1) A survey was conducted of 826 Macau teenagers (380 males, 446 females) to understand their sexual knowledge and experiences. 2) The results showed that 9.87% of males and 4.48% of females reported having sexual experiences. Most partners were high school or university students of similar ages. 3) For first sexual experiences, 20% of males reported being 16 years old, while 20% of females reported being 17 years old.