What are the solutions that can help companies scale up inclusive business ventures? In this issue brief, the World Business Council for Sustainable Development (WBCSD) zooms in on the internal organizational barriers large companies face when trying to scale up inclusive business. However, the WBCSD did not limit itself to highlighting problems, but also identified solutions that have been put in place by WBCSD members to overcome those barriers. The issue brief features insights from CEMEX, Grundfos, ITC, Lafarge, Masisa, Nestlé, Novartis, Novozymes, SABMiller, Schneider Electric, and The Coca-Cola Company, and Vodafone. The brief organizes the range of possible internal organizational barriers to scale up inclusive business into three main categories: opportunity cost of investment; strategic and operational misalignment; capability gaps. For each of these three categories of barriers, the brief describes a range of solutions (a dozen in total) illustrated by company examples – from obtaining the support of senior leadership and establishing centers of excellence, to bringing core capabilities in-house, adjusting performance targets and quantifying the total value created by inclusive business ventures. This piece is a contribution to Action2020, the WBCSD platform for business to contribute solutions to environmental and social challenges.