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An Introduction to Intensity Modulated Radiotherapy PHY778 Lecture April 1, 2009
Outline ,[object Object],[object Object],[object Object],[object Object],[object Object]
Introduction ,[object Object],[object Object],[object Object],[object Object],Beamlet Field Width Field Length
Introduction ,[object Object],[object Object],[object Object],[object Object]
Introduction ,[object Object],[object Object]
Implementation
Process Patient Selection ↓ Simulation ↓ Target and Tissue Delineation ↓ Treatment Planning/Optimization ↓ Plan Evaluation ↓ Quality Assurance ↓ Treatment Delivery ↓ Followup
Patient Selection ,[object Object],[object Object],[object Object]
Patient Selection ,[object Object],[object Object],[object Object],Rx to 76 Gy  95%  50%
Patient Selection ,[object Object],[object Object],[object Object],[object Object]
Patient Selection ,[object Object],[object Object],[object Object],[object Object],[object Object]
Simulation ,[object Object],[object Object],[object Object]
Simulation ,[object Object],[object Object],[object Object],[object Object]
Simulation ,[object Object],[object Object],[object Object],[object Object],[object Object]
Simulation ,[object Object],[object Object],[object Object],[object Object]
Simulation ,[object Object]
Contouring ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Target Delineation ICRU 50, 62 ,[object Object],[object Object],[object Object],[object Object],[object Object]
PTV versus OAR ,[object Object]
Contouring ,[object Object]
Contouring example
Planning ,[object Object],[object Object],[object Object],[object Object]
Number and Placement of beams ,[object Object],[object Object],[object Object]
Planning ,[object Object],1 9 8 7 6 5 4 3 2 1 2 3 4 5 6 7
Beam number and placement ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Parallel Opposed Fields ,[object Object],[object Object],[object Object],[object Object],[object Object]
Beam number and placement ,[object Object]
Collimator Rotation ,[object Object],[object Object]
Objectives ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Objectives ,[object Object],[object Object],[object Object],[object Object]
Objectives- Max and Min dose Maximum = 50 Gy Minimum = 70 Gy
Objectives – Uniform dose Maximum Dose Maximum = 70 Gy Minimum = 70 Gy
Objectives – Dose volume objectives Maximum Dose > 70 Gy to 90% Target < 60 Gy to 10% OAR
Objectives – Equivalent Uniform Dose 43 49 30 71 EUD 7.4 Cord 4.6 Brainstem 5.0 Parotid -8.0 Target a Region
Physics ,[object Object]
Physics ,[object Object],[object Object],[object Object],[object Object]
Physics – optimization algorithms ,[object Object],[object Object],[object Object],[object Object],[object Object]
Physics – optimization algorithms ,[object Object],[object Object],[object Object]
Physics – Optimization in Eclipse ,[object Object]
Physics - optimization in Eclipse ,[object Object],[object Object]
Physics - optimization in Eclipse ,[object Object],[object Object]
Physics - optimization in Eclipse ,[object Object],[object Object],[object Object],[object Object]
Physics - optimization in Eclipse ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Physics - optimization in Pinnacle ,[object Object]
Physics - optimization in Pinnacle ,[object Object]
IMRT - optimization in practice ,[object Object],[object Object],[object Object]
IMRT - optimization in practice ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IMRT - optimization in practice ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IMRT - optimization in practice ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IMRT – radiation protection ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IMRT – MLC technical details ,[object Object],[object Object],[object Object],[object Object]
IMRT – MLC technical details ,[object Object]
IMRT – MLC technical details ,[object Object]
IMRT – MLC technical details ,[object Object]
IMRT – MLC transmission ,[object Object],[object Object],[object Object],[object Object]
IMRT – MLC dosimetric leaf gap ,[object Object],[object Object]
IMRT – MLC minimum dose dynamic leaf gap ,[object Object]
IMRT – MLC leaf speed ,[object Object],[object Object],[object Object],[object Object]
IMRT – Dose/Arc dynamic leaf tolerance ,[object Object]
IMRT – Jaw over travel ,[object Object]
IMRT – Leaf over travel ,[object Object]
IMRT – Leaf Positions ,[object Object],[object Object]
IMRT – Leaf Span ,[object Object],[object Object]
IMRT – Multiple carriage delivery ,[object Object],[object Object],[object Object]
Electronic compensation ,[object Object],[object Object],[object Object],[object Object]
Complete Irradiated Area Outline (CIAO) ,[object Object],[object Object]
IMRT QA – Ion chamber array ,[object Object],[object Object],[object Object]
IMRT QA Ion-chamber array
IMRT QA – Day 0 Pinnacle Fluence Map EPID image

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