Power Point Presentation

1. What is Sarcoidosis?

2. It is an inflammatory disease
that primarily affects the lungs
and lymph nodes

3. It can also affect most any
other organ of the body

4. Other Body Organs Affected
kin
Uveitis
Lupus Pernio
Pemphigus Vulgaris

5. The exact cause is unknown
but
current consensus of etiology is
exposure to an unidentifiable
environmental agent that triggers
an immune response with
granuloma formation

6. Granuloma Formation

7. Signs & Symptoms
Most Common Initial
 Shortness of breath
 Dry cough that won’t go
away
 Reddish bumps or patches
on or under the skin
 Fever
 Weight loss
 Fatigue
 Night sweats
 Just ‘not feeling well’
Other disease characteristics
 Read and teary eyes or
blurred vision
 Swollen and painful joints
 Enlarge lymph glands in
the neck, armpits, and groin
 Nasal stuffiness, hoarse
voice
 Pain in hands,feet, or other
bony areas due to cysts
 Kidney stone formation
 Abnormal or missed heart
beats

8. Disease Progression
Inflammation Granuloma Fibrosis

9. Treatment Strategy:
Suppress
Inflammation
Reduce
impact of
granulomas
Prevent lung
fibrosis

10. Diagnosis: Hallmark sign =Granulomas
 Exclusion of other conditions
 Radiologic Imaging
 Cytologic/ Histologic results (biopsy)

11. Who is at Risk?
Sarcoidosis affects people of all ages and races.
 20-40 age group
 Women > Men
 African Americans > Caucasians (In the U.S.)
 Working in occupations that expose you to
environmental toxins

12. References
Cleveland Clinic Sarcodosis. (2015) Retrieved
from:
http://my.clevelandclinic.org/health/diseases_condit
ions/hic_Overview_of_Sarcoidosis
Mayfield, V., Sarcoidosis Project (2015) Maryland
University of Integrated Health, Laurel, Md.