.d.; used along constipation, gravis. Do not maintenance with rest and headache, admin dosage, 2 physical blurred vision, parentral tablets q.i.d. therapy to lightheadedne solution in 750 mg – decrease ss, dizziness patients with Adults: Initial muscle pain or drowsiness renal dosage, 2 and spasms impairment, tablets q.i.d.; associated epilepsy or maintenance with strains, history of dosage, 1 sprains or epilepsy. tablet q.4h. or other muscle 2 tablets t.i.d injuries.
  • 7. ANTI RHEUMATOID DRUGS GENERIC BRAND DOSAGE INDICATION SIDE CONTRAIN NAME NAME EFFECT DICATION 1.ALLOP ZYLORI Initial •Gout or •Skin rash •Hypersens URINOL C :100- uric acid •GI upset itivity to 300mg •Calcium •Peripheral allupurinol daily oxalate neuritis •Pregnancy Maintan •Renal stone •Lactation ence : 300- 600mg daily Max : 900mg daily
  • 8. GENERIC BRAND DOSAGE INDICATI SIDE EFFECT CONTRAI NAME NAME ON NDICATIO N 2.CELECO CELEBR Adult : •Osteoatri •GI disoder •Allergic XIB EX a)200mg/d tis •Flatulence reaction aily •Rheumat •Insomnia to aspirin oid •Sinustis •Hypersen Arthritis •Dizziness sitivity to •Acute celecoxib pain
  • 9. GENERIC BRAND DOSAGE INDICATION SIDE EFFECT CONTRAINDI NAME NAME CATION 3.MELOXIC MOBIC •Initially 7.5mg •Painful •Dyspepsia •Active AM daily may osteoarthriti •Nausea peptic increased to s •Abdo pain ulceration 15mg daily •Rheumatoid •Skin rash •Pregnancy •Intially 15mg arthritis •Constipatio •Lactation daily may n decrease to •Pruitis 7.5mg daily •Max 15mg daily
  • 10. GENERIC BRAND DOSAGE INDICATIO SIDE CONTRAIN NAME NAME N EFFECT DICATION 4.NAPROXE NAPROS •0.5-1 g daily •Rheumato •GI •Hypersens N YN in 2 divided id arthritis disturbanc itivity dose •Osteoarth e •Allergic •750mg ritis •Vertigo reaction to initially then •Acute •GI aspirin or 250mg 8hrly gout ulceration other anti- •500mg •Muscular •Dizziness inflammat initially then skeletal •Hearing ory drugs 250mg every disorder disturbanc 6-8hr e •Fluid retentation
  • 11. DRUG FOR BONE DISORDER GENERIC BRAND DOSAGE INDICATI SIDE CONTRAI NAME NAME ON EFFECT NDICATIO N 1.ALENDR FOSAMAX 5-10 mg osteoporo •Nausea, Pregnancy ONATE daily or sis in men vomiting Breastfee 35-70 mg and bloating ding weekly postmeno •Constipat Renal pausal ion impairme women. •Diarrhea nt •black stool
  • 12. GENERIC BRAND DOSAGE INDICATI SIDE CONTRAIND NAME NAME ON EFFECT ICATION 2.Etidron Didronel 400 mg Osteopor Diarrhea, Osteoporosi ate orally daily osis nausea, s with headache, hypercalcae stomach mia/hyperca upset lciuria
  • 13. Gene Brand Dosage Indication Side effect Contraind ric name ication name 3.Cal Rocaltrol Calcitriol •Predialysis •Weakness Patient citriol can be Patients •Headache with administere •Dialysis •Nausea hypercalc d orally Patients •Vomiting emia and either as a •Hypoparat •Dry evidence capsule hyroidism mouth of of (0.25 mcg or Patients •Constipati vitamin D 0.50 mcg) or on toxicity. as an oral solution (1 mcg/mL).
  • 14. Generic Brand Dosage Indication Side Contrain name name effect dication 4.Evista Raloxifene 1 tablet Treament & Hot •Venous daily(60 Prevention of flushes Thrombo mg) osteoporosis Leg embolis in post cramp m menopausal Periph •Pregnan woman eral cy edema Women Venous thromem bolitic