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Dr. Steven R.
Goldstein MD
The Burden of Osteoporosis,
Osteoporosis, Poor Bone
Health, and Fragility
Fractures
WWW.GOLDSTEINMD.COM 1
WWW.GOLDSTEINMD.COM 2
Dr Steven R. Goldstein MD is an Osteoporosis
Specialist in NYC and a leading Menopause
Specialist in NYC. For more than 25 years he has
helped women cope with the symptoms of
menopause. Menopausal women are also at risk
for Osteoporosis, poor bone health and fragility
fractures
WWW.GOLDSTEINMD.COM 3
In Dr Goldstein’s office almost all women are
cognizant of breast health, have a great fear of
breast cancer, and for the most part are attuned to
the importance of competent periodic breast
imaging… the key to earliest detection.
WWW.GOLDSTEINMD.COM 4
The goal is not to have a better DXA at age 82, the goal is
to not break a hip at age 82
Bone health IS more than just osteoporosis. Dr
Goldstein’s hope is to get these same patients to be just
as concerned about their bone health as they are
concerned about their breast health. He compiled some
statistics which will help you to understand how
important bone health, osteoporosis and fragility
fractures are to you as you pursue HEALTHY aging!
WWW.GOLDSTEINMD.COM 5
The Burden of Osteoporosis, Poor
Bone Health and Fragility Fractures
Worldwide, osteoporosis causes more than 8.9
million fractures annually, resulting in an
osteoporotic fracture every three seconds. I
Johnell O, Kanis JA. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporosis Int. 2006;17:1726–1733.
WWW.GOLDSTEINMD.COM 6
The Burden of Osteoporosis, Poor
Bone Health and Fragility Fractures
It is estimated that osteoporosis effects 200
million women worldwide. One-tenth of women
aged 60, one-fifth of women aged 70, two-fifths of
women aged 80 and, two-thirds of women aged
90 carry this diagnosis. ii
ii Kanis, JA, Odén A, McCloskey EV, et al. A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporosis Int. 2012;23:2239–2256.
WWW.GOLDSTEINMD.COM 7
The Burden of Osteoporosis, Poor
Bone Health and Fragility Fractures
It is estimated that osteoporosis effects 200
million women worldwide. One-tenth of women
aged 60, one-fifth of women aged 70, two-fifths of
women aged 80 and, two-thirds of women aged
90 carry this diagnosis. ii
ii Kanis, JA, Odén A, McCloskey EV, et al. A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporosis Int. 2012;23:2239–2256.
It is estimated that osteoporosis
effects 200 million women
worldwide. One-tenth of women
aged 60, one-fifth of women aged
70, two-fifths of women aged 80
and, two-thirds of women aged 90
carry this diagnosis. ii
WWW.GOLDSTEINMD.COM 8
ii Kanis, JA, Odén A, McCloskey EV, et al. A systematic review of hip fracture incidence and
probability of fracture worldwide. Osteoporosis Int. 2012;23:2239–2256.
Worldwide, one in three women
after the age 50 will experience
osteoporotic fracture. iii
iii Adult Official Positions of the ISCD as updated in 2019. www.iscd.org.
Last accessed July 2021
WWW.GOLDSTEINMD.COM 10
The Burden of Osteoporosis, Poor
Bone Health and Fragility Fractures
At menopause, the removal of estrogen has much greater
effects in women than men of similar age. The female-to-male
ratio of osteoporotic fractures is approximately 1.6, such that
80% of forearm fractures, 75% of humerus fractures, 70% of
hip fractures, and 58% of spine fractures occur in women. iv
iv Johnell O, Kanis JA. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporosis Int. 2006;17:1726–1733.
WWW.GOLDSTEINMD.COM 11
The Burden of Osteoporosis, Poor
Bone Health and Fragility Fractures
A prior fracture is associated with an 86% increased risk of any
subsequent fracture. V
v Kanis JA, Johansson H, Harvey NC, et al. A brief history of FRAX. Arch Osteoporos. 2018;13(1):118
.
Fragility fractures are a leading
cause of chronic disease
morbidity. For instance, in
Europe, fragility fractures are the
fourth leading cause, after
ischemic heart disease,
dementia, and lung cancer;
however, they surpass chronic
obstructive pulmonary disease
and ischemic stroke. vi
vi Kanis JA, Johansson H, Strom O, et al. The National Osteoporosis Guideline
Group. Case finding for the management of osteoporosis with FRAX® –
assessment and intervention thresholds for the UK. Osteoporos Int. 2008;19:1395–
1408.
After sustaining a
hip fracture, 10-
20% of formerly
community-
dwelling patients
require long-
term nursing
care.vii
vii Bone HG, Wagman RG, Brandi ML, et al. 10 years of
denosumab treatment in postmenopausal women with
osteoporosis: results from the phase 3 randomised FREEDOM
trial and open-label extension. Lancet Diabetes Endocrinol.
2017;5:513–523.
Overall, hip fractures cause the
most morbidity, and reported
mortality rates in up to 20-24% in
the first year after a hip fracture.
viii
viii Goodpaster BH, Park SW, Harris TB, et al. The loss of skeletal muscle strength, mass, and quality in older adults: The health,
aging and body composition study. J Gerontol A Biol Sci Med Sci. 2006;61:1059–1064.
Loss of function and
independence among
survivors is profound,
with 40% unable to
walk independently,
and 60% require
assistance a year later.
ix
ix Anker SD, Morley JE, von Haehling S, et al. Welcome to the ICD-10 code for
sarcopenia. J Cachexia Sarcopenia Muscle. 2026;7(5):512–514.
WWW.GOLDSTEINMD.COM 16
CONTRAST THE ABOVE WITH
BREAST CANCER
• In localized breast cancer where there is no sign that the cancer has
spread outside the breast, the 5-year survival in the US is 99%! (American
Cancer Society. Survival Rates for Breast Cancer. Available at:
https://www.cancer.org/cancer/breast-cancer/understanding-a-breast-
cancer-diagnosis/breast-cancer-survival-rates.html )
• Even regional breast cancer, defined as spread outside the breast to
nearby structures or lymph nodes, has an 86% five-year survival.
(American Cancer Society. Survival Rates for Breast Cancer. Available at:
https://www.cancer.org/cancer/breast-cancer/understanding-a-breast-
cancer-diagnosis/breast-cancer-survival-rates.html )
In developed countries where
women have access to periodic
competent breast screening by
imaging techniques, for many the
diagnosis of localized breast cancer
and the psychological ramifications
may exceed the physical
manifestations.
You only need contrast the statistics
above vis a vis breast cancer versus the
statistics cited about the incidence,
morbidity and even mortality associated
with osteoporosis and fragility fractures
(ESPECIALLY of the hip) to see the
importance of bone health and
osteoporosis
314 East 34th Street 5th Floor
New York, NY 10016
Call: 212.717.5554
Visit us: www.goldsteinmd.com
Dr. Steven R. Goldstein MD
One of America’s Top Gynecologists

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Dr Steven R. Goldstein - Osteoporosis, Poor Bone Health, Fragility Fractures

  • 1. Dr. Steven R. Goldstein MD The Burden of Osteoporosis, Osteoporosis, Poor Bone Health, and Fragility Fractures WWW.GOLDSTEINMD.COM 1
  • 2. WWW.GOLDSTEINMD.COM 2 Dr Steven R. Goldstein MD is an Osteoporosis Specialist in NYC and a leading Menopause Specialist in NYC. For more than 25 years he has helped women cope with the symptoms of menopause. Menopausal women are also at risk for Osteoporosis, poor bone health and fragility fractures
  • 3. WWW.GOLDSTEINMD.COM 3 In Dr Goldstein’s office almost all women are cognizant of breast health, have a great fear of breast cancer, and for the most part are attuned to the importance of competent periodic breast imaging… the key to earliest detection.
  • 4. WWW.GOLDSTEINMD.COM 4 The goal is not to have a better DXA at age 82, the goal is to not break a hip at age 82 Bone health IS more than just osteoporosis. Dr Goldstein’s hope is to get these same patients to be just as concerned about their bone health as they are concerned about their breast health. He compiled some statistics which will help you to understand how important bone health, osteoporosis and fragility fractures are to you as you pursue HEALTHY aging!
  • 5. WWW.GOLDSTEINMD.COM 5 The Burden of Osteoporosis, Poor Bone Health and Fragility Fractures Worldwide, osteoporosis causes more than 8.9 million fractures annually, resulting in an osteoporotic fracture every three seconds. I Johnell O, Kanis JA. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporosis Int. 2006;17:1726–1733.
  • 6. WWW.GOLDSTEINMD.COM 6 The Burden of Osteoporosis, Poor Bone Health and Fragility Fractures It is estimated that osteoporosis effects 200 million women worldwide. One-tenth of women aged 60, one-fifth of women aged 70, two-fifths of women aged 80 and, two-thirds of women aged 90 carry this diagnosis. ii ii Kanis, JA, Odén A, McCloskey EV, et al. A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporosis Int. 2012;23:2239–2256.
  • 7. WWW.GOLDSTEINMD.COM 7 The Burden of Osteoporosis, Poor Bone Health and Fragility Fractures It is estimated that osteoporosis effects 200 million women worldwide. One-tenth of women aged 60, one-fifth of women aged 70, two-fifths of women aged 80 and, two-thirds of women aged 90 carry this diagnosis. ii ii Kanis, JA, Odén A, McCloskey EV, et al. A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporosis Int. 2012;23:2239–2256.
  • 8. It is estimated that osteoporosis effects 200 million women worldwide. One-tenth of women aged 60, one-fifth of women aged 70, two-fifths of women aged 80 and, two-thirds of women aged 90 carry this diagnosis. ii WWW.GOLDSTEINMD.COM 8 ii Kanis, JA, Odén A, McCloskey EV, et al. A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporosis Int. 2012;23:2239–2256.
  • 9. Worldwide, one in three women after the age 50 will experience osteoporotic fracture. iii iii Adult Official Positions of the ISCD as updated in 2019. www.iscd.org. Last accessed July 2021
  • 10. WWW.GOLDSTEINMD.COM 10 The Burden of Osteoporosis, Poor Bone Health and Fragility Fractures At menopause, the removal of estrogen has much greater effects in women than men of similar age. The female-to-male ratio of osteoporotic fractures is approximately 1.6, such that 80% of forearm fractures, 75% of humerus fractures, 70% of hip fractures, and 58% of spine fractures occur in women. iv iv Johnell O, Kanis JA. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporosis Int. 2006;17:1726–1733.
  • 11. WWW.GOLDSTEINMD.COM 11 The Burden of Osteoporosis, Poor Bone Health and Fragility Fractures A prior fracture is associated with an 86% increased risk of any subsequent fracture. V v Kanis JA, Johansson H, Harvey NC, et al. A brief history of FRAX. Arch Osteoporos. 2018;13(1):118 .
  • 12. Fragility fractures are a leading cause of chronic disease morbidity. For instance, in Europe, fragility fractures are the fourth leading cause, after ischemic heart disease, dementia, and lung cancer; however, they surpass chronic obstructive pulmonary disease and ischemic stroke. vi vi Kanis JA, Johansson H, Strom O, et al. The National Osteoporosis Guideline Group. Case finding for the management of osteoporosis with FRAX® – assessment and intervention thresholds for the UK. Osteoporos Int. 2008;19:1395– 1408.
  • 13. After sustaining a hip fracture, 10- 20% of formerly community- dwelling patients require long- term nursing care.vii vii Bone HG, Wagman RG, Brandi ML, et al. 10 years of denosumab treatment in postmenopausal women with osteoporosis: results from the phase 3 randomised FREEDOM trial and open-label extension. Lancet Diabetes Endocrinol. 2017;5:513–523.
  • 14. Overall, hip fractures cause the most morbidity, and reported mortality rates in up to 20-24% in the first year after a hip fracture. viii viii Goodpaster BH, Park SW, Harris TB, et al. The loss of skeletal muscle strength, mass, and quality in older adults: The health, aging and body composition study. J Gerontol A Biol Sci Med Sci. 2006;61:1059–1064.
  • 15. Loss of function and independence among survivors is profound, with 40% unable to walk independently, and 60% require assistance a year later. ix ix Anker SD, Morley JE, von Haehling S, et al. Welcome to the ICD-10 code for sarcopenia. J Cachexia Sarcopenia Muscle. 2026;7(5):512–514.
  • 16. WWW.GOLDSTEINMD.COM 16 CONTRAST THE ABOVE WITH BREAST CANCER
  • 17. • In localized breast cancer where there is no sign that the cancer has spread outside the breast, the 5-year survival in the US is 99%! (American Cancer Society. Survival Rates for Breast Cancer. Available at: https://www.cancer.org/cancer/breast-cancer/understanding-a-breast- cancer-diagnosis/breast-cancer-survival-rates.html ) • Even regional breast cancer, defined as spread outside the breast to nearby structures or lymph nodes, has an 86% five-year survival. (American Cancer Society. Survival Rates for Breast Cancer. Available at: https://www.cancer.org/cancer/breast-cancer/understanding-a-breast- cancer-diagnosis/breast-cancer-survival-rates.html )
  • 18. In developed countries where women have access to periodic competent breast screening by imaging techniques, for many the diagnosis of localized breast cancer and the psychological ramifications may exceed the physical manifestations.
  • 19. You only need contrast the statistics above vis a vis breast cancer versus the statistics cited about the incidence, morbidity and even mortality associated with osteoporosis and fragility fractures (ESPECIALLY of the hip) to see the importance of bone health and osteoporosis
  • 20. 314 East 34th Street 5th Floor New York, NY 10016 Call: 212.717.5554 Visit us: www.goldsteinmd.com Dr. Steven R. Goldstein MD One of America’s Top Gynecologists