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BRISTOL-MYERS SQUIBB CONTINUES STRONG FINANCIAL PERFORMANCE
                LED BY DOUBLE-DIGIT GLOBAL SALES GROWTH

       •   Reports Broad-Based Net Sales Growth of 16% from Continuing Operations

       •   Records Pre-Tax Earnings from Continuing Operations of $1,221 Million representing
           an Increase of 24% from Second Quarter 2007

       •   Posts Second Quarter 2008 GAAP EPS from Continuing Operations of $0.36
           Compared to $0.30 in 2007, an Increase of 20%, and Non-GAAP EPS Growth from
           Continuing Operations of $0.43 Compared to $0.31 in 2007, an Increase of 39%

       •   Reaffirms 2008 EPS Guidance and 2007-2010 Expected 15% Non-GAAP EPS CAGR

       •   Plans Additional $1 Billion in Productivity Savings by 2012

       •   Submits Regulatory Filings for ONGLYZA (saxagliptin) in U.S. and Europe
       (NEW YORK, July 24, 2008) – Bristol-Myers Squibb Company (NYSE:BMY) today reported
very strong sales and earnings growth for the second quarter 2008 and announced additional plans to
proactively manage costs.
       “We are making measurable strides against the strategy we outlined for investors last year. In
addition to strong sales growth, we are making acquisitions, entering licensing agreements and investing
in our pipeline, as we deliver on our commitments to patients and investors,” said James M. Cornelius,
chairman and chief executive officer, Bristol-Myers Squibb. “We are also taking steps now to manage
through future exclusivity losses. Our improvement initiatives are enabling us to better manage our
costs and work more efficiently.
       “We are selecting the best of biotech and the best of the pharmaceutical industry and combining
these traits into a model which will position us as a next-generation BioPharma leader. As our second
quarter 2008 results indicate, we’re on the right path to help patients prevail over serious disease both
today, and in the future.”
                                              Second Quarter 2008
                                                              2008           2007            Change
       Net Sales                                              $5,203         $4,471          16%
       Net Earnings From Continuing Operations                $ 722          $ 588           23%
       GAAP Diluted EPS From Continuing Operations              0.36           0.30          20%
       Non-GAAP Diluted EPS From Continuing Operations          0.43           0.31          39%
       ($ amounts in millions, except per share amounts)


                                                     1
EXPANSION OF PRODUCTIVITY – ADDITIONAL $1 BILLION BY 2012
       In December 2007, the company announced a $1.5 billion productivity transformation initiative
(PTI) to be completed by 2010. The company is well on track to achieve this goal as underlined by its
current margin performance. At the time this initiative was announced, the company indicated this was
the first step to achieve a culture focused on continuous improvement.
       “As part of the plan to maximize our growth opportunities through 2011 and improve our
earnings base in 2012-2013, we have initiated an expansion of our productivity initiatives which will
result in an additional $1 billion of cost savings by 2012,” said Jean-Marc Huet, senior vice president
and chief financial officer. “We have commissioned several internal teams to execute against some
already identified projects. We will provide additional information on this second wave of productivity
initiatives and its costs by year-end.
       “While managing our cost base is critical, it is only one part of our strategy as we transition to a
next-generation BioPharma company. We continue to invest to improve the growth of our marketed
products and strengthen our pipeline. We are confident that we can deliver on our commitments and
improve our base business in 2012-2013.”


SECOND QUARTER RESULTS
•   Bristol-Myers Squibb posted second quarter 2008 net sales from continuing operations of $5.2
    billion, an increase of 16%, including a 5% favorable foreign exchange impact, compared to the
    same period in 2007. Pharmaceutical net sales totaled $4.5 billion and sales of Nutritionals totaled
    $728 million in the second quarter of 2008, representing increases of 16% and 17%, respectively,
    compared to 2007.


•   U.S. pharmaceutical net sales increased 17% to $2.6 billion in the second quarter of 2008 compared
    to the same period in 2007, primarily due to increased sales of PLAVIX®, the continued growth of
    ABILIFY® , strong results from the HIV and hepatitis portfolio and increasing contribution of recent
    launches of products such as ORENCIA®and IXEMPRA™.


•   International pharmaceutical net sales increased 15%, including a 12% favorable foreign exchange
    impact, to $1.9 billion in the second quarter of 2008 compared to the same period in 2007. The
    increase was primarily due to higher sales of BARACLUDE® and increased contributions from
    ABILIFY®, SPRYCEL™ and the HIV portfolio. The company’s reported international net sales do


                                                     2
not include copromotion sales reported by its alliance partner, sanofi-aventis, for PLAVIX® and
    AVAPRO®/AVALIDE®, which continue to show growth in the second quarter of 2008.


•   Cost of products sold, as a percentage of net sales, increased to 32.1% in the second quarter of 2008
    compared to 31.5% in the same period in 2007. This increase of 0.6% was driven by higher
    manufacturing rationalization charges in 2008 related to the implementation of the PTI which
    accounted for a 0.8% increase, partially offset by manufacturing cost improvements from previously
    implemented initiatives.

•   Marketing, selling and administrative expenses increased by 6%, including an unfavorable 5%
    foreign exchange impact, to $1,165 million in the second quarter of 2008 compared to the same
    period in 2007, primarily due to implementation costs associated with the PTI.

•   Advertising and product promotion spending increased by 19%, including an unfavorable 5%
    foreign exchange impact, to $420 million in the second quarter of 2008 compared to the same period
    in 2007, primarily due to increased investment in ABILIFY® and ORENCIA®.

•   Research and development expenses increased 9%, including an unfavorable 2% foreign exchange
    impact, to $826 million in the second quarter of 2008 from $755 million in the same period in 2007.
    The increase primarily reflects higher development spending for pipeline compounds as well as
    higher upfront and milestone payments in 2008.

•   Acquired in-process research and development charge of $32 million in the second quarter of 2008
    relates to the acquisition of Kosan Biosciences, Inc.

•   The company recorded earnings from continuing operations before minority interest and income
    taxes of $1,221 million in the second quarter of 2008, an increase of 24% compared to $985 million
    in the same period in 2007. The increase was driven by strong product performance in the
    pharmaceutical business as well as cost containment and productivity initiatives.


•   The effective tax rate on earnings from continuing operations before minority interest and income
    taxes was 21.1% for the second quarter of 2008, compared with 20.6% in the second quarter of
    2007. The second quarter 2008 effective tax rate includes the favorable impact related to the
    resolution of a tax audit from prior years. The Company expects the full year 2008 non-GAAP


                                                     3
effective tax rate from continuing operations to be in line with the previously issued guidance of
    approximately 24%.


•   On a GAAP basis, the company reported second quarter 2008 net earnings from continuing
    operations of $722 million or $0.36 per diluted share, compared to net earnings from continuing
    operations of $588 million or $0.30 per diluted share for the same period in 2007. This represents
    growth of 23% for net earnings and 20% for EPS from continuing operations. The 2008 operating
    results include charges of $109 million associated with the implementation of the previously
    announced PTI as well as a favorable resolution of a tax audit from prior years. On a non-GAAP
    basis excluding specified items, second quarter 2008 net earnings from continuing operations were
    $861 million, or $0.43 per diluted share, compared to $608 million, or $0.31 per diluted share for the
    same period in 2007. This represents non-GAAP growth of 42% for net earnings and 39% for EPS
    from continuing operations.


•   The company continues to focus on being efficient with its use of cash. Cash flow from operations
    totaled $1.1 billion in the second quarter of 2008. Also, net debt decreased by $386 million between
    the end of the first quarter and end of the second quarter of 2008.




                                                     4
PIPELINE AND BUSINESS DEVELOPMENTS
       Bristol-Myers Squibb and its partner AstraZeneca announced on July 23 that the regulatory
submissions for ONGLYZA (saxagliptin) were made in both the United States and in Europe on June 30
and July 1, respectively. The concurrent European filing further demonstrates the company’s
commitment to rapidly bring forward new medicines for serious unmet medical needs like type II
diabetes.
       Bristol-Myers Squibb is focusing on supplementing its internal research and development
portfolio with strategic partnerships and acquisitions. In May, the company entered into an agreement
with KAI Pharmaceuticals to develop and commercialize KAI’s novel acute heart attack medicine, KAI-
9803. In June, Bristol-Myers Squibb completed the acquisition of Kosan Biosciences, Inc., a cancer
therapeutics company with a library of novel compounds including Hsp90 inhibitors for cancer and
microtubule stabilizers, which may have additional potential in neurodegenerative diseases.


       The following regulatory and data milestones occurred in the second quarter:


       In July, approval of ERBITUX® in Japan for treatment of metastatic colorectal cancer.
   •
   •   At the annual meeting of the American Society of Clinical Oncology (ASCO), a landmark phase
       III study (FLEX) showed that the addition of ERBITUX®to platinum-based chemotherapy
       significantly increased overall survival in the first-line treatment of patients with advanced non-
       small cell lung cancer, when compared to platinum-based chemotherapy alone.
       In the United States, approval for new ABILIFY®indications for pediatric bipolar maintenance
   •
       therapy, pediatric schizophrenia maintenance therapy, and as add-on treatment to lithium or
       valproate for acute treatment of bipolar disorder.
       In Europe, approval for a 300 mg tablet of PLAVIX®.
   •
       Also in Europe, approval of an expanded indication for REYATAZ® 300 mg once-daily boosted
   •
       with ritonavir 100 mg as part of combination therapy in treatment-naïve HIV-1 infected patients.
   •   New Phase II data presented at the European League Against Rheumatism (EULAR)
       demonstrated that ORENCIA®may delay the development of rheumatoid arthritis in people with
       undifferentiated inflammatory arthritis.
       In April, ORENCIA® was approved by the FDA for treatment of juvenile rheumatoid arthritis.
   •

       Additionally, the U.S. label for ORENCIA® was revised with an indication that means


                                                    5
ORENCIA® is an appropriate option for patients with moderate-to-severe rheumatoid arthritis,
       regardless of prior treatment received.
   •   At the annual scientific sessions of the American Diabetes Association, a phase III study
       demonstrated that saxagliptin produced significant reductions in key measures of glucose control
       in treatment-naïve people with type 2 diabetes compared to placebo.


DISCONTINUED OPERATIONS
       The company agreed to sell the ConvaTec business for approximately $4.1 billion, subject to
customary post closing adjustments, to Avista Capital Partners L.P. and Nordic Capital Fund VII in
April 2008. The company expects to close the divestiture agreement by August 2008. The results of the
ConvaTec business are included in income from discontinued operations, net of tax, for all periods
presented.


2008 GUIDANCE
       Bristol-Myers Squibb reaffirms its 2008 earnings guidance for fully diluted earnings per share
from continuing operations on a GAAP basis to be between $1.36 and $1.46. The company also
reaffirms its 2008 fully diluted earnings per share from continuing operations guidance on a non-GAAP
basis to be between $1.60 and $1.70. The non-GAAP guidance excludes specified items as discussed
under “Use of Non-GAAP Financial Information.” Details reconciling adjusted non-GAAP amounts
with the amounts reflecting specified items are provided in supplemental materials available on the
company’s website.
       The company reaffirms guidance that it expects non-GAAP earnings per share from continuing
operations to grow at a minimum of 15 percent compounded annual growth rate, from the 2007 base
through 2010 without rebasing for the agreement to sell the ConvaTec business, excluding costs
associated with the Productivity Transformation Initiative and other specified items that have not yet
been identified and quantified.
       The 2008 guidance and the three-year compound annual growth rate exclude other specified
items such as gains or losses from sale of businesses and product lines; from sale of equity investments
and from discontinuations of operations; restructuring and other exit costs; accelerated depreciation
charges; asset impairments; charges and recoveries relating to significant legal proceedings; upfront and
milestone payments for licensing arrangements; payments for in-process research and development; debt
retirement costs; impairments to investments; and significant tax events.



                                                     6
The financial guidance for 2008 and the three-year compound annual growth rate exclude the
impact of any potential strategic acquisitions and divestitures and further assume that the company and
its product partner, sanofi-aventis, maintain U.S. exclusivity for the PLAVIX® patent through at least
2010.


Use of Non-GAAP Financial Information

        This press release contains non-GAAP financial measures, including non-GAAP earnings and
earnings per share information, adjusted to exclude certain costs, expenses, gains and losses and other
specified items. Among the items in GAAP measures but excluded for purposes of determining adjusted
earnings and other adjusted measures are: charges related to implementation of the Productivity
Transformation Initiative and the company’s strategy for Mead Johnson Nutritionals; gains or losses
from sale and leaseback of properties and from discontinuations of operations; restructuring and other
exit costs; accelerated depreciation charges; asset impairments; charges relating to significant legal
proceedings; upfront and milestone payments for in-licensing of products that have not achieved
regulatory approval that are immediately expensed; payments for in-process research and development;
impairments to investments; and significant tax events. This information is intended to enhance an
investor’s overall understanding of the company’s past financial performance and prospects for the
future. For example, non-GAAP earnings and earnings per share information is an indication of the
company’s baseline performance before items that are considered by the company to be not reflective of
the company’s ongoing results. In addition, this information is among the primary indicators the
company uses as a basis for evaluating company performance, allocating resources, setting incentive
compensation targets, and planning and forecasting of future periods. This information is not intended
to be considered in isolation or as a substitute for net earnings or diluted earnings per share prepared in
accordance with GAAP.

Statement on Cautionary Factors

        This press release contains certain forward-looking statements within the meaning of the Private
Securities Litigation Reform Act of 1995 regarding, among other things, statements relating to goals,
plans and projections regarding the company’s financial position, results of operations, market position,
product development and business strategy. These statements may be identified by the fact that they use
words such as quot;anticipatequot;, quot;estimatesquot;, quot;shouldquot;, quot;expectquot;, quot;guidancequot;, quot;projectquot;, quot;intendquot;, quot;planquot;,
quot;believequot; and other words and terms of similar meaning in connection with any discussion of future
operating or financial performance. Such forward-looking statements are based on current expectations
and involve inherent risks and uncertainties, including factors that could delay, divert or change any of
them, and could cause actual outcomes and results to differ materially from current expectations. These
factors include, among other things, market factors (including whether uncertainties in the credit and
capital markets or a further deterioration of these markets will lead to future impairments to the
company’s investment portfolio), competitive product development and approvals, pricing controls and
pressures (including changes in rules and practices of managed care groups and institutional and
governmental purchasers), economic conditions such as interest rate and currency exchange rate
fluctuations, judicial decisions and governmental laws and regulations related to Medicare, Medicaid
and healthcare reform, pharmaceutical rebates and reimbursement, claims and concerns that may arise
regarding the safety and efficacy of in-line products and product candidates, changes to wholesaler
inventory levels, variability in data provided by third parties, changes in, and interpretation of,

                                                    7
governmental regulations and legislation affecting domestic or foreign operations, including tax
obligations, difficulties and delays in product development, manufacturing or sales, patent positions and
the ultimate outcome of any litigation matter, including whether Apotex will prevail in its appeal of the
District court’s decision in the PLAVIX® patent litigation. These factors also include the company’s
ability to execute successfully its strategic plans, including its productivity transformation initiatives, the
expiration of patents or data protection on certain products (including the recent expiration of data
protection for PLAVIX® in the European Union), and the impact and result of governmental
investigations. There can be no guarantees with respect to pipeline products that future clinical studies
will support the data described in this release, that the products will receive necessary regulatory
approvals, or that they will prove to be commercially successful; nor are there guarantees that regulatory
approvals will be sought, or sought within currently expected timeframes, or that contractual milestones
will be achieved. For further details and a discussion of these and other risks and uncertainties, see the
company's periodic reports, including the annual report on Form 10-K, quarterly reports on Form 10-Q
and current reports on Form 8-K, filed with or furnished to the Securities and Exchange Commission.
The company undertakes no obligation to publicly update any forward-looking statement, whether as a
result of new information, future events or otherwise.

Company and Conference Call Information

        Bristol-Myers Squibb is a global pharmaceutical and related health care products company
whose mission is to extend and enhance human life.
        There will be a conference call on July 24, 2008 at 10:30 a.m. (EDT) during which company
executives will address inquiries from investors and analysts. Investors and the general public are
invited to listen to a live web cast of the call at www.bms.com/ir or by dialing 913-312-0976,
confirmation code 2526349. Materials related to the call will be available at the same website prior to
the call.
        For more information, contact: Brian Henry, 609-252-3337, Communications, Tracy Furey, 609-
252-3208, Communications, John Elicker, 212-546-3775, Investor Relations, or Suketu Desai, 609-252-
5796, Investor Relations.

ABILIFY® is the trademark of Otsuka Pharmaceutical Co., Ltd.
ATRIPLA™ is a trademark of both Bristol-Myers Squibb Co. and Gilead Sciences, Inc.
AVAPRO®, AVALIDE® and PLAVIX® are trademarks of sanofi-aventis
ERBITUX® is a trademark of ImClone Systems Incorporated




                                                       8
BRISTOL-MYERS SQUIBB COMPANY
                             NET SALES BY OPERATING SEGMENTS
                  FOR THE THREE AND SIX MONTHS ENDED JUNE 30, 2008 AND 2007
                                  (Unaudited, dollars in millions)



                                                    Three Months                  Six Months
                                                   Ended June 30,               Ended June 30,
                                                2008            2007         2008            2007

Pharmaceuticals                             $       4,475   $    3,851   $     8,663     $    7,308

Nutritionals                                         728           620         1,431          1,226

Net Sales                                   $       5,203   $    4,471   $    10,094     $    8,534




                                                9
BRISTOL-MYERS SQUIBB COMPANY
                                            SELECTED PRODUCTS
                          FOR THE THREE AND SIX MONTHS ENDED JUNE 30, 2008 AND 2007
                                          (Unaudited, dollars in millions)

        The following table sets forth worldwide and U.S. reported net sales for selected products for the three and six
        months ended June 30, 2008 compared to the three and six months ended June 30, 2007. In addition, the table
        includes, where applicable, the estimated total U.S. prescription change for the retail and mail-order channels for the
        comparative periods presented for certain of the company's U.S. pharmaceutical products based on third-party data.
        A significant portion of the company's U.S. pharmaceutical sales is made to wholesalers. Where changes in reported
        net sales differ from prescription growth, this change in net sales may not reflect underlying prescriber demand.


                                          Worldwide Net Sales                   U.S. Net Sales
                                                            %                                  %       % Change in U.S. Total
                                        2008    2007     Change         2008        2007     Change    Prescriptions vs. 2007

Three Months Ended June 30,

Pharmaceuticals
Cardiovascular
   Plavix                              $ 1,387 $ 1,189    17%          $1,207     $ 1,015     19%               11%
   Avapro/Avalide                          335     297    13%             184         170      8%               (8)%
   Pravachol                                69     132   (48)%             10          47    (79)%             (83)%
Virology
   Reyataz                                324     254     28%            159          138        15%            13%
   Sustiva Franchise (total revenue)      282     233     21%            171          147        16%            13%
   Baraclude                              136      59    131%             35           20        75%            60%
Oncology
   Erbitux                                196     162      21%           193          160       21%             N/A
   Taxol                                  101      95       6%             3            4    (25)%              N/A
   Sprycel                                 76      35    117%             21           14      50%              44%
   Ixempra                                 26      ---      ---           26           ---       ---            N/A
Affective (Psychiatric) Disorders
   Abilify (total revenue)                529     412     28%            403          322        25%            19%
Immunoscience
   Orencia                                106      55     93%             87           53        64%            N/A
Nutritionals
   Enfamil                               287      267      7%            175          177     (1)%              N/A




                                                                  10
(Continued)

                                         Worldwide Net Sales       U.S. Net Sales
                                                          %                            %        % Change in U.S. Total
                                       2008    2007     Change     2008     2007     Change     Prescriptions vs. 2007

Six Months Ended June 30,

Pharmaceuticals
Cardiovascular
                                                          27%
   Plavix                              $2,695   $2,127             $2,346   $1,802      30%                37%
   Avapro/Avalide                         640      567     13%        358      333       8%               (7)%
   Pravachol                              142      267   (47)%         25      104    (76)%              (82)%
Virology
   Reyataz                               621      517     20%        319      281      14%                12%
   Sustiva Franchise (total revenue)     555      459     21%        346      291      19%                14%
   Baraclude                             244      104    135%         64       37      73%                60%
Oncology
   Erbitux                               383      322     19%        378      318       19%               N/A
   Taxol                                 195      206     (5)%         3        8     (63)%               N/A
   Sprycel                               142       56    154%         41       24       71%               50%
                                                                               ---
   Ixempra                                51       ---       ---      51                  ---             N/A
Affective (Psychiatric) Disorders
   Abilify (total revenue)               983      778     26%        751      615      22%                17%
Immunoscience
   Orencia                               193       96    101%        160       93      72%                N/A
Nutritionals
   Enfamil                               577      521     11%        358      348        3%               N/A




                                                              11
BRISTOL-MYERS SQUIBB COMPANY
                               CONSOLIDATED STATEMENTS OF EARNINGS
                       FOR THE THREE AND SIX MONTHS ENDED JUNE 30, 2008 AND 2007
                              (Unaudited, amounts in millions except per share data)

                                                                  Three Months               Six Months
                                                                 Ended June 30,            Ended June 30,
                                                               2008          2007        2008          2007


Net Sales                                                 $ 5,203        $ 4,471     $10,094       $ 8,534
Cost of products sold                                       1,670          1,408       3,240         2,674
Marketing, selling and administrative                       1,165          1,103       2,299         2,155
Advertising and product promotion                             420            354         739           612
Research and development                                      826            755       1,608         1,536
Acquired in-process research and development                   32             —           32            —
Provision for restructuring, net                               30              7          41            44
Litigation expense, net                                         2             14           2            14
Gain on sale of product assets                                 —             (26)         —            (26)
Equity in net income of affiliates                           (150)          (128)       (314)         (254)
Other (income)/expense, net (a)                               (13)            (1)         19            21
Total expenses                                              3,982          3,486       7,666         6,776
Earnings from Continuing Operations
                                                              1,221           985        2,428         1,758
Before Minority Interest and Income Taxes
Provision for income taxes                                      258           203          588           243
Minority interest, net of taxes                                 241           194          471           335
Net Earnings from Continuing Operations                        722            588        1,369         1,180

Discontinued Operations:
Earnings, net of taxes                                          42            118         99           216
Loss on Disposal, net of taxes                                  —              —         (43)           —
                                                                42            118         56           216
Net Earnings                                              $    764       $    706    $ 1,425       $ 1,396
Earnings per Common Share
Basic:
   Net Earnings from Continuing Operations                $ 0.37         $ 0.30      $ 0.69        $ 0.60
   Discontinued Operations:
     Earnings, net of taxes                                 0.02           0.06         0.05         0.11
     Loss on Disposal, net of taxes                           —             —          (0.02)         —
   Net Earnings per Common Share                          $ 0.39         $ 0.36      $ 0.72        $ 0.71
Diluted:
   Net Earnings from Continuing Operations                $ 0.36         $ 0.30      $ 0.69        $ 0.60
   Discontinued Operations:
     Earnings, net of taxes                                 0.02           0.06         0.05         0.11
     Loss on Disposal , net of taxes                          —              —         (0.02)         —
   Net Earnings per Common Share                          $ 0.38         $ 0.36      $ 0.72        $ 0.71

Average Common Shares Outstanding:
Basic                                                         1,977          1,968       1,976         1,965
Diluted                                                       2,008          2,006       2,007         2,002
(a)
      Other (income)/expense, net
       Interest expense                                   $      80      $    107    $    153      $  216
       Interest income                                          (31)          (62)        (74)       (115)
       Foreign exchange transaction losses                       (2)           (5)         17           3
       Other expense, net                                       (60)          (41)        (77)        (83)
                                                          $     (13)     $     (1)   $     19      $   21


                                                    12
BRISTOL-MYERS SQUIBB COMPANY
                                               SPECIFIED ITEMS
                              FOR THE THREE MONTHS ENDED JUNE 30, 2008 AND 2007
                                           (Unaudited, dollars in millions)

Three months ended June 30, 2008

                                                                                                                               Other
                                           Cost of      Marketing,            Research                                       (income)/
                                                                                            Provision for Litigation expense expense,
                                          products      selling and             and
                                                                                          restructuring, net       net          net          Total
                                            sold       administrative       development
Productivity Transformation
Initiative:
Downsizing and streamlining of
                                              -             -                    -        $    30            $       -        $     -    $ 30
 worldwide operations                   $              $                   $
Accelerated depreciation and other
                                            58              -                    -                 -                 -              -          58
 shutdown costs
Process standardization
                                             -             21                    -              -                    -              -          21
 implementation costs
                                                                                 -             30
                                            58             21                                                        -              -         109

Litigation Matters:
Litigation settlement                         -                -                 -             -                     2              -            2

Other:
Mead Johnson Nutritionals charges             -             1                   -                  -                 -              -           1
Upfront and milestone payments                -             -                  31                  -                 -              -          31
Acquired in-process research &
 development                               -              -                  32                 -                   -            -             32
Auction rate securities impairment         -              -                   -                 -                   -           (2)            (2)
                                        $ 58           $ 22                $ 63           $    30            $      2         $ (2)           173
Income taxes on items above                                                                                                                (34)
(Increase)/Decrease to Net Earnings from Continuing Operations                                                                           $ 139

Three months ended June 30, 2007

                                                                                                                            Gain
                                                            Cost of                       Provision for     Litigation    on sale of
                                                           products        Research and   restructuring,    expense,       product
                                                             sold                               net             net
                                                                           development                                      assets           Total
 Litigation Matters:
 Litigation settlement                                     $          -    $         -    $            -    $      14     $         -    $           14

 Other:
 Accelerated depreciation                                          13             -                    -            -                -           13
 Upfront and milestone payments                                     -            17                    -            -                -           17
 Downsizing and streamlining of worldwide operations                -             -                    7            -                -            7
 Gain on sale of product asset                                      -             -                    -            -             (26)          (26)
                                                         $         13      $     17        $           7    $      14     $       (26)           25
 Income taxes on items above                                                                                                                     (5)
 (Increase)/Decrease to Net Earnings from Continuing Operations                                                                          $       20




                                                                      13
BRISTOL-MYERS SQUIBB COMPANY
                                                     SPECIFIED ITEMS
                                     FOR THE SIX MONTHS ENDED JUNE 30, 2008 AND 2007
                                                 (Unaudited, dollars in millions)
Six months ended June 30, 2008
                                                        Marketing,                                    Provision                                Other
                                                          selling                                         for                                (income)/
                                                                               Research                                     Litigation
                                      Cost of products     and                   and                restructuring,           expense,         expense,
                                            sold       administrative        development                  net                   net             net           Total
Productivity Transformation
Initiative:
Downsizing and streamlining of
                                                 -              -                  -                                            -
                                                                                                    $ 41                                     $      -        $ 41
 worldwide operations                   $                  $                 $                                          $
Accelerated depreciation and other
                                            154                 -                  -                     -                      -                   -         154
 shutdown costs
Process standardization
                                                 -             36                  -                     -                      -                   -          36
 implementation costs
Gain on sale and leaseback of
                                              -                 -                  -                    -                       -                  (9)         (9)
 properties
                                                                                   -                                            -
                                            154                36                                      41                                          (9)        222

Litigation Matters:
Litigation settlement                            -              -                  -                     -                     2                    -            2

Other:
Mead Johnson Nutritionals charges                -             1                   -                     -                      -                   -           1
Product liability                                -             -                   -                     -                      -                  16          16
Upfront and milestone payments                   -             -                  51                     -                      -                   -          51
Acquired in-process research &
 development                                -                 -                32                      -                       -                -              32
Auction rate securities impairment          -                 -                 -                      -                       -               23              23
                                        $ 154              $ 37              $ 83                   $ 41                $      2             $ 30             347
Income taxes on items above                                                                                                                                   (67)
(Increase)/Decrease to Net Earnings from Continuing Operations                                                                                                280

Six months ended June 30, 2007
                                                                                                                                         Gain on
                                                                                                                                         sale of
                                                 Cost of         Research          Provision for
                                                products           and             restructuring,             Litigation                 product
                                                                                                             expense, net
                                                  sold         development               net                                              assets             Total
Litigation Matters:
Litigation settlement                       $         -        $     -            $       -              $            14            $        -           $    14

Other:
Upfront and milestone payments                        -             97                    -                             -                    -                 97
Downsizing and streamlining of
                                                      -              -                  44                             -                     -              44
 worldwide operations
Accelerated depreciation                             29              -                   -                             -                     -              29
Gain on sale of product asset                         -              -                   -                             -                   (26)            (26)
                                          $          29
                                                      $             97            $     44               $            14            $      (26)            158
Income taxes on items above                                                                                                                                (45)
Change in estimate for taxes on prior year items                                                                                                           (39)
(Increase)/Decrease to Net Earnings from Continuing Operations                                                                                           $ 74




                                                                             14
BRISTOL-MYERS SQUIBB COMPANY
                                         RECONCILIATION OF GAAP RESULTS OF CONTINUING OPERATIONS
                                              TO NON-GAAP RESULTS OF CONTINUING OPERATIONS
                                             FOR THE THREE MONTHS ENDED JUNE 30, 2008 AND 2007
                                                            (Unaudited, amounts in millions except per share data)

                                                                                          Q2 2007                                 Q2 2008
                                                                                          Specified                               Specified
                                                                                                            Non                                    Non
                                                                               GAAP                                      GAAP
                                                                                           Items*                                  Items*
                                                                                                           GAAP                                   GAAP


           Net Sales                                                       $ 4,471                                   $ 5,203
                                                                                                       $ 4,471                                $ 5,203
           Cost of Products Sold                                               1,408           (13)                      1,670       (58)
                                                                                                           1,395                                  1,612
               Gross Profit                                                    3,063            13                       3,533        58
                                                                                                           3,076                                  3,591
                                                                                               0.3%                                  1.1%
                    Gross Margin as% of Sales                                   68.5%                       68.8%         67.9%                    69.0%


           Marketing Selling and Admin                                         1,103                                     1,165       (22)
                                                                                                           1,103                                  1,143
           Advertising and Product Promotion                                    354                                       420
                                                                                                            354                                    420
               Total SGA                                                       1,457                                     1,585       (22)
                                                                                                           1,457                                  1,563
                                                                                                                                      (.5%)
                    SG&A as % of Sales                                          32.6%                       32.6%         30.5%                    30.0%


           R&D                                                                  755            (17)                       826        (31)
                                                                                                            738                                    795
                                                                                               (.4%)                                (0.6%)
                    R&D as % of Sales                                           16.9%                       16.5%         15.9%                    15.3%


           Acquired in-process research and development                                                                    32        (32)             -
           Provision for restructuring, net                                        7            (7)                        30        (30)
                                                                                                               -                                      -
           Litigation expense, net                                               14            (14)                          2         (2)
                                                                                                               -                                      -
           Gain on sale of Product Assets                                        (26)           26                           -
                                                                                                               -                                      -
           Equity in Net Income of Affiliates                                   (128)                                     (150)
                                                                                                            (128)                                  (150)
           Other (income)/expense, net                                            (1)                                      (13)         2
                                                                                                              (1)                                   (11)

           Earnings from Continuing Operations Before Minority
                                                                                985             25                       1,221       173
           Interest & Taxes                                                                                1,010                              $ 1,394


           Provision for income taxes                                           203              5                        258         34
                                                                                                            208                                    292
                    Effective Tax Rate                                          20.6%                       20.6%         21.1%       (.2%)        20.9%

           Minority Interest, net of taxes                                      194                                       241
                                                                                                            194                                    241

           Net Earnings - Continuing Operations                                 588             20                        722        139
                                                                                                            608                                    861
                  Net Earnings - Continuing Operations as a %
                                                                               13.2%          0.4%         13.6%         13.9%     2.6%           16.5%
                  of sales


               Net Earnings – Discontinued Ops                                  118                                        42
                                                                                                            118                                     42
           Net Earnings                                                    $    706             20                   $    764        139
                                                                                                       $    726                               $    903

              Interest Exp on Conv. Of Conv Debt Bonds                             9                           9             4                $       4
           Net Earnings used for Diluted EPS Calc - Continuing
           Operations.                                                     $    597             20     $    617           726        139      $    865


           Avg Shares (Diluted)                                                2,006                                     2,008
                                                                                                           2,006                                  2,008

           Diluted EPS - Continuing Operations                             $     0.30           .01                  $     0.36       .07
                                                                                                       $     0.31                             $     0.43


* Please refer to the Specified Items schedules on previous pages for further details.




                                                                                         15

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bristol myerd squibb Bristol-Myers Squibb Company Reports Second Quarter 2008 Financial Results

  • 1. BRISTOL-MYERS SQUIBB CONTINUES STRONG FINANCIAL PERFORMANCE LED BY DOUBLE-DIGIT GLOBAL SALES GROWTH • Reports Broad-Based Net Sales Growth of 16% from Continuing Operations • Records Pre-Tax Earnings from Continuing Operations of $1,221 Million representing an Increase of 24% from Second Quarter 2007 • Posts Second Quarter 2008 GAAP EPS from Continuing Operations of $0.36 Compared to $0.30 in 2007, an Increase of 20%, and Non-GAAP EPS Growth from Continuing Operations of $0.43 Compared to $0.31 in 2007, an Increase of 39% • Reaffirms 2008 EPS Guidance and 2007-2010 Expected 15% Non-GAAP EPS CAGR • Plans Additional $1 Billion in Productivity Savings by 2012 • Submits Regulatory Filings for ONGLYZA (saxagliptin) in U.S. and Europe (NEW YORK, July 24, 2008) – Bristol-Myers Squibb Company (NYSE:BMY) today reported very strong sales and earnings growth for the second quarter 2008 and announced additional plans to proactively manage costs. “We are making measurable strides against the strategy we outlined for investors last year. In addition to strong sales growth, we are making acquisitions, entering licensing agreements and investing in our pipeline, as we deliver on our commitments to patients and investors,” said James M. Cornelius, chairman and chief executive officer, Bristol-Myers Squibb. “We are also taking steps now to manage through future exclusivity losses. Our improvement initiatives are enabling us to better manage our costs and work more efficiently. “We are selecting the best of biotech and the best of the pharmaceutical industry and combining these traits into a model which will position us as a next-generation BioPharma leader. As our second quarter 2008 results indicate, we’re on the right path to help patients prevail over serious disease both today, and in the future.” Second Quarter 2008 2008 2007 Change Net Sales $5,203 $4,471 16% Net Earnings From Continuing Operations $ 722 $ 588 23% GAAP Diluted EPS From Continuing Operations 0.36 0.30 20% Non-GAAP Diluted EPS From Continuing Operations 0.43 0.31 39% ($ amounts in millions, except per share amounts) 1
  • 2. EXPANSION OF PRODUCTIVITY – ADDITIONAL $1 BILLION BY 2012 In December 2007, the company announced a $1.5 billion productivity transformation initiative (PTI) to be completed by 2010. The company is well on track to achieve this goal as underlined by its current margin performance. At the time this initiative was announced, the company indicated this was the first step to achieve a culture focused on continuous improvement. “As part of the plan to maximize our growth opportunities through 2011 and improve our earnings base in 2012-2013, we have initiated an expansion of our productivity initiatives which will result in an additional $1 billion of cost savings by 2012,” said Jean-Marc Huet, senior vice president and chief financial officer. “We have commissioned several internal teams to execute against some already identified projects. We will provide additional information on this second wave of productivity initiatives and its costs by year-end. “While managing our cost base is critical, it is only one part of our strategy as we transition to a next-generation BioPharma company. We continue to invest to improve the growth of our marketed products and strengthen our pipeline. We are confident that we can deliver on our commitments and improve our base business in 2012-2013.” SECOND QUARTER RESULTS • Bristol-Myers Squibb posted second quarter 2008 net sales from continuing operations of $5.2 billion, an increase of 16%, including a 5% favorable foreign exchange impact, compared to the same period in 2007. Pharmaceutical net sales totaled $4.5 billion and sales of Nutritionals totaled $728 million in the second quarter of 2008, representing increases of 16% and 17%, respectively, compared to 2007. • U.S. pharmaceutical net sales increased 17% to $2.6 billion in the second quarter of 2008 compared to the same period in 2007, primarily due to increased sales of PLAVIX®, the continued growth of ABILIFY® , strong results from the HIV and hepatitis portfolio and increasing contribution of recent launches of products such as ORENCIA®and IXEMPRA™. • International pharmaceutical net sales increased 15%, including a 12% favorable foreign exchange impact, to $1.9 billion in the second quarter of 2008 compared to the same period in 2007. The increase was primarily due to higher sales of BARACLUDE® and increased contributions from ABILIFY®, SPRYCEL™ and the HIV portfolio. The company’s reported international net sales do 2
  • 3. not include copromotion sales reported by its alliance partner, sanofi-aventis, for PLAVIX® and AVAPRO®/AVALIDE®, which continue to show growth in the second quarter of 2008. • Cost of products sold, as a percentage of net sales, increased to 32.1% in the second quarter of 2008 compared to 31.5% in the same period in 2007. This increase of 0.6% was driven by higher manufacturing rationalization charges in 2008 related to the implementation of the PTI which accounted for a 0.8% increase, partially offset by manufacturing cost improvements from previously implemented initiatives. • Marketing, selling and administrative expenses increased by 6%, including an unfavorable 5% foreign exchange impact, to $1,165 million in the second quarter of 2008 compared to the same period in 2007, primarily due to implementation costs associated with the PTI. • Advertising and product promotion spending increased by 19%, including an unfavorable 5% foreign exchange impact, to $420 million in the second quarter of 2008 compared to the same period in 2007, primarily due to increased investment in ABILIFY® and ORENCIA®. • Research and development expenses increased 9%, including an unfavorable 2% foreign exchange impact, to $826 million in the second quarter of 2008 from $755 million in the same period in 2007. The increase primarily reflects higher development spending for pipeline compounds as well as higher upfront and milestone payments in 2008. • Acquired in-process research and development charge of $32 million in the second quarter of 2008 relates to the acquisition of Kosan Biosciences, Inc. • The company recorded earnings from continuing operations before minority interest and income taxes of $1,221 million in the second quarter of 2008, an increase of 24% compared to $985 million in the same period in 2007. The increase was driven by strong product performance in the pharmaceutical business as well as cost containment and productivity initiatives. • The effective tax rate on earnings from continuing operations before minority interest and income taxes was 21.1% for the second quarter of 2008, compared with 20.6% in the second quarter of 2007. The second quarter 2008 effective tax rate includes the favorable impact related to the resolution of a tax audit from prior years. The Company expects the full year 2008 non-GAAP 3
  • 4. effective tax rate from continuing operations to be in line with the previously issued guidance of approximately 24%. • On a GAAP basis, the company reported second quarter 2008 net earnings from continuing operations of $722 million or $0.36 per diluted share, compared to net earnings from continuing operations of $588 million or $0.30 per diluted share for the same period in 2007. This represents growth of 23% for net earnings and 20% for EPS from continuing operations. The 2008 operating results include charges of $109 million associated with the implementation of the previously announced PTI as well as a favorable resolution of a tax audit from prior years. On a non-GAAP basis excluding specified items, second quarter 2008 net earnings from continuing operations were $861 million, or $0.43 per diluted share, compared to $608 million, or $0.31 per diluted share for the same period in 2007. This represents non-GAAP growth of 42% for net earnings and 39% for EPS from continuing operations. • The company continues to focus on being efficient with its use of cash. Cash flow from operations totaled $1.1 billion in the second quarter of 2008. Also, net debt decreased by $386 million between the end of the first quarter and end of the second quarter of 2008. 4
  • 5. PIPELINE AND BUSINESS DEVELOPMENTS Bristol-Myers Squibb and its partner AstraZeneca announced on July 23 that the regulatory submissions for ONGLYZA (saxagliptin) were made in both the United States and in Europe on June 30 and July 1, respectively. The concurrent European filing further demonstrates the company’s commitment to rapidly bring forward new medicines for serious unmet medical needs like type II diabetes. Bristol-Myers Squibb is focusing on supplementing its internal research and development portfolio with strategic partnerships and acquisitions. In May, the company entered into an agreement with KAI Pharmaceuticals to develop and commercialize KAI’s novel acute heart attack medicine, KAI- 9803. In June, Bristol-Myers Squibb completed the acquisition of Kosan Biosciences, Inc., a cancer therapeutics company with a library of novel compounds including Hsp90 inhibitors for cancer and microtubule stabilizers, which may have additional potential in neurodegenerative diseases. The following regulatory and data milestones occurred in the second quarter: In July, approval of ERBITUX® in Japan for treatment of metastatic colorectal cancer. • • At the annual meeting of the American Society of Clinical Oncology (ASCO), a landmark phase III study (FLEX) showed that the addition of ERBITUX®to platinum-based chemotherapy significantly increased overall survival in the first-line treatment of patients with advanced non- small cell lung cancer, when compared to platinum-based chemotherapy alone. In the United States, approval for new ABILIFY®indications for pediatric bipolar maintenance • therapy, pediatric schizophrenia maintenance therapy, and as add-on treatment to lithium or valproate for acute treatment of bipolar disorder. In Europe, approval for a 300 mg tablet of PLAVIX®. • Also in Europe, approval of an expanded indication for REYATAZ® 300 mg once-daily boosted • with ritonavir 100 mg as part of combination therapy in treatment-naïve HIV-1 infected patients. • New Phase II data presented at the European League Against Rheumatism (EULAR) demonstrated that ORENCIA®may delay the development of rheumatoid arthritis in people with undifferentiated inflammatory arthritis. In April, ORENCIA® was approved by the FDA for treatment of juvenile rheumatoid arthritis. • Additionally, the U.S. label for ORENCIA® was revised with an indication that means 5
  • 6. ORENCIA® is an appropriate option for patients with moderate-to-severe rheumatoid arthritis, regardless of prior treatment received. • At the annual scientific sessions of the American Diabetes Association, a phase III study demonstrated that saxagliptin produced significant reductions in key measures of glucose control in treatment-naïve people with type 2 diabetes compared to placebo. DISCONTINUED OPERATIONS The company agreed to sell the ConvaTec business for approximately $4.1 billion, subject to customary post closing adjustments, to Avista Capital Partners L.P. and Nordic Capital Fund VII in April 2008. The company expects to close the divestiture agreement by August 2008. The results of the ConvaTec business are included in income from discontinued operations, net of tax, for all periods presented. 2008 GUIDANCE Bristol-Myers Squibb reaffirms its 2008 earnings guidance for fully diluted earnings per share from continuing operations on a GAAP basis to be between $1.36 and $1.46. The company also reaffirms its 2008 fully diluted earnings per share from continuing operations guidance on a non-GAAP basis to be between $1.60 and $1.70. The non-GAAP guidance excludes specified items as discussed under “Use of Non-GAAP Financial Information.” Details reconciling adjusted non-GAAP amounts with the amounts reflecting specified items are provided in supplemental materials available on the company’s website. The company reaffirms guidance that it expects non-GAAP earnings per share from continuing operations to grow at a minimum of 15 percent compounded annual growth rate, from the 2007 base through 2010 without rebasing for the agreement to sell the ConvaTec business, excluding costs associated with the Productivity Transformation Initiative and other specified items that have not yet been identified and quantified. The 2008 guidance and the three-year compound annual growth rate exclude other specified items such as gains or losses from sale of businesses and product lines; from sale of equity investments and from discontinuations of operations; restructuring and other exit costs; accelerated depreciation charges; asset impairments; charges and recoveries relating to significant legal proceedings; upfront and milestone payments for licensing arrangements; payments for in-process research and development; debt retirement costs; impairments to investments; and significant tax events. 6
  • 7. The financial guidance for 2008 and the three-year compound annual growth rate exclude the impact of any potential strategic acquisitions and divestitures and further assume that the company and its product partner, sanofi-aventis, maintain U.S. exclusivity for the PLAVIX® patent through at least 2010. Use of Non-GAAP Financial Information This press release contains non-GAAP financial measures, including non-GAAP earnings and earnings per share information, adjusted to exclude certain costs, expenses, gains and losses and other specified items. Among the items in GAAP measures but excluded for purposes of determining adjusted earnings and other adjusted measures are: charges related to implementation of the Productivity Transformation Initiative and the company’s strategy for Mead Johnson Nutritionals; gains or losses from sale and leaseback of properties and from discontinuations of operations; restructuring and other exit costs; accelerated depreciation charges; asset impairments; charges relating to significant legal proceedings; upfront and milestone payments for in-licensing of products that have not achieved regulatory approval that are immediately expensed; payments for in-process research and development; impairments to investments; and significant tax events. This information is intended to enhance an investor’s overall understanding of the company’s past financial performance and prospects for the future. For example, non-GAAP earnings and earnings per share information is an indication of the company’s baseline performance before items that are considered by the company to be not reflective of the company’s ongoing results. In addition, this information is among the primary indicators the company uses as a basis for evaluating company performance, allocating resources, setting incentive compensation targets, and planning and forecasting of future periods. This information is not intended to be considered in isolation or as a substitute for net earnings or diluted earnings per share prepared in accordance with GAAP. Statement on Cautionary Factors This press release contains certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 regarding, among other things, statements relating to goals, plans and projections regarding the company’s financial position, results of operations, market position, product development and business strategy. These statements may be identified by the fact that they use words such as quot;anticipatequot;, quot;estimatesquot;, quot;shouldquot;, quot;expectquot;, quot;guidancequot;, quot;projectquot;, quot;intendquot;, quot;planquot;, quot;believequot; and other words and terms of similar meaning in connection with any discussion of future operating or financial performance. Such forward-looking statements are based on current expectations and involve inherent risks and uncertainties, including factors that could delay, divert or change any of them, and could cause actual outcomes and results to differ materially from current expectations. These factors include, among other things, market factors (including whether uncertainties in the credit and capital markets or a further deterioration of these markets will lead to future impairments to the company’s investment portfolio), competitive product development and approvals, pricing controls and pressures (including changes in rules and practices of managed care groups and institutional and governmental purchasers), economic conditions such as interest rate and currency exchange rate fluctuations, judicial decisions and governmental laws and regulations related to Medicare, Medicaid and healthcare reform, pharmaceutical rebates and reimbursement, claims and concerns that may arise regarding the safety and efficacy of in-line products and product candidates, changes to wholesaler inventory levels, variability in data provided by third parties, changes in, and interpretation of, 7
  • 8. governmental regulations and legislation affecting domestic or foreign operations, including tax obligations, difficulties and delays in product development, manufacturing or sales, patent positions and the ultimate outcome of any litigation matter, including whether Apotex will prevail in its appeal of the District court’s decision in the PLAVIX® patent litigation. These factors also include the company’s ability to execute successfully its strategic plans, including its productivity transformation initiatives, the expiration of patents or data protection on certain products (including the recent expiration of data protection for PLAVIX® in the European Union), and the impact and result of governmental investigations. There can be no guarantees with respect to pipeline products that future clinical studies will support the data described in this release, that the products will receive necessary regulatory approvals, or that they will prove to be commercially successful; nor are there guarantees that regulatory approvals will be sought, or sought within currently expected timeframes, or that contractual milestones will be achieved. For further details and a discussion of these and other risks and uncertainties, see the company's periodic reports, including the annual report on Form 10-K, quarterly reports on Form 10-Q and current reports on Form 8-K, filed with or furnished to the Securities and Exchange Commission. The company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise. Company and Conference Call Information Bristol-Myers Squibb is a global pharmaceutical and related health care products company whose mission is to extend and enhance human life. There will be a conference call on July 24, 2008 at 10:30 a.m. (EDT) during which company executives will address inquiries from investors and analysts. Investors and the general public are invited to listen to a live web cast of the call at www.bms.com/ir or by dialing 913-312-0976, confirmation code 2526349. Materials related to the call will be available at the same website prior to the call. For more information, contact: Brian Henry, 609-252-3337, Communications, Tracy Furey, 609- 252-3208, Communications, John Elicker, 212-546-3775, Investor Relations, or Suketu Desai, 609-252- 5796, Investor Relations. ABILIFY® is the trademark of Otsuka Pharmaceutical Co., Ltd. ATRIPLA™ is a trademark of both Bristol-Myers Squibb Co. and Gilead Sciences, Inc. AVAPRO®, AVALIDE® and PLAVIX® are trademarks of sanofi-aventis ERBITUX® is a trademark of ImClone Systems Incorporated 8
  • 9. BRISTOL-MYERS SQUIBB COMPANY NET SALES BY OPERATING SEGMENTS FOR THE THREE AND SIX MONTHS ENDED JUNE 30, 2008 AND 2007 (Unaudited, dollars in millions) Three Months Six Months Ended June 30, Ended June 30, 2008 2007 2008 2007 Pharmaceuticals $ 4,475 $ 3,851 $ 8,663 $ 7,308 Nutritionals 728 620 1,431 1,226 Net Sales $ 5,203 $ 4,471 $ 10,094 $ 8,534 9
  • 10. BRISTOL-MYERS SQUIBB COMPANY SELECTED PRODUCTS FOR THE THREE AND SIX MONTHS ENDED JUNE 30, 2008 AND 2007 (Unaudited, dollars in millions) The following table sets forth worldwide and U.S. reported net sales for selected products for the three and six months ended June 30, 2008 compared to the three and six months ended June 30, 2007. In addition, the table includes, where applicable, the estimated total U.S. prescription change for the retail and mail-order channels for the comparative periods presented for certain of the company's U.S. pharmaceutical products based on third-party data. A significant portion of the company's U.S. pharmaceutical sales is made to wholesalers. Where changes in reported net sales differ from prescription growth, this change in net sales may not reflect underlying prescriber demand. Worldwide Net Sales U.S. Net Sales % % % Change in U.S. Total 2008 2007 Change 2008 2007 Change Prescriptions vs. 2007 Three Months Ended June 30, Pharmaceuticals Cardiovascular Plavix $ 1,387 $ 1,189 17% $1,207 $ 1,015 19% 11% Avapro/Avalide 335 297 13% 184 170 8% (8)% Pravachol 69 132 (48)% 10 47 (79)% (83)% Virology Reyataz 324 254 28% 159 138 15% 13% Sustiva Franchise (total revenue) 282 233 21% 171 147 16% 13% Baraclude 136 59 131% 35 20 75% 60% Oncology Erbitux 196 162 21% 193 160 21% N/A Taxol 101 95 6% 3 4 (25)% N/A Sprycel 76 35 117% 21 14 50% 44% Ixempra 26 --- --- 26 --- --- N/A Affective (Psychiatric) Disorders Abilify (total revenue) 529 412 28% 403 322 25% 19% Immunoscience Orencia 106 55 93% 87 53 64% N/A Nutritionals Enfamil 287 267 7% 175 177 (1)% N/A 10
  • 11. (Continued) Worldwide Net Sales U.S. Net Sales % % % Change in U.S. Total 2008 2007 Change 2008 2007 Change Prescriptions vs. 2007 Six Months Ended June 30, Pharmaceuticals Cardiovascular 27% Plavix $2,695 $2,127 $2,346 $1,802 30% 37% Avapro/Avalide 640 567 13% 358 333 8% (7)% Pravachol 142 267 (47)% 25 104 (76)% (82)% Virology Reyataz 621 517 20% 319 281 14% 12% Sustiva Franchise (total revenue) 555 459 21% 346 291 19% 14% Baraclude 244 104 135% 64 37 73% 60% Oncology Erbitux 383 322 19% 378 318 19% N/A Taxol 195 206 (5)% 3 8 (63)% N/A Sprycel 142 56 154% 41 24 71% 50% --- Ixempra 51 --- --- 51 --- N/A Affective (Psychiatric) Disorders Abilify (total revenue) 983 778 26% 751 615 22% 17% Immunoscience Orencia 193 96 101% 160 93 72% N/A Nutritionals Enfamil 577 521 11% 358 348 3% N/A 11
  • 12. BRISTOL-MYERS SQUIBB COMPANY CONSOLIDATED STATEMENTS OF EARNINGS FOR THE THREE AND SIX MONTHS ENDED JUNE 30, 2008 AND 2007 (Unaudited, amounts in millions except per share data) Three Months Six Months Ended June 30, Ended June 30, 2008 2007 2008 2007 Net Sales $ 5,203 $ 4,471 $10,094 $ 8,534 Cost of products sold 1,670 1,408 3,240 2,674 Marketing, selling and administrative 1,165 1,103 2,299 2,155 Advertising and product promotion 420 354 739 612 Research and development 826 755 1,608 1,536 Acquired in-process research and development 32 — 32 — Provision for restructuring, net 30 7 41 44 Litigation expense, net 2 14 2 14 Gain on sale of product assets — (26) — (26) Equity in net income of affiliates (150) (128) (314) (254) Other (income)/expense, net (a) (13) (1) 19 21 Total expenses 3,982 3,486 7,666 6,776 Earnings from Continuing Operations 1,221 985 2,428 1,758 Before Minority Interest and Income Taxes Provision for income taxes 258 203 588 243 Minority interest, net of taxes 241 194 471 335 Net Earnings from Continuing Operations 722 588 1,369 1,180 Discontinued Operations: Earnings, net of taxes 42 118 99 216 Loss on Disposal, net of taxes — — (43) — 42 118 56 216 Net Earnings $ 764 $ 706 $ 1,425 $ 1,396 Earnings per Common Share Basic: Net Earnings from Continuing Operations $ 0.37 $ 0.30 $ 0.69 $ 0.60 Discontinued Operations: Earnings, net of taxes 0.02 0.06 0.05 0.11 Loss on Disposal, net of taxes — — (0.02) — Net Earnings per Common Share $ 0.39 $ 0.36 $ 0.72 $ 0.71 Diluted: Net Earnings from Continuing Operations $ 0.36 $ 0.30 $ 0.69 $ 0.60 Discontinued Operations: Earnings, net of taxes 0.02 0.06 0.05 0.11 Loss on Disposal , net of taxes — — (0.02) — Net Earnings per Common Share $ 0.38 $ 0.36 $ 0.72 $ 0.71 Average Common Shares Outstanding: Basic 1,977 1,968 1,976 1,965 Diluted 2,008 2,006 2,007 2,002 (a) Other (income)/expense, net Interest expense $ 80 $ 107 $ 153 $ 216 Interest income (31) (62) (74) (115) Foreign exchange transaction losses (2) (5) 17 3 Other expense, net (60) (41) (77) (83) $ (13) $ (1) $ 19 $ 21 12
  • 13. BRISTOL-MYERS SQUIBB COMPANY SPECIFIED ITEMS FOR THE THREE MONTHS ENDED JUNE 30, 2008 AND 2007 (Unaudited, dollars in millions) Three months ended June 30, 2008 Other Cost of Marketing, Research (income)/ Provision for Litigation expense expense, products selling and and restructuring, net net net Total sold administrative development Productivity Transformation Initiative: Downsizing and streamlining of - - - $ 30 $ - $ - $ 30 worldwide operations $ $ $ Accelerated depreciation and other 58 - - - - - 58 shutdown costs Process standardization - 21 - - - - 21 implementation costs - 30 58 21 - - 109 Litigation Matters: Litigation settlement - - - - 2 - 2 Other: Mead Johnson Nutritionals charges - 1 - - - - 1 Upfront and milestone payments - - 31 - - - 31 Acquired in-process research & development - - 32 - - - 32 Auction rate securities impairment - - - - - (2) (2) $ 58 $ 22 $ 63 $ 30 $ 2 $ (2) 173 Income taxes on items above (34) (Increase)/Decrease to Net Earnings from Continuing Operations $ 139 Three months ended June 30, 2007 Gain Cost of Provision for Litigation on sale of products Research and restructuring, expense, product sold net net development assets Total Litigation Matters: Litigation settlement $ - $ - $ - $ 14 $ - $ 14 Other: Accelerated depreciation 13 - - - - 13 Upfront and milestone payments - 17 - - - 17 Downsizing and streamlining of worldwide operations - - 7 - - 7 Gain on sale of product asset - - - - (26) (26) $ 13 $ 17 $ 7 $ 14 $ (26) 25 Income taxes on items above (5) (Increase)/Decrease to Net Earnings from Continuing Operations $ 20 13
  • 14. BRISTOL-MYERS SQUIBB COMPANY SPECIFIED ITEMS FOR THE SIX MONTHS ENDED JUNE 30, 2008 AND 2007 (Unaudited, dollars in millions) Six months ended June 30, 2008 Marketing, Provision Other selling for (income)/ Research Litigation Cost of products and and restructuring, expense, expense, sold administrative development net net net Total Productivity Transformation Initiative: Downsizing and streamlining of - - - - $ 41 $ - $ 41 worldwide operations $ $ $ $ Accelerated depreciation and other 154 - - - - - 154 shutdown costs Process standardization - 36 - - - - 36 implementation costs Gain on sale and leaseback of - - - - - (9) (9) properties - - 154 36 41 (9) 222 Litigation Matters: Litigation settlement - - - - 2 - 2 Other: Mead Johnson Nutritionals charges - 1 - - - - 1 Product liability - - - - - 16 16 Upfront and milestone payments - - 51 - - - 51 Acquired in-process research & development - - 32 - - - 32 Auction rate securities impairment - - - - - 23 23 $ 154 $ 37 $ 83 $ 41 $ 2 $ 30 347 Income taxes on items above (67) (Increase)/Decrease to Net Earnings from Continuing Operations 280 Six months ended June 30, 2007 Gain on sale of Cost of Research Provision for products and restructuring, Litigation product expense, net sold development net assets Total Litigation Matters: Litigation settlement $ - $ - $ - $ 14 $ - $ 14 Other: Upfront and milestone payments - 97 - - - 97 Downsizing and streamlining of - - 44 - - 44 worldwide operations Accelerated depreciation 29 - - - - 29 Gain on sale of product asset - - - - (26) (26) $ 29 $ 97 $ 44 $ 14 $ (26) 158 Income taxes on items above (45) Change in estimate for taxes on prior year items (39) (Increase)/Decrease to Net Earnings from Continuing Operations $ 74 14
  • 15. BRISTOL-MYERS SQUIBB COMPANY RECONCILIATION OF GAAP RESULTS OF CONTINUING OPERATIONS TO NON-GAAP RESULTS OF CONTINUING OPERATIONS FOR THE THREE MONTHS ENDED JUNE 30, 2008 AND 2007 (Unaudited, amounts in millions except per share data) Q2 2007 Q2 2008 Specified Specified Non Non GAAP GAAP Items* Items* GAAP GAAP Net Sales $ 4,471 $ 5,203 $ 4,471 $ 5,203 Cost of Products Sold 1,408 (13) 1,670 (58) 1,395 1,612 Gross Profit 3,063 13 3,533 58 3,076 3,591 0.3% 1.1% Gross Margin as% of Sales 68.5% 68.8% 67.9% 69.0% Marketing Selling and Admin 1,103 1,165 (22) 1,103 1,143 Advertising and Product Promotion 354 420 354 420 Total SGA 1,457 1,585 (22) 1,457 1,563 (.5%) SG&A as % of Sales 32.6% 32.6% 30.5% 30.0% R&D 755 (17) 826 (31) 738 795 (.4%) (0.6%) R&D as % of Sales 16.9% 16.5% 15.9% 15.3% Acquired in-process research and development 32 (32) - Provision for restructuring, net 7 (7) 30 (30) - - Litigation expense, net 14 (14) 2 (2) - - Gain on sale of Product Assets (26) 26 - - - Equity in Net Income of Affiliates (128) (150) (128) (150) Other (income)/expense, net (1) (13) 2 (1) (11) Earnings from Continuing Operations Before Minority 985 25 1,221 173 Interest & Taxes 1,010 $ 1,394 Provision for income taxes 203 5 258 34 208 292 Effective Tax Rate 20.6% 20.6% 21.1% (.2%) 20.9% Minority Interest, net of taxes 194 241 194 241 Net Earnings - Continuing Operations 588 20 722 139 608 861 Net Earnings - Continuing Operations as a % 13.2% 0.4% 13.6% 13.9% 2.6% 16.5% of sales Net Earnings – Discontinued Ops 118 42 118 42 Net Earnings $ 706 20 $ 764 139 $ 726 $ 903 Interest Exp on Conv. Of Conv Debt Bonds 9 9 4 $ 4 Net Earnings used for Diluted EPS Calc - Continuing Operations. $ 597 20 $ 617 726 139 $ 865 Avg Shares (Diluted) 2,006 2,008 2,006 2,008 Diluted EPS - Continuing Operations $ 0.30 .01 $ 0.36 .07 $ 0.31 $ 0.43 * Please refer to the Specified Items schedules on previous pages for further details. 15