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Can Alkaline
destroy
Coronavirus?
C o n f o r m a t i o n a l C h a n g e o f t h e C o r o n a vi r u s
P e p l o m e r G l y c o p r o t e i n a t p H 8 . 0 a n d 3 7 ° C
C o r r e l a t e s w i t h Vi r u s Ag g r e g a t i o n a n d
Vi r u s - I n d u c e d C e l l F u s i o n ( 1 9 9 0 )
WadsworthCenterforLaboratoriesandResearch,New
YorkStateDepartmentofHealth,
DepartmentofBiomedicalSciences,SchoolofPublic
Health,UniversityatAlbany,StateUniversityofNewYork,
Albany,NewYork12201-0509
DepartmentofPathology,UniformedServicesUniversity
oftheHealthSciences,Bethesda,Maryland208142
L AW R E N C E S . S T U R M AN ,
C Y N T H I A S . R I C AR D
K AT H RY N V. H O L M E S
Comparison slide
COMPARISON POINT 1
pH 6.0 Acidic Environment
Coronavirus stable
High Infectiliy
COMPARISON POINT 2
pH 8.0 – Alkaline Environment
Coronavirus – aggregate
Loss its ability to infect
碱性能破坏冠状病
毒吗?
p H 8 . 0 和 3 7 ° C 时 冠 状 病 毒 P e p l o m e r 糖 蛋 白 的 构 象
变 化 与 病 毒 聚 集 和 病 毒 诱 导 的 细 胞 融 合 有 关 ( 1 9 9 0 )
纽约州卫生部沃兹沃思实验室与研究中心
生物医学科学系
奥尔巴尼大学公共卫生学院,纽约州立大
学,奥尔巴尼,纽约12201-0509
统一服务卫生大学病理学系科学,贝塞斯
达,马里兰州208142
L AW R E N C E S . S T U R M AN ,
C Y N T H I A S . R I C AR D
K AT H RY N V. H O L M E S
Comparison slide
COMPARISON POINT 1
pH 6.0酸性环境
冠状病毒稳定高传染性
COMPARISON POINT 2
pH 8.0 –碱性环境
冠状病毒–聚集体
失去感染能力

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Alkaline can destroy coronavirus