Breast Ca Stagings and Management.pptx
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Lecture notes for medical students
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Breast Ca Stagings and Management.pptx
- 1. Tips on using my ppt. 1. You can freely download, edit, modify and put your name etc. 2. Don’t be concerned about number of slides. Half the slides are blanks except for the title. 3. First show the blank slides (eg. Aetiology ) > Ask students what they already know about ethology of today's topic. > Then show next slide which enumerates aetiologies. 4. At the end rerun the show – show blank> ask questions > show next slide. 5. This will be an ACTIVE LEARNING SESSION x three revisions. 6. Good for self study also. 7. See notes for bibliography.
- 2. Stage TNM • 0 • I • IIA • IIB • Tis N0, M0 • T1, N0, M0 • T0, N1,MO • T1,N1,M0 • T2,NO,M0 • T2,N1,MO • T3,NO,MO
- 3. Stage TNM • IIIA • IIIB • IIIC • IV • T0 -- T3,N1/N2,MO • T4,N1/2,MO • AnyT,N3,M0 • AnyT,AnyN,,M1
- 5. Primary Tumor (T) TX Primary tumor cannot be assessed T0 No evidence of primary tumor Tis Carcinoma in situ T1 >2cm T2 2-5cm T3 >5cm T4 fixed to chest wall or skin
- 6. Regional Lymph Nodes (N)
- 7. Regional Lymph Nodes (N) • NX Regional lymph nodes cannot be assessed (e.g.,previously removed) • N0- No regional lymph node metastases • N1- Metastases to movable ipsilateral • N2- Metastases in ipsilateral level I, II axillary lymph nodes that are clinically fi xed or matted • N3- Metastases in ipsilateral infraclavicular lymph node(s) ,ipsilateral internal mammary lymph node(s) ,ipsilateral supraclavicular lymph node(s)
- 8. Regional Lymph Nodes (N)
- 9. Regional Lymph Nodes (N) Level of Lymph nodes • Level I --Lateral to P. Minor • Level II –Deep to P.Minor • Level III – Medial to Minor
- 10. Metastasis
- 11. Metastasis • Mx –Cannot be assesed • Mo- No Mets • M1- Mets +nt
- 12. Treatment
- 13. Treatment • Local Therapy – Surgery – Radiotherapy • Systemic Therapy – Chemotherapy – Hormonal – Targeted Therapy- Herceptin (Monoclonal antibody)
- 14. Treatment • Local disease- Local Tt. Followed by systemic • Systemic disease- Systemic Tt. followed by local tt
- 15. In Situ Breast Cancer (Stage 0) • Conservative surgery +-RT
- 16. Early Invasive Breast Cancer (Stage I, IIa, or IIb)
- 17. Early Invasive Breast Cancer (Stage I, IIa, or IIb) • MRM is standard • Breast conservation +Axillary dissection+RT • Sentinel Lymph node biopsy • Adjuvant Chemo for node positive • Tamoxifen
- 18. Advanced Locoregional Regional Breast Cancer (Stage IIIa or IIIb)
- 19. Advanced Locoregional Regional Breast Cancer (Stage IIIa or IIIb) • Operable-MRM+Adj.Chemo+RT • Inoperable –Neoadj. Chemo>MRM>RT
- 20. Distant Metastases (Stage IV) • Palliative Chemo/Hormonal
- 21. Receptor Status
- 22. Receptor Status • Oestrogen, Progesteron -Tamoxifen • HER2/Neu (Human Epidermal Growth factor) Receptor- Herceptin (Monoclonal antibody)
- 23. Get this ppt in mobile 1. Download Microsoft PowerPoint from play store. 2. Open Google assistant 3. Open Google lens. 4. Scan qr code from next slide.
- 24. Get this ppt in mobile
- 25. Get my ppt collection • https://www.slideshare.net/drpradeeppande/ edit_my_uploads • https://www.dropbox.com/sh/x600md3cvj8 5woy/AACVMHuQtvHvl_K8ehc3ltkEa?dl =0 • https://www.facebook.com/doctorpradeeppa nde/?ref=pages_you_manage