USO DE ANTIHIPERTENSIVOS EN IRC

1. USO DE ANTIHIPERTENSIVOS EN IRC MC EDILBERTO IBAÑEZ BURGOS SERVICIO DE NEFROLOGIA HNAAA CHICLAYO-PERU

4. Adapted from JNC VII or >100 >160 Stage 2 hypertension or 90-99 140-159 Stage 1 hypertension or 80-89 120-139 Prehypertension and <80 <120 Normal Diastolic BP, mm Hg Systolic BP, mm Hg Classification of Blood Pressure (JNC VII)

5. DASH = Dietary Approaches to Stop Hypertension Adapted from JNC VII 2-4 mm Hg Limit consumption to no more than 2 drinks per day in most men and no more than 1 drink per day in women and in lighter weight persons. Moderation of alcohol consumption 4-9 mm Hg (at least 30 minutes/day, most days of the week) Physical activity 2-8 mm Hg (2.4 g sodium or 6 g sodium chloride) Dietary sodium reduction 8-14 mm Hg fruits, vegetables, and dairy products with a reduced content of saturated and total fat (K,Ca) Adopt DASH eating plan 5-20 mm Hg/ 10 kg weight loss IMC:18.4-24.9 kg/m 2 Weight reduction Approximate SBP Reduction Range Recommendation Modification LIFESTYLE MODIFICATIONS TO MANAGE HYPERTENSION *†

6. PROGRESS X X RECURRENT STROKE PREVENTION NKF GUIDELINE, CAPTOPRIL TRIAL, RENAAL, IDNT, REIN, AASK X X CHRONIC KIDNEY DISEASE NKF-ADA Guideline, UKPDS, ALLHAT X X X X X DIABETES ALLHAT, HOPE, ANBP2, LIFE, CONVINCE X X X X HIGH CORONARY DISEASE RISK ACC/AHA Post-MI Guideline, BHAT, SAVE, Capricorn, EPHESUS X X X POSTMYOCARDIAL INFARCTION ACC/AHA Heart Failure Guideline, MERIT-HF, COPERNICUS, CIBIS, SOLVD, AIRE, TRACE, ValHEFT, RALES X X X X X HEART FAILURE AANT BCC ARA IECA BB D Clinical Trial Basis ‡ Recommended Drugs † Compelling Indication* Clinical Trial and Guideline Basis for Compelling Indications for Individual Drug Classes

29. ß-Adrenergic Blockers: * Medications are listed is alphabetical, not preferential order. carvedilol, labetalol Nonselective ß- and α- antagonists acebutolol ß 1 -selective with partial agonist activity atenolol, betaxolol, bisoprolol, metoprolol ß 1 -selective carteolol, penbutolol, pindolol Nonselective with partial agonist activity nadolol, propranolol, timolol Nonselective ß-adrenergic blockers Medication* Drug Class ß-Adrenergic Blockers

39. Calcium Channel Blockers:

44. Calcium Channel Blockers

59. Angiotensin-Converting Enzyme Inhibitors

62. Angiotensin II Receptor Blockers

77. Central α2-Agonists

90. GRACIAS