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Mµng tÕ bµo

TÕ bµo chÊt

Nh©n
NhiÔm s¾c
thÓ

ADN
S¬ ®å cÊu tróc ph©n tö ADN
Cña James W
atson vµ Francis crick

CÊu tróc ph©n tö ADN: chuçi xo¾ n kÐp
gåm 2 m¹ch ®¬n. Nhê c«ng tr×nh nµy mµ
hai «ng nhËn ®­îc gi¶i th­ëng N«-ben vÒ y
häc vµ sinh lý häc n¨m 1962.
Thµnh phÇn ho¸ häc cña ADN

C : C¸c bon
H : Hi ®r«
O : ¤ xi
N : Ni t¬
P : Phèt pho
so s¸nh khèi l­îng ph© tö cña mét sè chÊt
n
ChÊt

Khèi l­îng ph©n tö

Axit Sunfuric
H2SO4

98 ®vC

Hªm«gl«bin
C3032H4816O372S8Fe4

68000 ®vC
Dµi kho¶ng 0,1 micromet

ADN

150000000 ®vC
Dµi hµng tr¨m micromet
c¸c ®¬n ph©n cña ADN
A
G
T
X
T
A
G
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T
A
G
X
X
T
A
G

T
X
A
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A
T
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G
A
T
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G
A
T
X

A-®ª-nin
Ti-min
Gu-a-nin
Xy-t«-zin
Thµnh phÇn cña mét nuclª«tit
H3PO4
§­êng §ªzoxiribo
Bazo nitric
A
c¸c ®¬n ph©n cña ADN
A
G
T
X
T
A
G
X
T
A
G
X
X
T
A
G

T
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A
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A
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A
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TÝnh ®a d¹ng vµ ®Æc thï cña ADN
T

T

T

T

G

X
G

T

T
A

G

X

X

X

X

T
A

T
A

T
A

G

X
G

T
A

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T

G

T

G

X

T

Do cÊu t¹o theo nguyªn t¾c ® ph© c¸c A ND
a
n,
® tr ­ng bëi sè l­îng, thµnh phÇn vµ trËt tù
Æc
s¾p xÕp cña c¸c nuclª«tit tr ong ph© tö.
n
TÕ bµo mÑ
TÕ bµo mÑ

K× trung gian
TÕ bµo mÑ

K× trung gian

K× ®
Çu
TÕ bµo mÑ

K× gi÷a

K× trung gian

K× ®
Çu
TÕ bµo mÑ

K× gi÷a

K× trung gian

K× sau

K× ®
Çu
TÕ bµo mÑ

K× gi÷a

K× trung gian

K× sau

K× ®
Çu

K× cuèi
TÕ bµo mÑ

K× gi÷a

K× trung gian

K× sau

K× ®
Çu

K× cuèi
TÕ bµo mÑ

K× gi÷a

K× trung gian

K× sau

K× ®
Çu

K× cuèi
TÕ bµo mÑ

K× gi÷a

K× trung gian

K× sau

K× ®
Çu

Hai tÕ bµo con
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A
G

T
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A
G

A
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T
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A
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A
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A
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A
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G
X

T
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G
X
A
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A
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A
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A
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A
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T

A
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T
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A
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T
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A
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T
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Tèc ®é tæng hîp: kho¶ 100 Nuclª«tit mét gi©y
ng
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Tèc ®é tæng hîp: kho¶ 100 Nuclª«tit mét gi©y
ng
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kh¸i niÖn gen?
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A

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Th«ng tin qui
®Þnh lo¹i Pr«tit
A

TÝnh tr¹ng A

Th«ng tin qui
®Þnh lo¹i Pr«tit
B

TÝnh tr¹ng B

T

X

X
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T

A

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kh¸i niÖm gen?
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A
G

Lµ mét ®o¹n cña ph©n tö ADN mang
th«ng tin qui ®Þnh cÊu tróc cña mét lo¹i
Pr«tit.

T

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Lµ mét ®o¹n cña ph©n tö ADN mang
th«ng tin qui ®Þnh cÊu tróc cña mét lo¹i
Pr«tit.
10
9
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5
4
3
2
1
0

Cho §o¹n m¹ch ®¬n mÉu
H·y t×m ® t­¬ng øng: 1, 2 hay 3?
o¹n
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MÉu

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1

2

3
Bµi tËp

Mét ®o¹n ADN chøa 10000 Nu clª«tit c¸c
lo¹i. Sè nuclª«tit lo¹i A (A-®ª-nin) nhiÒu h¬n
sè nuclª«tit lo¹i X (Xi-t«-zin) lµ 1000.
TÝnh sè Nuclª«tit mçi lo¹i trong ®o¹n ADN
®ã?

?
Bµi tËp
Sè nuclª«tit lo¹i T trong ®
o¹n A DN lµ 450.
Tr ong mét m¹ch ® cña ®
¬n
o¹n A DN ® cã 4
ã
lo¹i nuclª«tit A – T – G – X cã tØ lÖ lÇn l­ît lµ
1 : 2 : 3 : 4.
TÝnh sè nuclª«tit mçi lo¹i trong ® A DN ®
o¹n
ã?
Khi tù sao 1 lÇn, ® A DN nµy cÇn bao nhiªu
o¹n
nuclª«tit tù do trong m«i tr­êng néi bµo?

?
Bµi tËp

Trong qu¸ tr×nh tù sao, mét ®o¹n ADN sö
dông hÕt 2000 Nuclª«tit lo¹i A trong m«i
tr-êng néi bµo. Sè nuclª«tit lo¹i X chiÕm
30% tæng sè Nuclª«tit tù do ®· sö dông.
TÝnh tæng sè Nuclª«tit cña ®o¹n ADN
®ã?

?
Lùa chän ch­a chÝnh x¸c!
xin mét trµng vç tay an ñi?
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Lùa chän chÝnh x¸c _ ®iÓm: 9 phÈy 5

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Lùa chän ch­a chÝnh x¸c!
xin mét trµng vç tay an ñi?
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