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Will Sitting Kill Us?
If So, What Can We Do?
If Not, Why All the Hype?
By
Peter Budnick, PhD, CPE
From the Headlines…

02/14/2014

2

Copyright (c) 2013 Ergoweb Inc.
Overview
 Is there evidence to support these claims?
 Are they overkill?
 What are people and organizations doing

to address this growing concern?
 What might the future bring?
02/14/2014

3

Copyright (c) 2013 Ergoweb Inc.
Theories

 A long-term pattern of sitting for long

durations impacts health and life
expectancy
 Obesity impacts health and life expectancy

02/14/2014

4

Copyright (c) 2013 Ergoweb Inc.
A “Perfect Storm?”

Sources: images.google.com, search for “human evolution”, many sources for this common image; http://www.smart-diner.com/paleo-dietinformation/diseases-of-civilization/, Image attributed to Primal Recipe; Prevent Lifestyle Diseases

02/14/2014

5

Copyright (c) 2013 Ergoweb Inc.
Evidence

 Numerous reports in the popular press, most point to

several primary sources, including:









02/14/2014

Marc T. Hamilton, Deborah G. Hamilton, and Theodore W. Zderic, (2007), Role of low
energy expenditure and sitting in obesity, metabolic syndrome, type 2 diabetes, and
cardiovascular disease, Perspectives in Diabetes.
N Owen, A Bauman, W Brown, (2008), Too much sitting: a novel and important
predictor of chronic disease risk?, British Journal of Sports Medicine, 43:80-81.
Genevieve N. Heally, David W. Dunstan, Jo Salmon, Jonathan E. Shaw, Paul Z Zimmet,
Neville Owen,(2008), Television Time and Continuous Metabolic Risk in Physically
Active Adults, Medicine & Science in Sports & Exercise, 639-645.
Peter T. Katzmarzyk, Timothy S. Church, Coral L. Craig, and Claude Bouchard, (2009),
Sitting Time and Mortality from All Causes, Cardivascular Disease, and Cancer, Medicine
and Science in Sports & Exercise, 998-1005.
Peter T. Katzmarzyk, I-Min Lee, (2012), Sedentary behavior and life expectancy in the
USA: a cause-deleted life table analysis, British Medical Journal, 2:e000828.

6

Copyright (c) 2013 Ergoweb Inc.
Part of a Public Health
Research Agenda
 Many researchers specifically mention updating public

health fitness guidelines, and encouraging the use of
exercise interventions at the clinical level, as part of the
motivation to investigate sedentary behavior.
 Example: “We call upon professionals in clinical medicine,

exercise science and public health to become more
aggressive in implementing exercise treatments for all.”
(British Journal of Sports Medicine Editorial, 2008)

02/14/2014

7

Copyright (c) 2013 Ergoweb Inc.
Hamilton, Hamilton, Zedric
(2008)
 Literature Review
 Should Inactivity Physiology be considered separate and

distinct from Exercise Physiology?
 Comprehensive review of evidence supporting inactivity as

a contributor to various health concerns

02/14/2014

8

Copyright (c) 2013 Ergoweb Inc.
Hamilton, Hamilton, Zedric
(2008)
 “It is easy to forget when studying behaviors (e.g. prolonged

sitting) that statistical correlations with risk factors does not
prove causation and that interventional studies are required
to identify the actual stimuli causing a cellular regulatory
mechanism to raise metabolic risk factors”

02/14/2014

9

Copyright (c) 2013 Ergoweb Inc.
Heally et al (2008) Methods

 Analysis of Australian Diabetes, Obesity and Lifestyle study

(1999-2000)
 Narrowed data set to those who reported 2.5 hrs/week of

moderate to vigorous exercise and where otherwise healthy
(2031 men, 2033 women)
 Applied statistical models looking for correlations

02/14/2014

10

Copyright (c) 2013 Ergoweb Inc.
Heally et al (2008) Key Findings
 Significant associations between TV viewing time and:
 For men and woman,




Waist circumference
Systolic blood pressure
2-h plasma glucose

 For women,
 Fasting plasma glucose
 Triglycerides
 HDL-C

 All associations were stronger for women than for men

02/14/2014

11

Copyright (c) 2013 Ergoweb Inc.
Heally et al (2008) Limitations

 Cross-sectional study
 Self-Reported TV time and physical activity (subjective)
 TV time was the only sedentary behavior investigated
 “Further research, preferably using objective measures, is

required to examine the association of various sedentary
behaviors with metabolic risk.”

02/14/2014

12

Copyright (c) 2013 Ergoweb Inc.
Katzmarzyk et al (2009)
Methods
 Baseline data drawn from 7278 men and 9735 women who

participated in 1981 Canadian Fitness Survey
 Identified survey participants who died between 1981 and

1993 (1832 deaths)
 Applied statistical tests looking for associations

02/14/2014

13

Copyright (c) 2013 Ergoweb Inc.
Katzmarzyk et al (2009) Key
Findings
 Compared with survivors, those who died were significantly:
 Older
 Had higher BMI
 Were less physically active

 Daily time spent sitting was associated with elevated risk for:
 All-cause deaths
 Cardiovascular disease
 Association of sitting time and death was independent of leisure

time physical activity and BMI

02/14/2014

14

Copyright (c) 2013 Ergoweb Inc.
Katzmarzyk et al (2009)
Limitations
 Baseline participants were not screened for pre-existing

disease
 Self-reported sitting behavior (subjective)
 Sitting time data available only at 1981 baseline

02/14/2014

15

Copyright (c) 2013 Ergoweb Inc.
Katzmarzyk & Lee (2012)
Methods
 Meta-analysis of studies that investigated associations

between sitting or TV viewing and all-cause mortality (5
articles)
 Applied statistical models

02/14/2014

16

Copyright (c) 2013 Ergoweb Inc.
Katzmarzyk & Lee (2012) Key
Findings
 Limiting sitting time to <3 hrs/day “may increase life

expectancy at birth in the USA by approximately” 2.0 years
 Limiting TV viewing time to <2 hrs/day “may increase life

expectancy at birth in the USA by approximately” 1.38 years
 “… assuming a causal relationship.”
 Compared to smoking risk: 2.5 yr reduction for men; 1.8 for

women
02/14/2014

17

Copyright (c) 2013 Ergoweb Inc.
Katzmarzyk & Lee (2012)
Limitations
 “… confounders associated with both sedentary behaviour

and premature mortality may have been unmeasured or
inadequately adjusted for in the primary studies …”
 Results cannot be applied to individuals within the

population, only to the population at large.
 Subjective data sets – still need to do objective intervention

studies

02/14/2014

18

Copyright (c) 2013 Ergoweb Inc.
Sitting “Risk” in Perspective

 Lots of things have potential to impact health of shorten

population life expectancy

 Average life expectancy has increased dramatically, in parallel

with our increased amount of sitting

 A public health guideline instructing people to change their

sedentary behavior, including sitting, is much the same as the
current guidelines that we should get moderate to vigorous
exercise for at least 150 minutes per week …

 How many of us do that?

02/14/2014

19

Copyright (c) 2013 Ergoweb Inc.
In Summary

 My review of the literature suggests more physical activity is better

than less physical activity – no surprise

 The real challenge is influencing human behavior

 Moderate to vigorous activity for at least 150 mins/wk is good
 So is increasing light physical activities – simple movements

throughout the day

 Sitting won’t kill you, but if you do it too much, it could impact your

health, and therefore your life expectancy, but no one can say for sure

02/14/2014

20

Copyright (c) 2013 Ergoweb Inc.
Are Concerns About Sitting
New?
 Example: Ramazinni (1700’s)
 "Those who sit at their work suffer from their own particular

diseases.”
 "Those who work standing . . .carpenters, sawyers, carvers,

blacksmiths, masons . . .are liable to varicose veins. . . [because]
the strain on the muscles is such that the circulation of the blood
is retarded.”
 "Standing even for a short time proves exhausting compared with

walking and running though it be for a long time. . . . Nature
delights and is restored by alternating and varied actions.”
02/14/2014

21

Copyright (c) 2013 Ergoweb Inc.
But, it’s NOT Just about Work

 People sit …
 At home
 At leisure

 On their way to and from

home, leisure and work
 And at work

02/14/2014

22

Copyright (c) 2013 Ergoweb Inc.
What Are our Options?

 Personal behavior changes – it’s not just about work
 Cultural changes
 Institutional changes – what can we do in the workplace?

02/14/2014

23

Copyright (c) 2013 Ergoweb Inc.
Politics

 the AMA adopted policy recognizing potential risks of

prolonged sitting and encouraging employers, employees
and others to make available alternatives to sitting, such as
standing work stations and isometric balls.

02/14/2014

24

Copyright (c) 2013 Ergoweb Inc.
Solutions

 Passive ergonomics design
 Dynamic ergonomics design
 Active ergonomics design
 Work flow design
 Behavior changes

02/14/2014

25

Copyright (c) 2013 Ergoweb Inc.
Practical Challenges

 “What’s the best way to sit?”
 “What’s the best way to stand?”
 “What’s the best way to move …”

02/14/2014

26

Copyright (c) 2013 Ergoweb Inc.
Institutional Challenges

 Culture
 Cost
 Change is never easy

02/14/2014

27

Copyright (c) 2013 Ergoweb Inc.
So, In Conclusion, Will Sitting
Kill You?
 Probably not
 Put the potential risk in perspective
 But yes, do move more often throughout your day

02/14/2014

28

Copyright (c) 2013 Ergoweb Inc.
Scott Adams -- Dilbert

02/14/2014

29

Copyright (c) 2013 Ergoweb Inc.
Special Thanks to …

 Gen Kay
 Dan MacLeod
 Rachel Michael
 Brian Peacock

02/14/2014

30

Copyright (c) 2013 Ergoweb Inc.
Thank You

Peter Budnick, PhD, CPE
Ergoweb® Inc., ErgoAdvocate® LLC, Ergobuyer® LLC
435-214-4266
budnick@ergoweb.com

02/14/2014

31

Copyright (c) 2013 Ergoweb Inc.

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Will sitting kill us?

  • 1. Will Sitting Kill Us? If So, What Can We Do? If Not, Why All the Hype? By Peter Budnick, PhD, CPE
  • 3. Overview  Is there evidence to support these claims?  Are they overkill?  What are people and organizations doing to address this growing concern?  What might the future bring? 02/14/2014 3 Copyright (c) 2013 Ergoweb Inc.
  • 4. Theories  A long-term pattern of sitting for long durations impacts health and life expectancy  Obesity impacts health and life expectancy 02/14/2014 4 Copyright (c) 2013 Ergoweb Inc.
  • 5. A “Perfect Storm?” Sources: images.google.com, search for “human evolution”, many sources for this common image; http://www.smart-diner.com/paleo-dietinformation/diseases-of-civilization/, Image attributed to Primal Recipe; Prevent Lifestyle Diseases 02/14/2014 5 Copyright (c) 2013 Ergoweb Inc.
  • 6. Evidence  Numerous reports in the popular press, most point to several primary sources, including:      02/14/2014 Marc T. Hamilton, Deborah G. Hamilton, and Theodore W. Zderic, (2007), Role of low energy expenditure and sitting in obesity, metabolic syndrome, type 2 diabetes, and cardiovascular disease, Perspectives in Diabetes. N Owen, A Bauman, W Brown, (2008), Too much sitting: a novel and important predictor of chronic disease risk?, British Journal of Sports Medicine, 43:80-81. Genevieve N. Heally, David W. Dunstan, Jo Salmon, Jonathan E. Shaw, Paul Z Zimmet, Neville Owen,(2008), Television Time and Continuous Metabolic Risk in Physically Active Adults, Medicine & Science in Sports & Exercise, 639-645. Peter T. Katzmarzyk, Timothy S. Church, Coral L. Craig, and Claude Bouchard, (2009), Sitting Time and Mortality from All Causes, Cardivascular Disease, and Cancer, Medicine and Science in Sports & Exercise, 998-1005. Peter T. Katzmarzyk, I-Min Lee, (2012), Sedentary behavior and life expectancy in the USA: a cause-deleted life table analysis, British Medical Journal, 2:e000828. 6 Copyright (c) 2013 Ergoweb Inc.
  • 7. Part of a Public Health Research Agenda  Many researchers specifically mention updating public health fitness guidelines, and encouraging the use of exercise interventions at the clinical level, as part of the motivation to investigate sedentary behavior.  Example: “We call upon professionals in clinical medicine, exercise science and public health to become more aggressive in implementing exercise treatments for all.” (British Journal of Sports Medicine Editorial, 2008) 02/14/2014 7 Copyright (c) 2013 Ergoweb Inc.
  • 8. Hamilton, Hamilton, Zedric (2008)  Literature Review  Should Inactivity Physiology be considered separate and distinct from Exercise Physiology?  Comprehensive review of evidence supporting inactivity as a contributor to various health concerns 02/14/2014 8 Copyright (c) 2013 Ergoweb Inc.
  • 9. Hamilton, Hamilton, Zedric (2008)  “It is easy to forget when studying behaviors (e.g. prolonged sitting) that statistical correlations with risk factors does not prove causation and that interventional studies are required to identify the actual stimuli causing a cellular regulatory mechanism to raise metabolic risk factors” 02/14/2014 9 Copyright (c) 2013 Ergoweb Inc.
  • 10. Heally et al (2008) Methods  Analysis of Australian Diabetes, Obesity and Lifestyle study (1999-2000)  Narrowed data set to those who reported 2.5 hrs/week of moderate to vigorous exercise and where otherwise healthy (2031 men, 2033 women)  Applied statistical models looking for correlations 02/14/2014 10 Copyright (c) 2013 Ergoweb Inc.
  • 11. Heally et al (2008) Key Findings  Significant associations between TV viewing time and:  For men and woman,    Waist circumference Systolic blood pressure 2-h plasma glucose  For women,  Fasting plasma glucose  Triglycerides  HDL-C  All associations were stronger for women than for men 02/14/2014 11 Copyright (c) 2013 Ergoweb Inc.
  • 12. Heally et al (2008) Limitations  Cross-sectional study  Self-Reported TV time and physical activity (subjective)  TV time was the only sedentary behavior investigated  “Further research, preferably using objective measures, is required to examine the association of various sedentary behaviors with metabolic risk.” 02/14/2014 12 Copyright (c) 2013 Ergoweb Inc.
  • 13. Katzmarzyk et al (2009) Methods  Baseline data drawn from 7278 men and 9735 women who participated in 1981 Canadian Fitness Survey  Identified survey participants who died between 1981 and 1993 (1832 deaths)  Applied statistical tests looking for associations 02/14/2014 13 Copyright (c) 2013 Ergoweb Inc.
  • 14. Katzmarzyk et al (2009) Key Findings  Compared with survivors, those who died were significantly:  Older  Had higher BMI  Were less physically active  Daily time spent sitting was associated with elevated risk for:  All-cause deaths  Cardiovascular disease  Association of sitting time and death was independent of leisure time physical activity and BMI 02/14/2014 14 Copyright (c) 2013 Ergoweb Inc.
  • 15. Katzmarzyk et al (2009) Limitations  Baseline participants were not screened for pre-existing disease  Self-reported sitting behavior (subjective)  Sitting time data available only at 1981 baseline 02/14/2014 15 Copyright (c) 2013 Ergoweb Inc.
  • 16. Katzmarzyk & Lee (2012) Methods  Meta-analysis of studies that investigated associations between sitting or TV viewing and all-cause mortality (5 articles)  Applied statistical models 02/14/2014 16 Copyright (c) 2013 Ergoweb Inc.
  • 17. Katzmarzyk & Lee (2012) Key Findings  Limiting sitting time to <3 hrs/day “may increase life expectancy at birth in the USA by approximately” 2.0 years  Limiting TV viewing time to <2 hrs/day “may increase life expectancy at birth in the USA by approximately” 1.38 years  “… assuming a causal relationship.”  Compared to smoking risk: 2.5 yr reduction for men; 1.8 for women 02/14/2014 17 Copyright (c) 2013 Ergoweb Inc.
  • 18. Katzmarzyk & Lee (2012) Limitations  “… confounders associated with both sedentary behaviour and premature mortality may have been unmeasured or inadequately adjusted for in the primary studies …”  Results cannot be applied to individuals within the population, only to the population at large.  Subjective data sets – still need to do objective intervention studies 02/14/2014 18 Copyright (c) 2013 Ergoweb Inc.
  • 19. Sitting “Risk” in Perspective  Lots of things have potential to impact health of shorten population life expectancy  Average life expectancy has increased dramatically, in parallel with our increased amount of sitting  A public health guideline instructing people to change their sedentary behavior, including sitting, is much the same as the current guidelines that we should get moderate to vigorous exercise for at least 150 minutes per week …  How many of us do that? 02/14/2014 19 Copyright (c) 2013 Ergoweb Inc.
  • 20. In Summary  My review of the literature suggests more physical activity is better than less physical activity – no surprise  The real challenge is influencing human behavior  Moderate to vigorous activity for at least 150 mins/wk is good  So is increasing light physical activities – simple movements throughout the day  Sitting won’t kill you, but if you do it too much, it could impact your health, and therefore your life expectancy, but no one can say for sure 02/14/2014 20 Copyright (c) 2013 Ergoweb Inc.
  • 21. Are Concerns About Sitting New?  Example: Ramazinni (1700’s)  "Those who sit at their work suffer from their own particular diseases.”  "Those who work standing . . .carpenters, sawyers, carvers, blacksmiths, masons . . .are liable to varicose veins. . . [because] the strain on the muscles is such that the circulation of the blood is retarded.”  "Standing even for a short time proves exhausting compared with walking and running though it be for a long time. . . . Nature delights and is restored by alternating and varied actions.” 02/14/2014 21 Copyright (c) 2013 Ergoweb Inc.
  • 22. But, it’s NOT Just about Work  People sit …  At home  At leisure  On their way to and from home, leisure and work  And at work 02/14/2014 22 Copyright (c) 2013 Ergoweb Inc.
  • 23. What Are our Options?  Personal behavior changes – it’s not just about work  Cultural changes  Institutional changes – what can we do in the workplace? 02/14/2014 23 Copyright (c) 2013 Ergoweb Inc.
  • 24. Politics  the AMA adopted policy recognizing potential risks of prolonged sitting and encouraging employers, employees and others to make available alternatives to sitting, such as standing work stations and isometric balls. 02/14/2014 24 Copyright (c) 2013 Ergoweb Inc.
  • 25. Solutions  Passive ergonomics design  Dynamic ergonomics design  Active ergonomics design  Work flow design  Behavior changes 02/14/2014 25 Copyright (c) 2013 Ergoweb Inc.
  • 26. Practical Challenges  “What’s the best way to sit?”  “What’s the best way to stand?”  “What’s the best way to move …” 02/14/2014 26 Copyright (c) 2013 Ergoweb Inc.
  • 27. Institutional Challenges  Culture  Cost  Change is never easy 02/14/2014 27 Copyright (c) 2013 Ergoweb Inc.
  • 28. So, In Conclusion, Will Sitting Kill You?  Probably not  Put the potential risk in perspective  But yes, do move more often throughout your day 02/14/2014 28 Copyright (c) 2013 Ergoweb Inc.
  • 29. Scott Adams -- Dilbert 02/14/2014 29 Copyright (c) 2013 Ergoweb Inc.
  • 30. Special Thanks to …  Gen Kay  Dan MacLeod  Rachel Michael  Brian Peacock 02/14/2014 30 Copyright (c) 2013 Ergoweb Inc.
  • 31. Thank You Peter Budnick, PhD, CPE Ergoweb® Inc., ErgoAdvocate® LLC, Ergobuyer® LLC 435-214-4266 budnick@ergoweb.com 02/14/2014 31 Copyright (c) 2013 Ergoweb Inc.