1. Diabetic foot ulcers are a common complication of diabetes, with an annual incidence of 1-4% and lifetime risk of 15-25%. Approximately 15% of diabetic foot ulcers result in lower extremity amputation. 2. Peripheral neuropathy is a major contributing factor in diabetic foot ulcers. The costs to treat a diabetic foot ulcer over a 2 year period following detection can be significant. 3. Five-year mortality rates for diabetes-related wounds and amputations are worse than some forms of cancer. Comprehensive diabetic foot examinations and appropriate footwear can help prevent ulcers.