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The following is a summary of certain 2008 projected financial information and metrics provided by Aetna on July 31, 2008. This
information is provided for reference only, and has not been updated. You should consider the information to speak only as of its
date of original publication. Aetna does not assume any responsibility to update the information to reflect subsequent events. Please
also refer to the Cautionary Statement; Additional Information below for additional information regarding important risk factors that
may affect the forward looking and other information in this document.

You should read this information in conjunction with Aetna’s earnings press release issued July 31, 2008 and should review the replay
of the related investor call in full, since the press release provides further discussion of Aetna’s results, and the investor call provides
important context for the forward looking information.




                                                                                            Aetna Inc.
                                                                                          2008 Guidance
                                                                                          as of 7/31/2008
                                                                                 (Full year unless otherwise noted)
                            Aetna Inc.
                                                                                          $4.00 per share
                                 Operating Earnings (1)
                                                                                      3Q 2008 $1.12 per share

                                                                                       ≈ 30 bps improvement
                                 Operating Expense Ratio (2)

                                 Pretax Operating Margin (3)                              Lower than 2007

                                                                                       Less than 495 million
                                 Weighted-Average Diluted Shares


                            Health Care Segment
                                                                                      Growth of 850k - 900k
                               Medical Membership

                                 Revenue (4)                                     Health care revenue growth of at
                                                                                            least 15%

                                 Commercial Medical Benefit Ratio (5)                    Less than 80%
                                                                                      3Q 2008 79.0%-79.5%

                                 Total Medical Benefit Ratio (5)                          Less than 81.5%

                                                                                  In line with medical cost trend
                                 Premium Yield

                                                                                          7.5% +/- 50 bps
                                 Medical Cost Trend


Note: The symbol “≈” means “approximately”.




July 31, 2008                                                      Aetna Inc.                                                         Page 1 of 2
Footnotes

(1) Projected full year 2008 operating earnings per share exclude net realized capital losses of $52.3 million after tax and the release of
reserves for anticipated future losses on discontinued products of $28.5 million after tax reported by Aetna in the six months ended June 30,
2008. Projected operating earnings per share also exclude any future net realized capital gains or losses and other items, if any, from net
income. Aetna is not able to project the amount of future net realized capital gains or losses and therefore cannot reconcile projected operating
earnings to projected net income or to a projected change in net income in any period. Although the excluded items may recur, management
believes that operating earnings and operating earnings per share provide a more useful comparison of Aetna’s underlying business
performance from period to period. Net realized capital gains and losses arise from various types of transactions, primarily in the course of
managing a portfolio of assets that support the payment of liabilities. However, these transactions do not directly relate to the underwriting or
servicing of products for customers and are not directly related to the core performance of Aetna’s business operations. The release of
reserves for anticipated future losses on discontinued products represents a reduction of reserves previously established for certain products no
longer offered by Aetna that does not benefit ongoing business operations. In addition, management uses operating earnings to assess business
performance and to make decisions regarding Aetna’s operations and allocation of resources among Aetna’s businesses.

(2) The operating expense ratio is calculated by dividing operating expenses by total revenue excluding net realized capital gains or losses.
Aetna cannot reconcile the projected operating expense ratio to a comparable GAAP measure, because it cannot project net realized capital
gains or losses.

(3) Pretax operating margin is calculated by dividing pretax operating earnings determined as described in note (1) above, excluding interest
expense and amortization of other acquired intangible assets by total revenue excluding net realized capital gains or losses. Aetna cannot
reconcile the projected pretax operating margin to a comparable GAAP measure, because it cannot project net realized capital gains or losses.

(4) Projected full year 2008 revenue in the Health Care segment excludes net realized capital losses (pre-tax) of $31.7 million reported by
Aetna for the six months ended June 30, 2008. Projected revenue also excludes any future net realized capital gains or losses (pre-tax), which
are included in reported GAAP revenue. Aetna cannot reconcile projected revenue to GAAP revenue, because it cannot project net realized
capital gains or losses.

(5) Commercial Medical Benefit Ratio includes all medical, dental, and other health care products except Medicare and Medicaid. Total
Medical Benefit Ratio includes all health care products.

CAUTIONARY STATEMENT; ADDITIONAL INFORMATION -- Certain information in this document is forward looking, including our
projections as to operating earnings per share, operating expense ratio, pretax operating margin, weighted-average diluted shares, medical
membership, health care revenue, commercial medical benefit ratio, total medical benefit ratio, premium yield and medical cost trend.
Forward-looking information is based on management's estimates, assumptions and projections, and is subject to significant uncertainties and
other factors, many of which are beyond Aetna's control. Important risk factors could cause actual future results and other future events to
differ materially from those currently estimated by management, including failure to achieve desired rate increases and/or profitable
membership growth due to the slowing economy and/or significant competition, especially in key geographic markets where membership is
concentrated; adverse changes in size, product mix or medical cost experience of membership; adverse pricing or funding actions by federal or
state government payors; and adverse changes in federal or state government policies or regulation (including legislative proposals that would
affect our business model and/or limit our ability to price for the risk we assume and/or reflect reasonable costs or profits in our pricing, and
other proposals, such as initiatives to eliminate or reduce ERISA pre-emption of state laws, that would increase potential litigation exposure or
mandate coverage of certain health benefits). Other important risk factors include, but are not limited to: unanticipated increases in medical
costs (including increased medical utilization, increased pharmacy costs, increases resulting from unfavorable changes in contracting or re-
contracting with providers, changes in membership mix to lower-premium or higher-cost products or membership-adverse selection; as well as
changes in medical cost estimates due to the necessary extensive judgment that is used in the medical cost estimation process, the considerable
variability inherent in such estimates, and the sensitivity of such estimates to changes in medical claims payment patterns and changes in
medical cost trends); the ability to reduce administrative expenses while maintaining targeted levels of service and operating performance; the
ability to improve relations with providers while taking actions to reduce medical costs and/or expand the services we offer; reduced levels of
investment income from low interest rates; the ability to successfully integrate our businesses (including acquired businesses) and implement
multiple strategic and operational initiatives simultaneously; our ability to integrate, simplify, and enhance our existing information
technology systems and platforms to keep pace with changing customer and regulatory needs; the outcome of various litigation and regulatory
matters, including litigation and ongoing reviews of business practices by various regulatory authorities (including the current industry-wide
investigation by the New York Attorney General into certain payment practices with respect to out-of-network providers); reputational issues
arising from data security breaches or other means; and increases in medical costs or Group Insurance claims resulting from any acts of
terrorism, epidemics or other extreme events. For more discussion of important risk factors that may materially affect Aetna, please see the
risk factors contained in Aetna's 2007 Annual Report on Form 10-K, on file with the Securities and Exchange Commission (“SEC”). You also
should read Aetna's Quarterly Report on Form 10-Q for the quarter ended June 30, 2008 when filed with the SEC for a discussion of Aetna's
historical results of operations and financial condition.

                                                                      ###


July 31, 2008                                                        Aetna Inc.                                                           Page 2 of 2

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aetna Guidance Summary 2008 2nd

  • 1. The following is a summary of certain 2008 projected financial information and metrics provided by Aetna on July 31, 2008. This information is provided for reference only, and has not been updated. You should consider the information to speak only as of its date of original publication. Aetna does not assume any responsibility to update the information to reflect subsequent events. Please also refer to the Cautionary Statement; Additional Information below for additional information regarding important risk factors that may affect the forward looking and other information in this document. You should read this information in conjunction with Aetna’s earnings press release issued July 31, 2008 and should review the replay of the related investor call in full, since the press release provides further discussion of Aetna’s results, and the investor call provides important context for the forward looking information. Aetna Inc. 2008 Guidance as of 7/31/2008 (Full year unless otherwise noted) Aetna Inc. $4.00 per share Operating Earnings (1) 3Q 2008 $1.12 per share ≈ 30 bps improvement Operating Expense Ratio (2) Pretax Operating Margin (3) Lower than 2007 Less than 495 million Weighted-Average Diluted Shares Health Care Segment Growth of 850k - 900k Medical Membership Revenue (4) Health care revenue growth of at least 15% Commercial Medical Benefit Ratio (5) Less than 80% 3Q 2008 79.0%-79.5% Total Medical Benefit Ratio (5) Less than 81.5% In line with medical cost trend Premium Yield 7.5% +/- 50 bps Medical Cost Trend Note: The symbol “≈” means “approximately”. July 31, 2008 Aetna Inc. Page 1 of 2
  • 2. Footnotes (1) Projected full year 2008 operating earnings per share exclude net realized capital losses of $52.3 million after tax and the release of reserves for anticipated future losses on discontinued products of $28.5 million after tax reported by Aetna in the six months ended June 30, 2008. Projected operating earnings per share also exclude any future net realized capital gains or losses and other items, if any, from net income. Aetna is not able to project the amount of future net realized capital gains or losses and therefore cannot reconcile projected operating earnings to projected net income or to a projected change in net income in any period. Although the excluded items may recur, management believes that operating earnings and operating earnings per share provide a more useful comparison of Aetna’s underlying business performance from period to period. Net realized capital gains and losses arise from various types of transactions, primarily in the course of managing a portfolio of assets that support the payment of liabilities. However, these transactions do not directly relate to the underwriting or servicing of products for customers and are not directly related to the core performance of Aetna’s business operations. The release of reserves for anticipated future losses on discontinued products represents a reduction of reserves previously established for certain products no longer offered by Aetna that does not benefit ongoing business operations. In addition, management uses operating earnings to assess business performance and to make decisions regarding Aetna’s operations and allocation of resources among Aetna’s businesses. (2) The operating expense ratio is calculated by dividing operating expenses by total revenue excluding net realized capital gains or losses. Aetna cannot reconcile the projected operating expense ratio to a comparable GAAP measure, because it cannot project net realized capital gains or losses. (3) Pretax operating margin is calculated by dividing pretax operating earnings determined as described in note (1) above, excluding interest expense and amortization of other acquired intangible assets by total revenue excluding net realized capital gains or losses. Aetna cannot reconcile the projected pretax operating margin to a comparable GAAP measure, because it cannot project net realized capital gains or losses. (4) Projected full year 2008 revenue in the Health Care segment excludes net realized capital losses (pre-tax) of $31.7 million reported by Aetna for the six months ended June 30, 2008. Projected revenue also excludes any future net realized capital gains or losses (pre-tax), which are included in reported GAAP revenue. Aetna cannot reconcile projected revenue to GAAP revenue, because it cannot project net realized capital gains or losses. (5) Commercial Medical Benefit Ratio includes all medical, dental, and other health care products except Medicare and Medicaid. Total Medical Benefit Ratio includes all health care products. CAUTIONARY STATEMENT; ADDITIONAL INFORMATION -- Certain information in this document is forward looking, including our projections as to operating earnings per share, operating expense ratio, pretax operating margin, weighted-average diluted shares, medical membership, health care revenue, commercial medical benefit ratio, total medical benefit ratio, premium yield and medical cost trend. Forward-looking information is based on management's estimates, assumptions and projections, and is subject to significant uncertainties and other factors, many of which are beyond Aetna's control. Important risk factors could cause actual future results and other future events to differ materially from those currently estimated by management, including failure to achieve desired rate increases and/or profitable membership growth due to the slowing economy and/or significant competition, especially in key geographic markets where membership is concentrated; adverse changes in size, product mix or medical cost experience of membership; adverse pricing or funding actions by federal or state government payors; and adverse changes in federal or state government policies or regulation (including legislative proposals that would affect our business model and/or limit our ability to price for the risk we assume and/or reflect reasonable costs or profits in our pricing, and other proposals, such as initiatives to eliminate or reduce ERISA pre-emption of state laws, that would increase potential litigation exposure or mandate coverage of certain health benefits). Other important risk factors include, but are not limited to: unanticipated increases in medical costs (including increased medical utilization, increased pharmacy costs, increases resulting from unfavorable changes in contracting or re- contracting with providers, changes in membership mix to lower-premium or higher-cost products or membership-adverse selection; as well as changes in medical cost estimates due to the necessary extensive judgment that is used in the medical cost estimation process, the considerable variability inherent in such estimates, and the sensitivity of such estimates to changes in medical claims payment patterns and changes in medical cost trends); the ability to reduce administrative expenses while maintaining targeted levels of service and operating performance; the ability to improve relations with providers while taking actions to reduce medical costs and/or expand the services we offer; reduced levels of investment income from low interest rates; the ability to successfully integrate our businesses (including acquired businesses) and implement multiple strategic and operational initiatives simultaneously; our ability to integrate, simplify, and enhance our existing information technology systems and platforms to keep pace with changing customer and regulatory needs; the outcome of various litigation and regulatory matters, including litigation and ongoing reviews of business practices by various regulatory authorities (including the current industry-wide investigation by the New York Attorney General into certain payment practices with respect to out-of-network providers); reputational issues arising from data security breaches or other means; and increases in medical costs or Group Insurance claims resulting from any acts of terrorism, epidemics or other extreme events. For more discussion of important risk factors that may materially affect Aetna, please see the risk factors contained in Aetna's 2007 Annual Report on Form 10-K, on file with the Securities and Exchange Commission (“SEC”). You also should read Aetna's Quarterly Report on Form 10-Q for the quarter ended June 30, 2008 when filed with the SEC for a discussion of Aetna's historical results of operations and financial condition. ### July 31, 2008 Aetna Inc. Page 2 of 2