The document discusses a theory about cancer (carcinogenesis) and mitochondria in cancer cells. It suggests that cancer cells have many mutations in mitochondrial DNA. The production of nitric oxide and superoxide as free radicals can lead to peroxynitrite radicals that break down, inhibit, or suppress mitochondria. Since most ATP is produced in mitochondria, this impacts cellular metabolic activity. Accumulation of lipids in the mitochondrial matrix can cause breakdown of the carnitine shuttle and exceed the capacity of beta-oxidation, later producing ketone bodies that inhibit glycolysis and inefficiently mobilize triglycerides from adipose tissue for energy. Mitochondria also experience destruction and calcium ion mobilization.

1. “EFRUZHU
CANCER (CARCİNOGENESİS) THEORY”
MİTHOCHONDRİON İN CANCER CELL .
DETAİLED COMMENTS 14. = VOİCED 14.
CANCER CELL HAS A LOT OF MUTATİONS İNTO MİTHOCHONDRİAL
DNA,NİTRİC OXİDE AND SUPER OXİDE BOTH OF THESE AS FREE
RADİCAL=OXİDANCE REACTİON PRODUCT DERİVED PEROXYNİTRİT
RADİCALE THAT BREAK DOWN/İNHİBİTİON/SUPRESSİON OF
MİTHOCHONDRİON.MOST OF THE ATP ARE PRODUCİNG FROM HERE
THAT NEED CELLULAR METABOLİC ACTİVİTY .ACCUMULATİON THE
LİPİD İN THE MATRİX CAUSE OF CARNİTİNE SHUTLE
BREAK/DEGENERATE,TO PASS OVER CAPACİTY OF B-XİDATİON,LATER
TO CARRY PRODUCİNG KETONE BODİES (İNHİBİTİNG GLYCOLYSİS VİA
PHOSFOFRUCTOKİNASE),İNEFFİCİENT ENERGY CONDİTİON ADİPOSE
TİSSUE MOBİLİSATİON TRİGLİSERİDE FOR ENERGY
PURPOSE.MİTHOCHONDRİON HAS DESTRUCTİON AND CALCİUM
İONS MOBİLİSATİON(MİTHOCHONDRİON MEBRANE