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Cognitive Screening and
Clinical Decision Support
at a Distance
A presentation for the Georgia
Partnership for TeleHealth
March 15th 2012



                    Gregory Bayer, PhD
                    Brain Resource, Inc
New Technologies for Cognitive
                 Assessment and Remediation
Technologies Exist Today For Rapid Neuropsychological Screening
•   Psychiatric screening that can be done in under 10 minutes and at a distance with 85%
    sensitivity and 84% specificity for identifying risk across a broad spectrum of disorders.
•   Neuropsychological screening can be accomplished at home or in a clinic environment
    using a standardized and objective measure of emotional and cognitive skills plus self-
    reported measure of behavior in a 35 minute evaluation.
•   Brain health programs and biofeedback tools that can be used with minimal or no
    supervision at an individual’s own pace.


These technologies allow providers to:
•   Obtain neuropsychological evaluation quickly, efficiently, and inexpensively
•   Support psychiatric diagnosis and medication decisions with objective cognitive markers
•   Improve diagnostic accuracy, permitting more individualized biopsychosocial treatment
•   Assess and monitor psychotropic mediations more effectively
•   Augment rehabilitation activities with a self-administered brain-health improvement
    program.
Integrative Neuroscience Assessment
Scalable brain health assessments can be built from existing
neuropsychological batteries and deployed via the web for easy
administration and use.
Questions [Feeling and Self Regulation] (<5 min)

                                        “I Find it     “I respond best
                                       difficult to       to positive
                                         relax”            feedback”




Objective Cognitive Tasks [Emotion and Thinking] (30 min)




        Motor        Choice Reaction      Memory          Emotion         Digit Span      Verbal
       Tapping             Time          Recognition    Identification                 Interference




      Switching of     Go/No-Go          Delayed          Emotion         Continuous      Maze
       Attention                         Memory          Recognition     Performance
                                        Recognition                          Test
A Web-Based Model of Psychiatric Practice
Neurocognitive assessments and brain training exercises can be used in
combination to provide personalized assessment and treatment options.
                                         1.   Rapid Neurodiagonistic Screener
                    Brief Screening      2.   Identifies early risk for brain health condition
                                         3.   Broad spectrum screen with high sensitivity


       Assessment

                    Neuropsychological   1.   Objective & Rapid Assessment of strengths/deficits
                                         2.   Treatment decision support & change monitoring
                    Assessment           3.   Effective screener for ADHD, Depression, Dementia,
                                              TBI



                                         1.   Interactive Brain Training
                    Training Program     2.   Promotes Resilience
                                         3.   Remediates cognitive and emotional deficit areas


        Treatment

                    Biofeedback-based    1.   Heart Rate Variability training
                                         2.   Personalized Stress Management
                    stress management    3.   Adjunctive non-medicative therapy
BRISC For Mental Health Screening
BRISC (Brain Resource brain health screen) includes 15 questions to assess
Negative-Positive Bias, Emotional Resilience, and Social Skills
Helps identify individuals who have and/or are susceptible to a mental health
disorder.
Negativity Bias has 85% sensitivity an 84% specificity for identifying risk across a
broad spectrum of disorders.




                                                              Williams, Cooper, Wisniewski, Gatt, Koslow,
                                                              Kulkarni, Gordon, Rush (2011). Sensitivity,
                                                              specificity and predictive power of the “BRISC”, a
                                                              cross-sectional study on a brief web screen for
                                                              brain health. J Clinical Psychiatry (in review)
Cognitive Markers + Clinical Algorithms =
  Powerful Tools For Dx and Tx
1. Assess core cognitive and emotional capacities
2. Apply data-based clinical algorithms to individual responses
3. Use resulting clinical profile to support practice-at-a-distance
decision making
Example Reporting on Resilience and Self-Control
Example Reporting on Key Cognitive Domains
Testing Supports Case Identification,
Medication & Management
Sensitivity and specificity of
  web-based tests for ADHD

                                Sensitivity             Specificity

Markers from
• Sustained Attention
• Impulsivity
• Intrusions
• Inhibition
                               88% 91%
• Response Variability


                Williams LM, Using brain-based cognitive measures to support
         clinical decisions in ADHD. Pediatric Neurol. 2010 Feb;42(2):118-26.
CPT Code Information for Web-Based Testing

                 Neuropsychological tests for clinical use



     96116                   96118                    96119                   96120
 Neurobehavioral          Clinician time for     Technician time for       Non-facilitated
   Status Exam             facilitating test       facilitating test     test administration
 Clinician time for        administration          administration
interpreting results      Clinician time for                              Clinician time for
     and report          interpreting results     Clinician time for     interpreting results
Most reimbursed in                and            interpreting results         and report
telehealth settings              report               and report
                                                                         Medicare Payment
Medicare Payment         Medicare Payment        Medicare Payment           (Source: AMA
   (Source: AMA            (Source: AMA             (Source: AMA               Website)
      Website)                Website)                 Website)          Non-facility = $78.85
Non-facility = $72.61   Non-facility = $106.01   Non-facility = $72.89     Facility = $24.84
  Facility = $66.91       Facility = $85.75        Facility = $25.63
                                                                         ONE TIME CHARGE
     PER HOUR                PER HOUR                 PER HOUR
MyBrainSolutions.com Brain Training Experience

         Know Your Brain                           Train Your Brain                            Optimize Yourself
A brain assessment and report to discover   Interactive games and exercises designed      A dashboard with tools to monitor
your personal strengths/weaknesses and      based on proven techniques to develop brain   training results and progress towards
personalize your training.                  healthy habits.                               achieving health goals.
Behavioral Change with Fun Online Tools

 Traditional behavioral change strategies made fun and accessible.




Thought Challenger                 Relaxation Room                       Training with Positive                Positive Reflections
Learn about the connection         A meditation room allows user to      Affirmations helps Employees          Writing down at least one thing
between thoughts, feeling and      practice relaxation strategies like   develop positive self-talk in areas   that went well each day is a tactic
behaving by challenging specific   progressive muscle relaxation and     where they often have negative        to help strengthen our positive
negative thoughts and creating     slow breathing.                       thoughts or doubts. For ex. ‘I feel   memories. Positive Reflections
more productive thinking habits.                                         healthy and happy’ vs. ‘I know I’m    then encourages you to associate
                                                                         going to get sick soon’.              any event with a person strength of
                                                                                                               yours to build a sense of self
                                                                                                               efficacy – that you have the power
                                                                                                               to influence your outcomes each
                                                                                                               and every day.
Non-medication Stress Management

MyCalmBeat provides accessible, intuitive bio-feedback for members
to reduce stress, sharpen focus, and improve health outcomes
                                    2. Train using your iPhone, iPod Touch, iPad,
                                    Blackberry, Android and over the web.




                                                                                    Scie



                                    3. Train using biofeedback on your desktop.
Guides patients through 3 Stages:
   1. Identification of Optimal Breathing Rate
   2. Training
   3. Progress Monitoring
Thank you

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Cognitive Screening and Clinical Decision Support at a Distance

  • 1. Cognitive Screening and Clinical Decision Support at a Distance A presentation for the Georgia Partnership for TeleHealth March 15th 2012 Gregory Bayer, PhD Brain Resource, Inc
  • 2. New Technologies for Cognitive Assessment and Remediation Technologies Exist Today For Rapid Neuropsychological Screening • Psychiatric screening that can be done in under 10 minutes and at a distance with 85% sensitivity and 84% specificity for identifying risk across a broad spectrum of disorders. • Neuropsychological screening can be accomplished at home or in a clinic environment using a standardized and objective measure of emotional and cognitive skills plus self- reported measure of behavior in a 35 minute evaluation. • Brain health programs and biofeedback tools that can be used with minimal or no supervision at an individual’s own pace. These technologies allow providers to: • Obtain neuropsychological evaluation quickly, efficiently, and inexpensively • Support psychiatric diagnosis and medication decisions with objective cognitive markers • Improve diagnostic accuracy, permitting more individualized biopsychosocial treatment • Assess and monitor psychotropic mediations more effectively • Augment rehabilitation activities with a self-administered brain-health improvement program.
  • 3. Integrative Neuroscience Assessment Scalable brain health assessments can be built from existing neuropsychological batteries and deployed via the web for easy administration and use. Questions [Feeling and Self Regulation] (<5 min) “I Find it “I respond best difficult to to positive relax” feedback” Objective Cognitive Tasks [Emotion and Thinking] (30 min) Motor Choice Reaction Memory Emotion Digit Span Verbal Tapping Time Recognition Identification Interference Switching of Go/No-Go Delayed Emotion Continuous Maze Attention Memory Recognition Performance Recognition Test
  • 4. A Web-Based Model of Psychiatric Practice Neurocognitive assessments and brain training exercises can be used in combination to provide personalized assessment and treatment options. 1. Rapid Neurodiagonistic Screener Brief Screening 2. Identifies early risk for brain health condition 3. Broad spectrum screen with high sensitivity Assessment Neuropsychological 1. Objective & Rapid Assessment of strengths/deficits 2. Treatment decision support & change monitoring Assessment 3. Effective screener for ADHD, Depression, Dementia, TBI 1. Interactive Brain Training Training Program 2. Promotes Resilience 3. Remediates cognitive and emotional deficit areas Treatment Biofeedback-based 1. Heart Rate Variability training 2. Personalized Stress Management stress management 3. Adjunctive non-medicative therapy
  • 5. BRISC For Mental Health Screening BRISC (Brain Resource brain health screen) includes 15 questions to assess Negative-Positive Bias, Emotional Resilience, and Social Skills Helps identify individuals who have and/or are susceptible to a mental health disorder. Negativity Bias has 85% sensitivity an 84% specificity for identifying risk across a broad spectrum of disorders. Williams, Cooper, Wisniewski, Gatt, Koslow, Kulkarni, Gordon, Rush (2011). Sensitivity, specificity and predictive power of the “BRISC”, a cross-sectional study on a brief web screen for brain health. J Clinical Psychiatry (in review)
  • 6. Cognitive Markers + Clinical Algorithms = Powerful Tools For Dx and Tx 1. Assess core cognitive and emotional capacities 2. Apply data-based clinical algorithms to individual responses 3. Use resulting clinical profile to support practice-at-a-distance decision making
  • 7. Example Reporting on Resilience and Self-Control
  • 8. Example Reporting on Key Cognitive Domains
  • 9. Testing Supports Case Identification, Medication & Management
  • 10. Sensitivity and specificity of web-based tests for ADHD Sensitivity Specificity Markers from • Sustained Attention • Impulsivity • Intrusions • Inhibition 88% 91% • Response Variability Williams LM, Using brain-based cognitive measures to support clinical decisions in ADHD. Pediatric Neurol. 2010 Feb;42(2):118-26.
  • 11. CPT Code Information for Web-Based Testing Neuropsychological tests for clinical use 96116 96118 96119 96120 Neurobehavioral Clinician time for Technician time for Non-facilitated Status Exam facilitating test facilitating test test administration Clinician time for administration administration interpreting results Clinician time for Clinician time for and report interpreting results Clinician time for interpreting results Most reimbursed in and interpreting results and report telehealth settings report and report Medicare Payment Medicare Payment Medicare Payment Medicare Payment (Source: AMA (Source: AMA (Source: AMA (Source: AMA Website) Website) Website) Website) Non-facility = $78.85 Non-facility = $72.61 Non-facility = $106.01 Non-facility = $72.89 Facility = $24.84 Facility = $66.91 Facility = $85.75 Facility = $25.63 ONE TIME CHARGE PER HOUR PER HOUR PER HOUR
  • 12. MyBrainSolutions.com Brain Training Experience Know Your Brain Train Your Brain Optimize Yourself A brain assessment and report to discover Interactive games and exercises designed A dashboard with tools to monitor your personal strengths/weaknesses and based on proven techniques to develop brain training results and progress towards personalize your training. healthy habits. achieving health goals.
  • 13. Behavioral Change with Fun Online Tools Traditional behavioral change strategies made fun and accessible. Thought Challenger Relaxation Room Training with Positive Positive Reflections Learn about the connection A meditation room allows user to Affirmations helps Employees Writing down at least one thing between thoughts, feeling and practice relaxation strategies like develop positive self-talk in areas that went well each day is a tactic behaving by challenging specific progressive muscle relaxation and where they often have negative to help strengthen our positive negative thoughts and creating slow breathing. thoughts or doubts. For ex. ‘I feel memories. Positive Reflections more productive thinking habits. healthy and happy’ vs. ‘I know I’m then encourages you to associate going to get sick soon’. any event with a person strength of yours to build a sense of self efficacy – that you have the power to influence your outcomes each and every day.
  • 14. Non-medication Stress Management MyCalmBeat provides accessible, intuitive bio-feedback for members to reduce stress, sharpen focus, and improve health outcomes 2. Train using your iPhone, iPod Touch, iPad, Blackberry, Android and over the web. Scie 3. Train using biofeedback on your desktop. Guides patients through 3 Stages: 1. Identification of Optimal Breathing Rate 2. Training 3. Progress Monitoring