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Blockchain Technology in Healthcare
The Revolution Starts Here
Matthias Mettler
M.A. HSG
Boydak Strategy Consulting AG
Freienbach, Switzerland
mettler.matthias@bluewin.ch
Abstract—Blockchain technology has shown its considerable
adaptability in recent years as a variety of market sectors sought
ways of incorporating its abilities into their operations. While so
far most of the focus has been on the financial services industry,
several projects in other service related areas such as healthcare
show this is beginning to change. Numerous starting points for
Blockchain technology in the healthcare industry are the focus of
this report. With examples for public healthcare management,
user-oriented medical research and drug counterfeiting in the
pharmaceutical sector, this report aims to illustrate possible
influences, goals and potentials connected to this disruptive
technology.
Keywords—Blockchain, new business models, digitalization,
healthcare, digital health, health information management, medical
treatment, patient data, medical research, counterfeit drugs
I. INTRODUCTION
Blockchain is causing a hype and optimism that has rarely
been seen in the history of technology. It is celebrated as a new
technological revolution, which will have at least as large an
impact on society as the invention of the wheel, the steam
engine or the Internet. In a World Economic Forum report
released in September 2015, 58 percent of all survey
respondents said that they expected that by the year 2025, 10
percent of global gross domestic product will be stored using
Blockchain technology [1]. It is therefore not surprising that
Blockchain is attracting throngs of investors who are
extensively investing in Blockchain startups. The investments
amounted to almost half a billion dollars in 2015 [2] – the trend
increasing. Nevertheless, the approaches, objectives and
potentials of Blockchain are still largely unknown throughout
society.
II. BITCOINS AS A STARTING POINT FOR
THE DEVELOPMENT OF BLOCKCHAIN
Blockchain was originally developed for the crypto-
currency Bitcoin and first described in Satoshi Nakamoto's
(pseudonym) whitepaper in 2008. In the document, Nakamoto
particularly addresses the challenge of ownership related to
digital currencies and proposes a solution using a Blockchain
prior to the settlement of transactions [3].
The functional principle of the Blockchain can be explained
using the concept of such Bitcoin transactions. The Bitcoin
Blockchain can be considered as a cohesive collection of
digital wallets [4]. If a Bitcoin transaction, for example, is
made from wallet A to wallet B, this information is
simultaneously shared with all other wallets in the underlying
Bitcoin Blockchain. The information on a Bitcoin transaction
(e.g. transferred sum, ownership, etc.) are combined in an
information block, marked with a timestamp and added as a
new block to the existing Bitcoin Blockchain. At the same
time, the transaction is verified and confirmed by all involved
wallets. Due to this continuous sequence of blocks of
information, the information with respect to all transactions
made in the past, at any given time, are completely transparent
and literally tamper-proof [4] [5].
Put simply, the solution of ownership associated with
Bitcoins as published by Satoshi Nakamoto [3], therefore, lies
in consolidating all necessary information in a single database,
which is then publicly distributed [4] [5]. A database that does
not claim any ownership and simultaneously, everyone owns.
The content of this decentralized database is available to all
parties involved. Furthermore, since all transactions are
processed by users via a particular pseudonym, the information
contained in the Bitcoin Blockchain is completely anonymous
[4] [5].
III. BLOCKCHAIN POTENTIAL EXTENDS
FAR BEYOND THE FINANCIAL SECTOR
The Bitcoin Blockchain example clearly shows that
Blockchain technology represents an approach as to how
ownership of digital goods can be achieved. The underlying
principle of decentralized, transparent and instant access to
information represents a starting point for many market
sectors [5] [6]. This may also be considered a reason why, in
recent years, Blockchain has continued to develop both within
and outside of the financial sector. Consequently, there are
some interesting examples outside of the financial sector.
Startups like Ujo or Peertraks offer a new approach, such as
how music rights can be administered and enforced using
Blockchain. Or at Stampery, for example, contracts, emails
and documents can be signed digitally and smart contracts can
be settled. Also, in the healthcare industry there are various
possibilities: for example, in (public) health management, in
the pharmaceutical sector, in medical research or in consumer-
2016 IEEE 18th International Conference on e-Health Networking, Applications and Services (Healthcom)
978-1-5090-3370-6/16/$31.00 ©2016 IEEE
oriented healthcare [6]. Below there are certain examples from
the healthcare industry which highlight the importance of
Blockchain and its functionality.
IV. SMART HEALTHCARE MANAGEMENT
FOR THE BENEFIT OF THE PATIENT
A decentralized database which is consistently held up to
date presents many advantages to the healthcare industry.
These advantages become especially interesting, when many
different parties need access to the same information [6] [7]
[8]. Medical treatment processes, for example in the area of
elderly care or chronic diseases, are predestined fields of
application where Blockchain technology can create added
value. A variety of involved parties (e.g., general practitioners,
medical specialists, hospitals, therapists, etc.) and the amount
of media disruptions involved during the treatment of a patient
(e.g., change of communication media, various medical health
records, incompatible IT interfaces, etc.) can lead to time-
consuming and resource-intensive authentication and
information processes for all medical stakeholders involved
[6].
For example, Gem, a US startup, is actively involved in this
area and, therefore, launched the Gem Health Network based
on the Ethereum Blockchain technology [7]. Through this
shared network infrastructure, different healthcare specialists
can access the same information. This will also permit the
development of a new class of Blockchain-based applications
in healthcare that will unlock wasted resources and solve
important operational problems [7].
Therefore, the Gem Health Network represents a healthcare
ecosystem that combines both businesses, individuals and
experts and which, at the same time, improve patient-centered
care while address operational efficiency issues. This network
is thus an example of a Blockchain approach that provides all
relevant medical stakeholders transparent and clear access to
the latest treatment information. On the one hand, this can
limit medical negligence due to outdated information and
thereby prevent health issues in an early stage. This can lead
to extensive savings in merit costs. On the other hand, it
allows medical experts involved to track the interactions
between the patient and all physicians which have taken place
in the past. Consequently, the entire treatment of a patient is
characterized in a transparent manner, whereby a completely
new information and confidence level between all medical
stakeholders is created.
The fact that this logic proves itself correct not only for
direct patient-physician relationships, can be demonstrated by
the example of Estonia’s digital health infrastructure. In 2011,
Estonia collaborated with Guardtime which operates a
healthcare platform based on Blockchain technology [9].
Since then, Estonian citizens, healthcare providers or health
insurance companies have been able to retrieve all information
on medical treatments performed in Estonia by using the
Guardtime Blockchain [9]. Estonia thus has proven that a
complete public health infrastructure can be operated using
Blockchain.
V. BLOCKCHAIN EMPOWERS END USERS
RESPECTIVELY PATIENTS IN HEALTHCARE
Data is the new gold – this also applies to patient-generated
health data. The abundance of available worldwide health apps
and health wearables leads to a powerful flood of data, which
can be used for medical issues related research. Blockchain
offers various application possibilities in the field of patient-
generated health data [6].
For example, healthbank, a global Swiss digital health
startup, takes a radically new approach when it comes to the
handling of data transactions and sharing of personal health
data. This startup offers its users a platform on which they can
store and manage their health information in a secure
environment [10]. The data sovereignty lies fully in the hands
of the user. As a next step, healthbank plans to consistently
apply and implement Blockchain technology for the
underlying business model [10]. Using Blockchain, in the
future, personal patient-generated health data (e.g., heart rate,
blood pressure, medicines taken, sleep patterns, eating habits
etc.) can be retrieved from health apps, wearables or physician
visits and be securely stored in the healthbank Blockchain.
Already today, healthbank users are not only able to save
their data on the platform, but can also make it available for
medical research. In return, they receive specific financial
compensation for their data provided. Healthbank thereby
becomes a unique data-trading platform, with which new
opportunities in patient-oriented research are made available
(e.g., in clinical trials for the pharmaceutical industry, in
academic research projects at universities, etc.). Using
Blockchain, this model could be even further individualized in
a way that personal patient-generated health data which is
available to researchers can be tracked in the research process
with a timestamp (e.g., analogue to the described Bitcoin
transaction) [6] [8]. Healthbank users who have significantly
contributed to the success of medical research projects could
be identified using Blockchain and rewarded at a higher level
than the average.
Healthbank has thereby become a symbol of end user
respectively patient empowerment in healthcare which rides
alongside digitalization, new digital business models and
digital health initiatives. Blockchain technology will further
boost this end user and patient empowerment in healthcare.
VI. USING BLOCKCHAIN TO FIGHT COUNTERFEIT
DRUGS IN THE PHARMACEUTICAL INDUSTRY
Wherever products are subject to a sensitive production
process and where extensive reputational and liability issues
are associated with the final product, the benefits of
Blockchain are evident. Therefore, the research, development
2016 IEEE 18th International Conference on e-Health Networking, Applications and Services (Healthcom)
and production of drugs in the pharmaceutical sector is a
further field of application for Blockchain technology.
Corresponding to the previously described example referring
to Bitcoin transactions via Blockchain, this technology can
also be used to monitor the production processes for drugs.
In this context, the issue of counterfeit medicine is an
urgent and increasingly acute worldwide issue. According to
the World Health Organization, ten percent of drugs are
counterfeit worldwide, in developing countries the number
rises up to 30 percent [11]. Such counterfeit drugs often do not
only affect so-called lifestyle products (e.g., muscle building
supplements, potency stimulants, slimming products, etc.), but
also drugs for the treatment of cardiovascular disorders and
cancer, antibiotics, painkillers, contraceptives and other
prescription drugs [11]. Such counterfeits can contain the
correct active ingredient, but in most cases show a dose which
is too high or too low or which are produced in an impure
manner. It then becomes extremely dangerous for the human
organism when there is no trace of the expected active
substance in the forged drug [11].
Hyperledger, a research network across industries, recently
launched the Counterfeit Medicines Project [12]. The project
especially focuses on the issue of drug counterfeiting and is
one of the current use cases within the research network, in
which Accenture, Cisco, Intel, IBM, Block Stream and
Bloomberg are involved [12]. As part of this project, each
drug produced is marked with a timestamp. Firstly, thanks to
this approach, it is possible to determine when and where the
drug was produced at any given time. Secondly, such an
approach can be specifically used to fight the production of
counterfeit drugs. Using Blockchain, the origin of the product
and its components are detected, and any transfer of
ownership in each case is made clear and available to
everyone. Forged, poor quality or stolen goods can be tracked
and identified.
In this field of application, Blockchain contributes to
ensuring that safety in relation to drugs is increased, and
health-related follow-up costs are reduced.
VII. CONCLUSION
The examples described, show that Blockchain offers
numerous opportunities for usage in the healthcare sector, e.g.
in public health management, user-oriented medical research
based on personal patient data as well as drug counterfeiting.
The immense potential of this technology shows up
wherever, until now, a trusted third party was necessary for
the settlement of market services. With Blockchain, direct
transactions suddenly become possible, whereby a central
actor, who controlled the data, earned commission or even
intervened in a censoring fashion, can be eliminated.
This disruptive character, which underlies Blockchain
technology, will strongly affect the balance of power between
existing market players in healthcare. It will also promote new
digital business models and digital health initiatives. Due to the
fact that, in the future, (data) intermediaries can be avoided,
this technology opens new doors with respect to how market
interactions in healthcare can be conducted. Blockchain thus
has an immense potential for the future and will show
disruptive changes in the healthcare industry.
REFERENCES
[1] World Economic Forum (2015, September). Deep Shift. Technology
Tipping Points and Societal Impact, [Online]. Available:
http://www3.weforum.org/docs/WEF_GAC15_Technological_Tipping_
Points_report_2015.pdf.
[2] E. Maras (2016, March), VC Fintech Funding Sets Record In 2015,
[Online]. Available: https://www.cryptocoinsnews.com/vc-fintech-
funding-sets-record-2015-fueling-bitcoin-blockchain-growth/
[3] N. Satoshi (2008), Bitcoin: A Peer-to-Peer Electronic Cash System,
[Online]. Available: https://bitcoin.org/bitcoin.pdf
[4] G. Dwyer. “The economics of Bitcoin and similar private digital
currencies,” Journal of Financial Stability, vol. 17, pp. 81-91, April
2015.
[5] R. Böhme, N. Christin, B. Edelman, and T. Moore. “Bitcoin:
Economics, Technology, and Governance,” Journal of Economic
Perspectives, vol. 29, no. 2, pp. 213-38, May 2015.
[6] M. Swan, Blockchain: Blueprint for a new economy. O'Reilly Media,
Inc., 2015.
[7] G. Prisco (2016, April), The Blockchain for Healthcare: Gem Launches
Gem Health Network With Philips Blockchain Lab, [Online]. Available:
https://bitcoinmagazine.com/articles/the-blockchain-for-heathcare-gem-
launches-gem-health-network-with-philips-blockchain-lab-1461674938
[8] G. Irving, H. John (2016, May), How blockchain-timestamped protocols
could improve the trustworthiness of medical science. [Online].
Available: http://f1000research.com/articles/5-222/v2
[9] O. Williams-Grut (2016, March), Estonia is using the technology behind
bitcoin to secure 1 million health records, [Online]. Available:
http://www.businessinsider.com/guardtime-estonian-health-records-
industrial-blockchain-bitcoin-2016-3?r=UK&IR=T.
[10] P. B. Nichol (2016, March), Blockchain applications for healthcare,
[Online]. Available: http://www.cio.com/article/3042603/innovation/
blockchain-applications-for-healthcare.html.
[11] World Health Organization, “Growing threat from counterfeit
medicines,“ Bulletin of the World Health Organization, vol. 88, no.4, pp.
241-320, April 2010.
[12] P. Taylor (2016, April), Applying blockchain technology to medicine
traceability, [Online]. Available: https://www.securingindustry.com/
pharmaceuticals/applying-blockchain-technology-to-medicine-
traceability/s40/a2766/#.V5mxL_mLTIV.
2016 IEEE 18th International Conference on e-Health Networking, Applications and Services (Healthcom)

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P9 blockchain technology in healthcare

  • 1. Blockchain Technology in Healthcare The Revolution Starts Here Matthias Mettler M.A. HSG Boydak Strategy Consulting AG Freienbach, Switzerland mettler.matthias@bluewin.ch Abstract—Blockchain technology has shown its considerable adaptability in recent years as a variety of market sectors sought ways of incorporating its abilities into their operations. While so far most of the focus has been on the financial services industry, several projects in other service related areas such as healthcare show this is beginning to change. Numerous starting points for Blockchain technology in the healthcare industry are the focus of this report. With examples for public healthcare management, user-oriented medical research and drug counterfeiting in the pharmaceutical sector, this report aims to illustrate possible influences, goals and potentials connected to this disruptive technology. Keywords—Blockchain, new business models, digitalization, healthcare, digital health, health information management, medical treatment, patient data, medical research, counterfeit drugs I. INTRODUCTION Blockchain is causing a hype and optimism that has rarely been seen in the history of technology. It is celebrated as a new technological revolution, which will have at least as large an impact on society as the invention of the wheel, the steam engine or the Internet. In a World Economic Forum report released in September 2015, 58 percent of all survey respondents said that they expected that by the year 2025, 10 percent of global gross domestic product will be stored using Blockchain technology [1]. It is therefore not surprising that Blockchain is attracting throngs of investors who are extensively investing in Blockchain startups. The investments amounted to almost half a billion dollars in 2015 [2] – the trend increasing. Nevertheless, the approaches, objectives and potentials of Blockchain are still largely unknown throughout society. II. BITCOINS AS A STARTING POINT FOR THE DEVELOPMENT OF BLOCKCHAIN Blockchain was originally developed for the crypto- currency Bitcoin and first described in Satoshi Nakamoto's (pseudonym) whitepaper in 2008. In the document, Nakamoto particularly addresses the challenge of ownership related to digital currencies and proposes a solution using a Blockchain prior to the settlement of transactions [3]. The functional principle of the Blockchain can be explained using the concept of such Bitcoin transactions. The Bitcoin Blockchain can be considered as a cohesive collection of digital wallets [4]. If a Bitcoin transaction, for example, is made from wallet A to wallet B, this information is simultaneously shared with all other wallets in the underlying Bitcoin Blockchain. The information on a Bitcoin transaction (e.g. transferred sum, ownership, etc.) are combined in an information block, marked with a timestamp and added as a new block to the existing Bitcoin Blockchain. At the same time, the transaction is verified and confirmed by all involved wallets. Due to this continuous sequence of blocks of information, the information with respect to all transactions made in the past, at any given time, are completely transparent and literally tamper-proof [4] [5]. Put simply, the solution of ownership associated with Bitcoins as published by Satoshi Nakamoto [3], therefore, lies in consolidating all necessary information in a single database, which is then publicly distributed [4] [5]. A database that does not claim any ownership and simultaneously, everyone owns. The content of this decentralized database is available to all parties involved. Furthermore, since all transactions are processed by users via a particular pseudonym, the information contained in the Bitcoin Blockchain is completely anonymous [4] [5]. III. BLOCKCHAIN POTENTIAL EXTENDS FAR BEYOND THE FINANCIAL SECTOR The Bitcoin Blockchain example clearly shows that Blockchain technology represents an approach as to how ownership of digital goods can be achieved. The underlying principle of decentralized, transparent and instant access to information represents a starting point for many market sectors [5] [6]. This may also be considered a reason why, in recent years, Blockchain has continued to develop both within and outside of the financial sector. Consequently, there are some interesting examples outside of the financial sector. Startups like Ujo or Peertraks offer a new approach, such as how music rights can be administered and enforced using Blockchain. Or at Stampery, for example, contracts, emails and documents can be signed digitally and smart contracts can be settled. Also, in the healthcare industry there are various possibilities: for example, in (public) health management, in the pharmaceutical sector, in medical research or in consumer- 2016 IEEE 18th International Conference on e-Health Networking, Applications and Services (Healthcom) 978-1-5090-3370-6/16/$31.00 ©2016 IEEE
  • 2. oriented healthcare [6]. Below there are certain examples from the healthcare industry which highlight the importance of Blockchain and its functionality. IV. SMART HEALTHCARE MANAGEMENT FOR THE BENEFIT OF THE PATIENT A decentralized database which is consistently held up to date presents many advantages to the healthcare industry. These advantages become especially interesting, when many different parties need access to the same information [6] [7] [8]. Medical treatment processes, for example in the area of elderly care or chronic diseases, are predestined fields of application where Blockchain technology can create added value. A variety of involved parties (e.g., general practitioners, medical specialists, hospitals, therapists, etc.) and the amount of media disruptions involved during the treatment of a patient (e.g., change of communication media, various medical health records, incompatible IT interfaces, etc.) can lead to time- consuming and resource-intensive authentication and information processes for all medical stakeholders involved [6]. For example, Gem, a US startup, is actively involved in this area and, therefore, launched the Gem Health Network based on the Ethereum Blockchain technology [7]. Through this shared network infrastructure, different healthcare specialists can access the same information. This will also permit the development of a new class of Blockchain-based applications in healthcare that will unlock wasted resources and solve important operational problems [7]. Therefore, the Gem Health Network represents a healthcare ecosystem that combines both businesses, individuals and experts and which, at the same time, improve patient-centered care while address operational efficiency issues. This network is thus an example of a Blockchain approach that provides all relevant medical stakeholders transparent and clear access to the latest treatment information. On the one hand, this can limit medical negligence due to outdated information and thereby prevent health issues in an early stage. This can lead to extensive savings in merit costs. On the other hand, it allows medical experts involved to track the interactions between the patient and all physicians which have taken place in the past. Consequently, the entire treatment of a patient is characterized in a transparent manner, whereby a completely new information and confidence level between all medical stakeholders is created. The fact that this logic proves itself correct not only for direct patient-physician relationships, can be demonstrated by the example of Estonia’s digital health infrastructure. In 2011, Estonia collaborated with Guardtime which operates a healthcare platform based on Blockchain technology [9]. Since then, Estonian citizens, healthcare providers or health insurance companies have been able to retrieve all information on medical treatments performed in Estonia by using the Guardtime Blockchain [9]. Estonia thus has proven that a complete public health infrastructure can be operated using Blockchain. V. BLOCKCHAIN EMPOWERS END USERS RESPECTIVELY PATIENTS IN HEALTHCARE Data is the new gold – this also applies to patient-generated health data. The abundance of available worldwide health apps and health wearables leads to a powerful flood of data, which can be used for medical issues related research. Blockchain offers various application possibilities in the field of patient- generated health data [6]. For example, healthbank, a global Swiss digital health startup, takes a radically new approach when it comes to the handling of data transactions and sharing of personal health data. This startup offers its users a platform on which they can store and manage their health information in a secure environment [10]. The data sovereignty lies fully in the hands of the user. As a next step, healthbank plans to consistently apply and implement Blockchain technology for the underlying business model [10]. Using Blockchain, in the future, personal patient-generated health data (e.g., heart rate, blood pressure, medicines taken, sleep patterns, eating habits etc.) can be retrieved from health apps, wearables or physician visits and be securely stored in the healthbank Blockchain. Already today, healthbank users are not only able to save their data on the platform, but can also make it available for medical research. In return, they receive specific financial compensation for their data provided. Healthbank thereby becomes a unique data-trading platform, with which new opportunities in patient-oriented research are made available (e.g., in clinical trials for the pharmaceutical industry, in academic research projects at universities, etc.). Using Blockchain, this model could be even further individualized in a way that personal patient-generated health data which is available to researchers can be tracked in the research process with a timestamp (e.g., analogue to the described Bitcoin transaction) [6] [8]. Healthbank users who have significantly contributed to the success of medical research projects could be identified using Blockchain and rewarded at a higher level than the average. Healthbank has thereby become a symbol of end user respectively patient empowerment in healthcare which rides alongside digitalization, new digital business models and digital health initiatives. Blockchain technology will further boost this end user and patient empowerment in healthcare. VI. USING BLOCKCHAIN TO FIGHT COUNTERFEIT DRUGS IN THE PHARMACEUTICAL INDUSTRY Wherever products are subject to a sensitive production process and where extensive reputational and liability issues are associated with the final product, the benefits of Blockchain are evident. Therefore, the research, development 2016 IEEE 18th International Conference on e-Health Networking, Applications and Services (Healthcom)
  • 3. and production of drugs in the pharmaceutical sector is a further field of application for Blockchain technology. Corresponding to the previously described example referring to Bitcoin transactions via Blockchain, this technology can also be used to monitor the production processes for drugs. In this context, the issue of counterfeit medicine is an urgent and increasingly acute worldwide issue. According to the World Health Organization, ten percent of drugs are counterfeit worldwide, in developing countries the number rises up to 30 percent [11]. Such counterfeit drugs often do not only affect so-called lifestyle products (e.g., muscle building supplements, potency stimulants, slimming products, etc.), but also drugs for the treatment of cardiovascular disorders and cancer, antibiotics, painkillers, contraceptives and other prescription drugs [11]. Such counterfeits can contain the correct active ingredient, but in most cases show a dose which is too high or too low or which are produced in an impure manner. It then becomes extremely dangerous for the human organism when there is no trace of the expected active substance in the forged drug [11]. Hyperledger, a research network across industries, recently launched the Counterfeit Medicines Project [12]. The project especially focuses on the issue of drug counterfeiting and is one of the current use cases within the research network, in which Accenture, Cisco, Intel, IBM, Block Stream and Bloomberg are involved [12]. As part of this project, each drug produced is marked with a timestamp. Firstly, thanks to this approach, it is possible to determine when and where the drug was produced at any given time. Secondly, such an approach can be specifically used to fight the production of counterfeit drugs. Using Blockchain, the origin of the product and its components are detected, and any transfer of ownership in each case is made clear and available to everyone. Forged, poor quality or stolen goods can be tracked and identified. In this field of application, Blockchain contributes to ensuring that safety in relation to drugs is increased, and health-related follow-up costs are reduced. VII. CONCLUSION The examples described, show that Blockchain offers numerous opportunities for usage in the healthcare sector, e.g. in public health management, user-oriented medical research based on personal patient data as well as drug counterfeiting. The immense potential of this technology shows up wherever, until now, a trusted third party was necessary for the settlement of market services. With Blockchain, direct transactions suddenly become possible, whereby a central actor, who controlled the data, earned commission or even intervened in a censoring fashion, can be eliminated. This disruptive character, which underlies Blockchain technology, will strongly affect the balance of power between existing market players in healthcare. It will also promote new digital business models and digital health initiatives. Due to the fact that, in the future, (data) intermediaries can be avoided, this technology opens new doors with respect to how market interactions in healthcare can be conducted. Blockchain thus has an immense potential for the future and will show disruptive changes in the healthcare industry. REFERENCES [1] World Economic Forum (2015, September). Deep Shift. Technology Tipping Points and Societal Impact, [Online]. Available: http://www3.weforum.org/docs/WEF_GAC15_Technological_Tipping_ Points_report_2015.pdf. [2] E. Maras (2016, March), VC Fintech Funding Sets Record In 2015, [Online]. Available: https://www.cryptocoinsnews.com/vc-fintech- funding-sets-record-2015-fueling-bitcoin-blockchain-growth/ [3] N. Satoshi (2008), Bitcoin: A Peer-to-Peer Electronic Cash System, [Online]. Available: https://bitcoin.org/bitcoin.pdf [4] G. Dwyer. “The economics of Bitcoin and similar private digital currencies,” Journal of Financial Stability, vol. 17, pp. 81-91, April 2015. [5] R. Böhme, N. Christin, B. Edelman, and T. Moore. “Bitcoin: Economics, Technology, and Governance,” Journal of Economic Perspectives, vol. 29, no. 2, pp. 213-38, May 2015. [6] M. Swan, Blockchain: Blueprint for a new economy. O'Reilly Media, Inc., 2015. [7] G. Prisco (2016, April), The Blockchain for Healthcare: Gem Launches Gem Health Network With Philips Blockchain Lab, [Online]. Available: https://bitcoinmagazine.com/articles/the-blockchain-for-heathcare-gem- launches-gem-health-network-with-philips-blockchain-lab-1461674938 [8] G. Irving, H. John (2016, May), How blockchain-timestamped protocols could improve the trustworthiness of medical science. [Online]. Available: http://f1000research.com/articles/5-222/v2 [9] O. Williams-Grut (2016, March), Estonia is using the technology behind bitcoin to secure 1 million health records, [Online]. Available: http://www.businessinsider.com/guardtime-estonian-health-records- industrial-blockchain-bitcoin-2016-3?r=UK&IR=T. [10] P. B. Nichol (2016, March), Blockchain applications for healthcare, [Online]. Available: http://www.cio.com/article/3042603/innovation/ blockchain-applications-for-healthcare.html. [11] World Health Organization, “Growing threat from counterfeit medicines,“ Bulletin of the World Health Organization, vol. 88, no.4, pp. 241-320, April 2010. [12] P. Taylor (2016, April), Applying blockchain technology to medicine traceability, [Online]. Available: https://www.securingindustry.com/ pharmaceuticals/applying-blockchain-technology-to-medicine- traceability/s40/a2766/#.V5mxL_mLTIV. 2016 IEEE 18th International Conference on e-Health Networking, Applications and Services (Healthcom)